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News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 2976-3000 out of 3754.

<< < 115 | 116 | 117 | 118 | 119 | 120 | 121 | 122 | 123 | 124 > >>

Public Release: 22-Sep-2014
Cell Reports
Massachusetts General study reveals gene expression patterns in pancreatic CTCs
Analysis of circulating tumor cells in a mouse model of pancreatic cancer identified distinct patterns of gene expression in several groups of CTCs, including significant differences from the primary tumor that may contribute to the ability to generate metastases. The Massachusetts General Hospital Cancer Center investigators identified several different classes of pancreatic CTCs and found unexpected factors that may prove to be targets for improved treatment of the deadly tumor.
Stand Up to Cancer, Howard Hughes Medical Institute, Burroughs Wellcome Fund, NIH/National Institute of Biomedical Imaging and Bioengineering, NIH/National Cancer Institute, Affymetrix, Inc.

Contact: Katie Marquedant
Massachusetts General Hospital

Public Release: 22-Sep-2014
Journal of Controlled Release
New chip promising for tumor-targeting research
Researchers have developed a chip capable of simulating a tumor's 'microenvironment' and plan to use the new system to test the effectiveness of nanoparticles and drugs that target cancer.
National Science Foundation, National Institutes of Health

Contact: Emil Venere
Purdue University

Public Release: 22-Sep-2014
Proceedings of the National Academy of Sciences
Genetic switch regulates a plant's internal clock based on temperature
Scientists have found the molecular cog in a plant's biological clock that modulates its speed based on temperature.
The Ruth L. Kirschstein National Research Service Award, National Instiutes of Health, NIH/National Institute of General Medical Sciences

Contact: Robert Perkins
University of Southern California

Public Release: 22-Sep-2014
Rutgers receives $2 million grant to prepare biomedical students for roles in industry
Rutgers' School of Engineering and Rutgers Graduate School of Biomedical Sciences are joint recipients of a $2 million 2014 BEST grant from the National Institutes of Health. Once upon a time, students seeking advanced degrees in the biomedical sciences generally expected to find careers in academia, and their mentors expected them to do so. No longer. Fewer than half of those students now end up in academia. So the National Institutes of Health created the BEST grant, aimed at preparing students for potential careers in industry and other non-academic areas.
National Institutes of Health

Contact: Rob Forman
Rutgers University

Public Release: 22-Sep-2014
Behavioral Brain Research
Compound from hops aids cognitive function in young animals
Xanthohumol, a type of flavonoid found in hops and beer, has been shown in a new study to improve cognitive function in young mice, but not in older animals. The findings are another step toward understanding, and ultimately reducing the degradation of memory that happens with age in many mammalian species, including humans.
National Institutes of Health

Contact: Kathy Magnusson
Oregon State University

Public Release: 22-Sep-2014
Proceedings of the National Academy of Sciences
Variability keeps the body in balance
Although the heart beats out a very familiar 'lub-dub' pattern that speeds up or slows down as our activity increases or decreases, the pattern itself isn't as regular as you might think. In fact, the amount of time between heartbeats can vary even at a 'constant' heart rate -- and that variability, doctors have found, is a good thing.
John G. Braun Professorship, Air Force Office of Scientific Research, National Science Foundation, Pfizer, National Institutes of Health, Institute of Collaborative Biotechnologies

Contact: Deborah Williams-Hedges
California Institute of Technology

Public Release: 22-Sep-2014
Brain, Behavior and Immunity
Obesity and stress pack a double hit for health
If you're overweight, you may be at greater risk for stress-related diseases like type 2 diabetes, cardiovascular disease and cancer, according to a new study by Brandeis University. In a recently published paper in Brain, Behavior and Immunity, Brandeis researchers observed that overweight and obese individuals have higher levels of stress-induced inflammation than those within a healthy weight-range.
American Federation of Aging Research, National Institutes of Health

Contact: Leah Burrows
Brandeis University

Public Release: 22-Sep-2014
Proceedings of the National Academy of Sciences
Platelets modulate clotting behavior by 'feeling' their surroundings
Platelets respond to surfaces with greater stiffness by increasing their stickiness, the degree to which they "turn on" other platelets and other components of the clotting system, Emory and Georgia Tech researchers found.
National Science Foundation, American Heart Association, NIH/National Heart Lung Blood Institute, NIH/National Eye Institute

