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Key: Meeting M      Journal J      Funder F

Showing releases 3101-3125 out of 3686.

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Public Release: 30-Jan-2015
UTSW study links deficiency of cellular housekeeping gene with aggressive forms of breast cancer
UT Southwestern Medical Center scientists have identified a strong link between the most aggressive type of breast cancer and a gene that regulates the body's natural cellular recycling process, called autophagy.
National Institutes of Health, Cancer Prevention and Research Institute of Texas

Contact: Debbie Bolles
UT Southwestern Medical Center

Public Release: 30-Jan-2015
Moffitt study find loss of certain protein is associated with poor prognosis in breast, lung cancer
Moffitt Cancer Center researchers have found that breast and lung cancer patients who have low levels of a protein called tristetraprolin have more aggressive tumors and a poorer prognosis than those with high levels of the protein. Their study was published in the Dec. 26 issue of PLOS ONE.
NIH/National Cancer Institute

Contact: Kim Polacek
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 30-Jan-2015
Cell Death & Differentiation
LSU Health New Orleans makes discovery key to preventing blindness and stroke devastation
Research conducted at the LSU Health New Orleans Neuroscience Center of Excellence has discovered gene interactions that determine whether cells live or die in such conditions as age-related macular degeneration and ischemic stroke. These common molecular mechanisms in vision and brain integrity can prevent blindness and also promote recovery from a stroke.
NIH/National Eye Institute, NIH/National Institute of General Medical Sciences

Contact: Leslie Capo
Louisiana State University Health Sciences Center

Public Release: 30-Jan-2015
Nature Communications
New molecular target identified for treating cerebral malaria
A drug already approved for treating other diseases may be useful as a treatment for cerebral malaria, according to researchers at Harvard T. H. Chan School of Public Health. They discovered a novel link between food intake during the early stages of infection and the outcome of the disease, identifying two molecular pathways that could serve as new targets for treatment.
National Institutes of Health, Glenn Foundation for Medical Research, Harvard Chan School, Universidad Autonoma de Nuevo Leon

Contact: Marge Dwyer
Harvard T.H. Chan School of Public Health

Public Release: 29-Jan-2015
Altered dopamine signaling a clue to autism
Newly discovered genetic variations linked to autism spectrum disorder disrupt the function of the dopamine transporter, suggesting that altered dopamine signaling contributes to this common developmental condition, according to a Vanderbilt University-led research team.
National Institutes of Health

Contact: Bill Snyder
Vanderbilt University Medical Center

Public Release: 29-Jan-2015
Proceedings of the National Academy of Sciences
Picking up on the smell of evolution
UA researchers have discovered some of the changes in genes, physiology and behavior that enable a species to drastically change its lifestyle in the course of evolution.
National Science Foundation, John Templeton Foundation, National Institutes of Health, University of Arizona Foundation

Contact: Daniel Stolte
University of Arizona

Public Release: 29-Jan-2015
In a role reversal, RNAs proofread themselves
Building a protein is a lot like a game of telephone: information is passed along from one messenger to another, creating the potential for errors. Enzymatic machines proofread at each step, and scientists at CSHL have uncovered a new quality control mechanism along this path. But in a remarkable role reversal, the proofreading isn't done by an enzyme. Instead, one of the messengers itself has a built-in mechanism to prevent errors.
US National Institutes of Health, Howard Hughes Medical Institute, Jane Coffin Childs Memorial Fund for Medical Research, Robertson Research Fund of Cold Spring Harbor Laboratory Cold Spring Harbor Laboratory

Contact: Jaclyn Jansen
Cold Spring Harbor Laboratory

Public Release: 29-Jan-2015
Science Signaling
Erectile dysfunction drugs could protect liver from sepsis-induced damage, says Pitt team
Drugs that are on the market to treat erectile dysfunction could have another use: they might be able to protect the liver from damage caused by sepsis, a systemic inflammatory response to infection, say researchers at the University of Pittsburgh School of Medicine. They recently published their findings in Science Signaling.
National Institutes of Health

Contact: Anita Srikameswaran
University of Pittsburgh Schools of the Health Sciences

Public Release: 29-Jan-2015
Probiotic helps treat diabetes in rats, could lead to human remedy
Science may be one step closer to treating diabetes with a human probiotic pill, according to new Cornell University research. The researchers engineered a strain of lactobacillus, a human probiotic common in the gut, to secrete a Glucagon-like peptide 1. They then administered it orally to diabetic rats for 90 days and found the rats receiving the engineered probiotic had up to 30 percent lower high blood glucose, a hallmark of diabetes.
National Institutes of Health, Hartwell Foundation.

