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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3051-3075 out of 3609.

<< < 118 | 119 | 120 | 121 | 122 | 123 | 124 | 125 | 126 | 127 > >>

Public Release: 29-May-2014
Fertility and Sterility
Stress degrades sperm quality
Psychological stress is harmful to sperm and semen quality, affecting its concentration, appearance, and ability to fertilize an egg, according to a study led by researchers Columbia University's Mailman School of Public Health and Rutgers School of Public Health. Results are published online in the journal Fertility and Sterility.
NIH/National Institute of Environmental Health Sciences

Contact: Timothy S. Paul
Columbia University's Mailman School of Public Health

Public Release: 29-May-2014
Biology of Reproduction
Zinc deficiency before conception disrupts fetal development
Female mice deprived of dietary zinc for a relatively short time before conception experienced fertility and pregnancy problems and had smaller, less-developed fetuses than mice that ingested zinc during the same times, according to researchers in Penn State's College of Agricultural Sciences.
National Institutes of Health

Contact: A'ndrea Elyse Messer
Penn State

Public Release: 29-May-2014
Journal of American Society of Nephrology
Reduced kidney function associated with higher risk of renal and urothelial cancer
Researchers who investigated the level of kidney function and subsequent cancer risk in more than one million adults have found that reduced glomerular filtration rate -- a key measure of reduced kidney function and chronic kidney disease -- is an independent risk factor for renal and urothelial cancer but not other cancer types.
National Institutes of Health, NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Linda Aagard
University of Utah Health Sciences

Public Release: 29-May-2014
Unprecedented detail of intact neuronal receptor offers blueprint for drug developers
Biologists at Cold Spring Harbor Laboratory report today that they have succeeded in obtaining an unprecedented view of a type of brain-cell receptor that is implicated in a range of neurological illnesses, including Alzheimer's disease, Parkinson's disease, depression, schizophrenia, autism, and ischemic injuries associated with stroke. The team's atomic-level picture of the intact NMDA receptor should serve as template and guide for the design of therapeutic compounds.
National Institutes of Health, Mirus Research Award, Robertson Research Fund of Cold Spring Harbor Laboratory

Contact: Jaclyn Jansen
Cold Spring Harbor Laboratory

Public Release: 29-May-2014
Journal of the American Society of Nephrology
Reduced kidney function associated with higher risk of renal and urothelial cancer
A key measure of reduced kidney function and chronic kidney disease -- reduced glomerular filtration rate -- is an independent risk factor for renal and urothelial cancer, according to a study published online today in the Journal of the American Society of Nephrology.
National Institutes of Health

Contact: Cyrus Hedayati
Kaiser Permanente

Public Release: 29-May-2014
Cancer Cell
Melanoma of the eye caused by 2 gene mutations
Researchers at the University of California, San Diego School of Medicine have identified a therapeutic target for treating the most common form of eye cancer in adults. They have also, in experiments with mice, been able to slow eye tumor growth with an existing FDA-approved drug.
National Institutes of Health, California Institute for Regenerative Medicine

Contact: Scott LaFee
University of California - San Diego

Public Release: 29-May-2014
Cell Reports
Lost in translation?
In any animal's lifecycle, the shift from egg cell to embryo is a critical juncture that requires a remarkably dynamic process that ultimately transforms a differentiated, committed oocyte to a totipotent cell capable of giving rise to any cell type in the body. The lab of Whitehead Member Terry Orr-Weaver conducted perhaps the most comprehensive look yet at changes in translation and protein synthesis during a developmental change, using the oocyte-to-embryo transition in Drosophila as a model system.
National Institutes of Health, American Cancer Society, Alexander von Humboldt Foundation

Contact: Matt Fearer
Whitehead Institute for Biomedical Research

Public Release: 28-May-2014
Health Psychology
Negative social interactions increase hypertension risk in older adults
Keeping your friends close and your enemies closer may not be the best advice if you are 50 or older. New research from Carnegie Mellon University's Rodlescia Sneed and Sheldon Cohen shows that unpleasant or demanding interpersonal encounters increase hypertension risk among older adults. Published in the American Psychological Association's Health Psychology Journal, the study provides some of the first concrete evidence that negative social interactions not only influence psychological well-being but also physical health -- in this case, blood pressure levels.
NIH/National Center for Complementary and Alternative Medicine

