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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3051-3075 out of 3462.

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Public Release: 10-Oct-2013
University of Utah awarded $20.4 million from NIH to advance translational research in medicine
The Center's track record of success this month has earned it a $20.4 million grant from the National Institutes of Health that will allow it to provide support for all aspects of translational research over the next five years.
National Institutes of Health

Contact: Melinda Rogers
University of Utah Health Sciences

Public Release: 10-Oct-2013
Molecular Psychiatry
Sticks and stones: Brain releases natural painkillers during social rejection, U-M study finds
"Sticks and stones may break my bones, but words will never hurt me," goes the playground rhyme that's supposed to help children endure taunts from classmates. But a new study suggests that there's more going on inside our brains when someone snubs us -- and that the brain may have its own way of easing social pain.
National Institutes of Health, Brain & Behavior Research Foundation, Phil F. Jenkins Foundation

Contact: Kara Gavin
University of Michigan Health System

Public Release: 10-Oct-2013
Cleveland institutions receive NIH grant for regional stroke clinical trials coordinating center
Five Cleveland biomedical research and health care institutions have received a $1 million grant from the National Institute of Neurological Disorders and Stroke, one of the National Institutes of Health, to collaborate on developing the Cleveland Stroke Clinical Trials Regional Coordinating Center.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Amanda Petrak
Case Western Reserve University

Public Release: 10-Oct-2013
Journal of Clinical Oncology
Preventable risk factors pose serious threat to heart health of childhood cancer survivors
For childhood cancer survivors, risk factors associated with lifestyle, particularly hypertension, dramatically increase the likelihood of developing serious heart problems as adults, according to a national study led by St. Jude Children's Research Hospital.
NIH/National Cancer Institute, ALSAC

Contact: Summer Feeman
St. Jude Children's Research Hospital

Public Release: 10-Oct-2013
The Cancer Genome Atlas exposes more secrets of lethal brain tumor
Scientists at UT MD Anderson Cancer Center and collaborators paint a more detailed picture of the genomic abnormalities that drive glioblastoma multiforme. Rich data set will underpin research and treatment advances.
National Institutes of Health/The Cancer Genome Atlas

Contact: Scott Merville
University of Texas M. D. Anderson Cancer Center

Public Release: 10-Oct-2013
After almost a century, a question answered; genes protect themselves against being silenced
Harvard Stem Cell Institute researchers have settled a century-old debate over whether occurrence of DNA methylation acts to silence gene expression, or if genes are turned off by other means before they are methylated.
National Institutes of Health

Contact: B. D. Colen
Harvard University

Public Release: 10-Oct-2013
Science Signalling
Scientists find potential new targets for anti-inflammatory therapies
A team led by scientists at The Scripps Research Institute has identified key signaling proteins in the inflammation process that contribute to the development of inflammatory diseases such as rheumatoid arthritis, psoriasis, sepsis and inflammatory bowel diseases. The finding highlights possible new ways of treating these inflammation disorders, which sicken or kill millions of people around the world each year.
National Institutes of Health

Contact: Mika Ono
Scripps Research Institute

Public Release: 10-Oct-2013
Super-enhancers seen as 'Rosetta Stone' for dialog between genes and disease
Having recently discovered a set of powerful gene regulators that control cell identity in a few mouse and human cell types, Whitehead Institute scientists are now showing that these regulators -- which they named "super-enhancers" -- act across a vast array of human cell types and are enriched in mutated regions of the genome that are closely associated with a broad spectrum of diseases.
National Institutes of Health

Contact: Matt Fearer
Whitehead Institute for Biomedical Research

Public Release: 10-Oct-2013
Newly discovered gene regulator could precisely target sickle cell disease
A research team from Dana-Farber/Boston Children's Cancer and Blood Disorders Center and other institutions has discovered a new genetic target for potential therapy of sickle cell disease. The target, called an enhancer, controls a molecular switch in red blood cells called BCL11A that, in turn, regulates hemoglobin production. The researchers -- led by Daniel Bauer, M.D., Ph.D., and Stuart Orkin, M.D., of Dana-Farber/Boston Children's -- reported their findings today in Science.
NIH/National Heart, Lung and Blood Institute, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Doris Duke Charitable Foundation, Howard Hughes Medical Institute

