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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 3026-3050 out of 3522.

<< < 117 | 118 | 119 | 120 | 121 | 122 | 123 | 124 | 125 | 126 > >>

Public Release: 19-Dec-2013
Cell
A new -- and reversible -- cause of aging
Researchers have discovered a cause of aging in mammals involving a series of molecular events that disables communication between the nucleus and mitochondria. By administering a molecule naturally produced by the human body, the communication network was restored in older mice. Subsequent tissue samples showed biological hallmarks comparable to much younger animals.
NIH/National Institute on Aging, Glenn Foundation for Medical Research, and others

Contact: David Cameron
david_cameron@hms.harvard.edu
617-432-0441
Harvard Medical School

Public Release: 19-Dec-2013
Science
Cocaine, meth response differ between 2 substrains of 'Black 6' laboratory mouse
Researchers including Jackson Laboratory Professor Gary Churchill, Ph.D., have found a single nucleotide polymorphism difference in cocaine and methamphetamine response between two substrains of the C57BL/6 or "Black 6" inbred laboratory mouse, pointing to Cyfip2 as a regulator of cocaine response with a possible role in addiction.
NIH/National Institute on Drug Abuse

Contact: Joyce Peterson
joyce.peterson@jax.org
207-288-6058
Jackson Laboratory

Public Release: 19-Dec-2013
Science
Gene transfer gone wild reveals driving force behind mitochondrial sex
Pioneering research led by Indiana University has identified genes from a number of plant species, including the entire mitochondrial genomes from three green algae and one moss, in the mitochondrial genome of Amborella trichopoda. The South Pacific shrub is considered to be the sole survivor -- the "last man standing" -- of one of the two oldest lineages of flowering plants, while the other lineage comprises the other 300,000 species of flowering plants.
National Institutes of Health, National Science Foundation, US Department of Energy

Contact: Stephen Chaplin
stjchap@iu.edu
812-856-1896
Indiana University

Public Release: 18-Dec-2013
Stem Cells
Stem cells offer clues to reversing receding hairlines
Regenerative medicine may offer ways to banish baldness that don't involve toupees. The lab of USC scientist Krzysztof Kobielak, M.D., Ph.D., has published a trio of papers in the journals Stem Cells and The Proceedings of the National Academy of Sciences that describe some of the factors that determine when hair grows, when it stops growing and when it falls out.
National Institutes of Health, California Institute for Regenerative Medicine

Contact: Cristy Lytal
lytal@med.usc.edu
University of Southern California - Health Sciences

Public Release: 18-Dec-2013
Fatigue, a common side effect of breast cancer treatment, evaluated in novel patient study
Although the prevalence and impact of cancer-related fatigue has been well established, very little is known about its predictors, mechanisms for development, and persistence post-treatment. A new research study at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, in partnership with UCLA, is aimed at identifying breast cancer patients most susceptible to post-treatment fatigue by measuring biological, behavioral and social risk factors.
National Institutes of Health

Contact: Cara Martinez
cara.martinez@cshs.org
310-423-7798
Cedars-Sinai Medical Center

Public Release: 18-Dec-2013
Journal of Clinical Investigation
Role for sugar uptake in breast cancer revealed
Berkeley Lab researchers have shown that aerobic glycolysis -- glucose metabolism in the presence of oxygen -- is not the consequence of the cancerous activity of malignant cells, as has been widely believed, but is itself a cancerous event.
NIH/National Cancer Institute

Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory

Public Release: 18-Dec-2013
Nature
Neanderthal genome shows early human interbreeding, inbreeding
A team that includes UC Berkeley population geneticists has produced the first high-quality genome of a Neanderthal, allowing comparison with the genomes of modern humans and Denisovans. The analysis shows a long history of interbreeding among these early humans and a fourth, previously unknown group. The Neanderthal, from Denisova cave, also shows evidence of inbreeding. About 87 genes in modern humans were found to be significantly different from related genes in Neanderthals and Denisovans.
National Institutes of Health

Contact: Robert Sanders
rlsanders@berkeley.edu
510-643-6998
University of California - Berkeley

Public Release: 18-Dec-2013
Nature Communications
Going against the flow: Halting atherosclerosis by targeting micro RNA
Researchers at Emory and Georgia Tech have developed a potential treatment for atherosclerosis that targets a master controller of the process.
NIH/National Heart, Lung and Blood Institute

