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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 3126-3150 out of 3465.

<< < 121 | 122 | 123 | 124 | 125 | 126 | 127 | 128 | 129 | 130 > >>

Public Release: 25-Oct-2013
Journal of Clinical Investigation
Itch maintains regulatory T cell stability
In this issue of the Journal of Clinical Investigation, Yun-Cai Liu and colleagues at the La Jolla Institute for Allergy and Immunology identified the E3 ubiquitin ligase Itch as a regulator of Tregs stability.
National Research Foundation of Korea, NIH/National Institute of Allergy and Infectious Diseases

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 25-Oct-2013
Journal of Clinical Investigation
Reduction of reactive oxygen species in diabetes-associated nephrology
In this issue of the Journal of Clinical Investigation, Kumar Sharma and colleagues at the University of California, San Diego determined that ROS production was actually reduced in kidneys of diabetic mice, and this decrease was associated with lowered activity of the major energy-sensing enzyme, AMPK.
National Institutes of Health, Christini Fund, Wright Foundation, Lennox Foundation

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 25-Oct-2013
Journal of Clinical Investigation
Researchers track lethal prostate cancer to determine clonal origin
In this issue of the Journal of Clinical Investigation, Srinivasan Yegnasubramanian and colleagues at Johns Hopkins University track the development of lethal prostate cancer in a patient.
National Institutes of Health, NIH/National Cancer Institute, Prostate Cancer Foundation David Mazzone Challenge Award and Creativity Award, The V Found

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 25-Oct-2013
Journal of Clinical Investigation
Ionizing radiation exposure promotes fusion oncogene formation
In this issue of the Journal of Clinical Investigation, James Fagin and colleagues at Memorial Sloan-Kettering Cancer Institute, examined tissues from Ukrainian PTC patients that were children at the time of the Chernobly catastrophe and identified their cancer-driving mutations.
National Institutes of Health, Margot Rosenberg Pulitzer Foundation, Byrne Fund, Lefkofsky Family Foundation

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 25-Oct-2013
Journal of Clinical Investigation
JCI early table of contents for Oct. 25, 2013
This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, Oct. 25, 2013 in the JCI: Ionizing radiation exposure promotes fusion oncogene formation, Researchers track lethal prostate cancer to determine clonal origin, Reduction of reactive oxygen species in diabetes-associated nephrology, Synthetic vitamin D receptor ligands reduce murine kidney fibrosis, Itch maintains regulatory T cell stability, Essential amino acid supplementation in patients following total knee arthroplasty
National Institutes of Health, United Therapeutics Inc., Ministerio de Educación y Ciencia, Fundación Ramón Areces, The Cardiova

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation

Public Release: 24-Oct-2013
Stroke
Experimental drug reduces brain damage, eliminates brain hemorrhaging in rodents afflicted by stroke
Developed by a team led by USC physician-scientist Berislav V. Zlokovic, the experimental drug 3K3A-APC shows promise as a stand-alone therapy for stroke or in combination with the FDA-approved clot-busting drug therapy tPA (tissue plasminogen activator).
National Institutes of Health

Contact: Alison Trinidad
alison.trinidad@usc.edu
323-442-3941
University of Southern California - Health Sciences

Public Release: 24-Oct-2013
Stroke
Ultrasound device combined with clot-buster safe for stroke, say UTHealth researchers
A study led by researchers at the University of Texas Health Science Center at Houston showed that a hands-free ultrasound device combined with a clot-busting drug was safe for ischemic stroke patients.
National Institutes of Health

Contact: Deborah Lake
deborah.m.lake@uth.tmc.edu
713-500-3304
University of Texas Health Science Center at Houston

Public Release: 24-Oct-2013
International Journal of Behavioral Development
Behavior problems in preschool and child care centers may be an issue of genes
A new study suggests that some children may be genetically predisposed to developing behavioral problems in child care and preschool settings. Previous research has found that some children develop behavior problems at child care centers and preschools, despite the benefit of academic gains. It was never known, however, why some youngsters struggle in these settings and others flourish. The new study indicates that some children may be acting out due to poor self-control and temperament problems that they inherited from their parents.
National Institutes of Health

Contact: Shannon Lipscomb
shannon.lipscomb@osucascades.edu
541-322-3137
Oregon State University

