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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3151-3175 out of 3403.

<< < 122 | 123 | 124 | 125 | 126 | 127 | 128 | 129 | 130 | 131 > >>

Public Release: 15-May-2013
2013 ASCO Annual Meeting
First prospective trial shows molecular profiling timely for tailoring therapy
CUSTOM is the first completed prospective clinical trial that used genetic analysis alone to assign cancer treatment for patients with one of three different cancers. Findings suggest patients, and their physicians, are eager to jump into next-era cancer care -- analysis of an individual's tumor to find and target genetic mutations that drive the cancer.
NIH/National Cancer Institute

Contact: Karen Mallet
Georgetown University Medical Center

Public Release: 15-May-2013
Journal of Clinical Investigation
Researchers identify signals that direct the immune system to reject a transplanted organ
In this issue of the Journal of Clinical Investigation, Fadi Lakkis and colleagues at the University of Pittsburgh used mice to identify signals that direct immune cells towards a transplanted organ.
National Institutes of Health

Contact: Jillian Hurst
Journal of Clinical Investigation

Public Release: 15-May-2013
Journal of Clinical Investigation
Hot on the TRAIL of graft vs. host disease
In this issue of the Journal of Clinical Investigation, Arnab Ghosh and colleagues at Memorial Sloan-Kettering Cancer Center found that expression of a protein that causes cell death, TRAIL, in transplanted cells was critical for an effective anti-tumor response.
National Institutes of Health, US Department of Defense, Radiation Effects Research Foundation

Contact: Jillian Hurst
Journal of Clinical Investigation

Public Release: 14-May-2013
Early Human Development
Massage therapy shown to improve stress response in preterm infants
A study published recently in Early Human Development, conducted by University of Louisville School of Nursing researcher Sandra Smith, Ph.D., and her team at the University of Utah, found massage therapy that involved moderate pressure and stroking of the soft tissues followed by flexing and extending the joints of the arms and legs increased heart rate variability in male, but not in female preterm infants.
National Institutes of Health, University of Utah/Interdisciplinary Research Committee

Contact: Julie Heflin
University of Louisville

Public Release: 14-May-2013
Genes & Development
Study IDs key protein for cell death
Findings may offer a new way to kill cancer cells by forcing them into an alternative programmed-death pathway.
National Institutes of Health, American Cancer Society

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 14-May-2013
Newly described type of immune cell and T cells share similar path to maturity
Innate lymphoid cells protect boundary tissues such as the skin, lung, and the gut from microbial onslaught. They also have shown they play a role in inflammatory disease. Researchers have found that maturation of ILC2s requires T-cell factor 1 to move forward. They describe in Immunity that one mechanism used to build ILCs is the same as that in T cells.
National Institutes of Health

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 14-May-2013
Advanced Materials
Using clay to grow bone
In new research published online May 13, 2013 in Advanced Materials, researchers from Brigham and Women's Hospital are the first to report that synthetic silicate nanoplatelets (also known as layered clay) can induce stem cells to become bone cells without the need of additional bone-inducing factors.
National Institutes of Health

Contact: Marjorie Montemayor-Quellenberg
Brigham and Women's Hospital

Public Release: 14-May-2013
Clinical Cancer Research
New drug enhances radiation treatment for brain cancer in preclinical studies
A novel drug may help increase the effectiveness of radiation therapy for the most deadly form of brain cancer, report scientists at Virginia Commonwealth University Massey Cancer Center. In mouse models of human glioblastoma multiforme, the new drug helped significantly extend survival when used in combination with radiation therapy.
NIH/National Cancer Institute

Contact: John Wallace
Virginia Commonwealth University

Public Release: 14-May-2013
Circulation: Cardiovascular Quality and Outcomes
What impacts whether African Americans call 9-1-1 immediately for stroke symptoms?
African-Americans know the signs of stroke, but concerns about medical cost, ambulance response time and unfamiliarity with the need for prompt hospital care impacted whether they called 9-1-1 immediately.
NIH/National Institutes of Neurological Disorders and Stroke

