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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 3001-3025 out of 3753.

<< < 116 | 117 | 118 | 119 | 120 | 121 | 122 | 123 | 124 | 125 > >>

Public Release: 11-Nov-2014
PLOS Medicine
Genes identify transplant rejection
Acute rejection after kidney transplantation occurs in about 15-20 percent of patients despite immunosuppressive therapy. In the Assessment of Acute Rejection in Renal Transplantation study published this week in PLOS Medicine, Minnie Sarwal (Department of Surgery, University of California San Francisco, San Francisco, California, United States of America) and colleagues developed a 17-gene set to analyze patients' peripheral blood samples to determine which patients were at risk of acute rejection of their kidney transplants.
NIH/National Institute of Allergy and Infectious Diseases , Mexican Federal Funds for Research, NIH, Spanish national public grant, European Commission Grant within the BIODRIM Consortium

Contact: Maya Sandler
medicinepress@plos.org
PLOS

Public Release: 10-Nov-2014
Cell Reports
The brain's 'inner GPS' gets dismantled
Imagine being able to recognize your car as your own but never being able to remember where you parked it. Researchers at University of California, San Diego School of Medicine have induced this all-too-common human experience -- or a close version of it -- permanently in rats and from what is observed perhaps derive clues about why strokes and Alzheimer's disease can destroy a person's sense of direction.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute of Mental Health, Department of Veterans Affairs

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 10-Nov-2014
Journal of Clinical Oncology
Smoking associated with elevated risk of developing a second smoking-related cancer
Results of a federally-funded pooled analysis of five prospective cohort studies indicate that cigarette smoking prior to the first diagnosis of lung (stage I), bladder, kidney or head and neck cancer increases risk of developing a second smoking-associated cancer. This is the largest study to date exploring risk of second cancers among current smokers.
NIH/National Cancer Institute

Contact: Kate Blackburn
kate.blackburn@asco.org
571-483-1379
American Society of Clinical Oncology

Public Release: 10-Nov-2014
New England Journal of Medicine
Lung cancer screening with low-dose CT could be cost effective says Dartmouth study
Dartmouth researchers say lung cancer screening in the National Lung Screening Trial meets a commonly accepted standard for cost effectiveness as reported in the Nov. 6 issue of the New England Journal of Medicine. This relatively new screening test uses annual low-dose CT scans to spot lung tumors early in individuals facing the highest risks of lung cancer due to age and smoking history.
NIH/National Cancer Institute

Contact: Rick Adams
Clarence.R.Adams@hitchcock.org
603-653-1910
The Geisel School of Medicine at Dartmouth

Public Release: 10-Nov-2014
Record grant will continue inner-city asthma research
The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded the University of Wisconsin School of Medicine and Public Health a seven-year, $70 million grant for its continuing work on the Inner-City Asthma Consortium -- a nationwide clinical research network to evaluate and develop promising new immune-based treatments. The goal of the work is to reduce the severity of asthma in inner-city children.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Gian Galassi
ggalassi@uwhealth.org
608-263-5561
University of Wisconsin-Madison

Public Release: 10-Nov-2014
Proceedings of the National Academy of Sciences
The cat's meow: Genome reveals clues to domestication
Cats and humans have shared the same households for at least 9,000 years, but we still know very little about how our feline friends became domesticated. An analysis of the cat genome by researchers at Washington University School of Medicine in St. Louis reveals some surprising clues. The research appears Nov. 10 in the Proceedings of the National Academy of Sciences Early Edition.
NIH/National Human Genome Research Institute , National Science Foundation, Morris Animal Foundation, European Research Council, Government of Spain, National Center for Resarch Resources, Winn Feline Foundation

Contact: Diane Duke Williams
williamsdia@wustl.edu
314-286-0111
Washington University School of Medicine

Public Release: 10-Nov-2014
Personal Relationships
Is your relationship moving toward marriage? If it isn't, you probably can't admit it
Dating couples who have moved toward marriage over the course of their relationship remember accurately what was going on at each stage of their deepening commitment. But couples whose commitment to each other has stagnated or regressed are far less accurate in their memories of their relationships, says a new University of Illinois study.
NIH/National Institute of Mental Health

Contact: Phyllis Picklesimer
p-pickle@illinois.edu
217-244-2827
University of Illinois College of Agricultural, Consumer and Environmental Sciences

Public Release: 10-Nov-2014
Journal of Clinical Investigation
Scientists uncover a role for carbon monoxide in battling bacterial infections
New findings support the possibility that, in the future, small non-toxic doses of CO could provide the immune system with an infection-fighting advantage.
National Institutes of Health, American Heart Associtation, Howard Hughes Medical Institute

