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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3051-3075 out of 3575.

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Public Release: 24-Feb-2014
Advanced Functional Materials
New biological scaffold offers promising foundation for engineered tissues
Engineered tissues like artificial skin begin with a scaffold for cells to grow on. Now a team led by Michigan Technological University's Feng Zhao has coaxed cells called fibroblasts into creating a scaffold that mimics the body's own internal matrix, and in early tests, cells seem happy to set up residence.
National Institutes of Health, Flight Attendant Medical Research Institute

Contact: Marcia Goodrich
Michigan Technological University

Public Release: 24-Feb-2014
Proceedings of the National Academy of Sciences
Marine algae can sense the rainbow
A new study published in Proceedings of the National Academy of Sciences has shown for the first time that several types of aquatic algae can detect orange, green and blue light.
US Department of Agriculture, Gordon and Betty Moore Foundation, National Institutes of Health, Packard Foundation, and others

Contact: Lindsay Jolivet
Canadian Institute for Advanced Research

Public Release: 24-Feb-2014
JAMA Internal Medicine
For older hypertension patients, an unwelcome tradeoff
Medications used by many older people to control their blood pressure also increase the risk of serious fall injuries by 30 percent to 40 percent -- injuries that have a similar effect on mortality and functional loss as the strokes and heart attacks the blood pressure drugs are meant to prevent -- according to a new study by Yale School of Medicine researchers in the Feb. 24 issue of JAMA Internal Medicine.
NIH/National Institute on Aging

Contact: Karen N. Peart
Yale University

Public Release: 24-Feb-2014
Developmental Cell
Like mom or dad? Some cells randomly express one parent's version of a gene over the other
Both of our parents contribute one copy of a gene to our genetic makeup. Generally, both copies are switched on or off together. Occasionally, a cell will begin to use of one copy over the other. Today, a team of researchers at CSHL shows that this random phenomenon is far more likely to be found in mature, developed cell types than in their stem cell precursors, offering an unexpected glimpse of variability in gene expression.
NIH/National Institute of General Medical Sciences, NIH/National Cancer Institute

Contact: Jaclyn Jansen
Cold Spring Harbor Laboratory

Public Release: 24-Feb-2014
Journal of Clinical Investigation
Blocking autophagy with malaria drug may help overcome resistance to melanoma BRAF drugs
A new preclinical study published online ahead of print in the Journal of Clinical Investigation from Penn Medicine researchers found that the root of BRAF drug resistance may lie in a never-before-seen autophagy mechanism induced by the BRAF inhibitors vermurafenib and dabrafenib.
National Institutes of Health

Contact: Steve Graff
University of Pennsylvania School of Medicine

Public Release: 24-Feb-2014
Journal of Experimental Medicine
Two-pronged approach successfully targets DNA synthesis in leukemic cells
Researchers show that a novel two-pronged strategy targeting DNA synthesis can treat leukemia in mice while sparing damage to normal blood cells.
NIH/National Cancer Institute, National Institutes of Health

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 23-Feb-2014
Nature Chemical Biology
Researchers create synthetic version of heparin for use in kidney patients
Researchers at Rensselaer Polytechnic Institute and the University of North Carolina at Chapel Hill have created a synthetic form of low-molecular-weight heparin that can be reversed in cases of overdose and would be safer for patients with poor kidney function.
National Institutes of Health

Contact: Mary Martialay
Rensselaer Polytechnic Institute

Public Release: 23-Feb-2014
Nature Nanotechnology
Nanoparticles target anti-inflammatory drugs where needed
Researchers at the University of Illinois at Chicago have developed a system for precisely delivering anti-inflammatory drugs to immune cells gone out of control, while sparing their well-behaved counterparts. Their findings were published online Feb. 23 in Nature Nanotechnology.
National Institutes of Health, American Heart Association

Contact: Sharon Parmet
University of Illinois at Chicago

Public Release: 23-Feb-2014
Researchers pinpoint brain region essential for social memory
Researchers have determined that a small region of the hippocampus known as CA2 is essential for social memory, the ability of an animal to recognize another of the same species. A better grasp of the function of CA2 could prove useful in understanding and treating disorders characterized by altered social behaviors, such as autism, schizophrenia, and bipolar disorder. The findings, made in mice, were published today in the online edition of Nature.
NIH/National Institute of Mental Health, Howard Hughes Medical Institute

