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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 2976-3000 out of 3555.

<< < 115 | 116 | 117 | 118 | 119 | 120 | 121 | 122 | 123 | 124 > >>

Public Release: 27-Feb-2014
Gene Therapy
Cancer vaccine could use immune system to fight tumors
Cincinnati Cancer Center and University of Cincinnati Cancer Institute researchers have found that a vaccine, targeting tumors that produce a certain protein and receptor responsible for communication between cells and the body's immune system, could initiate the immune response to fight cancer.
NIH/National Cancer Institute, LCS Foundation Cincinnati, University of CincinnatiNIH/National Cancer Institute, LCS Foundation Cincinnati, University of Cincinnati

Contact: Katie Pence
University of Cincinnati Academic Health Center

Public Release: 27-Feb-2014
Internal logic: 8 distinct subnetworks in mouse cerebral cortex
The mammalian cerebral cortex, long thought to be a dense single interrelated tangle of neural networks, actually has a 'logical' underlying organizational principle. Researchers have identified eight distinct neural subnetworks that together form the connectivity infrastructure of the mammalian cortex, the part of the brain involved in higher-order functions such as cognition, emotion and consciousness.
NIH/National Institute of Mental Health

Contact: Suzanne Wu
University of Southern California

Public Release: 27-Feb-2014
Cell Reports
Yale study provides a breath of hope for pulmonary hypertension patients
Most of us draw roughly 25,000 breaths a day without any thought. But for patients with pulmonary hypertension, a life-threatening increase in blood pressure in the lungs, even the smallest task can leave them gasping for air. A new study by researchers at Yale School of Medicine offers insight into the function of cells linked to this incurable and often fatal illness.
National Institutes of Health, American Lung Association, March of Dimes, CTSA, National Center for Advancing Translational Science, Pulmonary Hypertension Association

Contact: Karen N. Peart
Yale University

Public Release: 26-Feb-2014
European Journal of Pharmacology
Low birth weight reduces ability to metabolize drugs
Researchers have identified another concern related to low birth weight -- a difference in how the body reacts to drugs, which may last a person's entire life and further complicate treatment of illnesses or diseases that are managed with medications.
National Institutes of Health

Contact: Ganesh Cherala
Oregon State University

Public Release: 26-Feb-2014
Brain Pathology
After death, twin brains show similar patterns of neuropathologic changes
Study on the brains of twins finds that Alzheimer's disease is actually a diverse collection of diseases, symptoms and pathological changes.
National Institutes of Health

Contact: Edward North-Hager
University of Southern California

Public Release: 26-Feb-2014
UNC receives more than $40 million for global clinical trials unit to treat and prevent HIV
A more than $40 million grant from the NIH will support five clinical research sites in the Unites States and sub-Saharan Africa that will lead clinical research to address HIV treatment, prevention, and cure.
National Institutes of Health

Contact: Lisa Chensvold
University of North Carolina Health Care

Public Release: 26-Feb-2014
Molecular Cell
Fox Chase researchers discover new mechanism of gene regulation
Additional insights into how cancer cells use PARP1 enzyme to resist current therapies may also point to the next generation of cancer drugs.
National Institutes of Health

Contact: Diana Quattrone
Fox Chase Cancer Center

Public Release: 26-Feb-2014
Mayo Clinic discovers African-Americans respond better to rubella vaccine
Somali Americans develop twice the antibody response to rubella from the current vaccine compared to Caucasians in a new Mayo Clinic study on individualized aspects of immune response. A non-Somali, African-American cohort ranked next in immune response, still significantly higher than Caucasians, and Hispanic-Americans in the study were least responsive to the vaccine. The findings appear in the journal Vaccine.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Bob Nellis
Mayo Clinic

Public Release: 26-Feb-2014
New data book outlines Hispanic/Latino health
The National Heart, Lung, and Blood Institute, part of the National Institutes of Health, released the largest and most comprehensive health and lifestyle analysis of people from a range of Hispanic/Latino origins. The data will enable individuals, communities, and policy makers to tailor better health intervention strategies.
NIH/National Heart, Lung, and Blood Institute