Contact: Shantell Kirkendoll
University of Michigan Health System

Public Release: 14-May-2013
Journal of General Internal Medicine
Primary care physicians vital to complete care of prostate cancer patients
Androgen deprivation therapy is a common and effective treatment for advanced prostate cancer. Among other side-effects, it can cause bone thinning in men on long-term treatment. However, a new study finds that testing is not routine. The authors noted that men were more likely to be tested when they were being cared for by both a urologist and a primary care physician. Their paper appears in the Journal of General Internal Medicine, published by Springer.
NIH/National Cancer Institute, American Cancer Society

Contact: Joan Robinson

Public Release: 14-May-2013
University of Maryland Medical Center launches genetic-testing program for cardiac patients
Patients with coronary artery disease who undergo treatment at the University of Maryland Medical Center now can receive long-term therapy based on information found in their genes. As part of a new personalized medicine initiative, the medical center is offering genetic testing to help doctors determine which medication a patient should take after a stenting procedure in order to prevent blood clots that could lead to serious -- and potentially fatal -- heart attacks and strokes.
National Institutes of Health

Contact: Karen Warmkessel
University of Maryland Medical Center

Public Release: 14-May-2013
Clinical Breast Cancer
Cognitive training improves executive function in breast cancer survivors
Women whose breast cancer had been treated with chemotherapy demonstrated improved executive function, such as cognitive flexibility, verbal fluency and processing speed after using exercises developed by Lumosity, the leading online cognitive training program. The study also found significant improvement in self-reported measures of everyday executive function and observed some transfer to verbal memory.
NIH/National Institute of Health New Innovator Award

Contact: Erica Perng

Public Release: 14-May-2013
Society of Biological Psychiatry 68th Annual Scientific Convention
Molecular Psychiatry
Brain-imaging study links cannabinoid receptors to post-traumatic stress disorder
In a first-of-its-kind effort to illuminate the biochemical impact of trauma, researchers at NYU Langone Medical Center have discovered a connection between the quantity of cannabinoid receptors in the human brain, known as CB1 receptors, and post-traumatic stress disorder, the chronic, disabling condition that can plague trauma victims with flashbacks, nightmares and emotional instability.
National Institutes of Health

Contact: Lorinda Klein
NYU Langone Medical Center / New York University School of Medicine

Public Release: 13-May-2013
Proceedings of the National Academy of Sciences
Alligator stem cell study gives clues to tooth regeneration
Alligators may help scientists learn how to stimulate tooth regeneration in people, according to new research led by the Keck School of Medicine of the University of Southern California (USC). For the first time, a global team of researchers led by USC pathology Professor Cheng-Ming Chuong, M.D., Ph.D., has uncovered unique cellular and molecular mechanisms behind tooth renewal in American alligators.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Alison Trinidad
University of Southern California - Health Sciences

Public Release: 13-May-2013
Proceedings of the National Academy of Sciences
Tumor-activated protein promotes cancer spread
Researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center report that cancers physically alter cells in the lymphatic system -- a network of vessels that transports and stores immune cells throughout the body -- to promote the spread of disease, a process called metastasis.
National Institutes of Health, US Department of Defense, NIH/National Cancer Institute

Contact: Scott LaFee
University of California - San Diego

Public Release: 13-May-2013
Proceedings of the National Academy of Sciences
Circadian clock gene rhythms in brain altered in depression, UC Irvine Health study finds
UC Irvine Health researchers have helped discover that genes controlling circadian clock rhythms are profoundly altered in the brains of people with severe depression. These clock genes regulate 24-hour circadian rhythms affecting hormonal, body temperature, sleep and behavioral patterns.
Pritzker Neuropsychiatric Disorders Research Fund, NIH/National Institute of Mental Health

Contact: Tom Vasich
University of California - Irvine

Public Release: 13-May-2013
Cancer Cell
Researchers discover master regulator that drives majority of lymphoma
A soon-to-be-tested class of drug inhibitors were predicted to help a limited number of patients with B-cell lymphomas with mutations affecting the EZH2 protein. However, a research team, led by investigators at Weill Cornell Medical College, now report that these agents may, in fact, help a much broader cross section of lymphoma patients.
Burroughs Wellcome Foundation & Chemotherapy Foundation, NIH/National Cancer Institute Physical Sciences

