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Key: Meeting M      Journal J      Funder F

Showing releases 3026-3050 out of 3554.

<< < 117 | 118 | 119 | 120 | 121 | 122 | 123 | 124 | 125 | 126 > >>

Public Release: 27-Jan-2014
EMBO Journal
Cannabis during pregnancy endangers fetal brain development
A current study by an international consortium of researchers, including researchers from Karolinska Institutet in Sweden, shows that the consumption of Cannabis during pregnancy can impair the development of the fetus' brain with long-lasting effects after birth. Cannabis is particularly powerful to derail how nerve cells form connections, potentially limiting the amount of information the affected brain can process.
Swedish Research Council, Wellcome Trust, National Institutes of Health, and others

Contact: Press Office
Karolinska Institutet

Public Release: 27-Jan-2014
Proceedings of the National Academy of Sciences
Persistent HIV replication associated with lower drug concentrations in lymphatic tissues
Drugs used to treat HIV penetrate poorly into lymphatic tissues where most HIV replication takes place and there is persistent low-level virus replication in these tissues according to research from the University of Minnesota and University of Nebraska Medical Center.
National Institutes of Health

Contact: Caroline Marin
University of Minnesota Academic Health Center

Public Release: 27-Jan-2014
Journal of General Physiology
Protecting the skin from sun exposure
The ultraviolet radiation (UVR) present in sunlight is the most common environmental carcinogen. To develop better methods of protection from the sun, we need to understand how the human skin detects and responds to UVR. Researchers provide new insight into the molecular pathway underlying this process.
National Institutes of Health, National Science Foundation, Brown University

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 27-Jan-2014
Journal of General Physiology
A trigger for muscular diseases
Various muscular diseases are associated with changes in the elasticity of the protein titin, but whether these changes are a cause or an effect of disease has been unclear. Researchers help solve this "chicken or the egg" conundrum and identify a key player in determining titin's size and stiffness.
Bellows Foundation, Achievement Rewards for College Scientists Foundation, American Heart Association, National Institutes of Health

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 26-Jan-2014
Nature Biotechnology
Shortening guide RNA markedly improves specificity of CRISPR-Cas nucleases
A simple adjustment to a powerful gene-editing tool may be able to improve its specificity. Massachusetts General Hospital investigators have found that adjusting the length of the the guide RNA component of the synthetic enzymes called CRISPR-Cas RNA-guided nucleases can substantially reduce the occurrence of off-target DNA mutations.
National Institutes of Health

Contact: Sue McGreevey
Massachusetts General Hospital

Public Release: 26-Jan-2014
Nature Medicine
Cleveland Clinic researchers discover process that turns 'good cholesterol' bad
Cleveland Clinic researchers have discovered the process by which high-density lipoprotein -- the so-called "good cholesterol" -- becomes dysfunctional, loses its cardio-protective properties, and instead promotes inflammation and atherosclerosis, or the clogging and hardening of the arteries. Their research was published online today in the journal Nature Medicine.
National Institutes of Health

Contact: Laura Ambro
Cleveland Clinic

Public Release: 24-Jan-2014
Journal of Immunology
Immune system drives pregnancy complications after fetal surgery in mice
UCSF researchers have shown that, in mice at least, pregnancy complications after fetal surgery are triggered by activation of the mother's T cells.
California Institute for Regenerative Medicine, National Institutes of Health, National Science Foundation, March of Dimes

Contact: Juliana Bunim
University of California - San Francisco

Public Release: 24-Jan-2014
PLOS Biology
Biases in animal studies may differ from those in clinical trials, UCSF study finds
A new analysis of animal studies on cholesterol-lowering statins by UC San Francisco researchers found that non-industry studies had results that favored the drugs even more than studies funded by industry.
NIH/National Institute of Environmental Health Sciences

Contact: Laura Kurtzman
University of California - San Francisco

Public Release: 24-Jan-2014
Cancer Discovery
Scientists develop powerful new animal model for metastatic prostate cancer
Prostate cancer is the most common form of cancer in men, yet research has been stymied by imperfect animal models of the disease. Now, CSHL scientists have developed a new method to rapidly create much better mouse models for the most lethal, terminal events of metastatic prostate cancer. This discovery allows scientists to investigate the causes of the disease while at the same time testing new therapeutics to treat it.
National Institutes of Health, US Department of the Army, STARR Foundation, Robertson Research Fund

