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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 2976-3000 out of 3542.

<< < 115 | 116 | 117 | 118 | 119 | 120 | 121 | 122 | 123 | 124 > >>

Public Release: 31-Jan-2014
Genes & Development
Fruit flies reveal normal function of a gene mutated in spinocerebellar ataxia type 7
Disruptive clumps of mutated protein are often blamed for clogging cells and interfering with brain function in patients with the neurodegenerative diseases known as spinocerebellar ataxias. But a new study in fruit flies suggests that, for at least one of these diseases, the defective proteins may not need to form clumps to do harm.
Stowers Institute and National Institutes of Health

Contact: Gina Kirchweger
gxk@stowers.org
816-806-1036
Stowers Institute for Medical Research

Public Release: 30-Jan-2014
Human Brain Mapping
Imaging technique shows brain anatomy change in women with multiple sclerosis, depression
A multicenter research team led by Cedars-Sinai neurologist Nancy Sicotte, MD, an expert in multiple sclerosis and state-of-the-art imaging techniques, used a new, automated technique to identify shrinkage of a mood-regulating brain structure in a large sample of women with MS who also have a certain type of depression.
National Institutes of Health, NIH/National Institute on Aging, Cousins Center for Psychoneuroimmunology, European Union/Marie Curie Grant, Skirball Foundation, US Department of Defense

Contact: Sandy Van
sandy@prpacific.com
808-526-1708
Cedars-Sinai Medical Center

Public Release: 30-Jan-2014
Cancer Discovery
Study reports success in targeted therapy for common form of lung cancer
Dana-Farber researchers have found that a combination of two already-in-use drugs may have an effect on stopping the growth of the most common genetic subtype of lung cancer setting the stage for clinical trials.
National Institutes of Health, V Foundation, GTM Fund for Lung Cancer Research

Contact: Robbin Ray
Robbin_ray@dfci.harvard.edu
617-632-4090
Dana-Farber Cancer Institute

Public Release: 30-Jan-2014
Journal of Molecular Diagnostics
RI Hospital researchers identify components in C. diff that may lead to better treatment
Rhode Island Hospital researchers have identified components in Clostridium difficile (C. diff) that may lead to new diagnostic tools, and ultimately more timely and effective treatment for this often fatal infection. C. diff is a spore-forming bacterium that causes severe diarrhea and is responsible for 14,000 deaths annually in the US.
National Science Foundation, National Institutes of Health

Contact: Ellen Slingsby
eslingsby@lifespan.org
401-444-6421
Lifespan

Public Release: 30-Jan-2014
Psychosomatic Medicine
USF psychologist: Childhood depression may increase risk of heart disease by teen years
Children with depression are more likely to be obese, smoke and be inactive, and can show the effects of heart disease as early as their teen years, according to a newly published study by University of South Florida associate professor of psychology Jonathan Rottenberg.
National Institutes of Health

Contact: Adam Freeman
adamfreeman@usf.edu
813-974-9047
University of South Florida (USF Health)

Public Release: 30-Jan-2014
Menopause
Penn study finds more than a third of women have hot flashes 10 years after menopause
Moderate to severe hot flashes continue, on average, for nearly five years after menopause, and more than a third of women experience moderate/severe hot flashes for 10 years or more after menopause. Current guidelines recommend that hormone therapy, the primary medical treatment for hot flashes, not continue for more than five years. However, in the new study, the authors write that "empirical evidence supporting the recommended three- to five-year hormone therapy for management of hot flashes is lacking."
National Institutes of Health

Contact: Katie Delach
katie.delach@uphs.upenn.edu
215-349-5964
University of Pennsylvania School of Medicine

Public Release: 30-Jan-2014
Annals of Behavioral Medicine
Does caregiving cause psychological stress? UW study of female twins says it depends
The study, "Does caregiving cause psychological distress? The case for familial and genetic vulnerabilities in female twins," was published in the Annals of Behavioral Medicine in January 2014 and showed that the associations between caregiving and different types of psychological distress (depression, anxiety, perceived stress and perceived mental health) depend largely on a person's genes and upbringing -- and less so on the difficulty of caregiving.
National Institutes of Health

Contact: bobbi nodell
bnodell@uw.edu
206-271-1429
University of Washington Health Sciences/UW Medicine