Contact: Shilo Rea
Carnegie Mellon University

Public Release: 28-May-2014
Cancer Cell
International collaboration highlights new mechanism explaining how cancer cells spread
UT Southwestern Medical Center cancer researchers have identified a protein critical to the spread of deadly cancer cells and determined how it works, paving the way for potential use in diagnosis and eventually possible therapeutic drugs to halt or slow the spread of cancer.
National Institutes of Health, China Postdoctoral Science Foundation

Contact: Russell Rian
UT Southwestern Medical Center

Public Release: 28-May-2014
Annals of Surgical Oncology
NYU researchers pilot educational and behavioral program to reduce lymphedema risk
NYU researchers conducted a pilot study to evaluate a patient-centered educational and behavioral self-care program called The Optimal Lymph Flow. The goals of the program were to promote lymph flow and optimize BMI over a 12-month period after breast cancer surgery. Findings offer initial evidence in support of a shift in the focus of lymphedema care away from treatment and toward proactive risk reduction.
Avon Foundation, NIH/National Cancer Institute

Contact: christopher james
New York University

Public Release: 28-May-2014
Journal of Clinical Psychiatry
PTSD treatment cost-effective when patients given choice
A cost-analysis of post-traumatic stress disorder treatments shows that letting patients choose their course of treatment -- either psychotherapy or medication -- is less expensive than assigning a treatment and provides a higher quality of life for patients.
NIH/National Institute of Mental Health, American Association of Colleges of Pharmacy

Contact: Molly McElroy
University of Washington

Public Release: 28-May-2014
Uncovering clues to the genetic cause of schizophrenia
The overall number and nature of mutations -- rather than the presence of any single mutation -- influences an individual's risk of developing schizophrenia, as well as its severity, according to a discovery by Columbia University Medical Center researchers published in the latest issue of Neuron. The findings could have important implications for the early detection and treatment of schizophrenia.
NIH/National Institute of Mental Health

Contact: Lucky Tran
Columbia University Medical Center

Public Release: 28-May-2014
Sexually Transmitted Infections
In Africa, STI testing could boost HIV prevention
Sexually transmitted infections can make HIV transmission more likely, undermining the prevention benefit of HIV treatment. A new study of HIV-positive patients in Cape Town, South Africa, found that the prevalence of such co-infections was much higher before beginning HIV treatment. Testing for and treating STIs and HIV together could therefore improve HIV prevention.
National Institutes of Health

Contact: David Orenstein
Brown University

Public Release: 28-May-2014
'Nanodaisies' deliver drug cocktail to cancer cells
Biomedical engineering researchers have developed daisy-shaped, nanoscale structures that are made predominantly of anti-cancer drugs and are capable of introducing a 'cocktail' of multiple drugs into cancer cells.
National Institutes of Health

Contact: Matt Shipman
North Carolina State University

Public Release: 28-May-2014
Major discovery on the mechanism of drug resistance in leukemia and other cancers
A mechanism that enables the development of resistance to acute myeloid leukemia anticancer drugs, thereby leading to relapse, has been identified by Kathy Borden of the University of Montreal's Institute for Research in Immunology and Cancer and her collaborators.
National Institutes of Health, Leukemia and Lymphoma Society, Pharmascience Inc., IRICoR, Cancer Research Chairs, Natural Sciences and Engineering Research Council of Canada

Contact: William Raillant-Clark
University of Montreal

Public Release: 28-May-2014
Extensive cataloging of human proteins uncovers 193 never known to exist
Striving for the protein equivalent of the Human Genome Project, an international team of researchers has created an initial catalog of the human 'proteome,' or all of the proteins in the human body. In total, using 30 different human tissues, the team identified proteins encoded by 17,294 genes, which is about 84 percent of all of the genes in the human genome predicted to encode proteins.
NIH/National Institute of General Medical Sciences, NIH/National Cancer Institute, NIH/National Heart, Lung, and Blood Institute, and others

Contact: Catherine Kolf
Johns Hopkins Medicine

Public Release: 28-May-2014
JAMA Surgery
Black trauma patients 65 and older more likely to survive than white counterparts
In a finding that runs counter to most health disparities research, Johns Hopkins researchers say that while younger black trauma patients are significantly more likely than whites to die from their injuries, black trauma patients over the age of 65 are 20 percent less likely to do so.
NIH/National Institute of General Medical Sciences, and others

