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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 2976-3000 out of 3425.

<< < 115 | 116 | 117 | 118 | 119 | 120 | 121 | 122 | 123 | 124 > >>

Public Release: 19-Sep-2013
Structure
Protein 'motif' crucial to telomerase activity, Wistar researchers say
In an effort to understand and control telomerase activity, researchers at the Wistar Institute have discovered a protein "motif," named TFLY, which is crucial to the function of telomerase. Altering this motif disrupts telomerase function, they found, a fact that they believe will help them in their efforts to identify inhibitors of telomerase with potential cancer therapeutic properties.
NIH/National Institute of General Medical Sciences

Contact: Greg Lester
glester@wistar.org
215-898-3943
The Wistar Institute

Public Release: 19-Sep-2013
Cell Reports
Cutting off all points of escape for melanoma cells
Despite the success of recent melanoma therapies, advanced cancers eventually evolve resistance to drugs. Wistar researchers report on the mechanics by which melanoma can evolve resistance to a powerful combination of drugs -- BRAF and MEK inhibitors. Their studies also uncovered a new potential target for melanoma therapy, a protein called S6K. Additionally, early studies in a laboratory model for melanoma show that a triple combination of drug inhibitors halted the growth of resistant tumors.
NIH/National Cancer Institute, CURE Program of the Pennsylvania Department of Health, and others

Contact: Greg Lester
glester@wistar.org
215-898-3943
The Wistar Institute

Public Release: 19-Sep-2013
Cell Reports
New models of drug-resistant breast cancer hint at better treatments
Breast cancer that spreads to other organs is extremely difficult to treat. Doctors can buy patients time, but a cure remains elusive. Now, researchers at Washington University School of Medicine in St. Louis have shown that human breast tumors transplanted into mice are excellent models of metastatic cancer and could be valuable tools in the search for better treatments.
Susan G. Komen for the Cure, National Human Genome Research Institute, NIH/National Cancer Institute, National Institutes of Health, The Cancer Genome Atlas, Breast Cancer Research Foundation

Contact: Julia Evangelou Strait
straitj@wustl.edu
314-286-0141
Washington University School of Medicine

Public Release: 19-Sep-2013
48th Annual Meeting and Course of the Scoliosis Research Society
New England Journal of Medicine
UI researchers: Bracing is effective in adolescents with idiopathic scoliosis
A multi-center study led by University of Iowa researchers to determine whether wearing back braces would prevent the need for spinal correction surgery in children with adolescent idiopathic scoliosis was cut short when early results were overwhelmingly in favor of bracing.
National Institutes of Health

Contact: Molly Rossiter
molly-rossiter@uiowa.edu
319-356-7124
University of Iowa Health Care

Public Release: 19-Sep-2013
Science
Circadian clock is key to firing up cell's furnace
Each of our cells has an energy furnace, and it is called a mitochondrion. A Northwestern University-led research team now has identified a new mode of timekeeping that involves priming the cell's furnace to properly use stored fuel when we are not eating. The interdisciplinary team has identified the "match" and "flint" responsible for lighting this tiny furnace. And the match is only available when the circadian clock says so, underscoring the importance of the biological timing system to metabolism.
National Institutes of Health, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Endocrine Society

Contact: Megan Fellman
fellman@northwestern.edu
847-491-3115
Northwestern University

Public Release: 19-Sep-2013
PLOS Genetics
Study provides big-picture view of how cancer cells are supported by normal cells in and near tumors
Investigators at CSHL report important progress in research aimed at finding ways to fight cancer by targeting the local environment in which tumors grow and from which they draw sustenance. It's part of the first systematic effort to catalog the repertoire of interactions between cancer cells and their environment.
National Institutes of Health, Susan G. Komen for the Cure, Long Island 2 Day Walk

Contact: Peter Tarr
tarr@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory

Public Release: 18-Sep-2013
University of Maryland researchers studying vaccine to prevent potential bird flu pandemic
Scientists at the University of Maryland School of Medicine's Center for Vaccine Development are part of nationwide vaccine research aimed at protecting adults from a new and virulent strain of avian influenza virus. The virus, called H7N9 influenza virus, emerged in China last spring. The study, sponsored by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, will help prepare for the possibility of a global pandemic.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Bill Seiler
bseiler@umm.edu
410-328-8919
University of Maryland Medical Center