Contact: Irene Sege
Dana-Farber Cancer Institute

Public Release: 10-Oct-2013
Current Biology
Look out above! Experiment explores innate visual behavior in mice
For a mouse in the wild, spotting aerial predators -- like hawks and owls -- is essential to survival. But how is this visual cue processed into a behavior that helps avoid an attack? Using a video technique, researchers at Caltech have developed a simple stimulus to spur the mouse's defense plans: to freeze in place, or flee for cover. These visual behaviors also provide information about cell types in the retina responsible for detecting aerial predators.
National Institutes of Health

Contact: Deborah Williams-Hedges
California Institute of Technology

Public Release: 10-Oct-2013
Cell Metabolism
Eat more, weigh less: Worm study provides clues to better fat-loss therapies for humans
Scientists at The Scripps Research Institute have discovered key details of a brain-to-body signaling circuit that enables roundworms to lose weight independently of food intake. The weight-loss circuit is activated by combined signals from the worm versions of the neurotransmitters serotonin and adrenaline, and there are reasons to suspect that it exists in a similar form in humans and other mammals.
NIH/National Institute for Diabetes, Digestive and Kidney Disorders

Contact: Mika Ono
Scripps Research Institute

Public Release: 10-Oct-2013
Researchers identify liver cancer progenitor cells before tumors become visible
For the first time, researchers at the University of California, San Diego School of Medicine have isolated and characterized the progenitor cells that eventually give rise to malignant hepatocellular carcinoma (HCC) tumors -- the most common form of liver cancer. The researchers found ways to identify and isolate the HCC progenitor cells long before actual tumors were apparent.
Superfund Basic Research Program, National Institutes of Health, Wellcome Trust, American Diabetes Association

Contact: Scott LaFee
University of California - San Diego

Public Release: 10-Oct-2013
Journal of Clinical Hypertension
Overweight and obese children face high risk of hypertension
High body weight in children and adolescents is strongly associated with the likelihood of hypertension, according to a Kaiser Permanente Southern California study published today in The Journal of Clinical Hypertension.
NIH/National Institute of Diabetes and Digestive and Kidney Disorders

Contact: Jennifer Schell
Kaiser Permanente

Public Release: 10-Oct-2013
Previously unstudied gene is essential for normal nerve development
Our ability to detect heat, touch, tickling and other sensations depends on our sensory nerves. Now, for the first time, researchers at Albert Einstein College of Medicine of Yeshiva University have identified a gene that orchestrates the crucially important branching of nerve fibers that occurs during development. The findings were published online today in the journal Cell.
National Institutes of Health

Contact: Deirdre Branley
Albert Einstein College of Medicine

Public Release: 9-Oct-2013
Breast Cancer Research
Does good cholesterol increase breast cancer risk?
A team of Thomas Jefferson University researchers has shown that an HDL receptor found on breast cancer cells may be responsible for making this cancer more aggressive, proposing a new molecular target that could help treat the disease.
The Susan G. Komen Foundation, National Institutes of Health

Contact: Edyta Zielinska
Thomas Jefferson University

Public Release: 9-Oct-2013
Journal of Pathology
Researchers close in on cause of gynecological disease
For the first time, researchers have created a model that could help unlock what causes adenomyosis, a common gynecological disease that is a major contributor to women having to undergo hysterectomies.
National Institutes of Health, American Cancer Society

