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Showing releases 3126-3150 out of 3164. << < 121 | 122 | 123 | 124 | 125 | 126 | 127 > >>
Public Release: 8-Dec-2011
Study probes genetic link to sickle cell pain management
A study that may help personalize pain medication management for sickle cell disease patients is underway at Georgia Health Sciences University.
National Institutes of Health
Contact: Sharron Walls
swalls@georgiahealth.edu
706-721-8605
Georgia Health Sciences University
Public Release: 8-Dec-2011
Physics in Medicine and Biology
New Columbia engineering technique diagnoses non-periodic arrhythmias in a single heartbeat
Thanks to a new Columbia Engineering School study, doctors may now be able to diagnose in their offices non-periodic arrhythmias within a single heartbeat. The researchers sent unfocused ultrasound waves through the closed chest into the heart and captured fast-frame-rate images that enabled them for the first time to map transient events such as the electromechanical activation that occurs over a few tens of milliseconds while also imaging the entire heart within a single beat.
NIH/National Institute of Biomedical Imaging and Bioengineering
Contact: Holly Evarts
holly@engineering.columbia.edu
212-854-3206
Columbia University
Public Release: 8-Dec-2011
Cancer
PSA testing, combined with other relevant patient data can reduce unnecessary prostate biopsies
Prostate cancer screening that combines an adjusted blood test with other factors including the size of the gland, the patient's overall weight and family history, can help up to one-quarter of men avoid biopsies and the risks associated with them, a Beth Israel Deaconess Medical Center-led research team says.
NIH/National Cancer Institute
Contact: Jerry Berger
jberger@bidmc.harvard.edu
617-667-7308
Beth Israel Deaconess Medical Center
Public Release: 8-Dec-2011
Science
The heart of the plant
Food prices are soaring at the same time as the Earth's population is nearing 9 billion. As a result the need for increased crop yields is extremely important. New research led by Carnegie's Wolf Frommer into the system by which sugars are moved throughout a plant -- from the leaves to the harvested portions and elsewhere -- could be crucial for addressing this problem. Their work is published Dec. 8 by Science Express.
US Department of Energy, National Institutes of Health, Carnegie Institution for Science, Scholarship Program of Chinese Scholarship Council, Max-Planck-Gesellschaft
Contact: Wolf Frommer
wfrommer@CarnegieScience.edu
650-739-4208
Carnegie Institution
Public Release: 8-Dec-2011
PLOS Pathogens
Changing the locks: HIV discovery could allow scientists to block virus's entry into cell nucleus
Scientists have found the 'key' that HIV uses to enter our cells' nuclei, allowing it to disable the immune system and cause AIDS. The finding, published today in the open access journal PLoS Pathogens, provides a potential new target for anti-AIDS drugs that could be more effective against drug-resistant strains of the virus.
Wellcome Trust, National Institute of Health Research, Medical Research Council, National Institutes of Health, University of Pennsylvania Center for AIDS Research, Pennsylvania Department of Health
Contact: Craig Brierley
c.brierley@wellcome.ac.uk
44-207-611-7329
Wellcome Trust
Public Release: 8-Dec-2011
Science
New target found for aggressive cancer gene
Researchers have found a way to kill human cells hijacked by a potent cancer oncogene known as Myc.
National Institutes of Health, Susan G. Komen for the Cure, U.S. Army Innovator Award
Contact: David Cameron
david_cameron@hms.harvard.edu
617-432-0441
Harvard Medical School
Public Release: 8-Dec-2011
Science
Helping your fellow rat: Rodents show empathy-driven behavior
The first evidence of empathy-driven helping behavior in rodents has been observed in laboratory rats that repeatedly free companions from a restraint, according to a new study by University of Chicago neuroscientists. The observation, published today in Science, places the origin of pro-social helping behavior earlier in the evolutionary tree than previously thought.
NIH/National Institute on Drug Abuse, National Science Foundation
Contact: Robert Mitchum
robert.mitchum@uchospitals.edu
773-795-5227
University of Chicago Medical Center
Public Release: 8-Dec-2011
Journal of Studies on Alcohol and Drugs
Freshman women's binge drinking tied to sexual assault risk
Many young women who steer clear of alcohol while they're in high school may change their ways once they go off to college. And those who take up binge drinking may be at relatively high risk of sexual assault, according to a study in the January issue of the Journal of Studies on Alcohol and Drugs.
NIH/National Institute on Alcohol Abuse and Alcoholism
Contact: John DellaContrada
dellacon@buffalo.edu
716-645-4601
Journal of Studies on Alcohol and Drugs
Public Release: 8-Dec-2011
2011 CTRC-AACR San Antonio Breast Cancer Symposium
Potential breast cancer prevention agent found to lower levels of 'good' cholesterol over time
Exemestane steadily lowered levels of "good" cholesterol in women taking the agent as part of a breast cancer prevention study, say researchers at Georgetown Lombardi Comprehensive Cancer Center. Exemestane, an aromatase inhibitor used to treat estrogen receptor-positive breast cancer, is being tested to prevent breast cancer in women at an increased risk of developing the disease.