Contact: Melissa Osgood
Cornell University

Public Release: 29-Jan-2015
Molecular Metabolism
'Feeding and fasting' hormone adropin can improve insulin action
New research from a Saint Louis University scientist holds promise for type 2 diabetes treatment.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, American Diabetes Association, Proof of Principle Award from Novo Nordisk's Diabetes Innovation Award Program, Canadian Diabetes Association

Contact: Carrie Bebermeyer
Saint Louis University

Public Release: 29-Jan-2015
First-ever view of protein structure may lead to better anxiety drugs
When new medicines are invented, the drug may hit the intended target and nullify the symptoms, but nailing a bull's eye -- one that produces zero side effects -- can be quite elusive. New research conducted at Michigan State University and published in the current issue of Science has, for the first time, revealed the crystal structure of a key protein, TSPO, which is associated with several forms of anxiety disorders.
National Institutes of Health

Contact: Layne Cameron
Michigan State University

Public Release: 29-Jan-2015
Studies in Mycology
Researchers provide insights for reducing drug overdoses through community education
Results from a new study show that participants in drug overdose education programs tend to be parents (mostly mothers) who provide financial support for their son/daughter, have daily contact with their loved one, have applied for court-mandated treatment and have witnessed an overdose.
NIH/National Institute on Drug Abuse

Contact: Gina DiGravio
Boston University Medical Center

Public Release: 29-Jan-2015
$2.2 million grant enables IUPUI to study depression-cardiovascular disease link in HIV patients
Jesse Stewart of the School of Science and two colleagues have received a $2.2 million National Institutes of Health grant to investigate the links between depression, depression treatment and cardiovascular disease in adults with HIV. With the success of antiretroviral therapy, cardiovascular disease is now the leading cause of death in HIV-infected adults.
NIH/National Heart, Lung and Blood Institute

Contact: Cindy Fox Aisen
Indiana University-Purdue University Indianapolis School of Science

Public Release: 29-Jan-2015
Lancet HIV
HIV testing yields diagnoses in Kenya but few seek care
A sweeping effort in a rural region of Kenya to test all adults for HIV discovered 1,300 new infections, but few of the newly diagnosed people pursued treatment, a study in the journal Lancet HIV reports.
PEPFAR, National Institutes of Health, Bill & Melinda Gates Foundation

Contact: David Orenstein
Brown University

Public Release: 29-Jan-2015
Physicians explore why children with sickle cell disease are experiencing mixed results on hydroxyurea
Electronic medication monitoring caps may help physicians put together the puzzle of why children taking a medicine that promises to curb sickle cell disease are showing mixed, confusing results.
NIH/National Heart, Lung, and Blood Institute

Contact: Toni Baker
Medical College of Georgia at Georgia Regents University

Public Release: 29-Jan-2015
Archives of Sexual Behavior
Love and intimacy in later life -- new study reveals active sex lives of the over 70s
Older people are continuing to enjoy active sex lives well into their seventies and eighties, according to new research from The University of Manchester and NatCen Social Research.
NIH/National Institute on Aging, UK Government: Department for Communities and Local Government, Department of Health, Department for Transport, Department for Work and Pensions, and others

Contact: Deborah Linton
University of Manchester

Public Release: 29-Jan-2015
Circulation Research: Journal of the American Heart Association
Gut bacteria byproduct linked to chronic kidney disease for the first time
Cleveland Clinic researchers have, for the first time, linked trimethylamine N-oxide -- a gut metabolite formed during the digestion of egg-, red meat- or dairy-derived nutrients choline and carnitine -- to chronic kidney disease.
National Institutes of Health

