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Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 3151-3175 out of 3517.

<< < 122 | 123 | 124 | 125 | 126 | 127 | 128 | 129 | 130 | 131 > >>

Public Release: 8-Dec-2013
Nature Methods
Novel method could help bring cancer biomarkers to clinic
International study demonstrates protein-measurement technique's potential to standardize quantification of the entire human proteome.
National Institutes of Health, NIH/National Cancer Institute

Contact: Deborah Bach
media@fredhutch.org
206-667-2210
Fred Hutchinson Cancer Research Center

Public Release: 7-Dec-2013
55th American Society of Hematology Annual Meeting
Penn Medicine team reports on study of first 59 leukemia patients who received cell therapy
Three and a half years after beginning a clinical trial which demonstrated the first successful and sustained use of genetically engineered T cells to fight leukemia, a research team from the University of Pennsylvania will announce the latest data on 59 adults and children with advanced blood cancers that have failed to respond to standard therapies. Results in patients who received this investigational, personalized cellular therapy, known as CTL019, will be presented during the American Society of Hematology's Annual Meeting and Exposition.
NIH/National Cancer Institute, Leukemia and Lymphoma Society, Alliance for Cancer Gene Therapy, Novartis

Contact: Holly Auer
holly.auer@uphs.upenn.edu
215-200-2313
University of Pennsylvania School of Medicine

Public Release: 7-Dec-2013
55th American Society of Hematology Annual Meeting
International gene therapy trial for 'bubble boy' disease shows promising early results
Researchers reported promising outcomes data for the first group of boys with X-linked severe combined immunodeficiency syndrome, a fatal genetic immunodeficiency also known as "bubble boy" disease, who were treated in an international clinical study of a new form of gene therapy. The mechanism that delivered the gene therapy is designed to prevent the leukemia that arose a decade ago in a similar trial in Europe, when one-quarter of boys treated developed the blood cancer.
NIH/National Institute of Allergy & Infectious Diseases, NIH/National Heart Lung & Blood Institute

Contact: Irene Sege
irene.sege@childrens.harvard.edu
617-919-3110
Dana-Farber Cancer Institute

Public Release: 7-Dec-2013
Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities
Genetic mutations and molecular alterations may explain racial differences in head and neck cancers
A team of scientists at Johns Hopkins and in Texas has identified a handful of genetic mutations in black Americans, in addition to some chemical alterations affecting gene activity, which may help explain why the death rate among African-Americans from the most common form of head and neck cancer continues to hover some 18 percent higher above the death rate of whites with the same cancer.
NIH/National Cancer Institute, NIH/National Institute of Dental and Craniofacial Research

Contact: David March
dmarch1@jhmi.edu
410-955-1534
Johns Hopkins Medicine

Public Release: 6-Dec-2013
Archives of Psychiatric Nursing
To improve foster care, add a psychiatric nurse to treatment team
Mental health nurses are a valuable addition to the team that treats teens who have psychiatric problems and are in the foster care system.
NIH/National Institute of Mental Health

Contact: Nancy Solomon
solomonn@slu.edu
314-977-8017
Saint Louis University

Public Release: 6-Dec-2013
Proceedings of the National Academy of Sciences
Clinical waste may prove valuable for monitoring treatment response in ovarian cancer
A microchip-based device developed by Massachusetts General Hospital investigators may greatly simplify the monitoring of patients' response to treatment for ovarian cancer -- the most lethal form of gynecologic cancer -- and certain other malignancies. The team reports using their device to isolate and identify tumor cells from ascites, an accumulation of fluid in the abdomen that often occurs in abdominal cancers.
National Institutes of Health, US Department of Defense

Contact: Cassandra Aviles
cmaviles@partners.org
617-724-6433
Massachusetts General Hospital

Public Release: 6-Dec-2013
Blood
Promising results for Swedish cancer drug candidate
A new study conducted by scientists from the Dana-Farber Cancer Institute at Harvard Medical School and Karolinska Institutet, Sweden presents very promising results for the treatment of the cancer form multiple myeloma. The drug candidate used in the research has been developed by scientists from Karolinska Institutet in and a Swedish company following its initial identification at the same university. The findings are so promising that the scientists are teaming up with Harvard to bring the drug to clinical trials on patients.
Swedish Research Council, Swedish Cancer Society, Swedish Foundation for Strategic Research, National Institutes of Health, and others

Contact: The Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet

Public Release: 6-Dec-2013
Molecular Therapy
Penn study delivers protein across blood-brain barrier to degrade Alzheimer's plaques
University of Pennsylvania biologists substantially degraded Alzheimer's plaques in mice brains and human brain tissue by sending a fused protein across the blood-brain barrier. Their technique not only offers a potential strategy for treating the debilitating neurological disease, but also other diseases that affect the brain and eyes.
National Institutes of Health, Bill and Melinda Gates Foundation, Juvenile Diabetes Research Foundation, American Diabetes Association, American Heart Association, Research to Prevent Blindness

