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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3051-3075 out of 3574.

<< < 118 | 119 | 120 | 121 | 122 | 123 | 124 | 125 | 126 | 127 > >>

Public Release: 24-Mar-2014
Nature Methods
New technique for identifying gene-enhancers
Berkeley Lab researchers led the development of a new technique for identifying gene enhancers -- sequences of DNA that act to amplify the expression of a specific gene -- in the genomes of humans and other mammals. Called SIF-seq, this new technique complements existing genomic tools, such as ChIP-seq, and offers additional benefits.
National Institutes of Health

Contact: Lynn Yarris
DOE/Lawrence Berkeley National Laboratory

Public Release: 24-Mar-2014
Proceedings of the National Academy of Sciences
Obamacare: 42 percent of Americans can't explain a deductible
The week before open enrollment closes for new health care exchanges, a study shows that those who might potentially benefit the most from the Affordable Care Act -- including those earning near the federal poverty level -- are also the most clueless about health care policies.
NIH/National Institute on Aging

Contact: Suzanne Wu
University of Southern California

Public Release: 24-Mar-2014
Proceedings of the National Academy of Sciences
Protein plays key role in infection by oral pathogen
Scientists at Forsyth, along with a colleague from Northwestern University, have discovered that the protein, Transgultaminase 2 is a key component in the process of gum disease.
National Institutes of Health

Contact: Jennifer Kelly
Forsyth Institute

Public Release: 24-Mar-2014
Circulation Research
Protein called YAP gives blood vessels strength, shape
A protein known to promote cancer appears to give the blood vessels strength and shape, researchers report.
National Institutes of Health

Contact: Toni Baker
Medical College of Georgia at Georgia Regents University

Public Release: 24-Mar-2014
University of Cincinnati to study impact of blood 'microparticles' in inflammation, injury
University of Cincinnati trauma and critical care researcher Timothy Pritts, M.D., Ph.D., has received a National Institutes of Health grant to better understand how 'microparticles' in stored blood can contribute to inflammation and injury after resuscitation from traumatic injury. The five-year, $1.5 million R01 research award from the National Institute of General Medical Sciences will allow Pritts' team to investigate the nature of microparticles that bud off of damaged or active blood cells during storage.
National Institutes of Health, NIH/National Institute of General Medical Sciences

Contact: Katy Cosse
University of Cincinnati Academic Health Center

Public Release: 24-Mar-2014
Proceedings of the National Academy of Sciences
For neurons in the brain, identity can be used to predict location
There are many types of neurons of neurons, defined largely by the patterns of genes they use, and they 'live' in distinct brain regions. But researchers do not yet have a comprehensive understanding of these neuronal types and how they are distributed in the brain. A team of scientists at Cold Spring Harbor Laboratory describes a new mathematical model that combines large data sets to predict where different types of cells are located within the brain.
NIH/National Institute on Drug Abuse

Contact: Jaclyn Jansen
Cold Spring Harbor Laboratory

Public Release: 24-Mar-2014
Annals of Rheumatic Diseases
Study finds gout drug may reduce risk of death
In a recently to be published study in Annals of the Rheumatic Diseases, researchers have found the use of the drug allopurinol was associated with a reduced risk of death in hyperuricemic (gout) patients. The study, the first in a general population, has found the overall benefit of allopurinol on survival may outweigh the impact of rare serious adverse effects.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, Arthritis Foundation

Contact: Gina DiGravio
Boston University Medical Center

Public Release: 24-Mar-2014
Molecular Psychiatry
Diabetes drug shows promise in reducing Alzheimer's disease in an experimental model
Researchers from Boston University School of Medicine have found that the diabetic drug, pramlintide, reduces amyloid-beta peptides, a major component of Alzheimer's disease in the brain and improves learning and memory in two experimental Alzheimer's disease models. These findings, which appear online in Molecular Psychiatry, also found Alzheimer's disease patients have a lower level of amylin in blood compared to those without this disease. These results may provide a new avenue for both treatment and diagnosis of Alzheimer's disease.
NIH/National Institute on Aging, Ignition Award, Boston University Alzheimer's Disease Center pilot grant