Contact: Laura Ambro
Cleveland Clinic

Public Release: 29-Jan-2015
Dartmouth researchers determine key element in circadian clock speed
In a discovery that may lead to new treatments for sleep disorders, jet lag and other health problems tied to circadian rhythms, researchers at Dartmouth's Geisel School of Medicine have identified a determinant of the circadian clock's period.
NIH/National Institute of General Medical Sciences

Contact: Derik Hertel
The Geisel School of Medicine at Dartmouth

Public Release: 29-Jan-2015
New deep-brain imaging reveals separate functions for nearly identical neurons
Researchers at the UNC School of Medicine have used new deep-brain imaging techniques to link the activity of individual, genetically similar neurons to particular behaviors of mice. Specifically, for the first time ever scientists watched as one neuron was activated when a mouse searched for food while a nearly identical neuron next to it remained inactive; instead, the second neuron only became activated when the mouse began eating.
National Institutes of Health, Klarman Family Foundation, Foundation for Prader-Willi Research, department of psychiatry in the UNC School of Medicine

Contact: Mark Derewicz
University of North Carolina Health Care

Public Release: 29-Jan-2015
Among gut microbes, strains, not just species, matter
Sophisticated genomic techniques now allow scientists to estimate the strains, not just the species, in samples of the human gut's microbe collection. Differences in the strains of microorganisms present might account for the variable influence the gut's microbe community has on human health and disease. Understanding the effects of various strain combinations on such functions as metabolism, immunity and drug reactions might suggest ways to manipulate the gut microbiome to improve health.
National Institutes of Health

Contact: Leila Gray
University of Washington Health Sciences/UW Medicine

Public Release: 29-Jan-2015
Why is a dolphin not a cat?
A study of gene regulation in 20 mammals, published in Cell, provides new insights into how species diverged millions of years ago. The findings demonstrate how methods and tools for genetic analysis of humans and mice can be adapted to study non-model species, such as whales and Tasmanian devils.
Cancer Research UK, European Molecular Biology Laboratory, Wellcome Trust, European Research Council, EMBO Young Investigator Programme, National Science Foundation, National Institutes of Health

Contact: Mary Todd Bergman
European Molecular Biology Laboratory

Public Release: 29-Jan-2015
New clues about a brain protein with high affinity for Valium
Valium, one of the best known antianxiety drugs, produces its calming effects by binding with a particular protein in the brain. But the drug has an almost equally strong affinity for a completely different protein. New studies revealing atomic level details of this secondary interaction might offer clues about Valium's side effects and point the way to more effective drugs.
National Institutes of Health, New York Structural Biology Center, DOE/Office of Science

Contact: Karen McNulty Walsh
DOE/Brookhaven National Laboratory

Public Release: 28-Jan-2015
Geophysical Research Letters
Satellites can improve regional air quality forecasting
University of Iowa researchers found that data gathered from geo-stationary satellites -- satellites orbiting Earth at about 22,000 miles above the equator and commonly used for telecommunications and weather imaging -- can greatly improve air-quality forecasting.
NASA, US Environmental Protection Agency, National Science Foundation, National Institutes of Health, Korea Environmental Industry & Technology Institute

Contact: Gary Galluzzo
University of Iowa

Public Release: 28-Jan-2015
Journal of Interpersonal Violence
Child maltreatment not a clear path to adult crime
Research has long made a connection between childhood abuse and neglect and crime in adulthood. But a University of Washington study found that when other factors are considered, that link all but disappears.
NIH/National Institute of Child Health and Human Development, National Institute of Justice

Contact: Deborah Bach
University of Washington

Public Release: 28-Jan-2015
Annals of the American Thoracic Society
Moderate lifetime marijuana smoking linked to airway irritation but not lung function
A research study based on analysis of publicly available data has found that recent marijuana use was associated with symptoms of airway inflammation, but that moderate lifetime use was not associated with clinically significant changes in measures of lung function. The study is the largest cross-sectional analysis of the relationship between marijuana use and measures of lung health to date.
National Institutes of Health

Contact: Holly Korschun
Emory Health Sciences

Showing releases 3101-3125 out of 3686.

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