Public Release: 5-Dec-2011
Genome Research
Pharmacogenomics study finds rare gene variants critical for personalized drug treatment
The use of genetic tests to predict a patient's response to drugs is increasingly important in the development of personalized medicine. But genetic tests often only look for the most common gene variants. In a study published online in Genome Research, researchers have characterized rare genetic variants in a specific gene that can have a significant influence in disposition of a drug used to treat cancer and autoimmune disease.
NIH/National Institute of General Medical Sciences, NIH/National Cancer Institute, NIH/National Institute of Child Health and Human Development, American Lebanese Syrian Associated Charities

Public Release: 5-Dec-2011
Proceedings of the National Academy of Sciences
Rice as a source of arsenic exposure
A study by a Dartmouth team of scientists advances our understanding of the sources of human exposure to arsenic and focuses attention on the potential for consuming harmful levels of arsenic via rice.
NIH/National Institute for Environmental Health Sciences, National Institutes of Health, NIH/National Cancer Institute, US Environmental Protection Agency

Public Release: 4-Dec-2011
Nature
Senses of sophistication: Mosquitoes detect subtle cues finding food, spreading diseases
Researchers from Boston College and Brandeis University have unraveled the mystery as to how the malaria mosquito uses its sensory powers to find food and spread disease.
National Science Foundation, National Institute of Mental Health, NIH/National Institute of Neurological Disorders, Boston College

Public Release: 4-Dec-2011
Nature Genetics
New gene study of ADHD points to defects in brain signaling pathways
Pediatric researchers analyzing genetic influences in attention-deficit/hyperactivity disorder have found alterations in specific genes involved in important brain signaling pathways. The study raises the possibility that drugs acting on those pathways might offer a new treatment option for patients with ADHD who have those gene variants -- potentially, half a million US children.
National Institutes of Health