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center

Public Release: 10-Nov-2014
Proceedings of the National Academy of Sciences
Playing action video games can boost learning
A new study shows for the first time that playing action video games improves not just the skills taught in the game, but learning capabilities more generally.
US Office of Naval Research-Multi University Research Initiative, National Institutes of Health, Swiss National Foundation, Human Frontier Science Program, Swiss National Fund, NIH/National Eye Institute

Contact: Monique Patenaude
monique.patenaude@rochester.edu
585-276-3693
University of Rochester

Public Release: 10-Nov-2014
American Journal of Pathology
Major blood vessel constrictor contributes to vision loss in premies
A gene known to play a major role in constricting blood vessels also appears to be a major player in the aberrant blood vessel growth that can destroy the vision of premature babies, according to research at the Medical College of Georgia.
NIH/National Eye Institute, US Department of Veterans Affairs, American Heart Association

Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University

Public Release: 10-Nov-2014
Proceedings of the National Academy of Sciences
'Darting' mice may hold clues to ADHD, autism and bipolar disorder
A darting mouse may hold an important clue in the development of attention deficit hyperactivity disorder (ADHD), autism and bipolar disorder, according to a study by a Vanderbilt University-led research team recently published in the Proceedings of the National Academy of Sciences.
National Institutes of Health

Contact: Craig Boerner
craig.boerner@vanderbilt.edu
615-322-4747
Vanderbilt University Medical Center

Public Release: 10-Nov-2014
Nature Neuroscience
Statins reverse learning disabilities caused by genetic disorder
UCLA neuroscientists discovered that statins, a popular class of cholesterol drugs, reverse the learning deficits caused by a mutation linked to a common genetic cause of learning disabilities. Published in the Nov. 10 advance online edition of Nature Neuroscience, the findings were studied in mice genetically engineered to develop the disease, called Noonan syndrome.
NIH/National Institute of Mental Health

Contact: Elaine Schmidt
eschmidt@mednet.ucla.edu
310-794-2272
University of California - Los Angeles Health Sciences

Public Release: 10-Nov-2014
Nature
Thousands of never-before-seen human genome variations uncovered
Thousands of never-before-seen genetic variants in the human genome have been uncovered using a new genome sequencing technology. These discoveries close many human genome mapping gaps that have long resisted sequencing. The technique, called single-molecule, real-time DNA sequencing, may now make it possible for researchers to identify potential genetic mutations behind many conditions whose genetic causes have long eluded scientists.
National Institutes of Health, NIH/National Institute of Neurological Disorders and Stroke, Howard Hughes Medical Institute

Contact: Michael McCarthy
leilag@uw.edu
206-543-3620
University of Washington Health Sciences/UW Medicine

Public Release: 10-Nov-2014
Cancer Discovery
Mayo Clinic researchers identify first steps in formation of pancreatic cancer
Researchers at Mayo Clinic's campus in Jacksonville say they have identified first steps in the origin of pancreatic cancer and that their findings suggest preventive strategies to explore.
National Institutes of Health

Contact: Kevin Punsky
punsky.kevin@mayo.edu
904-953-0746
Mayo Clinic

Public Release: 10-Nov-2014
Nature Genetics
Re-learning how to read a genome
There are roughly 20,000 genes and thousands of other regulatory 'elements' stored within our DNA. Somehow all of this coded information needs to be read and transcribed into messages that can be used by cells. New research has revealed that the initial steps of the reading process are actually remarkably similar at both genes and regulatory elements. The main differences seem to occur after the initial step, in the length and stability of the messages.
National Institutes of Health

Contact: Jaclyn Jansen
jjansen@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory

Public Release: 10-Nov-2014
Nature Neuroscience
Some neurons can multitask, raising questions about the importance of specialization
The brain is constantly processing sensory information while supporting a dizzying array of behaviors. For decades, biologists have assumed that specialized classes of neurons process all this information at once. But a team of scientists at CSHL has found a population of neurons in the rat brain that support multiple behaviors at once. These neurons cannot be individually classified by specialization, challenging assumptions about how information is encoded in the brain.
National Institutes of Health, John Merck Fund, McKnight Foundation, Marie Robertson Memorial Fund of Cold Spring Harbor Laboratory, Swartz Foundation Fellowship

Contact: Jaclyn Jansen
jjansen@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory

Public Release: 10-Nov-2014
Nature
Catalyst-where-you-want-it method expands the possibilities for new drug development
Chemists at The Scripps Research Institute and the Shanghai Institute of Organic Chemistry have described a method for creating and modifying organic compounds that overcomes a major limitation of previous methods.
Chinese Academy of Sciences, NIH/National Institute of General Medical Sciences