Public Release: 24-Oct-2013
Journal of General Physiology
Identifying a mystery channel crucial for hearing
Our ability to hear relies on hair cells, sensory receptors that mechanically amplify low-level sound that enters the inner ear through a transduction channel. Although the transduction channel was characterized more than 30 years ago, researchers have been unable to identify its molecular components. A new study could help lead to a definitive identification of this mystery channel.
NIH/National Institutes on Deafness and other Communication Disorders

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press

Public Release: 24-Oct-2013
Science
What is it about your face?
Berkeley Lab researchers found thousands of gene enhancers -- regulatory sequences of DNA that act to turn-on or amplify the expression of a specific gene -- are involved in the development of the human face. These enhancers help explain why every human face is as unique as a fingerprint.
US Department of Energy, National Institutes of Health

Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory

Public Release: 24-Oct-2013
PLOS Genetics
Genetic analysis reveals insights into the genetic architecture of OCD, Tourette syndrome
An international research consortium led by investigators at Massachusetts General Hospital and the University of Chicago has answered several questions about the genetic background of obsessive-compulsive disorder and Tourette syndrome, providing the first direct confirmation that both are highly heritable and also revealing major differences between the underlying genetic makeup of the disorders.
National Institutes of Health, Tourette Syndrome Association, David Judah Fund

Contact: Mike Morrison
mdmorrison@partners.org
617-724-6425
Massachusetts General Hospital

Public Release: 24-Oct-2013
Cell Reports
Researchers apply brainpower to understanding neural stem cell differentiation
How do humans and other mammals get so brainy? In a paper that will be published in Cell Reports on October 24, USC researcher Wange Lu, Ph.D., and his colleagues explained how neural stem and progenitor cells differentiate into neurons and related cells called glia. Neural stem and progenitor cells offer tremendous promise as a future treatment for neurodegenerative disorders, and understanding their differentiation is the first step towards harnessing this therapeutic potential.
National Institutes of Health

Contact: Cristy Lytal
lytal@med.usc.edu
University of Southern California - Health Sciences

Public Release: 24-Oct-2013
Science
Yeast, human stem cells drive discovery of new Parkinson's disease drug targets
Using a discovery platform whose components range from yeast cells to human stem cells, Whitehead Institute scientists have identified a novel Parkinson's disease drug target and a compound capable of repairing neurons derived from Parkinson's patients.
National Institutes of Health, Howard Hughes Medical Institute, JPB Foundation, Eleanor Schwartz Charitable Foundation, Bachmann Strauss Dystonia & Parkinson Foundation

Contact: Matt Fearer
fearer@wi.mit.edu
617-452-4630
Whitehead Institute for Biomedical Research

Public Release: 24-Oct-2013
American Society of Human Genetics Annual Meeting
Researchers identify gene variant that raises risk for colorectal cancer from eating processed meat
A common genetic variant that affects one in three people significantly increases the risk of colorectal cancer from the consumption of red meat and processed meat.
National Institutes of Health

Contact: Suzanne Wu
suzanne.wu@usc.edu
213-740-0252
University of Southern California

Public Release: 24-Oct-2013
Cell
Researchers design global HIV vaccine that shows promise in monkeys
The considerable diversity of HIV worldwide represents a critical challenge for designing an effective HIV vaccine. Now a scientific team led by Beth Israel Deaconess Medical Center has shown that mosaic antigens could be useful in the design of a global HIV vaccine.
Military HIV Research Program, National Institutes of Health, NIH/National Institute of Allergy and Infectious Diseases, Bill and Melinda Gates Foundation, Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, Harvard

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center

Public Release: 24-Oct-2013
Stroke: Journal of the American Heart Association
Hands-free ultrasound device with clot-busting drug safe for stroke patients
A hands-free ultrasound device combined with clot buster was safe for ischemic stroke patients. The hands-free ultrasound device could help open up more arteries and improve patient outcomes.
National Institutes of Health

Contact: Karen Astle
karen.astle@heart.org
214-706-1392
American Heart Association

Public Release: 23-Oct-2013
Cell Cycle
Study: Metformin for breast cancer less effective at higher glucose concentrations
A University of Colorado Cancer Center study published online this month in the journal Cell Cycle shows that breast cancer cell growth, motility and aggression is promoted by excess glucose, as experienced by patients with diabetes and metabolic syndrome. The study also showed that patients with high glucose may require higher doses of the drug metformin to achieve the same anti-cancer activity as patients with normal glucose levels.
NIH/National Cancer Institute, National Institutes of Health, Komen