Public Release: 30-Jan-2014
Cancer Research
Protein serves as a natural boost for immune system fight against tumors
Different molecular adjuvants, such as cytokines, are being studied as a way to increase the efficacy of vaccines. The development of DNA-based vaccines with cytokine adjuvants has emerged as particularly promising for inducing antiviral and anti-tumor, cell-mediated immune responses. The protein IL-33 boosts the immune system of a human papilloma virus animal model of cancer.
Basser Research Center for BRCA, National Institutes of Health

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 30-Jan-2014
Scripps scientist awarded $1.8 million to develop new approaches to lung cancer therapy
Scientists from the Florida campus of The Scripps Research Institute have been awarded approximately $1.8 million from the National Cancer Institute of the National Institutes of Health to identify the signaling pathways that underlie lung cancer and to use this information to develop new therapeutic approaches.
NIH/National Cancer Institute

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute

Public Release: 30-Jan-2014
Cell
Worry on the brain
Previous studies of anxiety in the brain have focused on the amygdala, but a team of researchers led by biologists at Caltech had a hunch that understanding a different brain area, the lateral septum, could provide more clues into how the brain processes anxiety. Their instincts paid off -- the team has found a neural circuit that connects the LS with other brain structures in a manner that directly influences anxiety.
National Institutes of Health, Howard Hughes Medical Institute, Beckman Institute at Caltech

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology

Public Release: 30-Jan-2014
Cell
Researchers reverse some lung diseases in mice by coaxing production of healthy cells
Introducing proteins that direct lung stem cells to grow the specific cell types needed to repair lung injuries could lead to new ways to treat some lung diseases, according to research from Boston Children's Hospital published in the journal Cell.
Hope for Funds Cancer Research, NIH/National Heart, Lung, and Blood Institute, and others

Contact: Irene Sege
irene.sege@childrens.harvard.edu
617-919-7379
Boston Children's Hospital

Public Release: 30-Jan-2014
Cell Reports
Zebra fish fins help Oregon researchers gain insight into bone regeneration
University of Oregon biologists say they have opened the window on the natural process of bone regeneration in zebra fish, and that the insights they gained could be used to advance therapies for bone fractures and disease.
National Institutes of Health

Contact: Jim Barlow
jebarlow@uoregon.edu
541-346-3481
University of Oregon

Public Release: 30-Jan-2014
BioDataMining
Dartmouth researchers develop new tool to identify genetic risk factors
Dartmouth researchers developed a new biological pathway-based computational model, called the Pathway-based Human Phenotype Network, to identify underlying genetic connections between different diseases as reported in BioDataMining this week. The Pathway-based Human Phenotype Network mines the data present in large publicly available disease datasets to find shared SNPs, genes, or pathways and expresses them in a visual form.
National Institutes of Health

Contact: Donna Dubuc
Donna.M.Dubuc@Dartmouth.edu
603-653-3615
The Geisel School of Medicine at Dartmouth

Public Release: 30-Jan-2014
PLOS Genetics
Discovery may lead to new drugs for osteoporosis
Scientists at Washington University School of Medicine in St. Louis have discovered what appears to be a potent stimulator of new bone growth. The finding could lead to new treatments for osteoporosis and other diseases that occur when the body doesn't make enough bone.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine

Public Release: 30-Jan-2014
Nature
A protein-production tale of the tape
Whitehead Institute researchers have determined that poly(A) tails on messenger RNAs shift their role in the regulation of protein production during early embryogenesis. This finding about the regulation of messenger RNA translation also provides insight into how microRNAs control protein production.
National Institutes of Health

Contact: Nicole Rura
rura@wi.mit.edu
617-258-6851
Whitehead Institute for Biomedical Research

Public Release: 30-Jan-2014
Science
UCSF team reveals how the brain recognizes speech sounds
UC San Francisco researchers are reporting a detailed account of how speech sounds are identified by the human brain. The finding, they said, may add to our understanding of language disorders, including dyslexia.
National Institutes of Health, Ester A. and Joseph Klingenstein Fund

Contact: Peter Farley
peter.farley@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 30-Jan-2014
Journal of Investigative Medicine
Gastric banding patients should closely monitor nutrition following surgery
Patients who have had bariatric surgery may need to take dietary supplements and pay closer attention to their nutritional intake, a UT Southwestern Medical Center study suggests.
National Institutes of Health, Southwestern Medical Foundation

