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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 301-325 out of 3399.

<< < 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 > >>

Public Release: 23-Mar-2014
Nature Chemical Biology
Shifting evolution into reverse promises cheaper, greener way to make new drugs
A proof-of-concept experiment has shown that, by shifting evolution into reverse, it may be possible to use 'green chemistry' to make a number of costly synthetic drugs as easily and cheaply as brewing beer.
National Science Foundation, National Institutes of Health, US Department of Energy

Contact: David Salisbury
david.salisbury@vanderbilt.edu
615-343-6803
Vanderbilt University

Public Release: 23-Mar-2014
Nature Materials
MIT engineers design 'living materials'
Hybrid materials combine bacterial cells with nonliving elements that can conduct electricity or emit light.
Office of Naval Research, US Army Research Office, National Science Foundation, Hertz Foundation, US Department of Defense, National Institutes of Health, Presidential Early Career Awrd for Scientists & Engineers

Contact: Sarah McDonnell
s_mcd@mit.edu
617-253-8923
Massachusetts Institute of Technology

Public Release: 23-Mar-2014
Nature Structural & Molecular Biology
Mass. General study identifies path to safer drugs for heart disease, cancer
Massachusetts General Hospital investigators may have found a way to solve a problem that has plagued a group of drugs called ligand-mimicking integrin inhibitors, which have the potential to treat conditions ranging from heart attacks to cancer metastasis.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital

Public Release: 21-Mar-2014
Journal of Clinical Oncology
Keck Medicine of USC research may point to better predictor of prostate cancer survival
New research by USC Norris Comprehensive Cancer Center scientists demonstrates that measuring circulating tumor cells -- the cells that spread cancer through the body -- may be a better predictor of patient survival than the prostate-specific antigen.
NIH/National Cancer Institute, Hope Foundation

Contact: Leslie Ridgeway
lridgewa@usc.edu
323-442-2823
University of Southern California - Health Sciences

Public Release: 21-Mar-2014
With a few finger taps, draw genetic pedigrees at point of care with new app
Long used in genetic medicine, pedigrees are diagrams that show how inherited diseases may recur in a particular family. A new app adds a digital spin, letting clinicians create pedigrees with a few finger taps during a patient encounter.
NIH/National Human Genome Research Institute

Contact: John Ascenzi
ascenzi@email.chop.edu
267-426-6055
Children's Hospital of Philadelphia

Public Release: 21-Mar-2014
Journal of Dental Research
Gene expression signature reveals new way to classify gum disease
Researchers have devised a new system for classifying periodontal disease based on the genetic signature of affected tissue, rather than on clinical signs and symptoms. The new classification system, the first of its kind, may allow for earlier detection and more individualized treatment of severe periodontitis, before loss of teeth and supportive bone occurs. The findings were published recently in the online edition of the Journal of Dental Research.
NIH/National Institute of Dental and Craniofacial Research, National Institutes of Health, Colgate-Palmolive

Contact: Karin Eskenazi
ket2116@columbia.edu
212-342-0508
Columbia University Medical Center

Public Release: 20-Mar-2014
Stem Cell Reports
Stem cell study finds source of earliest blood cells during development
In a study published April 8 in Stem Cell Reports, Matthew Inlay of the Sue & Bill Gross Stem Cell Research Center and Stanford University colleagues created novel cell assays that identified the earliest arising HSC precursors based on their ability to generate all major blood cell types (red blood cells, platelets and immune cells).
National Institutes of Health

Contact: Matthew Inlay
minlay@uci.edu
949-824-8226
University of California - Irvine

Public Release: 20-Mar-2014
Cell Reports
Surprising new way to kill cancer cells
Scientists have demonstrated that cancer cells -- and not normal cells -- can be killed by eliminating either the FAS receptor, also known as CD95, or its binding component, CD95 ligand. The discovery seems counterintuitive because CD95 has previously been defined as a tumor suppressor, scientists said.
NIH/National Cancer Institute

Contact: Marla Paul
marla-paul@northwestern.edu
312-503-8928
Northwestern University

Public Release: 20-Mar-2014
Einstein helps establish $28 million consortium to find ebola treatment
Albert Einstein College of Medicine helps establish new $28 million consortium to find antibody treatments for Ebola and other viruses.
National Institutes of Health

Contact: Deirdre Branley
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine

Public Release: 20-Mar-2014
Journal of Clinical Investigation
Genome-wide association studies mislead on cardiac arrhythmia risk gene
Although genome-wide association studies have linked DNA variants in the gene SCN10A with increased risk for cardiac arrhythmia, efforts to determine its role have been unproductive. Now, scientists have discovered that these SCN10A variants regulate a different gene, SCN5A, which appears to be the primary gene responsible for cardiac arrhythmia risk. The SCN10A gene itself plays only a minimal role in the heart, according to the study, published in the Journal of Clinical Investigation.
National Institutes of Health

Contact: Kevin Jiang
kevin.jiang@uchospitals.edu
773-795-5227
University of Chicago Medical Center

Public Release: 20-Mar-2014
Can a treadmill help seniors avoid falls?
Clive Pai, professor of physical therapy at the University of Illinois at Chicago will use a five-year, $1 million grant from the National Institute of Aging to develop a computerized treadmill program that could be used in physical therapy offices to prevent falls and fall-related injuries in older adults.
NIH/National Institute on Aging

Contact: Jeanne Galatzer-Levy
jgala@uic.edu
312-996-1583
University of Illinois at Chicago

Public Release: 20-Mar-2014
NIH grants up to $28 million to group led by Scripps Research for work on ebola treatment
The National Institutes of Health has awarded a five-year grant of up to $28 million to establish a new center for excellence to find an antibody 'cocktail' to fight the deadly Ebola virus. The project, which involves researchers from 15 institutions, will be led by Erica Ollmann Saphire, professor at the Scripps Research Institute.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 20-Mar-2014
Cell Stem Cell
Proteins that control energy use necessary to form stem cells
Two proteins that control how cells metabolize glucose play a key role in the formation of human stem cells. Studies suggest these proteins which also play a role in the process that transforms normal cells into cancer stem cells, might also be targets for new cancer therapies.
American Heart Association, Tietze Award, National Institutes of Health

Contact: Kim Blakeley
krb13@uw.edu
206-685-1323
University of Washington - Health Sciences/UW News, Community Relations & Marketing

Public Release: 20-Mar-2014
Journal of Clinical Investigation
Inhibition of CDK4 might promote lymphoma development and progression
Anticancer agents that inhibit tumor growth by targeting a cell-cycle regulatory protein called CDK4 might actually promote the development and progression of certain B-cell lymphomas. The research suggests that CDK4 inhibitors, which are now in clinical testing, should be used cautiously, particularly in patients with B-cell lymphomas. The findings raise the possibility that these inhibitors work through off-target effects and require further investigation.
NIH/National Cancer Institute

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 20-Mar-2014
Neuroscientist investigates how the brain repairs itself after a stroke
A neuroscientist at the Virginia-Maryland Regional College of Veterinary Medicine hopes that a better understanding of how the brain restores blood flow to damaged tissue following a stroke will offer new treatment clues for a leading cause of death in the United States.
National Institutes of Health

Contact: Sherrie R Whaley
srwhaley@vt.edu
540-231-7911
Virginia Tech

Public Release: 20-Mar-2014
Cancer Cell
Study reveals a major mechanism driving kidney cancer progression
The shortage of oxygen, or hypoxia, created when rapidly multiplying kidney cancer cells outgrow their local blood supply can accelerate tumor growth by causing a nuclear protein called SPOP -- which normally suppresses tumor growth -- to move out of the nucleus to the cytoplasm, where it has the opposite effect, promoting rapid proliferation. This cytoplasmic accumulation of SPOP is sufficient to convey tumorigenic properties onto otherwise non-tumorigenic cells.
National Institutes of Health, Beijing Science Foundation, Keck Foundation, Chicago Community Trust, Chicago Biomedical Consortium

Contact: John Easton
john.easton@uchospitals.edu
773-795-5225
University of Chicago Medical Center

Public Release: 20-Mar-2014
Psychiatric Services
Lifestyle interventions can prevent major depression in adults with mild symptoms
Discussions with a dietary coach to learn about healthy eating were as effective as meeting with a counselor for problem-solving or 'talk' therapy in preventing major depression among older black and white adults with mild symptoms of the mood disorder, according to researchers at the University of Pittsburgh and the University of Maryland. Their findings were published online recently in Psychiatric Services.
National Institutes of Health, NIH/National Institute of Mental Health, NIH/National Institute on Minority Health and Health Disparities, University of Pittsburgh Medical Center Endowment in Geriatric Psychiatry, Commonwealth of Pennsylvania

Contact: Anita Srikameswaran
SrikamAV@upmc.edu
412-578-9193
University of Pittsburgh Schools of the Health Sciences