Contact: Natalia Elko
San Diego State University

Public Release: 26-Feb-2014
Tobacco Control
Secondhand smoke exposure linked to adverse pregnancy outcomes
Secondhand smoking is linked with pregnancy loss, including miscarriage, stillbirth and tubal ectopic pregnancy, according to new research from scientists at Roswell Park Cancer Institute and the University at Buffalo. The study findings, published online by the journal Tobacco Control, mark a significant step toward clarifying the risks of secondhand smoke exposure.
National Institutes of Health

Contact: John DellaContrada
University at Buffalo

Public Release: 26-Feb-2014
Humans have a poor memory for sound
According to a new study from researchers at the University of Iowa, our memory for sounds is significantly worse than our memory for visual or tactile things. Results are published in the open-access journal PLOS ONE.
NIH/National Institute on Deafness and Other Communication Disorders

Contact: Amy Mattson
University of Iowa

Public Release: 26-Feb-2014
Journal of Synchrotron Radiation
Nanoscale freezing leads to better imaging
New X-ray tool allows for more sensitivity to trace metals, such as those that cause cancer, in whole cells and tissues.
National Institutes of Health, Department of Energy

Contact: Tona Kunz
DOE/Argonne National Laboratory

Public Release: 26-Feb-2014
Proceedings of the National Academy of Sciences
UNC researchers team up to find new target for dengue virus vaccine
Using an experimental technique new to the dengue field, UNC researchers showed that a molecular hinge where two regions of a protein connect is where natural human antibodies attach to dengue type-3 to disable it. The finding shows that most human antibodies that neutralize the virus bind to this hinge. It's the first study to demonstrate how these binding sites can be genetically exchanged without disrupting the integrity of the virus.
National Institutes of Health

Contact: Mark Derewicz
University of North Carolina Health Care

Public Release: 26-Feb-2014
Journal of Neuroscience
Exercise, surgically removing belly fat improves cognition in obese, diabetic mice
Cognitive decline that often accompanies obesity and diabetes can be reversed with regular exercise or surgical removal of belly fat, scientists report. A drug already used to treat rheumatoid arthritis also helps obese/diabetic adult mice regain their ability to learn and comprehend, while transplanting belly fat to a normal mouse reduces those abilities, said Dr. Alexis M. Stranahan, neuroscientist at the Medical College of Georgia at Georgia Regents University.
NIH/National Institute of Diabetes, Digestive and Kidney Diseases

Contact: Toni Baker
Medical College of Georgia at Georgia Regents University

Public Release: 26-Feb-2014
Obesity Research & Clinical Practice
Attitude during pregnancy affects weight gain
Overweight or obese women with the mentality that they are 'eating for two' are more likely to experience excessive weight gain while pregnant, according to researchers at Penn State College of Medicine.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH/National Center for Research Resources, NIH/National Center for Advancing Translational Sciences

Contact: Matthew Solovey
Penn State

Public Release: 26-Feb-2014
Self-administration of flu vaccine with a patch may be feasible, study suggests
The annual ritual of visiting a doctor's office or health clinic to receive a flu shot may soon be outdated, thanks to the findings of a new study published in the journal Vaccine.
National Institutes of Health, NIH/National Institute of Biomedical Imaging and Bioengineering

Contact: John Toon
Georgia Institute of Technology

Public Release: 26-Feb-2014
$1.6 million to study 'feel-good' brain chemical and hearing
Washington State University Vancouver research scientist Christine Portfors will study how the brain chemical dopamine influences hearing with support from the National Institutes of Health. The work may ultimately lead to better therapies for people with hearing loss and communication problems.
National Institutes of Health

Contact: Christine Portfors
Washington State University

Public Release: 26-Feb-2014
Science Translational Medicine
Beta-catenin alters T cells in lasting and harmful ways
Activation of beta-catenin, the primary mediator of the ubiquitous Wnt signaling pathway, alters the immune system in lasting and harmful ways, causing chronic inflammation in the intestine and colon, eventually leading to cancer. Researchers unravel the mechanism of this transition.
National Institutes of Health, American Cancer Society, Lurie Comprehensive Cancer Center