Contact: Joannie Danielides
Columbia University Medical Center

Public Release: 23-Feb-2014
A key protein is discovered as essential for malaria parasite transmission to mosquitos
Scientists studying the sexual transformation of the malaria parasite have solved a long-standing mystery in parasite biology. Two research teams have independently discovered that a single protein acts as the master genetic switch that triggers the development of male and female sexual forms of the malaria parasite. The discovery has important implications for human health.
National Institutes of Health, Damon Runyon Cancer Research Foundation, Wellcome Trust, European Comission, Biotechnology and Biological Sciences Research Council, Spanish Ministry of Science and Innovation, and others

Contact: Barbara K. Kennedy
Penn State

Public Release: 23-Feb-2014
Scientists transform skin cells into functioning liver cells
Scientists at the Gladstone Institutes and the University of California, San Francisco, have made an important breakthrough: they have discovered a way to transform skin cells into mature, fully functioning liver cells that flourish on their own, even after being transplanted into laboratory animals modified to mimic liver failure.
California Institute for Regenerative Medicine, National Institutes of Health, German Academic Exchange Service, Society of University Surgeons

Contact: Anne Holden
Gladstone Institutes

Public Release: 21-Feb-2014
New England Journal of Medicine
Promising cervical cancer study
Research on cervical cancer performed by a physician at the University of Arizona Cancer Center at St. Joseph's Hospital and Medical Center has been published in the New England Journal of Medicine. The multi-site research project by Bradley J. Monk, M.D., is expected to change the standard of care in advanced cervical cancer.
NIH/National Cancer Institute

Contact: Lynne Reaves
St. Joseph's Hospital and Medical Center

Public Release: 21-Feb-2014
Annals of Epidemiology
Reducing HIV transmission among drug injectors lowers AIDS mortality in heterosexuals
A recent study conducted by researchers from New York University's Center for Drug Use and HIV Research, led by Samuel R. Friedman, Director of both New York University's Center for Drug Use and HIV Research's interdisciplinary theoretical synthesis core, and the Institute for Infectious Disease Research at National Development and Research Institutes, sheds light on the pathways connecting HIV epidemics in different populations.
NIH/National Institute on Drug Abuse, Public Health Solutions, National Development and Research Institutes

Contact: Christopher James
New York University

Public Release: 21-Feb-2014
AIDS Education and Prevention
Researchers look to reduce hep C infections for injecting drug user
Researchers affiliated with New York University's Center for Drug Use and HIV Research are focusing on intervention strategies that highlight the lesser-known dangers of HCV transmission through the sharing of other injection equipment such as cookers, filters, drug-dilution water and water containers.
NIH/National Institute on Drug Abuse

Contact: Christopher James
New York University

Public Release: 21-Feb-2014
Journal of the National Cancer Institute
Selenium and vitamin E supplements can increase risk of prostate cancer in some men
A multi-center study led by Fred Hutchinson Cancer Research Center has found that high-dose supplementation with both the trace element selenium and vitamin E increase the risk of high-grade prostate cancer. But importantly, this risk depends upon a man's selenium status before taking the supplements.
NIH/National Cancer Institute, National Institutes of Health

Contact: Kristen Woodward
Fred Hutchinson Cancer Research Center

Public Release: 21-Feb-2014
Nature Communications
The parasite that escaped out of Africa
An international team has traced the origin of the second-worst malaria parasite of humans to Africa. The closest genetic relatives of human Plasmodium vivax were found only in Asian macaques, leading researchers to believe that P. vivax originated in Asia. This study overturns that, finding that wild-living apes in central Africa are widely infected with parasites that, genetically, are nearly identical to human P. vivax.
National Institutes of Health, Penn Center for AIDS Research, Agence Nationale de Recherche sur le Sida

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 20-Feb-2014
Biological Psychiatry
Study in mice raises question: Could PTSD involve immune response to stress?
Chronic stress that produces inflammation and anxiety in mice appears to prime their immune systems for a prolonged fight, causing the animals to have an excessive reaction to a single acute stressor weeks later, new research suggests.
NIH/National Institute of Mental Health, NIH/National Institute on Aging

