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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 301-325 out of 3713.

<< < 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 > >>

Public Release: 2-Sep-2015
Nature Communications
Flu study, on hold, yields new vaccine technology
Vaccines to protect against an avian influenza pandemic as well as seasonal flu may be mass produced more quickly and efficiently using technology described today by researchers at the University of Wisconsin-Madison in the journal Nature Communications.
National Institutes of Health, Wisconsin Alumni Research Foundation, Japanese Ministry of Education, Culture, Sports, Science and Technology, Bill and Melinda Gates Foundation

Contact: Yoshihiro Kawaoka
University of Wisconsin-Madison

Public Release: 2-Sep-2015
Science Translational Medicine
Penn researchers report long-term remissions in first personalized cell therapy trial
Eight of 14 patients in the first trial of the University of Pennsylvania's personalized cellular therapy for chronic lymphocytic leukemia (CLL) responded to the therapy, with some complete remissions continuing past four and a half years.
Novartis, Leukemia and Lymphoma Society, National Institutes of Health

Contact: Holly Auer
University of Pennsylvania School of Medicine

Public Release: 1-Sep-2015
ASU team develops quick way to determine bacteria's antibiotic resistance
Bacteria's ability to become resistant to antibiotics is a growing issue in health care: Resistant strains result in prolonged illnesses and higher mortality rates. One way to combat this is to determine bacteria's antibiotic resistance in a given patient, but that often takes days -- and time is crucial in treatment. ASU scientists have developed a technique that can sort antibiotic-resistant from 'susceptible' bacteria, and it happens in a matter of minutes.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Jenny Green
Arizona State University

Public Release: 1-Sep-2015
Translational Research
TGen study identifies potential genes associated with the most common form of liver damage
In a first-of-its-kind exploratory study, the Translational Genomics Research Institute has identified a potential gene associated with the initiation of the most common cause of liver damage. Nonalcoholic fatty liver disease is the most common cause of liver damage. In this study, published in the September edition of Translational Research, TGen scientists sequenced microRNAs from liver biopsies, spelling out their biochemical molecules to identify several potential gene targets associated with NAFLD-related liver damage.
TGen, National Institutes of Health

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 1-Sep-2015
Proceedings of the National Academy of Sciences
Penn and German researchers help identify neural basis of multitasking
By studying networks of activity in the brain's frontal cortex, researchers have shown that the degree to which these networks reconfigure themselves while switching from task to task predicts people's cognitive flexibility.
MacArthur Foundation, Sloan Foundation, Army Research Laboratory, NIH/National Institute of Mental Health, National Science Foundation, German Federal Ministry of Education and Research, Innovative Medicines Initiative Joint Undertaking

Contact: Evan Lerner
University of Pennsylvania

Public Release: 1-Sep-2015
Yeast study yields insights into cell-division cycle
Studies using yeast genetics have provided new, fundamental insights into the cell-division cycle, researchers at the University of Michigan Life Sciences Institute report.
National Institutes of Health

Contact: Ian Demsky
University of Michigan

Public Release: 1-Sep-2015
UC San Diego scientists investigate global hemorrhagic fever bacterial disease
An international research team, headed by Joseph Vinetz, M.D., professor of medicine at University of California, San Diego School of Medicine and director of the UC San Diego Center for Tropical Medicine and Travelers Health, has been awarded a five-year, $1.89 million cooperative agreement to carry out transnational research studies of leptospirosis, an infectious and sometimes fatal bacterial disease endemic in much of the world.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Scott LaFee
University of California - San Diego

Public Release: 1-Sep-2015
Alzheimer's & Dementia
Clinical trial is 1st to study impact of cognitive impairment assessment in primary care
The first clinical trial to investigate the impact of primary care physicians testing their patients for cognitive impairment found that doctors given information on a patient's cognitive status provided more care focused on cognition but that care had no impact on the overall rate of the patient's cognitive decline.
NIH/National Institute on Aging