Contact: Madeline McCurry-Schmidt
madms@scripps.edu
858-784-9254
Scripps Research Institute

Public Release: 10-Nov-2014
JAMA Pediatrics
Overall risk of birth defects appears low for women taking antiretrovirals during early pregnancy
Among pregnant women infected with HIV, the use of antiretroviral medications early in pregnancy to treat their HIV or to prevent mother-to-child transmission of HIV does not appear to increase the risk of birth defects in their infants, according to a new study led by Harvard School of Public Health.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development,NIH/National Institute on Drug Abuse, NIH/National Institute of Allergy and Infectious Diseases, NIH/National Institute of Mental Health, and others

Contact: Marge Dwyer
mhdwyer@hsph.harvard.edu
617-432-8416
Harvard School of Public Health

Public Release: 10-Nov-2014
Journal of Clinical Investigation
Tumor-associated neutrophils boost anti-tumor immune responses
A new study in the Journal of Clinical Investigation suggests that tumor-associated neutraphils help bolster the immune response against lung tumors.
National Institutes of Health, Janssen Pharmaceuticals, Lung Cancer Translation Center of Excellence of the Abramson Cancer Center at the University of Pennsylvania

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 10-Nov-2014
Journal of Clinical Investigation
Cervical component protects against infection and preterm birth in mice
A new study in the Journal of Clinical Investigation demonstrates that the cervical component hyaluronan provides protection against infection-induced preterm birth.
National Institutes of Health

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 10-Nov-2014
Cancer Cell
Classification of gene mutations in a children's cancer may point to improved treatments
Oncology researchers studying gene mutations in the children's cancer neuroblastoma are refining their diagnostic tools to predict which patients are more likely to respond to drugs called ALK inhibitors that target such mutations.
National Institutes of Health, US Army Peer-Reviewed Medical Research Program, National Science Foundation

Contact: Rachel Salis-Silverman
Salis@email.chop.edu
267-426-6063
Children's Hospital of Philadelphia

Public Release: 10-Nov-2014
Proceedings of the National Academy of Sciences
How cartilage cells sense forceful injury
Duke scientists are closer to understanding how cartilage senses injury-causing mechanical strain at the cellular level: a pair of channels that work together to cause cartilage cells to die off in droves. Using a substance found in tarantula venom to block these channels, the researchers have prevented cell death caused when cartilage cells detect mechanical strain. The findings could lead to drug targets for protecting joints and preventing the pain associated with cartilage injuries.
National Institutes of Health

Contact: Karl Bates
karl.bates@duke.edu
919-681-8054
Duke University

Public Release: 10-Nov-2014
Proceedings of the National Academy of Sciences
Study shows marijuana's long-term effects on the brain
The effects of chronic marijuana use on the brain may depend on age of first use and duration of use, according to researchers at the Center for BrainHealth at The University of Texas at Dallas. In a paper published today in Proceedings of the National Academy of Sciences (PNAS), researchers for the first time comprehensively describe existing abnormalities in brain function and structure of long-term marijuana users with multiple magnetic resonance imaging (MRI) techniques.
NIH/National Institute on Drug Abuse

Contact: Shelly Kirkland
shelly.kirkland@utdallas.edu
972-883-3221
Center for BrainHealth

Public Release: 10-Nov-2014
Cancer Cell
Researchers find new target for kidney cancer therapy
Cincinnati Cancer Center researchers have discovered that a membrane channel, Transient Receptor Potential Melastatin 3, or TRPM3, promotes growth of kidney cancer tumors, and targeting this channel therapeutically could lead to more treatments for a disease that currently has few treatment options.
National Institutes of Health, Veterans Affairs Merit Award, UC Center for Environmental Genetics Award

Contact: Katie Pence
katie.pence@uc.edu
513-558-4561
University of Cincinnati Academic Health Center

Public Release: 7-Nov-2014
Journal of the American Board of Family Medicine
Nurse navigators may aid colon cancer screening follow-up
Group Health patients with a positive screening test for colon cancer (a stool test or sigmoidoscopy) tended to be more likely to get the recommended follow-up test, a diagnostic colonoscopy, if nurse navigators contacted them than if they got usual care, according to Beverly B. Green, MD, MPH, a Group Health physician and a Group Health Research Institute associate investigator.
NIH/National Cancer Institute

Contact: Joan DeClaire
declaire.j@ghc.org
206-287-2653
Group Health Research Institute

Showing releases 3001-3025 out of 3753.

<< < 116 | 117 | 118 | 119 | 120 | 121 | 122 | 123 | 124 | 125 > >>

     
   

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