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania

Public Release: 6-Dec-2013
Journal of National Cancer Institute
Gut microbes may be a risk factor for colorectal cancer
In one of the largest epidemiological studies of human gut bacteria and colorectal cancer ever conducted, a team of researchers at NYU Langone Medical Center has found a clear association between gut bacteria and colorectal cancer. The study, published today in the Journal of the National Cancer Institute, discovered that colorectal cancer patients had fewer beneficial bacteria and more harmful bacteria than people without the disease.
National Institutes of Health

Contact: Lorinda Klein
lorindaann.klein@nyumc.org
212-404-3533
NYU Langone Medical Center / New York University School of Medicine

Public Release: 5-Dec-2013
Human Reproduction
Vaginally administered ED medication may alleviate menstrual cramping
Women with moderate to severe menstrual cramps may find relief in a class of erectile dysfunction drugs, according to a team of researchers led by Penn State College of Medicines Richard Legro.
National Institutes of Health

Contact: Matthew Solovey
msolovey@hmc.psu.edu
717-531-8606
Penn State

Public Release: 5-Dec-2013
Cancer Research
Prostate cancer biomarker may predict patient outcomes
Researchers at Vanderbilt University Medical Center and the University of Alberta in Canada have identified a biomarker for a cellular switch that accurately predicts which prostate cancer patients are likely to have their cancer recur or spread.
National Institutes of Health, Canadian Cancer Society Research Institute

Contact: Dagny Stuart
dagny.stuart@vanderbilt.edu
615-322-4747
Vanderbilt University Medical Center

Public Release: 5-Dec-2013
Structure
How our vision dims: Chemists crack the code of cataract creation
Groundbreaking new findings by UC Irvine and German chemists about how cataracts form could be used to help prevent the world's leading cause of blindness, which currently affects nearly 20 million people worldwide.
National Institutes of Health, Deutsche Forschungsgemeinschaft

Contact: Janet Wilson
janethw@uci.edu
949-824-3969
University of California - Irvine

Public Release: 5-Dec-2013
Cell Reports
Gene found to be crucial for formation of certain brain circuitry
Using a powerful gene-hunting technique for the first time in mammalian brain cells, researchers at Johns Hopkins report they have identified a gene involved in building the circuitry that relays signals through the brain. The gene is a likely player in the aging process in the brain, the researchers say.
Howard Hughes Medical Institute, NIH/National Institute of Mental Health

Contact: Shawna Williams
shawna@jhmi.edu
443-903-7607
Johns Hopkins Medicine

Public Release: 5-Dec-2013
Public Health
More alcohol and traffic laws mean fewer traffic deaths, NYU Steinhardt study concludes
States with a higher number of alcohol- and traffic-related laws have a lower proportion of traffic deaths than do states with fewer such laws on the books, a study by researchers at NYU's Steinhardt School of Culture, Education, and Human Development has found.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: James Devitt
james.devitt@nyu.edu
212-998-6808
New York University

Public Release: 5-Dec-2013
Cell Stem Cell
Activating pathway could restart hair growth in dormant hair follicles, Penn Study suggests
A pathway known for its role in regulating adult stem cells has been shown to be important for hair follicle proliferation, but contrary to previous studies, is not required within hair follicle stem cells for their survival, according to researchers at the University of Pennsylvania. A new study, published in Cell Stem Cell, identifies a molecular pathway that can be activated to prompt hair growth of dormant hair follicles, or blocked to prevent growth of unwanted hair.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Kim Menard
kim.menard@uphs.upenn.edu
215-662-6183
University of Pennsylvania School of Medicine

Public Release: 5-Dec-2013
Stem Cells
Priming 'cocktail' shows promise as cardiac stem cell grafting tool
Researchers have identified a new tool that could help facilitate future stem cell therapy for the more than 700,000 Americans who suffer a heart attack each year.
National Institutes of Health

Contact: Jennifer Nachbur
jennifer.nachbur@uvm.edu
802-656-7875
University of Vermont

Public Release: 5-Dec-2013
Science
Vaccine study reveals link between immunity and cells' starvation response
Scientists studying immune responses to the yellow fever vaccine have identified a gene whose activation in key immune cells is a sign of a robust response. The results suggest vaccine components that activate the GCN2 gene could provide long-lasting immunity.
NIH/National Institute of Allergy and Infectious Diseases, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Bill & Melinda Gates Foundation