Contact: Quinn Eastman
qeastma@emory.edu
404-727-7829
Emory Health Sciences

Public Release: 18-Dec-2013
JAHA: Journal of the American Heart Association
Heart disease linked with dementia in older postmenopausal women
Heart disease is linked with decreased brain function in older postmenopausal women. Women who have high blood pressure or diabetes may be at higher risk for decreasing brain function over time.
National Institutes of Health

Contact: Bridgette McNeill
bridgette.mcneill@heart.org
214-706-1135
American Heart Association

Public Release: 18-Dec-2013
JAMA Psychiatry
Markers of inflammation in the blood linked to aggressive behaviors
People with intermittent explosive disorder -- a psychiatric illness characterized by impulsivity, hostility and recurrent aggressive outbursts -- have elevated levels of two markers of systemic inflammation in their blood. The study documents a direct relationship between inflammatory markers and impulsive aggression that is not seen in people in good mental health or with other psychiatric disorders.
NIH/National Institute of Mental Health, University of Colorado, Denver

Contact: John Easton
john.easton@uchospitals.edu
773-795-5225
University of Chicago Medical Center

Public Release: 18-Dec-2013
Neuron
Brain area attacked by Alzheimer's links learning and rewards
One of the first areas of the brain to be attacked by Alzheimer's disease, the posterior cingulate cortex, or PCC, has been found to step in during a cognitive challenge to improve the brain's performance. This small study in monkeys establishes a role for the PCC in learning and its connection to the brain's reward system.
National Institutes of Health

Contact: Karl Leif Bates
karl.bates@duke.edu
919-681-8054
Duke University

Public Release: 18-Dec-2013
PLOS ONE
Stress reaction gene linked to death, heart attacks
A genetic trait known to make some people especially sensitive to stress also appears to be responsible for a 38 percent increased risk of heart attack or death in patients with heart disease, scientists at Duke Medicine report.
NIH/National, Heart, Lung, and Blood Institute

Contact: Sarah Avery
sarah.avery@duke.edu
919-660-1306
Duke University Medical Center

Public Release: 18-Dec-2013
Science Translational Medicine
Newly identified immune receptor may activate B cells in autoimmunity
A newly identified immune protein influences each person's response to vaccines and risk for autoimmune diseases like lupus and multiple sclerosis. The protein, called a receptor and part of signaling pathways, also provides a new target for personalized therapies for patients with autoimmune diseases.
National Institutes of Health, American College of Rheumatology

Contact: Greg Williams
gdw@uab.edu
205-721-0710
University of Alabama at Birmingham

Public Release: 18-Dec-2013
PLOS ONE
No link between HIV-prevention pill Truvada and increased sexual risk behavior
In 2012 the HIV antiretroviral drug Truvada became the first and only medication approved by the FDA for HIV prevention. Led by Gladstone Institutes' Investigator Robert Grant, M.D., M.P.H., this research was hailed as an important step towards reducing the worldwide HIV/AIDS epidemic. Now, a new study provides further proof that regular Truvada use can reduce one's risk for contracting HIV -- without increasing sexual risk behavior.
National Institutes of Health, Bill and Melinda Gates Foundation

Contact: Anne Holden
anne.holden@gladstone.ucsf.edu
415-734-2534
Gladstone Institutes

Public Release: 17-Dec-2013
Stem Cells
Muscle-invasive and non-muscle invasive bladder cancers arise from different stem cells
A CU Cancer Center study published today in the journal Stem Cells shows that progenitor cells that create dangerous, muscle-invasive bladder cancer are different than the progenitor cells that create non-muscle invasive bladder cancer. Though these two cancers grow at the same site, they are different diseases.
National Institutes of Health

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 17-Dec-2013
Vaccine
Study: Moderate alcohol consumption boosts body's immune system
Medical science has known for years that people who drink moderate amounts of alcohol actually have a reduced risk of death. Now, new research from Oregon Health & Science University adds a fascinating twist: moderate drinking may actually bolster our immune system and help it fight off infection.
National Institutes of Health, NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Todd Murphy
murphyt@ohsu.edu
503-494-8231
Oregon Health & Science University

Public Release: 17-Dec-2013
Childhood Obesity
TV ads nutritionally unhealthy for kids, study finds
The nutritional value of food and drinks advertised on children's television programs is worse than food shown in ads during general air time, according to a new study.
US Centers for Disease Control and Prevention, NIH/National Cancer Institute, Robert Wood Johnson Foundation

Contact: Sherri McGinnis Gonzalez
smcginn@uic.edu
312-996-8277
University of Illinois at Chicago