Contact: Quinn Eastman
Emory Health Sciences

Public Release: 22-Sep-2014
Mammalian Genome
Lack of thyroid hormone blocks hearing development
Fatigue, weight gain, chills, hair loss, anxiety, excessive perspiration -- these symptoms are a few of the signs that the thyroid gland has gone haywire. Harnessing electron microscopy to track the inner hair cells of the cochlea in two groups of mice, new research from Tel Aviv University points to an additional complication caused by an imbalance in the thyroid gland: congenital deafness.
National Institutes of Health, I-CORE Gene Regulation in Complex Human Disease

Contact: George Hunka
American Friends of Tel Aviv University

Public Release: 22-Sep-2014
Proceedings of the National Academy of Sciences
Lego-like modular components make building 3-D 'labs-on-a-chip' a snap
Thanks to new Lego-like components developed by researchers at the University of Southern California Viterbi School of Engineering, it is now possible to build a 3-D microfluidic system (or 'lab-on-a-chip') quickly and cheaply by simply snapping together small modules by hand.
National Institutes of Health

Contact: Megan Hazle
University of Southern California

Public Release: 22-Sep-2014
JAMA Pediatrics
Cytomegalovirus linked to maternal breast milk in very-low-birth-weight infants
The primary source of postnatal infection with cytomagelovirus, a common virus usually without symptoms in very-low-birth-weight infants appeared to be maternal breast milk because no infections were linked to transfusions of cytomagelovirus-seronegative and leukoreduced blood products.
NIH/National Heart, Lung and Blood Institute

Contact: Holly Korschun
The JAMA Network Journals

Public Release: 22-Sep-2014
Proceedings of the National Academy of Sciences
The fine line between breast cancer and normal tissues
Researchers at Brigham and Women's Hospital have successfully tested a tool they developed that will help surgeons better distinguish cancerous breast tissue from normal tissue, thereby decreasing the chances for repeat operations.
National Institutes of Health

Contact: Marjorie Montemayor-Quellenberg
Brigham and Women's Hospital

Public Release: 22-Sep-2014
Journal of Experimental Medicine
New rules for anticancer vaccines
Scientists have found a way to find the proverbial needle in the cancer antigen haystack. The results have the potential to completely change current approaches to generating anticancer vaccines.
Cancer Research Institute NY, Northeastern Utilities, Connecticut Institute for Clinical and Translational Science, SPARK, National Science Foundation, National Institutes of Health, Life Technologies, USDA/National Institute of Food and Agriculture

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 22-Sep-2014
Journal of Autism and Developmental Disorders
Brainwave test could improve autism diagnosis and classification
A new study by researchers at Albert Einstein College of Medicine of Yeshiva University suggests that measuring how fast the brain responds to sights and sounds could help in objectively classifying people on the autism spectrum and may help diagnose the condition earlier. The paper was published today in the online edition of the Journal of Autism and Developmental Disabilities.
NIH/National Institute of Mental Health

Contact: Kim Newman
Albert Einstein College of Medicine

Public Release: 22-Sep-2014
American Journal of Epidemiology
Mothers of children with autism less likely to have taken iron supplements
Mothers of children with autism are significantly less likely to report taking iron supplements before and during their pregnancies than the mothers of children who are developing normally, a study by researchers with the UC Davis MIND Institute has found.
National Institutes of Health, US Environmental Protection Agency Science to Achieve Results

Contact: Phyllis Brown
University of California - Davis Health System

Public Release: 21-Sep-2014
Nature Nanotechnology
Engineered proteins stick like glue -- even in water
MIT researchers find new adhesives based on mussel proteins could be useful for naval or medical applications.
Office of Naval Research, National Science Foundation, National Institutes of Health

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 21-Sep-2014
Nature Biotechnology
Battling superbugs
Two new technologies from researchers at MIT could enable novel strategies for combating drug-resistant bacteria.
National Institutes of Health, Defense Threat Reduction Agency, US Army Research Laboratory, US Army Research Office, Office of Naval Research, The Ellison Foundation