Contact: Gina DiGravio
Boston University Medical Center

Public Release: 24-Mar-2014
Proceedings of the National Academy of Sciences
Scientists find a molecular clue to the complex mystery of auxin signaling in plants
Plants fine-tune the response of their cells to the potent plant hormone auxin by means of large families of proteins that either step on the gas or put on the brake in auxin's presence. Scientists at Washington University have learned that one of these proteins, a transcription factor, has an interaction region that, like a button magne, has a positive and negative face. Because of this domain, the protein can bind two other proteins or even chains of proteins arranged back to front.
National Science Foundation, National Institutes of Health

Contact: Diana Lutz
Washington University in St. Louis

Public Release: 24-Mar-2014
Journal of Clinical Oncology
Oncologists differ widely on offering cancer gene testing, study finds
Many cancer researchers believe that cutting-edge advances in genomics will pave the way for personalized or 'precision' cancer medicine for all patients in the near future. A new study by researchers at Dana-Farber Cancer Institute, however, suggest that not all doctors are ready to embrace tests that look for hundreds of DNA changes in patients' tumor samples, while others plan to offer this type of cancer gene testing to most of their patients. The findings are published in the Journal of Clinical Oncology.
NIH/National Human Genome Research Institute, American Cancer Society

Contact: Anne Doerr
Dana-Farber Cancer Institute

Public Release: 24-Mar-2014
Proceedings of the National Academy of Sciences
Deletion of FAT10 gene reduces body fat, slows down aging in mice
A single gene appears to play a crucial role in coordinating the immune system and metabolism, and deleting the gene in mice reduces body fat and extends lifespan, according to new research by scientists at the Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University and Yale University School of Medicine.
National Institutes of Health

Contact: Andrea Grossman
Tufts University, Health Sciences Campus

Public Release: 24-Mar-2014
Integrating mental health services in pediatric practices feasible, effective, Pitt finds
Brief behavioral and mental health programs for children can be effectively provided within pediatric practices as an alternative to being referred to a community specialist, University of Pittsburgh Schools of the Health Sciences researchers found in a National Institutes of Health-funded randomized trial.
NIH/National Institute of Mental Health

Contact: Allison Hydzik
University of Pittsburgh Schools of the Health Sciences

Public Release: 24-Mar-2014
Human Reproduction
Study: Stress impacts ability to get pregnant
Women who have trouble getting pregnant may be under too much stress, according to a new study in the journal of Human Reproduction. According to researchers at the Ohio State University Wexner Medical Center, women who had the highest levels of stress actually took 29 percent longer to get pregnant compared to other women, and their risk of infertility doubled.
NIH/National Institute of Child Health and Human Development

Contact: Allison Wenger
Ohio State University Wexner Medical Center

Public Release: 24-Mar-2014
Journal of Cell Biology
How developing sperm stick to the right path
The process of producing high-quality, fertile sperm requires many steps. Researchers show how the transcription factor p73 promotes this process by regulating the adhesions between developing sperm and their support cells.
NIH/National Cancer Institute, Deutsche Krebshilfe

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 24-Mar-2014
Journal of Studies on Alcohol and Drugs
Alcohol's role in traffic deaths vastly underreported: Study
It's no secret that drinking and driving can be a deadly mix. But the role of alcohol in US traffic deaths may be substantially underreported on death certificates, according to a study in the March issue of the Journal of Studies on Alcohol and Drugs.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: John Bowersox
Journal of Studies on Alcohol and Drugs

Public Release: 23-Mar-2014
Nature Chemical Biology
Shifting evolution into reverse promises cheaper, greener way to make new drugs
A proof-of-concept experiment has shown that, by shifting evolution into reverse, it may be possible to use 'green chemistry' to make a number of costly synthetic drugs as easily and cheaply as brewing beer.
National Science Foundation, National Institutes of Health, US Department of Energy

