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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3126-3150 out of 3555.

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Public Release: 11-Feb-2014
New target isolated for leukemia drug development
The protein WTAP and its relationship to Heat shock protein 90 are two discoveries at The University of Texas Health Science Center at San Antonio that open the door to developing more effective therapies in Acute Myeloid Leukemia.
Castella Endowment for Aging Research; NIH/National Cancer Institute, National Institutes of Health, Hyundai Hope on Wheels

Contact: Elizabeth Allen
University of Texas Health Science Center at San Antonio

Public Release: 11-Feb-2014
FASEB Journal
Nanoparticles treat muscular dystrophy in mice
Researchers at Washington University School of Medicine in St. Louis have demonstrated a new approach to treating muscular dystrophy. Mice with a form of this muscle-weakening disease showed improved strength and heart function when treated with nanoparticles loaded with rapamycin, an immunosuppressive drug recently found to improve recycling of cellular waste.
National Institutes of Health, Muscular Dystrophy Association, American Heart Association

Contact: Julia Evangelou Strait
Washington University School of Medicine

Public Release: 11-Feb-2014
Journal of Adolescent Health
Data on today's youth reveal childhood clues for later risk of STDs
Here's yet another reason to focus on kids' early years. Children who grow up in well-managed households, enjoy school, and have friends who stay out of trouble report fewer sexually transmitted diseases in young adulthood, according to a new analysis.
NIH/National Institute on Drug Abuse, Robert Wood Johnson Foundation

Contact: Molly McElroy
University of Washington

Public Release: 11-Feb-2014
Biology of Blood and Marrow Transplantation
Study: Resilience in parents of children undergoing stem cell transplant
After a child's stem cell transplant, parents feel increased distress at the time of the procedure, but eventually recover to normal levels of adjustment.
National Institutes of Health

Contact: Garth Sundem
University of Colorado Denver

Public Release: 11-Feb-2014
Behavior Therapy
RI Hospital: Cognitive behavioral therapy benefits patients with body dysmorphic disorder
In a recent study, researchers at Rhode Island Hospital found significant benefits of cognitive behavioral therapy as a treatment modality for patients with Body Dysmorphic Disorder (BDD). BDD is a common, often severe, and under-recognized body image disorder that affects an estimated 1.7 percent to 2.4 percent of the population. This study demonstrated significant improvement in patients' BDD symptoms and level of disability, as well as high levels of patient satisfaction with the treatment.
NIH/National Institute of Mental Health

Contact: Ellen Slingsby

Public Release: 11-Feb-2014
PLOS Pathogens
Could statins be used to fight a deadly viral infection?
Two Perelman School of Medicine microbiologists may have found a way to use statins, the well-known blockbuster cholesterol-lowering drugs, to fight the hantavirus, a mysterious and lethal microorganism that appeared suddenly in the US southwest over 20 years ago.
National Institutes of Health

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 11-Feb-2014
A breast cancer drug to fight fungal disease?
The drug tamoxifen appears to kill a fungus associated with a deadly brain infection that afflicts HIV/AIDS patients, according to a University of Rochester study published online today by mBio, the journal of the American Society for Microbiology.
NIH/National Institute of Allergy and Infectious Disease

Contact: Leslie Orr
University of Rochester Medical Center

Public Release: 11-Feb-2014
Psychological Science
After committing a crime, guilt and shame predict re-offense
Within three years of being released from jail, two out of every three inmates in the US wind up behind bars again -- a problem that contributes to the highest incarceration rate of any country in the world. New research suggests that the degree to which inmates' express guilt or shame may provide an indicator of how likely they are to re-offend.
NIH/National Institute on Drug Abuse

Contact: Anna Mikulak
Association for Psychological Science

Public Release: 11-Feb-2014
Brilliant blue G may shine in treating traumatic brain injuries
A close cousin of the dye that makes fabric, M&M's and sports drinks blue may improve recovery from traumatic brain injuries.
National Institutes of Health

