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Department of Health and Human Services

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Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3176-3200 out of 3574.

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Public Release: 12-Mar-2014
72nd Annual Scientific Meeting of the American Psychosomatic Society
Study: Response to emotional stress may be linked to some women's heart artery dysfunction
Researchers at the Barbra Streisand Women's Heart Center at the Cedars-Sinai Heart Institute have found that emotional stressors -- such as those provoking anger -- may cause changes in the nervous system that controls heart rate and trigger a type of coronary artery dysfunction that occurs more frequently in women than men. They will describe their findings at the American Psychosomatic Society's annual meeting on March 13 in San Francisco.
NIH/National Heart, Lung and Blood Institute, NIH/National Institute on Aging, General Clinical Research Center's Clinical Research Feasibility Funds, National Center for Advancing Translational Sciences, and others

Contact: Sally Stewart
Cedars-Sinai Medical Center

Public Release: 12-Mar-2014
Journal of the American Heart Association
Gestational diabetes linked to increased risk for heart disease in midlife
Women who experience gestational diabetes may face an increased risk of early heart disease later in life, even if they do not develop type 2 diabetes or metabolic syndrome subsequent to their pregnancy, according to a Kaiser Permanente study published today in the Journal of the American Heart Association.
National Institutes of Health

Contact: Jennifer Schell
Kaiser Permanente

Public Release: 12-Mar-2014
Nature Structural & Molecular Biology
Protein key to cell motility has implications for stopping cancer metastasis
A Penn team describes how a key cell-movement protein called IRSp53 is regulated in a resting and active state, and what this means for cancer-cell metastasis. They characterized how IRSp53 connects to the cell-motility machinery by starting the formation of cell filopodia.
National Institutes of Health, American Cancer Society

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 12-Mar-2014
Cell Host & Microbe
Microbes help to battle infection
Caltech researchers found that beneficial gut bacteria are necessary for the development of innate immune cells -- specialized types of white blood cells that serve as the body's first line of defense against invading pathogens.
National Institutes of Health, Burroughs Wellcome Fund

Contact: Deborah Williams-Hedges
California Institute of Technology

Public Release: 12-Mar-2014
Mayo Clinic Proceedings
Large waist linked to poor health, even among those in healthy body mass index ranges
Having a big belly has consequences beyond trouble squeezing into your pants. It's detrimental to your health, even if you have a healthy body mass index, a new international collaborative study led by a Mayo Clinic researcher found. Men and women with large waist circumferences were more likely to die younger, and were more likely to die from illnesses such as heart disease, respiratory problems, and cancer after accounting for body mass index, smoking, alcohol use and physical activity.
NIH/National Cancer Institute

Contact: Nick Hanson
Mayo Clinic

Public Release: 12-Mar-2014
Journal of Adolescent Health
Hasbro Children's Hospital study finds texting program good option for teen girls' health
Megan Ranney, M.D., M.P.H., an emergency medicine attending physician at Hasbro Children's Hospital, recently led a study that found a text-message program may be an effective violence prevention tool for at-risk teen girls. The study has been published online in the Journal of Adolescent Health.
Society for Academic Emergency Medicine, National Institutes of Health

Contact: Jill Reuter

Public Release: 12-Mar-2014
JAMA Psychiatry
Nicotine withdrawal weakens brain connections tied to self-control over cigarette cravings
A new brain imaging study in this week's JAMA Psychiatry from scientists in Penn Medicine and the National Institute on Drug Abuse Intramural Research Program shows how smokers suffering from nicotine withdrawal may have more trouble shifting from a key brain network -- known as default mode, when people are in a so-called 'introspective' state -- and into a control network that could help exert more self-control over cravings and to focus on quitting for good.
NIH/National Cancer Institute, NIH/National Institute on Drug Abuse

Contact: Steve Graff
University of Pennsylvania School of Medicine

Public Release: 12-Mar-2014
Cell Host & Microbe
Newly diagnosed Crohn's disease patients show imbalance in intestinal microbial population
A multi-institutional study has identified how the intestinal microbial population of newly diagnosed Crohn's disease patients differs from that of individuals free of inflammatory bowel disease. The researchers found that Crohn's patients showed increased levels of harmful bacteria and reduced levels of the beneficial bacteria usually found in a healthy gastrointestinal tract.
Crohn's and Colitis Foundation, Helmsley Charitable Trust, Army Research Organization, National Institutes of Health

Contact: Kristen Chadwick
Massachusetts General Hospital

Public Release: 12-Mar-2014
JAHA: Journal of the American Heart Association
Gestational diabetes may raise risk for heart disease in midlife
Pregnant women may face an increased risk of early heart disease if they develop gestational diabetes. Early screening and intervention is important to identify later heart disease risk for these mothers, researchers said.
National Institutes of Health, Kaiser Permanente Community Benefit Program