Contact: Jonathan Godbout
Ohio State University

Public Release: 20-Feb-2014
NCI recommends the Wistar Institute receive $14.9 million support grant renewal
After an extensive review by a panel of top cancer experts, the National Cancer Institute rated The Wistar Institute Cancer Center as 'exceptional' and recommended renewal for Wistar's Support Grant with an award of $14.9 million over the next five years. The Grant funds the infrastructure and research support facilities that enable Wistar scientists to conduct their research.
NIH/National Cancer Institute

Contact: Greg Lester
The Wistar Institute

Public Release: 20-Feb-2014
Dismantling pancreas cancer's armor
Pancreas cancer is notoriously impervious to treatment and resists both chemotherapy and radiotherapy. It has also been thought to provide few targets for immune cells, allowing tumors to grow unchecked. But new research from Fred Hutchinson Cancer Research Center shows that pancreas cancer 'veils' itself from the immune system by recruiting specialized immune suppressor cells. The research team also found that removing these cells quickly triggers a spontaneous anti-tumor immune response.
NIH/National Cancer Institute, Giles W. and Elise G. Mead Foundation, Safeway Foundation, Jack and Sylvia Paul Fund, and others

Contact: Kristen Woodward
Fred Hutchinson Cancer Research Center

Public Release: 20-Feb-2014
Neurobiology of Aging
Study in fruitflies strengthens connection among protein misfolding, sleep loss, and age
Pathways of aging and sleep intersect at the circuitry of a cellular stress response pathway, and that by tinkering with those connections, it may be possible to alter sleep patterns in the aged for the better -- at least in fruit flies.
NIH/National Heart, Lung, and Blood Institute, NIH/National Institute on Aging

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 20-Feb-2014
Proceedings of the National Academy of Sciences
Surprising culprit found in cell recycling defect
Researchers at Washington University School of Medicine in St. Louis have identified an unusual cause of the lysosomal storage disorder called mucolipidosis III, at least in a subset of patients. Unlike most genetic diseases that involve dysfunctional or missing proteins, the culprit is a normal protein that ends up in the wrong place.
National Institutes of Health

Contact: Julia Evangelou Strait
Washington University School of Medicine

Public Release: 20-Feb-2014
Researchers look for culprit behind oral health problems in HIV-positive patients
Researchers want to help HIV-positive patients live better by understanding why their essentially dormant infection is still wreaking havoc in their mouths.
National Institutes of Health

Contact: Toni Baker
Medical College of Georgia at Georgia Regents University

Public Release: 20-Feb-2014
Journal of Clinical Oncology
Hypnosis therapy shown to decrease fatigue levels in breast cancer patients
Breast cancer patients receiving radiotherapy showed decreased fatigue as a result of cognitive behavioral therapy plus hypnosis, according to a study recently published in the Journal of Clinical Oncology.
NIH/National Cancer Institute, American Cancer Society

Contact: Mount Sinai Press Office
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 20-Feb-2014
Molecular Cell
Chemical chaperones have helped proteins do their jobs for billions of years
An ancient chemical, present for billions of years, appears to have helped proteins function properly since time immemorial.
National Institutes of Health, Howard Hughes Medical Institute

Contact: Laura Bailey
University of Michigan

Public Release: 20-Feb-2014
2014 Multidisciplinary Head and Neck Cancer Symposium
HPV-positive OPSCC patients nearly twice as likely to survive as HPV-negative patients
A retrospective analysis of oropharyngeal patients with recurrence of disease after primary therapy in the Radiation Therapy Oncology Group studies 0129 or 0522 found that HPV-positive patients had a higher overall survival rate than HPV-negative patients (at two years post-treatment, 54.6 percent versus 27.6 percent, respectively), according to research presented today at the 2014 Multidisciplinary Head and Neck Cancer Symposium.
NIH/National Cancer Institute, Bristol-Meyers Squibb

Contact: Michelle Kirkwood
American Society for Radiation Oncology

Showing releases 3051-3075 out of 3575.

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