Public Release: 17-Dec-2013
Nature Neuroscience
Silencing synapses
Imagine kicking a cocaine addiction by simply popping a pill that alters the way your brain processes chemical addiction. New research from the University of Pittsburgh suggests that a method of biologically manipulating certain neurocircuits could lead to a pharmacological approach that would weaken post-withdrawal cocaine cravings. The findings have been published in Nature Neuroscience.
National Institutes of Health National Institute on Drug Abuse, German Research Foundation

Contact: Joe Miksch
jmiksch@pitt.edu
412-624-4358
University of Pittsburgh

Public Release: 17-Dec-2013
Journal of the American Chemical Society
Water in cells behaves in complex and intricate ways
In a sort of biological "spooky action at a distance," water in a cell slows down in the tightest confines between proteins and develops the ability to affect other proteins much farther away, University of Michigan researchers have discovered.
National Science Foundation, National Institutes of Health, Camille and Henry Dreyfus Foundation

Contact: Nicole Casal Moore
ncmoore@umich.edu
734-647-7087
University of Michigan

Public Release: 17-Dec-2013
Molecular Cancer Research
Study finds known lung cancer oncogenes ALK and ROS1 also drive colorectal cancer
A University of Colorado Cancer Center study published online ahead of print in the journal Molecular Cancer Research shows that ALK and ROS1 gene rearrangements known to drive subsets of lung cancer are also present in some colorectal cancers. These results imply that drugs used to target ALK and ROS1 in lung cancer may also have applications in this subset of colorectal cancer patients.
NIH/National Cancer Institute

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 17-Dec-2013
Cell Reports
UCLA study challenges long-held hypothesis that iron promotes atherosclerosis
A UCLA research team has found no evidence of an association between iron levels in the body and the risk of atherosclerosis. The discovery, based on a comprehensive study in a mouse model of atherosclerosis, contradicts a long-held hypothesis about the role of iron in the disease and carries important implications for patients with chronic kidney disease or anemia related to inflammatory disorders, many of whom receive high-dose iron supplementation therapy.
National Institutes of Health

Contact: Rachel Champeau
rchampeau@mednet.ucla.edu
310-794-2270
University of California - Los Angeles Health Sciences

Public Release: 17-Dec-2013
Demography
Poor health of Irish immigrants in England may be linked to childhood abuse, study finds
Irish immigrants to England during most of the 20th century generally suffered from poor health, in contrast to the general pattern where immigrants are healthier than the native population. A new study suggests that the troubles were not caused primarily by the difficulties of assimilation or tensions between the two nations, but by the abuse Irish expatriates suffered as children in their homeland.
Fulbright Commission, Center for Health and Wellbeing, NIH/National Institute of Aging

Contact: Warren Robak
robak@rand.org
310-451-6913
RAND Corporation

Public Release: 17-Dec-2013
2013 ASCB Annual Meeting
Researchers explain why some wound infections become chronic
Why does treating chronic wounds cost so much? What complicates chronic wound infections, making healing difficult? Manuela Martins-Green, professor of cell biology at the University of California, Riverside, reports at a meeting in New Orleans today that two biological activities are out of control in chronic wound infections. These are reactive oxygen species, which are chemically reactive molecules formed by the partial reduction of oxygen, and biofilms that are formed by selective invading bacteria.
National Institutes of Health

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside

Public Release: 17-Dec-2013
Journal of Clinical Investigation
Moffitt researchers discover mechanism controlling the development of myelodysplastic
Researchers at the Moffitt Cancer Center have discovered a control mechanism that can trigger the development of myelodysplastic syndromes, a group of blood cancers. This finding may lead to therapies capable of preventing the progression of these diseases.
National Institute of Health, NIH/National Cancer Institute, US Army Medical Research & Materiel Command

Contact: Kim Polacek
kim.polacek@moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 17-Dec-2013
Pitt-led network gets $70 million over 7 years to develop, test HIV prevention products
With funding of $70 million to support its effort into 2021, the Microbicide Trials Network will continue to develop and test products that aim to reduce the spread of HIV. The extensive program, based at the University of Pittsburgh and Magee-Womens Research Institute, has completed 13 trials since 2006; 11 more are in progress or will begin within the year; and new studies will be designed and implemented during the next funding period.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Anita Srikameswaran
SrikamAV@upmc.edu
412-578-9193
University of Pittsburgh Schools of the Health Sciences

Showing releases 3026-3050 out of 3522.

<< < 117 | 118 | 119 | 120 | 121 | 122 | 123 | 124 | 125 | 126 > >>

     
   

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