Public Release: 18-Sep-2013
Obesity
New research supports intentional weight loss for older adults
New research from Wake Forest Baptist Medical Center shows that physical activity and weight loss conducted together for older, overweight and obese adults results in improved body composition, translating into lower cardiovascular disease risk and improved mobility.
NIH/National Heart, Lung, and Blood Institute, NIH/National Institute for Aging, National Center for Research Resources

Contact: Bonnie Davis
bdavis@wakehealth.edu
336-716-4977
Wake Forest Baptist Medical Center

Public Release: 18-Sep-2013
Proceedings of the National Academy of Sciences
New role for protein family could provide path to how crop traits are modified
Pioneering new research from a team of Indiana University Bloomington biologists has shown for the first time that a protein which has been long known to be critical for the initiation of protein synthesis in all organisms can also play a role in the regulation of gene expression in some bacteria, and probably land plants as well.
National Science Foundation, Alfred P. Sloan Foundation, National Institutes of Health

Contact: Stephen Chaplin
stjchap@iu.edu
812-856-1896
Indiana University

Public Release: 18-Sep-2013
Angewandte Chemie International Edition
Tiny bottles and melting corks: Temperature regulates new delivery system for drugs and fragrances
Microscopic, bottle-like structures with corks that melt at precisely-controlled temperatures could potentially release drugs inside the body or fragrances onto the skin, according to a recently published study.
NIH/National Cancer Institute, National Institutes of Health, Korean Ministry of Education and Science

Contact: Brett Israel
brett.israel@comm.gatech.edu
404-385-1933
Georgia Institute of Technology

Public Release: 18-Sep-2013
School of Public Health receives $390,000 grant to study alcohol use among youth acquiring HIV
Dr. Monica Swahn, professor in the School of Public Health and associate vice president for research at Georgia State University, has received a two-year, $390,000 grant from the National Institutes of Health to study the role of alcohol marketing and early alcohol use among African youth acquiring HIV.
National Institutes of Health

Contact: Frances Marine
francesmarine@gsu.edu
404-413-1504
Georgia State University

Public Release: 18-Sep-2013
Nature Communications
Scientists develop a new way to identify good fat
When it comes to fat, you want the brown type and not so much of the white variety because brown fat burns energy to keep you warm and metabolically active, while white fat stores excess energy around your waist, causing health problems. Researchers at the University of Texas Health Science Center at Houston Medical School are studying brown fat with a goal of fighting obesity.
National Institutes of Health

Contact: Robert Cahill
Robert.Cahill@uth.tmc.edu
713-500-3030
University of Texas Health Science Center at Houston

Public Release: 18-Sep-2013
ACS Chemical Biology
Researchers demonstrate a new strategy to stop the TB bacterium
Mycobacterium tuberculosis, the bacterium that causes tuberculosis may have an Achilles' heel: it needs a particular enzyme to survive. Inhibiting that enzyme's function, researchers have shown, will kill the bacteria, pointing toward a design strategy for new TB drugs.
National Institutes of Health

Contact: Kevin Stacey
kevin_stacey@brown.edu
401-863-3766
Brown University

Public Release: 18-Sep-2013
NIH prepares by funding new bird flu vaccine studies
Group Health Research Institute scientists are preparing for the potential pandemic spread of a new bird flu strain that caused severe disease in China earlier this year, joining seven other Vaccine and Treatment Evaluation Units funded by the National Institutes of Health to test vaccines to protect against the illness in adults. "Influenza viruses are constantly changing," said Lisa Jackson, M.D., M.P.H., a senior investigator at Group Health Research Institute.
National Institutes of Health

Contact: Rebecca Hughes
hughes.r@ghc.org
206-287-2055
Group Health Research Institute

Public Release: 18-Sep-2013
Nature
Study helps bring genome's 'dark matter' into light
Using technology he helped develop, Vanderbilt University scientist Bryan Venters, Ph.D., has shed new light on the "dark matter" of the genome and has begun to explore a possible new approach to treating cancer.
National Institutes of Health

Contact: Craig Boerner
craig.boerner@vanderbilt.edu
615-322-4747
Vanderbilt University Medical Center

Public Release: 18-Sep-2013
Personal genome, public health
The National Human Genome Research Institute has selected the Johns Hopkins Berman Institute of Bioethics to establish a "Center of Excellence" to study the ethical, legal and social implications of genomic research. The center will be known as GUIDE: Genomic Uses in Infectious Disease & Epidemics.
NIH/National Human Genome Research Institute