Contact: Cindy Fox Aisen
Indiana University

Public Release: 1-Sep-2015
Molecular Psychiatry
Gene may predict severity of post-traumatic stress disorder
A gene linked in previous research, appears to predict more severe post-traumatic stress disorder (PTSD) symptoms as well as a thinner cortex in regions of the brain critical for regulating strong emotions and coping with stressful experiences. This study is believed to be the first to show that the spindle and kinetochore-associated complex subunit 2 gene may play a role in the development of PTSD.
NIH/National Institute of Mental Health, Translational Research Center for TBI and Stress Disorders, VA Rehabilitation Research and Development Traumatic Brain

Contact: Kristen Perfetuo
Boston University Medical Center

Public Release: 1-Sep-2015
Metabolic Engineering
'Bacterial litmus test' provides inexpensive measurement of micronutrients
A bacterium engineered to produce different pigments in response to varying levels of a micronutrient in blood samples could give health officials an inexpensive way to detect nutritional deficiencies in resource-limited areas of the world. This 'bacterial litmus test,' which currently measures levels of zinc, would require no electrical equipment and make results visible as simple color changes.
Bill & Melinda Gates Foundation, National Science Foundation, National Institutes of Health

Contact: John Toon
Georgia Institute of Technology

Public Release: 1-Sep-2015
Diabetic retinopathy screening for children with type 1 diabetes should start later
Researchers are recommending that most children with type 1 diabetes delay annual diabetic retinopathy screenings until age 15, or five years after their diabetes diagnosis, whichever occurs later.
National Institutes of Health

Contact: Maya Chupkov
American Academy of Ophthalmology

Public Release: 1-Sep-2015
Daily marijuana use among US college students highest since 1980
Daily marijuana use among the nation's college students is on the rise, surpassing daily cigarette smoking for the first time in 2014.
NIH/National Institute on Drug Abuse

Contact: Jared Wadley
University of Michigan

Public Release: 1-Sep-2015
Cancer Research
Modified CAR T cells can preferentially target cancer cells and spare normal cells
Engineering chimeric antigen receptor (CAR) T cells to lower their affinity for the protein epithelial growth factor receptor (EGFR) made the cells preferentially recognize and eliminate tumor cells that have high amounts of EGFR while sparing normal cells that have lower amounts of the protein, according to a preclinical study.
National Institutes of Health

Contact: Julia Gunther
American Association for Cancer Research

Public Release: 1-Sep-2015
Cancer Research
Newly engineered CAR T cells can better discriminate between cancer and normal cells
A new development in engineering chimeric antigen receptor (CAR) T cells, called affinity tuning, can make the CAR T cells spare normal cells and better recognize and attack cancer cells, which may help lower the toxicity associated with this type of immunotherapy when used against solid tumors, according to a preclinical study.
National Institutes of Health

Contact: Julia Gunther
American Association for Cancer Research

Public Release: 1-Sep-2015
Neurobiology of Disease
Mass. General study identifies another way urate may protect against Parkinson's disease
A study from members of the research team investigating whether increasing blood levels of the antioxidant urate can slow the progression of Parkinson's disease has found that the neuroprotective effects of urate extend beyond its own antioxidant properties. An NIH-funded phase 3 trial of a urate-elevating drug, led by the senior author of the current study, will begin enrolling patients next year.
US Department of Defense, NIH/National Institute of Neurological Disorders and Stroke

Contact: Terri Ogan
Massachusetts General Hospital

Public Release: 1-Sep-2015
Genetic landscape can impact treatment for children with rare, aggressive cancer
For children with rare, aggressive and advanced cancer, precision medicine may help doctors determine their best treatment options, a new study finds. Using information from a patient's entire genome helped suggest personalized treatment options for nearly half of children with cancer, and led to specific treatment changes in a quarter of these patients.
National Institutes of Health, Prostate Cancer Foundation, Good Charity Inc.

