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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 3051-3075 out of 3508.

<< < 118 | 119 | 120 | 121 | 122 | 123 | 124 | 125 | 126 | 127 > >>

Public Release: 11-Dec-2013
Science Translational Medicine
Dietary amino acids relieve sleep problems after traumatic brain injury in animals
Scientists who fed a cocktail of key amino acids to mice improved sleep disturbances caused by brain injuries in the animals. These new findings suggest a potential dietary treatment for millions of people affected by traumatic brain injury -- a condition that is currently untreatable.
National Institutes of Health

Contact: John Ascenzi
ascenzi@email.chop.edu
267-426-6055
Children's Hospital of Philadelphia

Public Release: 11-Dec-2013
2013 CTRC-AACR San Antonio Breast Cancer Symposium
Exercise protects against aggressive breast cancer in black women
A nearly 20-year observational study involving more than 44,700 black women nationwide found that regular vigorous exercise offers significant protection against development of the most aggressive subtypes of breast cancer. The findings from the Black Women's Health Study are being presented Wednesday, Dec. 11 at the 2013 San Antonio Breast Cancer Symposium.
NIH/National Cancer Institute

Contact: Karen Teber
km463@georgetown.edu
Georgetown University Medical Center

Public Release: 10-Dec-2013
Human Genetics
Scientists identify more powerful approach to analyze melanoma's genetic causes
There may be a better way to analyze the genetic causes of cutaneous melanoma according to a study published in Human Genetics conducted by researchers Yale and Dartmouth. A statistical analysis using the natural and orthogonal interaction model showed increased power over existing approaches for detecting genetic effects and interactions when applied to the genome-wide melanoma dataset.
National Institutes of Health

Contact: Donna Dubuc
Donna.M.Dubuc@Dartmouth.edu
603-653-3615
The Geisel School of Medicine at Dartmouth

Public Release: 10-Dec-2013
Nursing Research
Motivating healthy adults to be more physically active improves their cardiorespiratory fitness
Fewer than half of adults in the United States meet the recommended physical activity guidelines set by the Centers for Disease Control and Prevention. Often physical inactivity may be associated with overweight and obese individuals, but even healthy, normal-weight Americans sometimes fail to meet physical activity guidelines. Now, University of Missouri researchers have found that simply encouraging healthy adults to be more physically active can improve their cardiorespiratory fitness.
National Institutes of Health, NIH/National Institute of Nursing Research

Contact: Jesslyn Chew
ChewJ@missouri.edu
573-882-8353
University of Missouri-Columbia

Public Release: 10-Dec-2013
Osteoporosis International
Low vitamin B12 levels increase the risk of fractures in older men
Older men who have low levels of vitamin B12 have a higher risk of having fractures. These are the findings of researchers at the Sahlgrenska Academy as a part of an international study of a total of 1,000 older men.
National Institutes of Health

Contact: Catharina Lewerin
Catharina.lewerin@vgregion.se
University of Gothenburg

Public Release: 10-Dec-2013
Prevalence of chronic fatigue syndrome in youth is focus of Chicago-based study
The prevalence of chronic fatigue syndrome in children and the significant impairment it causes to their physical functioning, school attendance and performance, and extracurricular activities, are at the root of a new Chicago-based study led by DePaul University psychologist Leonard A. Jason.
NIH/Eunice Kennedy Shriver National Institute of Children Health and Human Development

Contact: Carol Hughes
chughe23@depaul.edu
312-362-8592
DePaul University

Public Release: 10-Dec-2013
Cell Metabolism
SIRT5 regulation has dramatic effect on mitochondrial metabolism
The Sirtuin family of protein deacylases has received considerable attention due to its links to longevity, diabetes, cancer, and metabolic regulation. In a new study researchers identified widespread regulation of proteins involved in metabolism by the mitochondrial sirtuin, SIRT5. Using a novel method scientists identified hundreds of proteins that undergo modification by lysine succinylation and its subsequent regulation by SIRT5. These findings have widespread implications for understanding metabolic function in both normal and disease states.
National Institutes of Health

Contact: Kris Rebillot
krebillot@buckinstitute.org
415-209-2080
Buck Institute for Age Research

Public Release: 10-Dec-2013
55th American Society of Hematology Annual Meeting
Less painful drug delivery for pediatric leukemia patients is safe, effective
Children with acute lymphoblastic leukemia, the most common form of pediatric cancer, can safely receive intravenous infusions of a reformulated mainstay of chemotherapy that has been delivered via painful intramuscular injection for more than 40 years, research suggests.
NIH/National Cancer Institute, Enzon Pharmaceuticals