Contact: Jaclyn Jansen
Cold Spring Harbor Laboratory

Public Release: 24-Jan-2014
Perspectives on Psychological Science
Researchers use sensory integration model to understand unconscious priming
Priming, an unconscious phenomenon that causes the context of information to change the way we think or behave, has frustrated scientists as they have unsuccessfully attempted to understand how it works. But, recent failures to replicate demonstrations of unconscious priming have resulted in a heated debate within the field of psychology. In a breakthrough paper, Carnegie Mellon University researchers use a well-established human perception theory to illustrate the mechanisms underlying priming and explain how its effects do not always act as predicted.
National Science Foundation, NIH/National Institute of Mental Health, Pittsburgh Life Sciences Greenhouse Opportunity Fund

Contact: Shilo Rea
Carnegie Mellon University

Public Release: 24-Jan-2014
Academic Radiology
Researchers developing new approach for imaging dense breasts for abnormalities
Dartmouth engineers and radiologists develop new approach for diagnostic imaging of dense breasts with suspicious lesions. MRI/near-infrared spectroscopy technique offers greater flexibility, speed, and accuracy. Technology shows promise for improving MRI's ability to distinguish cancer from benign abnormalities.
National Institutes of Health

Contact: Donna Dubuc
The Geisel School of Medicine at Dartmouth

Public Release: 24-Jan-2014
Annals of Internal Medicine
Loyola physician research shows gap in care for childhood cancer survivors
A recent study shows that many internists feel ill-equipped to care for adult patients who are childhood cancer survivors. Eugene Suh, MD, assistant professor in the division of Pediatric Hematology and Oncology at Loyola University Chicago Stritch School of Medicine, was the first author on the study.
NIH/National Cancer Institute

Contact: Evie Polsley
Loyola University Health System

Public Release: 24-Jan-2014
Journal of Neuroscience
CWRU researchers find epileptic activity spreads in new way
Researchers in the biomedical engineering department at Case Western Reserve University have found that epileptic activity can spread through a part of the brain in a new way, suggesting a possible novel target for seizure-blocking medicines. Evidence from a series of experiments and computer modeling strongly suggests individual cells in a part of the brain, known as the hippocampus, use a small electrical field to stimulate and synchronize neighboring cells, spreading the activity layer by layer.
National Institutes of Health

Contact: Kevin Mayhood
Case Western Reserve University

Public Release: 24-Jan-2014
Otology & Neurotology
Aspirin intake may stop growth of vestibular schwannomas/acoustic neuromas
Researchers from Massachusetts Eye and Ear, Harvard Medical School, Massachusetts Institute of Technology and Massachusetts General Hospital have demonstrated, for the first time, that aspirin intake correlates with halted growth of vestibular schwannomas (also known as acoustic neuromas), a sometimes lethal intracranial tumor that typically causes hearing loss and tinnitus.
Bertarelli Foundation, NIH/National Institute on Deafness and Other Communication Disorders

Contact: Mary Leach
Massachusetts Eye and Ear Infirmary

Public Release: 24-Jan-2014
Highly reliable brain-imaging protocol identifies delays in premature infants
Infants born prematurely are at elevated risk for cognitive, motor, and behavioral deficits -- the severity of which was, until recently, almost impossible to accurately predict in the neonatal period with conventional brain-imaging technology. But physicians may now be able to identify the premature infants most at risk for deficits as well as the type of deficit, enabling them to quickly initiate early neuroprotective therapies, by using highly reliable 3-D MRI imaging techniques developed by clinician scientists.
Research Institute at Nationwide Children's Hospital, NIH/National Center for Research Resources

Contact: Gina Bericchia
Nationwide Children's Hospital

Public Release: 23-Jan-2014
Journal of Cell Biology
Putting a brake on tumor spread
A team of scientists, led by principal investigator David D. Schlaepfer, Ph.D., a professor in the Department of Reproductive Medicine at the University of California, San Diego School of Medicine, has found that a protein involved in promoting tumor growth and survival is also activated in surrounding blood vessels, enabling cancer cells to spread into the bloodstream.
National Institutes of Health, Italian Association for Cancer Research