Contact: John Easton
University of Chicago Medical Center

Public Release: 26-Feb-2014
One gene influences recovery from traumatic brain injury
Researchers report that one change in the sequence of the BDNF gene causes some people to be more impaired by traumatic brain injury than others with comparable wounds.
NIH/National Institute of Neurological Disorders and Stroke, US Army Medical Research and Material Command

Contact: Diana Yates
University of Illinois at Urbana-Champaign

Public Release: 26-Feb-2014
JAMA Psychiatry
IU study ties father's age to higher rates of psychiatric, academic problems in kids
An Indiana University study with the Karolinska Institute found that advancing paternal age can lead to higher rates of psychiatric and academic problems in offspring than previously estimated. Compared to a children born to a 24-year-old father, children born to a 45-year-old father are 3.5 times more likely to have autism, 13 times more likely to have ADHD, twice as likely to have psychotic disorders and 25 times more likely to have bipolar disorder.
NIH/National Institute of Child Health and Human Development, Swedish Research Council

Contact: Brian D'Onofrio
Indiana University

Public Release: 26-Feb-2014
BMC Cancer
Study: Mailing free tests to patients' homes boosts colon cancer screening rates
Colon cancer screening rates increased by nearly 40 percent when free stool tests were mailed to patients' homes, according to results of a pilot study published today in the journal BMC Cancer.
NIH/Health Care Systems Research Collaboratory

Contact: Vincent Staupe
Kaiser Permanente

Public Release: 25-Feb-2014
Cell Host & Microbe
Keck Medicine of USC scientists uncover 2 micro mechanisms that regulate immune system
A Keck Medicine of USC-led team of microbiologists has identified previously unknown interactions between critical proteins in the human immune response system, uncovering two independent regulatory mechanisms that keep the body's immune response in check. Their findings appear in the February 2014 edition of Cell Host & Microbe, the top peer-reviewed scientific journal that focuses on the study of cell-pathogen interaction.
National Institutes of Health

Contact: Alison Trinidad
University of Southern California - Health Sciences

Public Release: 25-Feb-2014
Journal of Clinical Investigation
New clues found to preventing lung transplant rejection
Drugs that broadly suppress the immune system after lung transplantation may inadvertently encourage organ rejection, according to new research at Washington University School of Medicine in St. Louis.
American Association for Thoracic Surgery, National Institutes of Health

Contact: Caroline Arbanas
Washington University School of Medicine

Public Release: 25-Feb-2014
Addictive Behaviors
Research links risky behaviors of gambling and sex
Researchers assessed whether certain adolescent sexual behaviors linked with unintended consequences such as adolescent pregnancy and sexually transmitted infections) are associated with gambling behaviors. They found that almost half their sample -- 49 percent -- had gambled at least once before age 18, and more gamblers than non-gamblers had initiated sexual intercourse by age 18. Approximately one third (35 percent) had intercourse by age 13 and 89 percent had engaged in sexual intercourse by age 18.
NIH/National Institute of Child and Human Development

Contact: Stephanie Berger
Columbia University's Mailman School of Public Health

Public Release: 25-Feb-2014
Journal of Cell Biology
Penn researchers show nuclear stiffness keeps stem cells and cancer cells in place
Adult stem cells and cancer cells have many things in common, including an ability to migrate through tiny gaps in tissue. Both types of cells also experience a trade-off when it comes to this ability; having a flexible nucleus makes migration easier but is worse at protecting the nucleus' DNA compared to a stiffer nucleus. Nuclear proteins that regulate nuclear stiffness are therefore thought to control processes as diverse as tissue repair and tumor growth.
National Institutes of Health, National Science Foundation

Contact: Evan Lerner
University of Pennsylvania

Showing releases 2976-3000 out of 3555.

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