Contact: Toni Baker
Medical College of Georgia at Georgia Regents University

Public Release: 11-Feb-2014
Psychological Medicine
Smoking cessation may improve mental health
Although many health professionals who treat people with psychiatric problems overlook their patients' smoking habits, new research at Washington University School of Medicine in St. Louis shows that people who struggle with mood problems or addiction can safely quit smoking and that kicking the habit is associated with improved mental health.
NIH/National Center for Research Resources, NIH/National Institute on Drug Abuse, American Cancer Society

Contact: Jim Dryden
Washington University School of Medicine

Public Release: 11-Feb-2014
Journal of Neuroscience
Exercise may slow retinal degeneration
Moderate aerobic exercise helps to preserve retinal function in a model of age-related macular degeneration.
NIH/National Eye Institute, US Department of Veterans Affairs, Abraham J. and Phyllis Katz Foundation

Contact: Quinn Eastman
Emory Health Sciences

Public Release: 11-Feb-2014
The Journal of Neuroscience
Exercise may slow progression of retinal degeneration
Moderate aerobic exercise helps to preserve the structure and function of nerve cells in the retina after damage, according a Feb. 12 in The Journal of Neuroscience. The findings suggest exercise may be able to slow the progression of retinal degenerative diseases. Age-related macular degeneration, one of the leading causes of blindness in the elderly, is caused by the death of light-sensing nerve cells in the retina called photoreceptors.
NIH/National Eye Institute, US Department of Veterans Administration Affairs, Katz Foundation

Contact: Anne Nicholas
Society for Neuroscience

Public Release: 11-Feb-2014
Kidney failure risk for organ donors 'extremely low'
The risk of a kidney donor developing kidney failure in the remaining organ is much lower than in the population at large, even when compared with people who have two kidneys, according to results of new Johns Hopkins research.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Stephanie Desmon
Johns Hopkins Medicine

Public Release: 11-Feb-2014
Frontiers in Human Neuroscience
How our brain networks: Research reveals white matter 'scaffold' of human brain
For the first time, neuroscientists have systematically mapped the white matter "scaffold" of the human brain, the critical communications network that supports brain function.
National Institutes of Health

Contact: Suzanne Wu
University of Southern California

Public Release: 10-Feb-2014
Proceedings of the National Academy of Sciences
Better RNA interference, inspired by nature
New MIT nanoparticles offer best-ever gene silencing, could help treat liver diseases.
Alnylam Pharmaceuticals, National Institutes of Health

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 10-Feb-2014
TGen study uncovers possible genetic markers in breast cancer that spreads to the brain
The Translational Genomics Research Institute has uncovered possible genetic origins of breast cancer that spreads to the brain, according to a first-of-its-kind study published in the scientific journal PLOS ONE.
National Institutes of Health, Flinn Foundation, C.A.R.E.

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 10-Feb-2014
Journal of Biological Chemistry
Recycling of 'chauffeur protein' helps regulate fat production
Studying a cycle of protein interactions needed to make fat, Johns Hopkins researchers say they have discovered a biological switch that regulates a protein that causes fatty liver disease in mice. Their findings, they report, may help develop drugs to decrease excessive fat production and its associated conditions in people, including fatty liver disease and diabetes.
Pancreatic Cancer Action Network, NIH/National Heart, Lung and Blood Institute

Contact: Catherine Kolf
Johns Hopkins Medicine

Public Release: 10-Feb-2014
Nature Communications
Chips that listen to bacteria
Researchers led by Ken Shepard (electrical engineering and biomedical engineering professor, Columbia Engineering) and Lars Dietrich, biological sciences assistant professor, Columbia University) have shown integrated circuit technology can be used for a most unusual application -- the study of signaling in bacterial colonies. They have developed a chip based on CMOS technology that enables them to electrochemically image the signaling molecules from these colonies spatially and temporally -- they've developed chips that "listen" to bacteria.
National Institutes of Health, National Science Foundation