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 23-Oct-2013
PLOS ONE
USC researcher learns how to break a sweat
Without sweat, we would overheat and die. In a recent paper in the journal PLOS ONE, USC faculty member Krzysztof Kobielak and a team of researchers explored the ultimate origin of this sticky, stinky but vital substance -- sweat gland stem cells.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Marie Rippen
lytal@med.usc.edu
University of Southern California - Health Sciences

Public Release: 23-Oct-2013
Journal of Clinical Investigation
Cancer wasting due in part to tumor factors that block muscle repair, study shows
A new study reveals that tumors release factors into the bloodstream that inhibit the repair of damaged muscle fibers, and that this contributes to muscle loss during cancer wasting. The condition, also called cancer cachexia, accompanies certain cancers, causes life-threatening loss of body weight and is responsible for up to one-in-four cancer deaths. The condition has no treatment. The study points to new strategies and new drug targets for treating cancer cachexia.
NIH/National Cancer Institute, NIH/Center for Clinical and Translational Science

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 23-Oct-2013
Nature
Researchers capture images of open channel that moves proteins across cell membranes
Similar to passengers on an urban transit system, every protein made in the cell has a specific destination and function. Channels in cell membranes help direct these proteins to their appropriate target. Researchers at Boston University School of Medicine and their colleagues have now captured images of these channels as they open to allow proteins to pass through a membrane, while the proteins are being made.
NIH/National Institute of General Medical Sciences

Contact: Jenny Eriksen Leary
jenny.eriksen@bmc.org
617-638-6841
Boston University Medical Center

Public Release: 23-Oct-2013
Anesthesiology
Neurotoxin effectively relieves bone cancer pain in dogs, Penn researchers find
By the time bone cancer is diagnosed in a pet dog, it is often too late to save the animal's life. Instead, the goal of treatment is to keep the dog as comfortable and free of pain as possible for as long as possible. A study by University of Pennsylvania veterinarians Dorothy Cimino Brown and Kimberly Agnello has demonstrated that a single spinal injection of a neurotoxin provided more relief from pain than the pain-relieving drugs that are typically used.
NIH/National Institute of Mental Health

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania

Public Release: 23-Oct-2013
Clinical Cancer Research
A simple test may catch early pancreatic cancer
Reporting on a small preliminary study, Johns Hopkins researchers say a simple blood test based on detection of tiny epigenetic alterations may reveal the earliest signs of pancreatic cancer, a disease that is nearly always fatal because it isn't usually discovered until it has spread to other parts of the body.
National Cancer Institute, NIH/National Institute of Environmental Health Sciences

Contact: Stephanie Desmon
sdesmon1@jhmi.edu
410-955-8665
Johns Hopkins Medicine

Public Release: 23-Oct-2013
Bradley Hasbro Children's Research Center launches food allergy video game trial
Elizabeth McQuaid, Ph.D., a staff psychologist from the Bradley Hasbro Children's Research Center, is leading a research team testing a new interactive software game developed to help children with peanut allergies better manage allergy symptoms, social situations and proper food avoidance.
NIH/National Institute of Child Health & Human Development

Contact: Jill Reuter
jreuter@lifespan.org
401-444-6863
Lifespan

Public Release: 23-Oct-2013
Journal of Clinical Investigation
New eye treatment effective in laboratory tests
A promising technique for treating human eye disease has proven effective in preclinical studies and may lead to new treatments to prevent blindness, according to experiments conducted at The Scripps Research Institute in La Jolla, California. The studies involved controlling the actions of microRNAs, tiny pieces of RNA that were once considered to be "junk" but are now known to fine-tune gene activation and expression.
National Institutes of Health, Lowy Medical Research Institute, Manpei Suzuki Diabetes Foundation

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 23-Oct-2013
New England Journal of Medicine
Child born with HIV still in remission after 18 months off treatment, experts report
A three-year-old Mississippi child born with HIV and treated with a combination of antiviral drugs unusually early continues to do well and remains free of active infection 18 months after all treatment ceased, according to an updated case report published Oct. 23 in the New England Journal of Medicine.
National Institutes of Health, American Foundation for AIDS Research, International Maternal Pediatric Adolescent AIDS Clinical Trials Network, Collaboratory of AIDS Researchers for Eradication

Contact: Ekaterina Pesheva
epeshev1@jhmi.edu
410-502-9433
Johns Hopkins Medicine

Showing releases 3126-3150 out of 3465.

<< < 121 | 122 | 123 | 124 | 125 | 126 | 127 | 128 | 129 | 130 > >>

     
   

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