Georgetown University, NIH/National Cancer Institute, National Institutes of Health, Pfizer Inc.
Contact: Karen Mallet
km463@georgetown.edu
Georgetown University Medical Center
Public Release: 7-Dec-2011
Development
Researchers discover that changes in bioelectric signals cause tadpoles to grow eyes in back, tail
For the first time, scientists have altered natural bioelectrical communication among cells to directly specify the type of new organ to be created at a particular location within a vertebrate organism. Using genetic manipulation of membrane voltage in Xenopus (frog) embryos, biologists at Tufts University's School of Arts and Sciences were able to cause tadpoles to grow eyes outside of the head area.
National Institutes of Health
Contact: Alex Reid
alexander.reid@tufts.edu
617-627-4173
Tufts University
Public Release: 7-Dec-2011
Journal of Obesity
Stress reduction and mindful eating curb weight gain among overweight women
In a study by UCSF researchers published online in the Journal of Obesity, mastering simple mindful eating and stress-reduction techniques helped prevent weight gain even without dieting.
Mount Zion Health Fund, William Bowes, Jr., Fund, Robert Deidrick Fund, Robert Wood Johnson Foundation, National Institutes of Health
Contact: Jeffrey Norris
jeff.norris@ucsf.edu
415-502-6397
University of California - San Francisco
Public Release: 7-Dec-2011
Science Translational Medicine
When prophecy fails: How to better predict success in HIV prevention clinical trials
New research from the University of North Carolina at Chapel Hill schools of medicine and pharmacy may help explain the failure of some recent clinical trials of prevention of HIV infection, compared to the success of others that used the same drugs.
National Institutes of Health, UNC Center for AIDS Research, UNC TraCS Clinical Translational Research Center, Gilead Sciences Investigator Initiated Research Program
Contact: Lisa Chensvold
lisa_chensvold@med.unc.edu
919-843-5719
University of North Carolina Health Care
Public Release: 7-Dec-2011
Better CMT outcome measurement is Wayne State University physician's goal
A Wayne State University physician is seeking a better way to determine the effectiveness of treatments for Charcot-Marie-Tooth disease, or inherited sensory-motor neuropathy, a disease that afflicts one in 2,500 people.
National Institutes of Health
Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Public Release: 7-Dec-2011
Cerebral Cortex
Max Planck Florida Institute scientists create first realistic 3D reconstruction of a brain circuit
Researchers from the lab of Nobel laureate Bert Sakmann, MD, Ph.D. at the Max Planck Florida Institute report that, using a conceptually new approach and state-of-the-art research tools, they have created the first realistic three-dimensional diagram of a thalamocortical column in the rodent brain. This is the first step toward creating a complete computer model of the brain, and may ultimately lead to an understanding of how the brain computes and how it goes awry in disease.
Max Planck Society, VU University Amsterdam/Center for Neurogenomics and Cognitive Research, NIH/National Institute of Neurological Disorders and Stroke, Klingenstein Fund, Rita Allen Foundation, NIH/National Institute of General Medical Sciences
Contact: Dennis Tartaglia
dtartaglia@tartagliacommunications.com
732-545-1848
Tartaglia Communications
Public Release: 7-Dec-2011
Journal of Experimental Medicine
Traumatic injury sets off a 'genomic storm' in immune system pathways
Serious traumatic injuries, including major burns, set off a "genomic storm" in human immune cells, altering around 80 percent of the cells' normal gene expression patterns.
NIH/National Institute of General Medical Sciences
Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital
Public Release: 7-Dec-2011
Neuron
Research could help people with declining sense of smell
Cells in the nose – smell sensors, primarily – are constantly replaced as old ones die off. Olfactory stem cells are the source for these new cells, but how do they determine when to form mature cells? UC Berkeley neuroscientist John Ngai and colleague Russell Fletcher have found a genetic trigger – a transcription factor – that acts as a brake on differentiation. Removing it makes stem cells change into mature olfactory cells at the expense of self-renewal.
NIH/National Institute on Deafness and Other Communication Disorders, California Institute for Regenerative Medicine
Contact: Robert Sanders
rsanders@berkeley.edu
510-643-6998
University of California - Berkeley
Public Release: 7-Dec-2011
Science Translational Medicine
Study could lead to drug therapies for preventing atherosclerosis
By changing the behavior of certain cells within human blood vessels, Cornell University researchers have discovered important clues as to the underlying causes of atherosclerosis – a discovery researchers hope can lead to more targeted drug therapies for the prevention of the disease.