Contact: Holly Evarts
Columbia University School of Engineering and Applied Science

Public Release: 10-Feb-2014
American Journal of Respiratory and Critical Care Medicine
Researchers discover immune signature that predicts poor outcome in influenza patients
St. Jude Children's Research Hospital scientists have identified a signature immune response that might help doctors identify which newly diagnosed influenza patients are most likely to develop severe symptoms and suffer poor outcomes. The findings also help explain why infants and toddlers are at elevated risk for flu complications. The research appears in the upcoming issue of the American Journal of Respiratory and Critical Care Medicine.
NIH/National Institute of Allergy and Infectious Diseases, ALSAC

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 10-Feb-2014
Cancer Cell
Normal enzyme aids a mutant 1 to fuel blood cancer's growth
Researchers from Dana-Farber/Boston Children's Cancer and Blood Disorders Center report that a normal enzyme called SYK pairs with FLT3, the most commonly mutated enzyme found in acute myelogenous leukemia (AML), to promote the cancer's growth. This partnership also promotes AML cells' resistance to treatment with FLT3-blocking drugs and could explain the relatively poor showing of FLT3 inhibitors in clinical studies.
NIH/National Cancer Institute, American Cancer Society

Contact: Irene Sege
Dana-Farber Cancer Institute

Public Release: 10-Feb-2014
Proceedings of the National Academy of Sciences
Heart attack research discovers new treatment target
Research led by David Lefer, Ph.D., Professor and Director of the Cardiovascular Center of Excellence at LSU Health Sciences Center New Orleans School of Medicine, demonstrates for the first time cross-talk between two protective signaling molecules during a heart attack. By providing new and important information about the mechanisms involved in heart attacks and organ transplantation, the research identifies a potential new treatment target for heart disease.
NIH/National Heart, Lung, and Blood Institute, Canadian Institutes of Health Research, and others

Contact: Leslie Capo
Louisiana State University Health Sciences Center

Public Release: 10-Feb-2014
Angewandte Chemie International Edition
Nanomotors are controlled, for the first time, inside living cells
Nanomotors have been controlled inside living cells for the first time, report a team of chemists and engineers at Penn State University. The scientists placed tiny rocket-shaped synthetic motors inside live human cells, propelled them with ultrasonic waves and steered them magnetically to spin and to battering against the cell membrane.
National Science Foundaiton, National Institutes of Health, Penn State University

Contact: Barbara K. Kennedy
Penn State

Public Release: 10-Feb-2014
Proceedings of the National Academy of Sciences
New live-cell printing technology works like ancient Chinese woodblocking
With a nod to 3rd century Chinese woodblock printing and children's rubber stamp toys, researchers in Houston have developed a way to print living cells onto any surface, in virtually any shape. Unlike recent, similar work using inkjet printing approaches, almost all cells survive the process, scientists report in this week's Proceedings of the National Academy of Sciences.
National Institutes of Health, US Department of Defense, Alliance for Nanohealth

Contact: David Bricker
Houston Methodist

Public Release: 9-Feb-2014
Nature Methods
Optogenetic toolkit goes multicolor
MIT researchers have found new light-sensitive proteins that allow scientists to study how multiple sets of neurons interact with each other.
National Institutes of Health, Massachusetts Institute of Technology Media Lab, National Science Foundation, Wallace H. Coulter Foundation, Alfred P. Sloan Foundation, NARSAD Young Investigator Grant, Human Frontiers Science Program, and others

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 9-Feb-2014
Nature Chemical Biology
Scientists invent advanced approach to identify new drug candidates from genome sequence
In research that could ultimately lead to many new medicines, scientists from the Florida campus of The Scripps Research Institute have developed a potentially general approach to design drugs from genome sequence. As a proof of principle, they identified a highly potent compound that causes cancer cells to attack themselves and die.
National Institutes of Health, Camille and Henry Dreyfus Foundation

Contact: Eric Sauter
Scripps Research Institute

Showing releases 3126-3150 out of 3555.

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