Contact: Quinn Eastman
qeastma@emory.edu
404-727-7829
Emory Health Sciences

Public Release: 5-Dec-2013
Cell
Probiotic therapy alleviates autism-like behaviors in mice
Autism spectrum disorder (ASD) is diagnosed when individuals exhibit characteristic behaviors, decreased social interactions, and impaired communication. Curiously, many with ASD also suffer from gastrointestinal issues, like abdominal cramps and constipation. Guided by this co-occurrence of brain and gut problems, researchers at the California Institute Technology are investigating a bacterium that alleviates GI and behavioral symptoms in autistic-like mice, introducing a potentially transformative probiotic therapy for autism and other neurodevelopmental disorders.
NIH/National Institute of Mental Health

Contact: Deborah Williams-Hedges
mr@caltech.edu
626-395-3227
California Institute of Technology

Public Release: 5-Dec-2013
Immunity
Sanford-Burnham researchers identify new target to treat psoriasis
The study identifies the BTLA inhibitory receptor as the key factor in limiting inflammatory responses, particularly in skin. The study has important implications for developing drugs to treat psoriasis and potentially other inflammatory and autoimmune diseases.
National Institutes of Health

Contact: Susan Gammon
sgammon@sanfordburnham.org
858-795-5012
Sanford-Burnham Medical Research Institute

Public Release: 5-Dec-2013
Cell
Membrane enzymes 'stop and frisk' proteins indiscriminately
For what is believed to be the first time, researchers at The Johns Hopkins University have illuminated the inner workings of an important class of enzymes located inside the outer envelopes of cells. Much to their surprise, they report, these protein cutters, called rhomboid proteases, are entirely different than nearly every other type of enzyme studied, showing no attraction to the proteins they cut and being extremely slow in making their cuts.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Vanessa McMains
vmcmain1@jhmi.edu
410-502-9410
Johns Hopkins Medicine

Public Release: 5-Dec-2013
BMJ Open
Eating healthy vs. unhealthy diet costs about $1.50 more per day
The healthiest diets cost about $1.50 more per day than the least healthy diets, according to new research from Harvard School of Public Health. The finding is based on the most comprehensive examination to date comparing prices of healthy foods and diet patterns vs. less healthy ones.
NIH/Heart, Lung and Blood Institute, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Harvard School of Public Health

Contact: Marge Dwyer
mhdwyer@hsph.harvard.edu
617-432-8416
Harvard School of Public Health

Public Release: 5-Dec-2013
Science
Brain cancer cells hide while drugs seek
A team of scientists, led by principal investigator Paul S. Mischel, M.D., a member of the Ludwig Institute for Cancer Research and professor in the Department of Pathology at the University of California, San Diego School of Medicine, has found that brain cancer cells resist therapy by dialing down the gene mutation targeted by drugs, then re-amplify that growth-promoting mutation after therapy has stopped.
The Ben and Catherine Ivy Foundation Fund, National Institutes of Health

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 5-Dec-2013
Cell
How mosquitoes are drawn to human skin and breath
Scientists at the University of California, Riverside have found that the very receptors in the mosquito's maxillary palp that detect carbon dioxide are ones that detect skin odors as well, thus explaining why mosquitoes are attracted to skin odor -- smelly socks, worn clothes, bedding -- even in the absence of carbon dioxide. Using a chemical computational method they developed, the researchers identified affordable, safe and pleasant-smelling compounds that could find use in mosquito control.
NIH/National Institute of Allergy and Infectious Diseases, National Science Foundation, University of California Global Health Institute, Bill and Melinda Gates Foundation

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside

Public Release: 5-Dec-2013
Journal of General Internal Medicine
Tracking exercise as vital sign associated with weight loss and better glucose control for patients
Asking patients about their exercise habits was associated with weight loss in overweight patients and improved glucose control for patients with diabetes, according to a recently published study in the Journal of General Internal Medicine.
Centers for Disease Control and Prevention, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Kaiser Permanente Northern California Division of Research

Contact: Joshua Weisz
jweisz@golinharris.com
202-585-2614
Kaiser Permanente

Public Release: 5-Dec-2013
Science
TSRI scientists: Emerging bird flu strain is still poorly adapted for infecting humans
Avian influenza virus H7N9, which killed several dozen people in China earlier this year, has not yet acquired the changes needed to infect humans easily, according to a new study by scientists at The Scripps Research Institute. In contrast to some initial studies that had suggested that H7N9 poses an imminent risk of a global pandemic, the new research found, based on analyses of virus samples from the Chinese outbreak, that H7N9 is still mainly adapted for infecting birds, not humans.
National Institutes of Health, The Scripps Research Institute/Skaggs Institute for Chemical Biology, Centers for Disease Control and Prevention, Netherlands Organization for Scientific Research

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Showing releases 3151-3175 out of 3517.

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