American Heart Association, American Federation for Aging Research, National Institutes of Health, L’Oreal USA Fellowship for Women in Science
Contact: Syl Kacapyr
vpk6@cornell.edu
607-255-7701
Cornell University
Public Release: 7-Dec-2011
New England Journal of Medicine
Mayo Clinic collaboration finds multiple sclerosis often starts in brain's outer layers
Multiple sclerosis may progress from the outermost layers of the brain to its deep parts, and isn't always an "inside-out" process as previously thought, reported a new collaborative study from researchers at the Mayo Clinic and the Cleveland Clinic. The traditional understanding is that the disease begins in the white matter that forms the bulk of the brain's inside, and extends to involve the brain's superficial layers, the cortex. Study findings support an opposite, outside-in process.
National MS Society, National Institutes of Health
Contact: Brian Kilen
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Public Release: 7-Dec-2011
Public Library of Science
Evolution reveals missing link between DNA and protein shape
Using evolutionary genetic information, an international team of researchers has taken major steps toward solving a classic problem of molecular biology: Predicting how a protein will fold in three dimensions.
NIH/National Cancer Institute, Engineering and Physical Sciences Research Council of the United Kingdom
Contact: David Cameron
david_cameron@hms.harvard.edu
617-432-0441
Harvard Medical School
Public Release: 7-Dec-2011
Human Reproduction
Stress in early pregnancy can lead to shorter pregnancies, more pre-term births and fewer baby boys
Stress in the second and third months of pregnancy can shorten pregnancies, increase the risk of pre-term births and may affect the ratio of boys to girls being born, leading to a decline in male babies. These are the conclusions of a study, published in Human Reproduction journal, that investigated the effect on pregnant women of the stress caused by the 2005 Tarapaca earthquake in Chile.
National Science Foundation, National Institutes of Health
Contact: Emma Mason (media enquiries only)
wordmason@mac.com
European Society of Human Reproduction and Embryology
Public Release: 7-Dec-2011
2011 CTRC-AACR San Antonio Breast Cancer Symposium
Anti-estrogen combo better than single drug for hormone-sensitive breast cancer
A phase III study by the SWOG clinical trials network shows new treatment combining anastrozole and fulvestrant can lengthen lives of post-menopausal women with hormone receptor-positive metastatic breast cancer.
NIH/National Cancer Institute, AstraZeneca Pharmaceuticals
Contact: Frank DeSanto
fdesanto@umich.edu
734-998-0114
University of Michigan Health System
Public Release: 7-Dec-2011
2011 CTRC-AACR San Antonio Breast Cancer Symposium
Changing order drugs are taken boosts breast cancer survival
Changing the order in which two drugs are taken significantly extended the lives of women with metastatic breast cancer, researchers reported at the San Antonio Breast Cancer Symposium.
NIH/National Cancer Institute
Contact: Jim Ritter
jritter@lumc.edu
708-216-2445
Loyola University Health System
Public Release: 7-Dec-2011
Genes & Development
Long non-coding RNA prevents the death of maturing red blood cells
A long non-coding RNA prevents programmed cell death during one of the final stages of red blood cell differentiation, according to Whitehead Institute researchers. Preventing normal cell death is a key step in the development of leukemias and other cancers. Because of its role in red blood cell apoptosis, this lncRNA or the pathways through which it exerts its anti-apoptotic effects may represent potential therapeutic targets.
Life Sciences Research Foundation, National Institutes of Health
Contact: Nicole Giese
giese@wi.mit.edu
617-258-6851
Whitehead Institute for Biomedical Research
Public Release: 6-Dec-2011
Molecular Biology and Evolution
Penn geneticists help show bitter taste perception is not just about flavors
Long the bane of picky eaters everywhere, broccoli's taste is not just a matter of having a cultured palate; Some people can easily taste a bitter compound in the vegetable that others have difficulty detecting. Now a team of Penn researchers has helped uncover the evolutionary history of one of the genes responsible for this trait. Beyond showing the ancient origins of the gene, the researchers discovered something unexpected: Something other than taste must have driven its evolution.
National Science Foundation, National Institutes of Health, David and Lucile Packard Career Award
Contact: Evan Lerner
elerner@upenn.edu
215-573-6604
University of Pennsylvania
Public Release: 6-Dec-2011
Nature
Addressing pain and disease on the fly
Studies of a protein that fruit flies use to sense heat and chemicals may someday provide solutions to human pain and the control of disease-spreading mosquitoes.
In the current issue of Nature, biologist Paul Garrity of the National Center for Behavioral Genomics at Brandeis University and his team discover how fruit flies distinguish the warmth of a summer day from the pungency of wasabi by using TRPA1, a protein whose human relative is critical for pain and inflammation.
National Science Foundation, NIH/National Institute of Mental Health, NIH/National Institute of Neurological Disorders and Stroke
Contact: Susan Chaityn Lebovits
lebovits@brandies.edu
781-736-4027
Brandeis University
Showing releases 3126-3150 out of 3164. << < 121 | 122 | 123 | 124 | 125 | 126 | 127 > >>
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