Contact: Irene Sege
irene.sege@childrens.harvard.edu
617-919-3110
Dana-Farber Cancer Institute

Public Release: 10-Dec-2013
American Journal of Preventive Medicine
Strong state alcohol policies protective against binge drinking
According to a new study, a novel composite measure consisting of 29 alcohol policies demonstrates that a strong alcohol policy environment is a protective factor against binge drinking in the U.S. The study was led by researchers at the Boston University Schools of Medicine and Public Health and Boston Medical Center, and is published in the current issue of the American Journal of Preventive Medicine.
National Institutes of Health

Contact: Gina DiGravio
gina.digravio@bmc.org
617-638-8480
Boston University Medical Center

Public Release: 9-Dec-2013
Cancer Cell
Gene sequencing project finds family of drugs with promise for treating childhood tumor
Drugs that enhance a process called oxidative stress were found to kill rhabdomyosarcoma tumor cells growing in the laboratory and possibly bolstered the effectiveness of chemotherapy against this aggressive tumor of muscle and other soft tissue. The findings are the latest from the St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project and appear in the Dec. 9 edition of the scientific journal Cancer Cell.
Pediatric Cancer Genome Project, Kay Jewelers, NIH/National Cancer Institute, Howard Hughes Medical Institute, Tully Family Foundation, American-Lebanese-Syrian Associated Charities

Contact: Carrie Strehlau
carrie.strehlau@stjude.org
901-595-2295
St. Jude Children's Research Hospital

Public Release: 9-Dec-2013
Proceedings of the National Academy of Sciences
OHSU researchers develop new drug approach that could lead to cures for wide range of diseases
A team led by a longtime Oregon Health & Science University researcher has demonstrated in mice what could be a revolutionary new technique to cure a wide range of human diseases -- from cystic fibrosis to cataracts to Alzheimer's disease -- that are caused by "misfolded" protein molecules.
National Institutes of Health, Ben F. Love Endowment, American Heart Association

Contact: Todd Murphy
murphyt@ohsu.edu
503-494-8231
Oregon Health & Science University

Public Release: 9-Dec-2013
Proceedings of the National Academy of Sciences
New sensor tracks zinc in cells
Shifts in zinc's location could be exploited for early diagnosis of prostate cancer.
NIH/National Institute of General Medical Sciences

Contact: Andrew Carleen
acarleen@mit.edu
617-253-1682
Massachusetts Institute of Technology

Public Release: 9-Dec-2013
Obesity
Kids movies send mixed messages about eating habits and obesity
Many of the most popular children's movies from recent years feature both "obesogenic" behaviors and weight-related stigmatizing content, a study by University of North Carolina at Chapel Hill researchers finds.
N.C. Children's Promise, National Institutes of Health

Contact: Tom Hughes
tahughes@unch.unc.edu
919-966-6047
University of North Carolina Health Care

Public Release: 9-Dec-2013
Grant supports creation of patient-derived stem cell lines for Alzheimer's research
Researchers at UC Irvine's Institute for Memory Impairments and Neurological Disorders have received a two-year, $600,000 grant from the National Institute on Aging to develop and study patient-derived stem cell lines.
NIH/National Institute on Aging

Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine

Public Release: 9-Dec-2013
Biological Psychiatry
How a concussion can lead to depression years later
A head injury can lead immune-system brain cells to go on "high alert" and overreact to later immune challenges by becoming excessively inflammatory -- a condition linked with depressive complications, a new animal study suggests.
NIH/National Institute on Aging, Howard Hughes Medical Institute

Contact: Jonathan Godbout
Jonathan.Godbout@osumc.edu
614-293-3456
Ohio State University

Public Release: 9-Dec-2013
Proceedings of the National Academy of Sciences
The smoking gun: Fish brains and nicotine
In researching neural pathways, it helps to establish an analogous relationship between a region of the human brain and the brains of more-easily studied animal species. New work from a team led by Carnegie's Marnie Halpern hones in on one particular region of the zebrafish brain that could help us understand the circuitry underlying nicotine addiction.
European Molecular Biology Organization, University of Virginia, National Institutes of Health

Contact: Marnie Halpern
halpern@ciwemb.edu
410-246-3018
Carnegie Institution

Public Release: 9-Dec-2013
Biomaterials
Innovative drug-dispensing contact lens delivers glaucoma medication continuously for a month
Researchers at Massachusetts Eye and Ear/Harvard Medical School Department of Ophthalmology, Boston Children's Hospital, and the Massachusetts Institute of Technology are one step closer to an eye drop-free reality with the development of a drug-eluting contact lens designed for prolonged delivery of latanoprost, a common drug used for the treatment of glaucoma, the leading cause of irreversible blindness worldwide.
NIH/National Eye Institute, Massachusetts Eye Lions Research Fund, New England Cornea Transplant Fund, NIH/National Institute of General Medical Sciences

