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Showing releases 3051-3075 out of 3164.

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Public Release: 20-Dec-2011
'Painless' plasma brush is becoming reality in dentistry, MU engineers say
University of Missouri engineers and their research collaborators at Nanova, Inc. are one step closer to a painless way to replace fillings. After favorable results in the lab, human clinical trials are underway on the "plasma brush."
National Science Foundation and the National Institutes of Health

Contact: Steven Adams
AdamsST@missouri.edu
573-882-8353
University of Missouri-Columbia

Public Release: 20-Dec-2011
$6.75 million awarded to Case Western Reserve to study IBD
Investigators at Case Western Reserve University School of Medicine received a $6.75 million Program Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases to study the role of innate immunity in inflammatory bowel disease.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Jessica Studeny
jessica.studeny@case.edu
216-368-4692
Case Western Reserve University

Public Release: 20-Dec-2011
Boston University researcher awarded 2 NIH grants
Patricia F. Coogan, Sc.D., an associate professor of epidemiology at Boston University's Slone Epidemiology Center, recently was awarded funding for two grants from the National Institutes of Health. The first is a five-year grant from the National Institute of Environmental Health Sciences The second award is for a three-year grant funded by the National Heart, Lung and Blood Institute.
National Institutes of Health

Contact: Gina DiGravio
gina.digravio@bmc.org
617-638-8480
Boston University Medical Center

Public Release: 20-Dec-2011
American Journal of Clinical Nutrition
Early dietary experience shapes salt preference of infants and preschoolers
Researchers from the Monell Center report that 6-month-old infants who have been introduced to starchy table foods, which often contain added salt, have a heightened preference for salty taste. They also were more likely to consume plain salt at preschool age. The findings highlight the potentially significant role of early dietary experience in shaping salty taste preferences of infants and young children.
NIH/National Institute on Deafness and Other Communication Disorders

Contact: Leslie Stein
stein@monell.org
267-519-4707
Monell Chemical Senses Center

Public Release: 19-Dec-2011
Circulation: Journal of the American Heart Association
New predictor of heart attack or stroke
A hike in your blood pressure during middle age significantly raises the risk of having a heart attack or a stroke during your lifetime, according to new Northwestern Medicine research. The study offers a new understanding on the importance of maintaining low blood pressure early in middle age to prevent heart disease later in life.
NIH/National Heart, Lung and Blood Institute

Contact: Marla Paul
marla-Paul@northwestern.edu
312-503-8928
Northwestern University

Public Release: 19-Dec-2011
Biomaterials
UCF nanotechnology may speed up drug testing
Testing the effectiveness of new pharmaceuticals may get faster thanks to a new technique incorporating quantum dots developed at the University of Central Florida.
National Science Foundation, National Institutes of Health

Contact: Zenaida Kotala
zenaida.kotala@ucf.edu
407-823-6120
University of Central Florida

Public Release: 19-Dec-2011
Experimental Biology and Medicine
Acupuncture reduces protein linked to stress in first of its kind animal study
Acupuncture significantly reduces levels of a protein in rats linked to chronic stress, researchers have found. They say their animal study may help explain the sense of well-being that many people receive from this ancient Chinese therapy.
American Association of Nurse Anesthetists, National Institutes of Health

Contact: Karen Mallet
km463@georgetown.edu
Georgetown University Medical Center

Public Release: 19-Dec-2011
Journal of Experimental Social Psychology
1 trait has huge impact on whether alcohol makes you aggressive
Drinking enough alcohol to become intoxicated increases aggression significantly in people who have one particular personality trait, according to new research. But people without that trait don't get any more aggressive when drunk than they would when they're sober. That trait is the ability to consider the future consequences of current actions.
NIH/National Institute on Alcohol Abuse and Alcoholism, National Center for Research Resources

Contact: Brad Bushman
Bushman.20@osu.edu
614-688-8779
Ohio State University

Public Release: 19-Dec-2011
Annals of Internal Medicine
What makes patients complex? Ask their primary care physicians
Being able to define and measure patient complexity has important implications for how care is organized, how physicians and health care systems are paid, and how resources are allocated. A team of Massachusetts General Hospital researchers have found that primary care physicians define patient complexity using a broader range of factors – including mental health, social factors and financial issues – than do commonly used approaches based only on diagnoses and prior costs.
National Institutes of Health, Partners Community HealthCare