Contact: John Rodgers
Weill Cornell Medical College

Public Release: 13-May-2013
Journal of Neuroscience
Grammar errors? The brain detects them even when you are unaware
Your brain often works on autopilot when it comes to grammar. That theory has been around for years, but University of Oregon neuroscientists have captured elusive hard evidence that people indeed detect and process grammatical errors with no awareness of doing so.
NIH/National Institute on Deafness and Other Communication Disorders

Contact: Jim Barlow
University of Oregon

Public Release: 13-May-2013
Journal of Clinical Oncology
Study identifies possible new acute leukemia marker, treatment target
A study has identified microRNA-155 as a new independent prognostic marker and treatment target in patients with acute myeloid leukemia that has normal-looking chromosomes under the microscope (that is, cytogenetically normal acute myeloid leukemia). The findings suggest that this molecule is important in leukemia development and should be targeted by a drug that will inhibit it.
NIH/National Cancer Institute, Coleman Leukemia Research Foundation, Pelotonia Fellowship Program

Contact: Darrell E. Ward
Ohio State University Wexner Medical Center

Public Release: 13-May-2013
Bix of Sanders-Brown receives NIH funding for stroke research
The new funding from the NIH will enable Bix and his team to investigate the effects of a newly identified stroke treatment on brain tissue regeneration, to investigate factors influencing generation and survival of post-stroke generated neurons, and to investigate novel mechanisms in neuritogenesis and neurite extension. The ultimate aim of this work is to develop a novel stroke therapy for humans.
National Institutes of Health

Contact: Allison Elliott
University of Kentucky

Public Release: 13-May-2013
Proceedings of the National Academy of Sciences
Out of sync with the world: Body clocks of depressed people are altered at cell level
Every cell in our bodies runs on a 24-hour clock, tuned to the night-day, light-dark cycles that have ruled us since the dawn of humanity. But new research shows that the clock may be broken in the brains of people with depression -- even at the level of the gene activity inside their brain cells.
Neuropsychiatric Disorders Research Fund, NIH/National Institute of Mental Health, Brain & Behavior Research Foundation, Office of Naval Research

Contact: Kara Gavin
University of Michigan Health System

Public Release: 12-May-2013
Nature Immunology
Mutation causing wrong-way plumbing explains 1 type of blue-baby syndrome
Total anomalous pulmonary venous connection, one type of "blue baby" syndrome, is a potentially deadly congenital disorder that occurs when pulmonary veins don't connect normally to the left atrium of the heart. TAPVC babies are born cyanotic from lack of oxygen. Semaphorin 3d guides the development of endothelial cells and is crucial for normal development of pulmonary veins. Mutations in Sema3d cause embryonic blood vessels to hook up in the wrong way.
National Institutes of Health

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 12-May-2013
Nature Chemical Biology
Research on cilia heats up: Implications for hearing, vision loss and kidney disease
Experiments at Johns Hopkins have unearthed clues about which protein signaling molecules are allowed into hollow, hair-like "antennae," called cilia, that alert cells to critical changes in their environments.
NIH/National Institute of General Medical Sciences, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, NIH/National Institute of Neurological Disorders and Stroke, NIH/National Cancer Institute

Contact: Catherine Kolf
Johns Hopkins Medicine

Public Release: 12-May-2013
Non-inherited mutations account for many heart defects, Yale researchers find
New mutations that are absent in parents but appear in their offspring account for at least 10 percent of severe congenital heart disease, reveals a massive genomics study led, in part, by researchers at the Yale School of Medicine.
National Institutes of Health

Contact: Bill Hathaway
Yale University

Public Release: 12-May-2013
Nature Genetics
Penn Medicine researchers identify 4 new genetic risk factors for testicular cancer
A new study in Nature Genetics looking at the genomes of more than 13,000 men identified four new genetic variants associated with an increased risk of testicular cancer, the most commonly diagnosed type in young men today.
NIH/National Cancer Institute

Contact: Steve Graff
University of Pennsylvania School of Medicine

Showing releases 3151-3175 out of 3403.

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