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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 301-325 out of 3768.

<< < 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 > >>

Public Release: 28-Jul-2015
Journal of General Internal Medicine
Big data gives new insight into blood pressure reduction role of commonly prescribed drug
A new big data study conducted by researchers from the Regenstrief Institute and Indiana University has found that a drug commonly prescribed to conserve potassium in the blood also significantly lowers blood pressure when taken in conjunction with a diuretic frequently prescribed to patients with hypertension. The combination of the two drugs, both available as generics, has been shown to consistently amplify the blood pressure reduction in patients with or without the presence of other antihypertensive agents such as ACE inhibitors and calcium channel blockers.
NIH/National Heart, Lung, and Blood Institute

Contact: Cindy Fox Aisen
Indiana University

Public Release: 28-Jul-2015
Journal of the American Chemical Society
New chemistry makes strong bonds weak
Researchers at Princeton have developed a new chemical reaction that breaks the strongest bond in a molecule instead of the weakest, completely reversing the norm for reactions in which bonds are evenly split to form reactive intermediates. Published on July 13 in the Journal of the American Chemical Society, the non-conventional reaction is a proof of concept that will allow chemists to access compounds that are normally off-limits to this pathway.
National Institutes of Health

Contact: Tien Nguyen
Princeton University

Public Release: 28-Jul-2015
Journal of Experimental Medicine
Penn Vet study shows immune cells in the skin remember and defend against parasites
For the first time, researchers from the University of Pennsylvania found resident T cells in a tissue in response to a parasite infection. The finding could help inform efforts to develop an effective vaccine for leishmaniasis, as well as other diseases such as tuberculosis and leprosy.
National Institutes of Health

Contact: Katherine Unger Baillie
University of Pennsylvania

Public Release: 28-Jul-2015
American Economic Review
Firms 'underinvest' in long-term cancer research
Pharmaceutical firms 'underinvest' in long-term research to develop new cancer-fighting drugs due to the greater time and cost required to conduct such research, according to a newly published study co-authored by MIT economists.
NIH/National Institute on Aging, National Science Foundation

Contact: Abby Abazorius
Massachusetts Institute of Technology

Public Release: 28-Jul-2015
CA: A Cancer Journal for Clinicians
Cancer healthcare disparities exist in the LGBTQ community, say Moffitt researchers
Moffitt Cancer Center researchers published one of the first articles that describe the current knowledge about cancers that may disproportionately affect the LGBTQ community, and also offered suggestions for improving their healthcare.
NIH/National Cancer Institute

Contact: Kim Polacek
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 28-Jul-2015
A marked improvement in health and healthcare for Medicare patients
In a 15-year study of older Medicare patients, Yale School of Medicine researchers saw an estimated 20 percent drop in mortality, about 30 percent fewer hospitalizations, and 40 percent reduction in deaths after hospitalization.
NIH/National Heart, Lung, and Blood Institute

Contact: Karen N. Peart
Yale University

Public Release: 28-Jul-2015
Annals of Behavioral Medicine
Link between mood, pain in rheumatoid arthritis patients
Depressive symptoms and mood in the moment may predict momentary pain among rheumatoid arthritis patients, according to Penn State researchers.
NIH/National Heart, Lung, and Blood Institute, National Science Foundation

Contact: A'ndrea Elyse Messer
Penn State

Public Release: 28-Jul-2015
Journal of Speech, Language, and Hearing Research
Movement tracking technology sheds light on different speech disorders in children
Facial motion capture -- the same technology used to develop realistic computer graphics in video games and movies -- has been used to identify differences between children with childhood apraxia of speech and those with other types of speech disorders, finds a new study by NYU's Steinhardt School of Culture, Education, and Human Development.
NIH/National Institute on Deafness and Other Communication Disorders

Contact: Rachel Harrison
New York University

Public Release: 28-Jul-2015
Journal of National Cancer Institute
Race & institutional factors play an important role in pharmacogenomic trial participation
Moffitt Cancer Center researchers have published a study in the Journal of the National Cancer Institute that analyzed the participation rate of patients in pharmacogenomic trials.
NIH/National Cancer Institute, Cancer and Leukemia Group B