Public Release: 20-Mar-2014
Blood
Low levels of oxygen, nitric oxide worsen sickle cell disease
Low levels of both oxygen and the powerful blood vessel dilator nitric oxide appear to have an unfortunate synergy for patients with sickle cell disease, researchers report.
National Institutes of Health

Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University

Public Release: 20-Mar-2014
$1.5 million grant helps turn chemical weapon into medical marvel
A Washington State University chemist has received a $1.5 million grant from the National Institutes of Health to look into using a highly toxic compound that can prevent the tissue damage of a heart attack by putting the patient into a form of hibernation.
National Institutes of Health

Contact: Ming Xian
mxian@wsu.edu
509-335-6073
Washington State University

Public Release: 20-Mar-2014
Gastroenterology
Colonoscopy isn't perfect: About 6 percent of colorectal cancers are missed
About 6 percent of colorectal cancers are diagnosed within three to five years after the patient receives a clean colonoscopy report, according to a population-based study by researchers from Huntsman Cancer Institute at the University of Utah.
Huntsman Cancer Institute, NIH/National Cancer Institute

Contact: Linda Aagard
801-587-7639
University of Utah Health Sciences

Public Release: 20-Mar-2014
Stroke
Bedside optical monitoring of cerebral blood flow promising for individualized stroke care
Using a University of Pennsylvania-designed device to noninvasively and continuously monitor cerebral blood flow in acute stroke patients, researchers from Penn Medicine and the Department of Physics & Astronomy in Penn Arts and Sciences are now learning how head of bed positioning affects blood flow reaching the brain.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute of Child Health and Human Development, NIH/National Institute of Biomedical Imaging and Bioengineering, Sao Paolo Research Foundation, Fundacio Cellex

Contact: Kim Menard
kim.menard@uphs.upenn.edu
215-662-6183
University of Pennsylvania School of Medicine

Public Release: 20-Mar-2014
American Journal of Human Genetics
New tool pinpoints genetic sources of disease
Many diseases have their origins in either the genome or in reversible chemical changes to DNA known as the epigenome. Now, results of a new study from Johns Hopkins scientists show a connection between these two 'maps.' The findings, reported March 20 in the American Journal of Human Genetics, could help disease trackers find patterns that offer clues to the causes of and possible treatments for complex genetic conditions, including many cancers and metabolic disorders.
NIH/National Human Genome Research Institute, NIH/National Institute on Aging, Swedish AFA Insurance, Swedish Foundation for Strategic Research, European Research Council

Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine

Public Release: 20-Mar-2014
Science
Sniff study suggests humans can distinguish more than 1 trillion scents
Based on the sensitivity of these people's noses and brains, Rockefeller researchers calculate that the human sense of smell is far more refined than previously believed. While individual volunteers' performance varied, on average people can tell the difference between complex mixtures of odors even when they contain many of the same components.
NIH/National Center for Advancing Translational Sciences

Contact: Zach Veilleux
zveilleux@rockefeller.edu
212-327-8982
Rockefeller University

Public Release: 20-Mar-2014
Clinical Journal of the American Society of Nephrology
Initiation of dialysis for acute kidney injury potentially dangerous for frail patients
The decision to initiate dialysis for acute kidney injury varies depending on different patient factors and there is a lack of robust evidence as to which patients are likely to benefit most and why. A new study from researchers at the Perelman School of Medicine at the University of Pennsylvania has shown that for patients with lower creatinine concentration levels -- a sign of reduced muscle mass and weakness -- initiation of dialysis could actually be detrimental.
NIH/National Institute of Diabetes and Digestive and Kidney Disease

Contact: Jessica Mikulski
jessica.mikulski@uphs.upenn.edu
215-349-8369
University of Pennsylvania School of Medicine

Public Release: 20-Mar-2014
Science
Cellular 'counting' of rhythmic signals synchronizes changes in cell fate
Johns Hopkins biologists have discovered that when biological signals hit cells in rhythmic waves, the magnitude of the cells' response can depend on the number of signaling cycles -- not their strength or duration. Because such so-called 'oscillating signaling cycles' are common in many biological systems, the scientists expect their findings in single-celled organisms to help explain the molecular workings of phenomena such as tissue and organ formation and fundamental forms of learning.
NIH/National Institute of General Medical Sciences, NIH/Eunice Kennedy Shriver National Institute of Child Health, Helen Hay Whitney Foundation, Japan Society for the Promotion of Science, RIKEN

Contact: Catherine Kolf
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine

Showing releases 301-325 out of 3399.

<< < 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 > >>

     
   

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