Contact: Mary Leach
Mary_Leach@meei.harvard.edu
617-573-4170
Massachusetts Eye and Ear Infirmary

Public Release: 9-Dec-2013
JAMA Pediatrics
Communities across US reduce teen smoking, drinking, violence and crime
Fewer high school students across the US started drinking alcohol, smoking cigarettes, committing crimes and engaging in violence before graduation when their towns used the Communities That Care prevention system during the teens' middle school years. A University of Washington study found that the positive influence of this community-led system was sustained through high school.
National Institutes of Health

Contact: Molly McElroy
mollywmc@uw.edu
206-543-2580
University of Washington

Public Release: 9-Dec-2013
Proceedings of the National Academy of Sciences
How 'sunshine vitamin' D may be helpful in fighting multiple sclerosis
In mice with a rodent form of multiple sclerosis, vitamin D appears to block damage-causing immune cells from migrating to the central nervous system, offering a potential explanation for why the so-called "sunshine vitamin" may prevent or ease symptoms of the neurodegenerative disease, according to results of a study at Johns Hopkins.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Stephanie Desmon
sdesmon1@jhmi.edu
410-955-8665
Johns Hopkins Medicine

Public Release: 9-Dec-2013
Journal of Clinical Investigation
Choloroquine reduces formation of bone resorbing cells in murine osteoporosis
In this issue of the Journal of Clinical Investigation, Brendan Boyce and colleagues at the University of Rochester evaluated the role of TNF receptor–associated receptor 3 in promoting osteoclast formation.
NIH/National Institute for Arthritis, Musculoskeletal and Skin Diseases

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 9-Dec-2013
Journal of Clinical Investigation
Breast cancer prognosis associated with oncometabolite accumulation
In this issue of the Journal of Clinical Investigation Stefan Ambs and colleagues at the National Cancer Institute discovered an association between the oncometabolite 2-hydroxyglutarate levels, DNA methylation patterns, and breast cancer prognosis.
National Institutes of Health, NIH/National Cancer Institute, CCR

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 8-Dec-2013
52nd Annual Meeting of the American College of Neuropsychopharmacology
Neuropsychopharmacology
Aging and gene expression -- possible links to autism and schizophrenia in offspring
Advanced paternal age has been associated with greater risk for psychiatric disorders, such as schizophrenia and autism. With an increase in paternal age, there is a greater frequency of certain types of mutations that contribute to these disorders in offspring. Recent research, however, looks beyond the genetic code to "epigenetic effects," which do not involve changes in the genes themselves, but rather in how they are expressed to determine one's characteristics.
NIH/National Institute of Mental Health, Simon Foundation, Brain and Behavior Research Foundation/NARSAD Young Investigator Award

Contact: Laura Hill
lhill@acnp.org
American College of Neuropsychopharmacology

Public Release: 8-Dec-2013
Nature
From common colds to deadly lung diseases, 1 protein plays key role
An international team of researchers has zeroed in on a protein that plays a key role in many lung-related ailments, from seasonal coughing and hacking to more serious diseases such as MRSA infections and cystic fibrosis. The finding advances knowledge about this range of illnesses and may point the way to eventually being able to prevent infections such as MRSA. The key protein is called MUC5B.
National Institutes of Health

Contact: Dan Meyers
dan.meyers@ucdenver.edu
University of Colorado Denver

Public Release: 8-Dec-2013
55th American Society of Hematology Annual Meeting
Flipping a gene switch reactivates fetal hemoglobin, may reverse sickle cell disease
Hematology researchers have manipulated key biological events in adult blood cells to produce a form of hemoglobin normally absent after the newborn period. Because fetal hemoglobin is unaffected by the genetic defect in sickle cell disease, these cell culture findings may open the door to a new therapy for the debilitating blood disorder.
National Institutes of Health, American Heart Association

Contact: Rachel Salis-Silverman
salis@email.chop.edu
267-970-3685
Children's Hospital of Philadelphia

Public Release: 8-Dec-2013
Nature Neuroscience
Extensive variability in olfactory receptors influences human odor perception
Researchers from the Monell Center and collaborating institutions have found that as much as 30 percent of the large array of human olfactory receptor differs between any two individuals. This substantial variation is in turn reflected by variability in how each person perceives odors.
NIH/National Institute on Deafness and Other Communication Disorders

Contact: Leslie Stein
stein@monell.org
267-519-4707
Monell Chemical Senses Center

Showing releases 3051-3075 out of 3508.

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