Contact: Kim Polacek
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 28-Jul-2015
Nature Communications
Pitt study: Ancient proteins involved in DNA repair could shed light on tumor development
By studying yeast used in beer- and bread-making, researchers at the University of Pittsburgh School of Medicine have uncovered the mechanism by which ancient proteins repair DNA damage and how their dysfunction could lead to the development of tumors. The findings, published online today in Nature Communications, could lead to new ways to tailor cancer therapies.
National Institutes of Health

Contact: Anita Srikameswaran
University of Pittsburgh Schools of the Health Sciences

Public Release: 28-Jul-2015
Nature Materials
Technology helps personalized medicine, enabling epigenomic analysis with a mere 100 cells
A new technology, improving the efficiency of the studies in epigenomics, is the subject of a Nature Methods journal article by Chang Lu and Zhenning Cao of Virginia Tech and Kai Tan, Changya Chen and Bing He of the University of Iowa. The research was funded by the National Institutes of Health, following a seed grant from Virginia Tech's Institute for Critical Technology and Applied Science.
National Institutes of Health, Virginia Tech Institute for Critical Technology and Applied Science

Contact: Lynn Nystrom
Virginia Tech

Public Release: 28-Jul-2015
Journal of Neuroscience
Research grasps how the brain plans gripping motion
A new study significantly advances neuroscientists' understanding of how a region of the brain formulates plans for the hand to grip an object. The findings could lead to direct application to improving brain-computer interface control over robotic arms and hands.
US Department of Veterans Affairs, National Institutes of Health, Defense Advanced Research Projects Agency, Katie Samson Foundation

Contact: David Orenstein
Brown University

Public Release: 28-Jul-2015
Specific cardiovascular risk factors may predict Alzheimer's disease
Specific cardiovascular risk factors, such as alcohol consumption, smoking, obesity and diabetes, are associated with smaller regional brain volumes that may be early indicators of Alzheimer's disease and dementia according to a study.
National Institutes of Health

Contact: Linda Brooks
Radiological Society of North America

Public Release: 27-Jul-2015
American Journal of Respiratory Cell and Molecular Biology
Researchers create promising new mouse model for lung injury repair
Researchers at Children's Hospital Los Angeles and The Saban Research Institute of CHLA have created a dynamic functional mouse model for lung injury repair, a tool that will help scientists explain the origins of lung disease and provide a system by which new therapies can be identified and tested. Their findings have been published online by the American Journal of Respiratory Cell and Molecular Biology.
National Institutes of Health, Pasadena Guild, Garland Foundation, California Institute of Regenerative Medicine

Contact: Jennifer Marcus
Children's Hospital Los Angeles

Public Release: 27-Jul-2015
NIH helps UC San Diego researchers repurpose Sanofi pain drug for tropical disease
The National Center for Advancing Translational Sciences, part of the National Institutes of Health, has awarded James McKerrow, M.D., Ph.D., dean of the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences, with a 2015 New Therapeutic Uses Award.
NIH/National Center for Advancing Translational Sciences

Contact: Heather Buschman
University of California - San Diego

Public Release: 27-Jul-2015
Journal of the American College of Cardiology
One in 4 patients with defibrillators experiences boost in heart function over time
A Johns Hopkins-led study of outcomes among 1,200 people with implanted defibrillators -- devices intended to prevent sudden cardiac death from abnormal heart rhythms -- shows that within a few years of implantation, one in four experienced improvements in heart function substantial enough to put them over the clinical threshold that qualified them to get a defibrillator in the first place.
National Institutes of Health, Donald W. Reynolds Foundation

Contact: Ekaterina Pesheva
Johns Hopkins Medicine

Public Release: 27-Jul-2015
Cell Reports
In lab tests, new therapy slows spread of deadly brain tumor cells
The rapid spread of a common and deadly brain tumor has been slowed down significantly in a mouse model by cutting off the way some cancer cells communicate, according to a team of researchers that includes UF Health faculty.
American Cancer Society, National Institutes of Health, Sontag Foundation, Lerner Research Institute, Florida Center for Brain Tumor Research