Contact: Debbie Bolles
debbie.bolles@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center

Public Release: 30-Jan-2014
Cell
How DNA damage affects Golgi -- the cell's shipping department
In studying the impact of DNA damage on the Golgi, a research team from the University of California, San Diego School of Medicine and the Ludwig Institute for Cancer Research have discovered a novel pathway activated by DNA damage, with important consequences for the body's cellular response to chemotherapy.
National Institutes of Health, American Cancer Society

Contact: Debra Kain
ddkain@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 30-Jan-2014
Cell
Cell cycle speed is key to making aging cells young again
Yale School of Medicine researchers identified a major obstacle to converting cells back to their youthful state -- the speed of the cell cycle, or the time required for a cell to divide. When the cell cycle accelerates to a certain speed, the barriers that keep a cell's fate on one path diminish. In such a state, cells are easily persuaded to change their identity and become pluripotent, or capable of becoming multiple cell types.
National Institutes of Health, Connecticut Stem Cell Research Program

Contact: Bill Hathaway
william.hathaway@yale.edu
203-432-1322
Yale University

Public Release: 30-Jan-2014
Stroke: Journal of the American Heart Association
Video game teaches kids about stroke symptoms and calling 9-1-1
Children improved their knowledge of stroke symptoms and how to respond after playing a stroke education video game. They retained that knowledge for several weeks.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Darcy Spitz
darcy.spitz@heart.org
212-878-5940
American Heart Association

Public Release: 30-Jan-2014
Cancer Prevention Research
New data contradict current recommendations for management of breast biopsy abnormalities
Contrary to existing understanding, long-term follow-up of patients with two types of breast tissue abnormalities suggests that both types of abnormalities have the same potential to progress to breast cancer, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research. Findings from this study could improve clinical management of patients with breast tissue abnormalities.
National Institutes of Health, Susan G. Komen

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research

Public Release: 30-Jan-2014
Science
Scientists discover new genetic forms of neurodegeneration
In a study published in the Jan. 31, 2014, issue of Science, an international team led by scientists at the University of California, San Diego, School of Medicine report doubling the number of known causes for the neurodegenerative disorder known as hereditary spastic paraplegia. The disorder is characterized by progressive stiffness and contraction of the lower limbs and is associated with epilepsy, cognitive impairment, blindness and other neurological features.
Deutsche Forschungsgemeinschaft, Brain & Behavior Research Foundation, and National Institutes of Health

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 29-Jan-2014
Proceedings of the National Academy of Sciences
Findings point to potential treatment for virus causing childhood illnesses
Researchers have discovered a potential treatment for a viral infection that causes potentially fatal brain swelling and paralysis in children. The findings also point to possible treatments for related viruses including those that cause "common cold" symptoms.
National Institutes of Health

Contact: Emil Venere
venere@purdue.edu
765-494-4709
Purdue University

Public Release: 29-Jan-2014
Nature
Puzzling question in bacterial immune system answered
Berkeley researchers have answered a central question about Cas9, an enzyme that plays an essential role in the bacterial immune system and is fast becoming a valuable tool for genetic engineering: How is Cas9 able to precisely discriminate between non-self DNA that must be degraded and self DNA that may be almost identical within genomes that are millions to billions of base pairs long.
National Science Foundation, National Institutes of Health

Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory

Public Release: 29-Jan-2014
Progress in Community Health Partnerships: Research, Education and Action
U of Maryland study: Partnership may help address cancer, health disparities
Robust partnerships between rural community health education centers and academic health care institutions can make substantial strides toward addressing race-, income- and geographically based health disparities in underserved communities by empowering both the community and leading University institutions, according to newly published research from the University of Maryland School of Medicine.
NIH/National Cancer Institute, NIH/National Institute on Minority Health and Health Disparities

Contact: Christopher Hardwick
chardwick@som.umaryland.edu
410-706-5260
University of Maryland Medical Center

Showing releases 2976-3000 out of 3542.

<< < 115 | 116 | 117 | 118 | 119 | 120 | 121 | 122 | 123 | 124 > >>

     
   

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