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital

Public Release: 19-Dec-2011
Radiotherapy & Oncology
Wayne State study finds soybean compounds enhances effects of cancer radiotherapy
A Wayne State University researcher has shown that compounds found in soybeans can make radiation treatment of lung cancer tumors more effective while helping to preserve normal tissue.
National Institutes of Health

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research

Public Release: 19-Dec-2011
Journal of American College of Cardiology
Snipping key nerves may help life threatening heart rhythms
According to a new UCLA study, cutting key nerves to the heart that control the adrenaline-driven "flight or fight" stress response may help alleviate life-threatening ventricular arrhythmias. This is one of the first studies to assess the impact of performing this type of surgery on both sides of the heart to control arrhythmias, called a bilateral cardiac sympathetic denervation.
NIH/National Heart, Lung and Blood Institute

Contact: Rachel Champeau
rchampeau@mednet.ucla.edu
310-794-2270
University of California - Los Angeles Health Sciences

Public Release: 19-Dec-2011
Journal of Clinical Investigation
Blood pressure drug limits cigarette smoke-induced lung injury in mice
Chronic obstructive pulmonary disease is among the most common causes of death in the US. It is a smoking-related disease for which there are currently no disease-altering therapies. However, hope that one could be developed is now provided by new research using in a mouse model of lung disease caused by exposure to cigarette smoke.
National Institutes of Health, Grace Anne Dorney fund for tobacco-related research

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation

Public Release: 19-Dec-2011
Journal of Clinical Investigation
Potential concern about drugs in clinical trial
Drugs that enhance levels of small molecules derived naturally in the body from a major component of animal fats are currently in clinical trials for the treatment of high blood pressure and diabetes. Researchers have now generated data in mice that raise new concerns about the use of these drugs in humans.
National Institutes of Health, Stop and Shop Pediatric Brain Tumor Fund, C.J. Buckley Pediatric Brain Tumor Fund, Robert A. Welch Foundation

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation

Public Release: 19-Dec-2011
American Journal of Pathology
Georgetown researchers lead discovery expected to significantly change biomedical research
In a major step that could revolutionize biomedical research, scientists have discovered a way to keep normal cells as well as tumor cells taken from an individual cancer patient alive in the laboratory -- which previously had not been possible. Normal cells usually die in the lab after dividing only a few times, and many common cancers will not grow, unaltered, outside of the body.
National Institutes of Health, US Department of Defense, Georgetown Lombardi's Cancer Center, NIH/National Cancer Institute

Contact: Karen Mallet
km463@georgetown.edu
Georgetown University Medical Center

Public Release: 18-Dec-2011
Nature
Researchers create living 'neon signs' composed of millions of glowing bacteria
In an example of life imitating art, biologists and bioengineers at UC San Diego have created a living neon sign composed of millions of bacterial cells that periodically fluoresce in unison like blinking light bulbs. Their achievement was detailed in this week's advance online issue of the journal Nature.
NIH/National Institute of General Medical Sciences, National Institutes of Health

Contact: Kim McDonald
kmcdonald@ucsd.edu
858-534-7572
University of California - San Diego

Public Release: 18-Dec-2011
Nature Medicine
Regulatory enzyme overexpression may protect against neurodegeneration in Huntington's disease
Treatment that increases brain levels of an important regulatory enzyme may slow the loss of brain cells that characterizes Huntington's disease (HD) and other neurodegenerative disorders. A Massachusetts General Hospital-based research team found that increased expression of Sirt1, one of a family of enzymes called sirtuins, in the brain of a mouse model of HD protected against neurodegeneration. The investigators also identified a potential mechanism for this protective effect.
Cure Huntington's Disease Initiative, National Institutes of Health, Hereditary Disease Foundation, Glenn Foundation for Medical Research

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital

Public Release: 16-Dec-2011
Journal of Clinical Oncology
Childhood cancer drugs cure now, may cause problems later, UB research shows
Will a drug used to treat childhood acute lymphoblastic leukemia and other pediatric cancers cause heart problems later in life? UB associate professor of pharmaceutical sciences, Javier G. Blanco, Ph.D., who sees his work as a bridge between research and clinical practice, has focused recent efforts on trying to answer this question.
NIH/National Institute of General Medical Sciences, Lance Armstrong Foundation, Leukemia and Lymphoma Society