Contact: David Salisbury
Vanderbilt University

Public Release: 23-Mar-2014
Nature Materials
MIT engineers design 'living materials'
Hybrid materials combine bacterial cells with nonliving elements that can conduct electricity or emit light.
Office of Naval Research, US Army Research Office, National Science Foundation, Hertz Foundation, US Department of Defense, National Institutes of Health, Presidential Early Career Awrd for Scientists & Engineers

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 23-Mar-2014
Nature Structural & Molecular Biology
Mass. General study identifies path to safer drugs for heart disease, cancer
Massachusetts General Hospital investigators may have found a way to solve a problem that has plagued a group of drugs called ligand-mimicking integrin inhibitors, which have the potential to treat conditions ranging from heart attacks to cancer metastasis.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Sue McGreevey
Massachusetts General Hospital

Public Release: 21-Mar-2014
Journal of Clinical Oncology
Keck Medicine of USC research may point to better predictor of prostate cancer survival
New research by USC Norris Comprehensive Cancer Center scientists demonstrates that measuring circulating tumor cells -- the cells that spread cancer through the body -- may be a better predictor of patient survival than the prostate-specific antigen.
NIH/National Cancer Institute, Hope Foundation

Contact: Leslie Ridgeway
University of Southern California - Health Sciences

Public Release: 21-Mar-2014
With a few finger taps, draw genetic pedigrees at point of care with new app
Long used in genetic medicine, pedigrees are diagrams that show how inherited diseases may recur in a particular family. A new app adds a digital spin, letting clinicians create pedigrees with a few finger taps during a patient encounter.
NIH/National Human Genome Research Institute

Contact: John Ascenzi
Children's Hospital of Philadelphia

Public Release: 21-Mar-2014
Journal of Dental Research
Gene expression signature reveals new way to classify gum disease
Researchers have devised a new system for classifying periodontal disease based on the genetic signature of affected tissue, rather than on clinical signs and symptoms. The new classification system, the first of its kind, may allow for earlier detection and more individualized treatment of severe periodontitis, before loss of teeth and supportive bone occurs. The findings were published recently in the online edition of the Journal of Dental Research.
NIH/National Institute of Dental and Craniofacial Research, National Institutes of Health, Colgate-Palmolive

Contact: Karin Eskenazi
Columbia University Medical Center

Public Release: 20-Mar-2014
Stem Cell Reports
Stem cell study finds source of earliest blood cells during development
In a study published April 8 in Stem Cell Reports, Matthew Inlay of the Sue & Bill Gross Stem Cell Research Center and Stanford University colleagues created novel cell assays that identified the earliest arising HSC precursors based on their ability to generate all major blood cell types (red blood cells, platelets and immune cells).
National Institutes of Health

Contact: Matthew Inlay
University of California - Irvine

Public Release: 20-Mar-2014
Cell Reports
Surprising new way to kill cancer cells
Scientists have demonstrated that cancer cells -- and not normal cells -- can be killed by eliminating either the FAS receptor, also known as CD95, or its binding component, CD95 ligand. The discovery seems counterintuitive because CD95 has previously been defined as a tumor suppressor, scientists said.
NIH/National Cancer Institute

Contact: Marla Paul
Northwestern University

Public Release: 20-Mar-2014
Einstein helps establish $28 million consortium to find ebola treatment
Albert Einstein College of Medicine helps establish new $28 million consortium to find antibody treatments for Ebola and other viruses.
National Institutes of Health

Contact: Deirdre Branley
Albert Einstein College of Medicine

Public Release: 20-Mar-2014
Journal of Clinical Investigation
Genome-wide association studies mislead on cardiac arrhythmia risk gene
Although genome-wide association studies have linked DNA variants in the gene SCN10A with increased risk for cardiac arrhythmia, efforts to determine its role have been unproductive. Now, scientists have discovered that these SCN10A variants regulate a different gene, SCN5A, which appears to be the primary gene responsible for cardiac arrhythmia risk. The SCN10A gene itself plays only a minimal role in the heart, according to the study, published in the Journal of Clinical Investigation.
National Institutes of Health

Contact: Kevin Jiang
University of Chicago Medical Center

Showing releases 3051-3075 out of 3574.

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