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 31-Aug-2015
Psychiatric Services
Organized self-management support eases chronic depression
In a randomized trial, people with chronic or recurrent depression benefited from self-management support that included regular outreach care management and a self-care group with a combined behavioral and recovery-oriented approach. Over 18 months, patients improved significantly in all four measured outcomes. Compared to patients in usual care at Group Health and Swedish, they had less severe symptoms and less likelihood of having major depression, higher recovery scores, and higher likelihood of being much improved.
NIH/National Institute of Mental Health

Contact: Rebecca Hughes
Group Health Research Institute

Public Release: 31-Aug-2015
Northwestern, partners launch AIDS research center to stop HIV
A new $6.25 million NIH grant will create a Third Coast Coast Center for AIDS Research to help investigators from Northwestern University, the University of Chicago and others across the city of Chicago work together to slow and stop HIV. HIV infections rise 5 percent each year in young gay men.
National Institutes of Health

Contact: Marla Paul
Northwestern University

Public Release: 31-Aug-2015
Research in mice shows potential value of antidepressant in some stroke victims
Working with mice, researchers at Johns Hopkins have added to evidence that a commonly prescribed antidepressant called fluoxetine helps stroke victims improve movement and coordination, and possibly why.
Johns Hopkins, NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute of Child Health and Human Development, James S. McDonnell Foundation, National Science Foundation

Contact: Shawna Williams
Johns Hopkins Medicine

Public Release: 31-Aug-2015
New UC Davis environmental research center links science with advocacy
A cross-disciplinary center focused on identifying connections between environmental toxins and disease has been established at UC Davis Health System with the ultimate goal of developing preventions and policies that protect communities from unhealthy exposures.
NIH/National Institute of Environmental Health Sciences

Contact: Karen Finney
University of California - Davis Health System

Public Release: 31-Aug-2015
Using nanotechnology to fight cancer
Northwestern University, a leader in cancer nanotechnology research, has received a five-year, $11.7 million grant from the National Cancer Institute to use nanotechnology to develop next-generation cancer treatments. The Northwestern University Center for Cancer Nanotechnology Excellence will use nucleic-acid-based nanoconstructs called Spherical Nucleic Acids to access intracellular environments, discover new aspects of cancer biology and create effective cancer treatment options. A focus will be on helping those suffering from glioblastoma multiforme and prostate cancer.
NIH/National Cancer Institute

Contact: Megan Fellman
Northwestern University

Public Release: 31-Aug-2015
$13 million grant to continue funding for new social science research methods
The Methodology Center at Penn State has received a $13 million grant from the National Institute on Drug Abuse to support both ongoing and new research for the next five years that could lead to health apps for smartphones and more accurate genetic research.
NIH/National Institute on Drug Abuse

Contact: Victoria M. Indivero
Penn State

Public Release: 31-Aug-2015
Nature Medicine
Infection with multiple HIV-1 variants leads to poorer clinical outcomes
HIV-1 infection with multiple founder variants points to poorer clinical outcomes than infection with a single variant, according to a paper published today in Nature Medicine. In the study researchers analyzed large sample sets from two important HIV vaccine efficacy trials -- the Step HIV vaccine clinical trial (HVTN 502) and RV144, the landmark vaccine clinical trial conducted in Thailand -- to evaluate whether genetic characteristics of the founder viral populations could influence markers of clinical outcomes.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Lisa Reilly
The U.S. Military HIV Research Program (MHRP)

Public Release: 31-Aug-2015
NCI awards SPORE grant to multiple myeloma research team from Mayo Clinic Cancer Center
A team of Mayo Clinic Cancer Center scientists has been awarded a Specialized Program of Research Excellence (SPORE) grant in multiple myeloma from the National Cancer Institute. The Mayo Clinic Cancer Center is one of only three cancer centers to receive a SPORE grant for multiple myeloma cancer research.
NIH/National Cancer Institute

Contact: Joe Dangor
Mayo Clinic

Public Release: 31-Aug-2015
Nature Methods
DNA-guided 3-D printing of human tissue is unveiled
UCSF researchers developed a technique to build tiny models of human tissues, called organoids, more precisely than ever before using a process that turns human cells into a biological equivalent of LEGO bricks. These mini-tissues in a dish can be used to study how particular structural features of tissue affect normal growth or go awry in cancer; for therapeutic drug screening and to help teach researchers how to grow whole human organs.
The Department of Defense Breast Cancer Research Program, the National Institutes of Health, the Sidney Kimmel Foundation, the UCSF Program in Breakthrough Biomedical Research

Contact: Nicholas Weiler
University of California - San Francisco

Showing releases 301-325 out of 3713.

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