Contact: Doug Bennett
University of Florida

Public Release: 27-Jul-2015
$4.8 million NIH study will teach an old drug to maintain its tricks
With the help of a nearly $4.9 million, 5-year grant from the National Institute for Allergy and Infectious Diseases of the National Institutes of Health, Wayne State University School of Medicine researchers are leading a landmark multi-center, international study that will provide essential information to clinicians for use of polymoxin B in critically ill patients where no other treatments will work.
NIH/National Institute for Allergy and Infectious Diseases

Contact: Julie O'Connor
Wayne State University - Office of the Vice President for Research

Public Release: 27-Jul-2015
Study will explore taste changes related to obesity, gastric bypass surgery
Currently, one of the most effective surgical methods for treating obesity is the Roux-en-Y gastric bypass surgery, which limits the amount of food and drink that can be ingested at one time and the amount of calories and nutrients absorbed through the intestinal tract. An unintended side effect of RYGB is that it reduces the patient's taste for sweet and fatty foods -- but there is no scientific explanation for why these taste changes occur.
National Institutes of Health

Contact: Kat Gilmore
University of Georgia

Public Release: 27-Jul-2015
Developmental Neuropsychology
Babies' brains show that social skills linked to second language learning
Babies learn language best by interacting with people rather than passively through a video or audio recording. But it's been unclear what aspects of social interactions make them so important for learning. New findings by researchers at the Institute for Learning & Brain Sciences at the University of Washington demonstrate for the first time that an early social behavior called gaze shifting is linked to infants' ability to learn new language sounds.
National Science Foundation, National Institutes of Health

Contact: Molly McElroy
University of Washington

Public Release: 27-Jul-2015
Nature Genetics
Yale study identifies 'major player' in skin cancer genes
A multidisciplinary team at Yale, led by Yale Cancer Center members, has defined a subgroup of genetic mutations that are present in a significant number of melanoma skin cancer cases. Their findings shed light on an important mutation in this deadly disease, and may lead to more targeted anti-cancer therapies.
Yale SPORE in Skin Cancer, NIH/National Cancer Institute, US National Institutes of Health, Melanoma Research Alliance, Gilead Sciences, Inc., Howard Hughes Medical Institute

Contact: Ziba Kashef
Yale University

Public Release: 27-Jul-2015
Tissue Engineering
Scientists' silk structure is secret to process of regenerating salivary cells
A research team led by Chih-Ko Yeh, B.D.S., Ph.D., from The University of Texas Health Science Center at San Antonio, is the first to use silk fibers as a framework to grow stem cells into salivary gland cells. The new process could provide relief for millions of individuals with dry mouth, including patients with Sjögren's syndrome, survivors of head and neck cancer, and those who take drugs with a side effect that limits saliva production.
NIH/National Institute of Dental and Craniofacial Research, Veterans Administration

Contact: Rosanne Fohn
University of Texas Health Science Center at San Antonio

Public Release: 27-Jul-2015
Proceedings of the National Academy of Sciences
Narrowing in on pituitary tumors
In a new study published in the Proceedings of the National Academy of Sciences on July 27, investigators from Brigham and Women's Hospital present a new technique that could help surgeons more precisely define the locations of pituitary tumors in near real-time.
National Institutes of Health, US Army Medical Research/CIMIT, National Center for Image Guided Therapy

Contact: Haley Bridger
Brigham and Women's Hospital

Public Release: 27-Jul-2015
Scientists win $1.5 million to study new strategies for Parkinson's disease and other disorders
Scientists from the Florida campus of The Scripps Research Institute have been awarded nearly $1.5 million from the National Institute of General Medical Sciences to explore the therapeutic potential of a class of proteins that play essential roles in the regulation and maintenance of human health.
NIH/National Institute of General Medical Sciences

Contact: Eric Sauter
Scripps Research Institute

Public Release: 27-Jul-2015
Proceedings of the National Academy of Sciences
Gene therapy may improve survival of patients with recurrent ovarian cancer
Use of gene therapy to deliver a protein that suppresses the development of female reproductive organs may improve the survival of patients with ovarian cancer that has recurred after chemotherapy, which happens 70 percent of the time and is invariably fatal.
Ovarian Cancer Research Fund, Sudna Gar Foundation, US Department of Defense, National Institutes of Health

Contact: Katie Marquedant
Massachusetts General Hospital

Showing releases 301-325 out of 3768.

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