Contact: Leah Ramsay
lramsay@jhu.edu
202-642-9640
Johns Hopkins Medicine

Public Release: 18-Sep-2013
Fred Hutch receives $11.3 million NCI grant renewal to lead Pacific Northwest prostate cancer consortium
The National Cancer Institute, a branch of the National Institutes of Health, has awarded an $11.3 million, five-year competitive grant renewal to Fred Hutchinson Cancer Research Center for its continued leadership of a multi-center prostate cancer research consortium, which was first funded in 2002.
NIH/National Cancer Institute

Contact: Kristen Woodward
media@fredhutch.org
206-667-2210
Fred Hutchinson Cancer Research Center

Public Release: 18-Sep-2013
Biomacromolecules
X-ray science taps bug biology to design better materials and reduce pollution
Bug spray, citronella candles, mosquito netting -- most people will do anything they can to stay away from insects during the warmer months. But those creepy crawlers we try so hard to avoid may offer substantial solutions to some of life's problems.
National Science Foundation, US Department of Energy, National Institutes of Health, US Department of Defense

Contact: Tona Kunz
tkunz@anl.gov
630-252-5560
DOE/Argonne National Laboratory

Public Release: 18-Sep-2013
Trial to test prevention of Alzheimer's has begun
The long and hard-fought campaign against Alzheimer's disease has reached a potentially significant milestone: the launch of the first clinical trials to test whether giving new drug treatments before dementia can prevent Alzheimer's.
National Institutes of Health

Contact: Michael C. Purdy
purdym@wustl.edu
314-286-0122
Washington University School of Medicine

Public Release: 18-Sep-2013
Journal of Neuroscience
Studies: Motor control development continues longer than previously believed
Research into fine motor control in children shows that developmental improvements continue much later than previously believed, and aren't isolated to the brain.
National Science Foundation, National Institutes of Health, NIH/National Institute on Disability and Rehabilitation

Contact: Robert Perkins
perkinsr@usc.edu
213-740-9226
University of Southern California

Public Release: 18-Sep-2013
Cell
Interference with cellular recycling leads to cancer growth, chemotherapy resistance
Overactivity of a protein that normally cues cells to divide sabotages the body's natural cellular recycling process, leading to heightened cancer growth and chemotherapy resistance, UT Southwestern researchers have found.
NIH/National Cancer Institute

Contact: Debbie Bolles
debbie.bolles@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center

Public Release: 18-Sep-2013
Clinical Chemistry
Lifestyle, age linked to diabetes-related protein
A large, newly published study that includes more than 13,500 postmenopausal women has yielded the most definitive associations yet between certain lifestyle and demographic factors and levels of a promising early biomarker of type 2 diabetes risk.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Burroughs Wellcome Fund

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 18-Sep-2013
Science of the Total Environment
Higher lead levels may lie just below soil surface
A study of data from hundreds of soil samples taken around six old water tower sites in southern Rhode Island finds that even when lead levels on the surface are low, concentrations can sometimes be greater at depths down to a foot. The findings inform efforts in Rhode Island to assess the effect of lead paint from old water towers on surrounding properties.
NIH/National Institute of Environmental Health Sciences

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 18-Sep-2013
NIH awards grant to Banner Alzheimer's Institute for major prevention study
In collaboration with the National Institutes of Health (NIH), Banner Alzheimer's Institute announces a major prevention trial to evaluate a treatment in cognitively healthy older adults at the highest known genetic risk for developing Alzheimer's disease at older ages. An NIH grant, expected to total $33.2 million, will support this research.
National Institutes of Health

Contact: Kate Enos
kenos@gymr.com
202-745-5071
GYMR

Public Release: 18-Sep-2013
UNLV, Sen. Reid Announce $20 Million NIH grant to support clinical health research
The University of Nevada, Las Vegas was awarded a five-year, $20.3 million grant from the National Institutes of Health to lead a health research network of 13 universities across the Mountain West. The Clinical Translational Research Infrastructure Network will expand the capacity of partner institutions across seven states to put clinical research into practice to address regional health concerns including access to care, cancer, obesity, diabetes, and cardiovascular and infectious diseases.
NIH/National Institute of General Medical Sciences

Contact: Tony Allen
tony.allen@unlv.edu
702-895-0893
University of Nevada, Las Vegas

Showing releases 2976-3000 out of 3425.

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