Contact: Stephanie Desmon
Johns Hopkins Medicine

Public Release: 27-May-2014
American Journal of Human Genetics
Quantity, not quality: Risk of sudden cardiac death tied to protein overproduction
A genetic variant linked to sudden cardiac death leads to protein overproduction in heart cells, Johns Hopkins scientists report. Unlike many known disease-linked variants, this one lies not in a gene but in so-called noncoding DNA, a growing focus of disease research. The discovery also adds to scientific understanding of the causes of sudden cardiac death and of possible ways to prevent it, the researchers say.
NIH/National Heart, Lung, and Blood Institute, Donald W. Reynolds Foundation

Contact: Shawna Williams
Johns Hopkins Medicine

Public Release: 27-May-2014
Medical Care
More access to health care may lead to unnecessary mammograms
Researchers have concluded that providing better access to health care may lead to the overuse of mammograms for women who regularly see a primary care physician and who have a limited life expectancy. The cautionary note from researchers at the University of Texas Medical Branch at Galveston is that screening women in this category could subject them 'to greater risks of physical, emotional and economic suffering.'
Cancer Prevention Research Institute of Texas, National Institutes of Health

Contact: Raul Reyes
University of Texas Medical Branch at Galveston

Public Release: 27-May-2014
Developmental Cell
UCI researchers identify new functional roles on cell surfaces for estrogen
A discovery by UC Irvine endocrinologists about the importance of cell surface receptors for estrogen has the potential to change how researchers view the hormone's role in normal organ development and function.
National Institutes of Health, Department of Veterans Affairs

Contact: Tom Vasich
University of California - Irvine

Public Release: 27-May-2014
New University of Colorado study illuminates how cancer-killing gene may actually work
Scientists armed with a supercomputer and a vast trove of newly collected data on the body's most potent "tumor suppressor" gene have created the best map yet of how the gene works, an accomplishment that could lead to new techniques for fighting cancers, which are adept at disabling the gene in order to thrive.
Howard Hughes Medical Institute, National Institutes of Health, National Science Foundation

Contact: Garth Sundem
University of Colorado Denver

Public Release: 27-May-2014
Proceedings of the National Academy of Sciences
Two new possible drug targets for triple negative breast cancer
The suppression of two genes reduce breast cancer tumor formation and metastasis by interfering with blood vessel formation and recruitment, report scientists in the Proceedings of the National Academy of Sciences. The findings may help medical researchers identify effective drug targets for triple negative breast cancer, or TNBC.
National Institutes of Health, Golfers Against Cancer, Breast Cancer Research Foundation

Contact: David Bricker
Houston Methodist

Public Release: 27-May-2014
Critical Care Medicine
Steroids prescribed in the ICU linked to delirium
New Johns Hopkins research suggests that critically ill patients receiving steroids in a hospital's intensive care unit (ICU) are significantly more likely to develop delirium. Results of their research, they say, suggest minimizing the use of steroids could reduce delirium in the ICU.
NIH/National Heart, Lung and Blood Institute

Contact: Stephanie Desmon
Johns Hopkins Medicine

Public Release: 27-May-2014
Tobacco Control
Seeing e-cigarette use encourages young adult tobacco users to light up
Seeing people use electronic cigarettes increases the urge to smoke among regular combustible cigarettes users, according to a new study of young adult smokers. This elevated desire is as strong as when observing someone smoking a regular cigarette, report scientists from the University of Chicago online, May 21, in Tobacco Control. The study is the first to investigate the behavioral effects of exposure to e-cigarette use in a controlled setting.
NIH/National Cancer Institute, NIH/National Institute on Alcohol Abuse and Alcoholism, NIH/National Institute on Drug Abuse

Contact: Kevin Jiang
University of Chicago Medical Center

Public Release: 27-May-2014
Journal of Clinical Investigation
Disturbance in blood flow leads to epigenetic changes and atherosclerosis
Disturbed patterns of blood flow induce lasting epigenetic changes to genes in the cells that line blood vessels, and those changes contribute to atherosclerosis, researchers have found. The findings suggest why the protective effects of good blood flow patterns, which aerobic exercise promotes, can persist over time.
NIH/National Heart, Lung, and Blood Institute

Contact: Quinn Eastman
Emory Health Sciences

Showing releases 3051-3075 out of 3609.

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