Contact: Scott LaFee
University of California - San Diego

Public Release: 23-Jan-2014
Journal of Biomedical Optics
A scientific first: Physicists, physicians, engineers photograph radiation beams in the human body through the Cherenkov effect
A scientific breakthrough may give the field of radiation oncology new tools to increase the precision and safety of radiation treatment in cancer patients by helping doctors "see" the powerful beams of a linear accelerator as they enter or exit the body.
NIH/National Cancer Institute

Contact: Donna Dubuc
The Geisel School of Medicine at Dartmouth

Public Release: 23-Jan-2014
Lab-grown, virus-free stem cells repair retinal tissue in mice
Investigators at Johns Hopkins report they have developed human induced-pluripotent stem cells capable of repairing damaged retinal vascular tissue in mice. The stem cells, derived from human umbilical cord-blood and coaxed into an embryonic-like state, were grown without the conventional use of viruses, which can mutate genes and initiate cancers, according to the scientists.
Maryland Stem Cell Research, NIH/National Heart, Lung, and Blood Institute, NIH/National Eye Institute

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 23-Jan-2014
Cell Reports
New computer model may aid personalized cancer care
Researchers at Dana-Farber Cancer Institute have developed a tool to help predict how a patient's tumor is likely to behave and which of several possible treatments is most likely to be effective.
NIH/National Cancer Institute, US Department of Energy, Breast Cancer Research Foundation

Contact: Robbin Ray
Dana-Farber Cancer Institute

Public Release: 23-Jan-2014
American Journal of Pathology
New clues may link hereditary cancer genes to increased risk of cancer from alcohol
In laboratory experiments conducted on human cell lines at the Johns Hopkins Kimmel Cancer Center, scientists have shown that people carrying certain mutations in two hereditary cancer genes, BRCA2 and PALB2, may have a higher than usual susceptibility to DNA damage caused by a byproduct of alcohol, called acetaldehyde.
NIH/National Cancer Institute, Everett and Marjorie Kovler Professorship in Pancreas Cancer Research

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 23-Jan-2014
Team to study control of malaria-related parasite growth with $2.1-million NIH grant
A University of South Florida team has been awarded a $2.1-million National Institutes of Health grant to study the "control room" that regulates cell replication in malaria-related parasites. The research may identify new factors promoting Toxoplasma growth and lead to new therapies to combat malaria.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Anne DeLotto Baier
University of South Florida (USF Health)

Public Release: 23-Jan-2014
Journal of Consulting and Clinical Psychology
CWRU study finds depression symptoms and emotional support impact PTSD treatment progress
Researchers at Case Western Reserve University found that during PTSD treatments, rapid improvements in depression symptoms are associated with better outcomes.
NIH/National Institute of Mental Health

Contact: Susan Griffith
Case Western Reserve University

Public Release: 23-Jan-2014
Nature Chemical Biology
Johns Hopkins scientists identify a key to body's use of free calcium
Scientists at Johns Hopkins report they have figured out a key step in how "free" calcium -- the kind not contained in bones -- is managed in the body, a finding that could aid in the development of new treatments for a variety of neurological disorders that include Parkinson's disease.
NIH/National Institute of General Medical Sciences, NIH/National Heart, Lung and Blood Institute, NIH/National Institute of Mental Health, NIH/National Institute on Deafness and Other Communication Disorders

Contact: Catherine Kolf
Johns Hopkins Medicine

Public Release: 23-Jan-2014
Moderate doses of radiation therapy to unaffected breast may prevent second breast cancers
Survivors of breast cancer have a one in six chance of developing breast cancer in the other breast. But a study conducted in mice suggests that survivors can dramatically reduce that risk through treatment with moderate doses of radiation to the unaffected breast at the same time that they receive radiation therapy to their affected breast. The treatment, if it works as well in humans as in mice, could prevent tens of thousands of second breast cancers.
NIH/National Institute of Allergy and Infectious Diseases, Irving Institute for Clinical and Translational Research at Columbia University

Contact: Karin Eskenazi
Columbia University Medical Center

Public Release: 23-Jan-2014
ACS Chemical Biology
Researchers discover potential drug targets for early onset glaucoma
Using a novel high-throughput screening process, scientists have for the first time identified molecules with the potential to block the accumulation of a toxic eye protein that can lead to early onset of glaucoma.
National Institutes of Health

Contact: Brett Israel
Georgia Institute of Technology

Showing releases 3026-3050 out of 3554.

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