Contact: Sara Saldi
saldi@buffalo.edu
716-645-4593
University at Buffalo

Public Release: 16-Dec-2011
Chemical Engineering Journal
Novel device removes heavy metals from water
Engineers at Brown University have developed a system that cleanly and efficiently removes trace heavy metals from water. In experiments, the researchers showed the system reduced cadmium, copper, and nickel concentrations, returning contaminated water to near or below federally acceptable standards. The technique is scalable and has viable commercial applications, especially in the environmental remediation and metal recovery fields. Results appear in the Chemical Engineering Journal.
NIH/National Institute of Environmental Health Sciences, Brown University

Contact: Richard Lewis
Richard_Lewis@brown.edu
401-863-3766
Brown University

Public Release: 16-Dec-2011
Northwestern scientist gets mentoring award at White House
A Northwestern program that mentors urban minority high-school girls for college and careers in science and health received a mentoring award from President Obama. The program has expanded to other states.
National Institutes of Health

Contact: Marla Paul
marla-Paul@northwestern.edu
312-503-8928
Northwestern University

Public Release: 15-Dec-2011
Angewandte Chemie
Let's do the twist: Spiral proteins are efficient gene delivery agents
Clinical gene therapy may be one step closer, thanks to a new twist on an old class of molecules. University of Illinois researchers have demonstrated that short spiral-shaped proteins can efficiently deliver DNA segments to cells, with well-controlled toxicity. The team's helical polypeptides far exceeded random-coil polypeptide and even outstripped commercial agents in efficiency, even on some of the hardest cells to transfect: stem cells and fibroblast cells..
National Science Foundation, National Institutes of Health

Contact: Liz Ahlberg
eahlberg@illinois.edu
217-244-1073
University of Illinois at Urbana-Champaign

Public Release: 15-Dec-2011
Cancer Letters
Cancer from fetal exposure to carcinogens depends on dose, timing
The cancer-causing potential of fetal exposure to carcinogens can vary substantially, causing different types of problems much later in life depending on the stage of pregnancy when the fetus is exposed. The research sheds further light on the way in which toxic damage early in life can later manifest itself as cancer, due to "epigenetic" changes in cells.
National Institutes of Health

Contact: David Williams
david.williams@oregonstate.edu
541-737-3277
Oregon State University

Public Release: 15-Dec-2011
Orphanet Journal of Rare Diseases
Scientists discover second-oldest gene mutation
A new study has identified a gene mutation that researchers estimate dates back to 11,600 B.C., making it the second oldest human disease mutation known. The mutation was described in people of Arabic, Turkish and Jewish ancestry. It causes a rare, inherited vitamin B12 deficiency. The mutation originated in a single, prehistoric individual and was passed down to that individual's descendants. The discovery should permit reliable genetic diagnosis of suspected cases of Imerslund-Gräsbeck Syndrome.
NIH/National Cancer Institute

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Medical Center

Public Release: 15-Dec-2011
Journal of Cardiovascular Nursing
Heart failure study: Health-literate patients not always adept at managing care
A patient's education level is not a fail-safe predictor of how well they will manage symptoms related to complicated chronic diseases, such as heart failure, according to a Purdue University study.
Purdue/Regenstrief Center for Healthcare Engineering, NIH/National Institute on Aging, Purdue University

Contact: Amy Patterson Neubert
apatterson@purdue.edu
765-494-9723
Purdue University

Public Release: 15-Dec-2011
Genes & Immunity
Team pinpoints amino acid variation in immune response gene linked with ulcerative colitis
The association between the inflammatory bowel disease ulcerative colitis and a gene that makes certain cell surface proteins has been pinpointed to a variant amino acid in a crucial binding site that profoundly influences immune response to antigens, including gut bacteria, reports a team of researchers at the University of Pittsburgh, Cleveland Clinic, Carnegie Mellon University and Harvard Medical School. They published the findings today in the online version of Genes & Immunity.
National Institutes of Health, Crohn's and Colitis Foundation of America, US Department of Defense, Kenneth and Jennifer Rainin, Gerald and Nancy Goldberg, Victor and Ellen Cohn

Contact: Anita Srikameswaran
SrikamAV@upmc.edu
412-578-9193
University of Pittsburgh Schools of the Health Sciences

Public Release: 15-Dec-2011
Molecular Microbiology
F. nucleatum enables breaking bond on blood vessels to allow invaders in
A common oral bacteria, Fusobacterium nucleatum, acts like a key to open a door in human blood vessels and leads the way for it and other bacteria like Escherichia coli to invade the body through the blood and make people sick, according to dental researchers at Case Western Reserve University.
National Institutes of Health

Contact: Susan Griffith
susan.griffith@case.edu
216-368-1004
Case Western Reserve University

Showing releases 3051-3075 out of 3164.

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