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 21-Sep-2014
Journal of Allergy & Clinical Immunology
Dry roasting could help trigger peanut allergy
Dry roasted peanuts are more likely to trigger an allergy to peanuts than raw peanuts, suggests an Oxford University study involving mice. The researchers say that specific chemical changes caused by the high temperatures of the dry roasting process are recognized by the body's immune system, 'priming' the body to set off an allergic immune response the next time it sees any peanuts.
NIH/National Institute for Health Research, Oxford Biomedical Research Centre, National Institutes of Health, Swiss National Science Foundation

Contact: University of Oxford News & Information Office
University of Oxford

Public Release: 21-Sep-2014
Nature Methods
Program predicts placement of chemical tags that control gene activity
Biochemists have developed a program that predicts the placement of chemical marks that control the activity of genes based on sequences of DNA. By comparing sequences with and without epigenomic modification, they identified DNA motifs associated with the changes. They call this novel analysis pipeline Epigram and have made both the program and the DNA motifs they identified openly available to other scientists.
NIH/National Institute of Environmental Health Sciences

Contact: Susan Brown
University of California - San Diego

Public Release: 20-Sep-2014
University of Southern California researchers reveal how gene expression affects facial expressions
A person's face is the first thing that others see, and much remains unknown about how it forms -- or malforms -- during early development. Recently, Chong Pyo Choe, a senior postdoctoral fellow working in the lab of University of Southern California stem cell researcher Gage Crump, has begun to unwind these mysteries.
NIH/National Institute of Dental and Craniofacial Research, California Institute for Regenerative Medicine

Contact: Cristy Lytal
University of Southern California - Health Sciences

Public Release: 19-Sep-2014
Genes & Development
Scientists discover an on-off switch for aging cells
Scientists at the Salk Institute have discovered an on-and-off 'switch' in cells that may hold the key to healthy aging. This switch points to a way to encourage healthy cells to keep dividing and generating, for example, new lung or liver tissue, even in old age.
National Institutes of Health, Fritz B. Burns Foundation, Rose Hills Foundation

Contact: Salk Communications
Salk Institute

Public Release: 19-Sep-2014
Cancer Cell
New cancer drug target involving lipid chemical messengers
More than half of human cancers have abnormally upregulated chemical signals related to lipid metabolism, yet how these signals are controlled during tumor formation is not fully understood. Researchers report that TIPE3, a newly described oncogenic protein, promotes cancer by targeting these pathways.
NIH/National Institute of Allergy and Infectious Diseases, NIH/National Institute of General Medical Sciences

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 19-Sep-2014
Magnetic Resonance in Medicine
A better way to track emerging cell therapies using MRIs
In a paper published Sept. 17 in the online journal Magnetic Resonance in Medicine, researchers at the University of California, San Diego School of Medicine, University of Pittsburgh and elsewhere describe the first human tests of using a perfluorocarbon tracer in combination with non-invasive magnetic resonance imaging to track therapeutic immune cells injected into patients with colorectal cancer.
National Institutes of Health

Contact: Scott LaFee
University of California - San Diego

Public Release: 19-Sep-2014
PLOS Currents: Outbreaks
Research predicts possible 6,800 new Ebola cases this month
Arizona State University and Harvard University researchers also discovered through modelling analysis that the rate of rise in cases significantly increased in August in Liberia and Guinea, around the time that a mass quarantine was put in place, indicating that the mass quarantine efforts may have made the outbreak worse than it would have been otherwise.
NIH/National Institute of General Medical Sciences

Contact: Julie Newberg
Arizona State University

Public Release: 19-Sep-2014
Mayo researchers reveal pathway that contributes to Alzheimer's disease
Researchers at Jacksonville's campus of Mayo Clinic have discovered a defect in a key cell-signaling pathway they say contributes to both overproduction of toxic protein in the brains of Alzheimer's disease patients as well as loss of communication between neurons -- both significant contributors to this type of dementia.
National Institutes of Health, Alzheimer's Association, Mayo Clinic

Contact: Kevin Punsky
Mayo Clinic

Showing releases 2976-3000 out of 3754.

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