Contact: Jason Cody
Michigan State University

Public Release: 9-Oct-2013
Researchers identify likely causes, treatment strategies for systemic scleroderma
Using mice, lab-grown cells and clues from a related disorder, Johns Hopkins researchers have greatly increased understanding of the causes of systemic sclerosis, showing that a critical culprit is a defect in the way certain cells communicate with their structural scaffolding. They say the new insights point the way toward potentially developing drugs for the disease, which affects approximately 100,000 people in the United States.
Scleroderma Research Foundation, NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Marfan Foundation, Smilow Center for Marfan Syndrome

Contact: Shawna Williams
Johns Hopkins Medicine

Public Release: 9-Oct-2013
ACS Applied Materials & Interfaces
Scientists use blur to sharpen DNA mapping
Rice researchers have found a simple way to pinpoint the location of specific sequences along single strands of DNA, a technique that could someday help diagnose genetic diseases.
National Science Foundation, National Institutes of Health, Welch Foundation

Contact: David Ruth
Rice University

Public Release: 9-Oct-2013
AIDS and Behavior
Penn study: Visits to multiple HIV clinics linked to poorer outcomes
Patients who received care at multiple HIV clinics -- as opposed to only one -- were less likely to take their medication and had higher HIV viral loads, a new study published in the journal AIDS and Behavior of almost 13,000 HIV patients in Philadelphia from Penn Medicine found. The findings reinforce the notion that continuous care with one provider/clinic is optimal for outcomes and even reducing transmissions, and can help cut down on duplicative HIV services that contribute to higher health care costs.
Penn Center for AIDS Research, National Institutes of Health, Agency for Healthcare Research and Quality

Contact: Steve Graff
University of Pennsylvania School of Medicine

Public Release: 9-Oct-2013
Social Science and Medicine
Household chaos may be hazardous to a child's health
Kindergarten-age children have poorer health if their home life is marked by disorder, noise and a lack of routine and they have a mother who has a chaotic work life, new research suggests.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development

Contact: Claire Kamp Dush
Ohio State University

Public Release: 9-Oct-2013
Single gene mutation linked to diverse neurological disorders
A research team, headed by Theodore Friedmann, M.D., professor of pediatrics at the University of California, San Diego School of Medicine, says a gene mutation that causes a rare but devastating neurological disorder known as Lesch-Nyhan syndrome appears to offer clues to the developmental and neuronal defects found in other, diverse neurological disorders like Alzheimer's, Parkinson's and Huntington's diseases.
National Institutes of Health, Lesch-Nyhan Syndrome Children's Research Foundation

Contact: Scott LaFee
University of California - San Diego

Public Release: 8-Oct-2013
Breathing new life into preterm baby research
Monash University researchers have received a prestigious National Institutes of Health project grant to find ways to improve outcomes for very preterm infants who struggle to take their first breaths.
National Institutes of Health

Contact: Emily Walker
Monash University

Public Release: 8-Oct-2013
Cell Reports
Neurological researchers find fat may be linked to memory loss
Although there are several risk factors of dementia, abnormal fat metabolism has been known to pose a risk for memory and learning. People with high amounts of abdominal fat in their middle age are 3.6 times as likely to develop memory loss and dementia later in their life.
National Institutes of Health

Contact: Deb Song
Rush University Medical Center

Public Release: 8-Oct-2013
Journal of Neuroscience
Study shows how infections in newborns are linked to later behavior problems
Researchers exploring the link between newborn infections and later behavior and movement problems have found that inflammation in the brain keeps cells from accessing iron that they need to perform a critical role in brain development.
National Institutes of Health, Abbott Nutrition

Contact: Jonathan Godbout
Ohio State University

Public Release: 8-Oct-2013
Cerebral Cortex
Where does dizziness come from?
Johns Hopkins researchers say they have pinpointed a site in a highly developed area of the human brain that plays an important role in the subconscious recognition of which way is straight up and which way is down.
NIH/National Institute on Deafness and Other Communication Disorders

Contact: Stephanie Desmon
Johns Hopkins Medicine

Showing releases 3051-3075 out of 3462.

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