Contact: Karen Astle
American Heart Association

Public Release: 12-Mar-2014
Building new drugs just got easier
Scientists at the Scripps Research Institute have developed a method for modifying organic molecules that significantly expands the possibilities for developing new pharmaceuticals and improving old ones.
NIH/National Institute of General Medical Sciences

Contact: Mika Ono
Scripps Research Institute

Public Release: 12-Mar-2014
IRX3 is likely the 'fat gene'
Mutations within the gene FTO have been implicated as the strongest genetic determinant of obesity risk in humans, but the mechanism behind this link remained unknown. Now, scientists have discovered that the obesity-associated elements within FTO interact with IRX3, a distant gene on the genome that appears to be the functional obesity gene. The FTO gene itself appears to have only a peripheral effect on obesity. The study appears online March 12 in Nature.
National Institutes of Health

Contact: Kevin Jiang
University of Chicago Medical Center

Public Release: 11-Mar-2014
Imbalanced hearing is more than a mild disability
Researchers at Washington University School of Medicine in St. Louis have received a five-year, $3 million grant from the National Institutes of Health to study the effects of asymmetric hearing loss in adults and children.
National Institutes of Health, Cochlear Americans

Contact: Julia Evangelou Strait
Washington University School of Medicine

Public Release: 11-Mar-2014
Discrepancies in clinical trial reporting raise questions of accuracy
In a Yale School of Medicine analysis of 96 research trial results published in top journals, almost all had at least one discrepancy between what was reported on the public clinical trial registry and what was posted in the journal article. Published in the March 12 issue of JAMA, the research letter raises serious questions about the accuracy of results reporting in both clinical trial registries and publications, and the importance of consistent presentation of accurate results.
NIH/National Heart, Lung, and Blood Institute, NIH/National Institute on Aging, American Federation for Aging Research

Contact: Karen N. Peart
Yale University

Public Release: 11-Mar-2014
American Journal of Transplantation
Finding hiding place of virus could lead to new treatments
Discovering where a common virus hides in the body has been a long-term quest for scientists. Up to 80 percent of adults harbor the human cytomegalovirus, which can cause severe illness and death in people with weakened immune systems. Now, researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine report that stem cells that encircle blood vessels can be a hiding place, suggesting a potential treatment target.
National Institutes of Health

Contact: Karen Richardson
Wake Forest Baptist Medical Center

Public Release: 11-Mar-2014
Human Molecular Genetics
Scientists from Penn and CHOP confirm link between missing DNA and birth defects
A team from the University of Pennsylvania and the Children's Hospital of Philadelphia has identified the genetic basis for a particular human syndrome that involves cleft palate, epilepsy and respiratory difficulties.
National Institutes of Health

Contact: Katherine Unger Baillie
University of Pennsylvania

Public Release: 11-Mar-2014
Stroke: Journal of the American Heart Association
Substance naturally found in humans is effective in fighting brain damage from stroke
A molecular substance that occurs naturally in humans and rats was found to 'substantially reduce' brain damage after an acute stroke and contribute to a better recovery, according to a newly released animal study by researchers at Henry Ford Hospital. The study, published online before print in Stroke, the journal of the American Heart Association, was the first ever to show that the peptide AcSDKP provides neurological protection when administered one to four hours after the onset of an ischemic stroke.
National Institutes of Health

Contact: Dwight Angell
Henry Ford Health System

Public Release: 11-Mar-2014
Journal of Pediatric Oncology Nursing
Lack of sleep, stress describe a mother's experience after child's ALL treatment
Many months after their child's diagnosis and treatment, 46 percent of mothers exhibited symptoms of clinical anxiety and 26 percent of mothers showed depressive symptoms.
NIH/National Cancer Institute

Contact: Garth Sundem
University of Colorado Denver

Public Release: 11-Mar-2014
Journal of Nursing Administration
Magnet hospitals have higher quality of care, NYU researcher finds
Research from NYU College of Nursing and the U of Penn School of Nursing provides insight on the factors contributing to the differences between Magnet and Non-Magnet hospitals as well as an analysis of the links between Magnet Recognition and better nurse-reported quality of care.
NIH/National Institute of Nursing Research, Robert Wood Johnson Foundation

Contact: Christopher James
New York University

Public Release: 11-Mar-2014
Psychological Science
Gesturing with hands is a powerful tool for children's math learning
Children who use their hands to gesture during a math lesson gain a deep understanding of the problems they are taught, according to new research from University of Chicago's Department of Psychology.
National Institutes of Health, National Science Foundation

Contact: Jann Ingmire
University of Chicago

Public Release: 11-Mar-2014
Cell Reports
Cellular alchemy: Penn study shows how to make insulin-producing cells from gut cells
Introducing three proteins that control the regulation of DNA in the nucleus -- called transcription factors -- into an immune-deficient mouse turned a specific group of cells in the gut lining into beta-like cells, raising the prospect of using differentiated pancreatic cells as a source for new beta cells.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 11-Mar-2014
Antibody could be used to target tumor-causing protein, study shows
Cincinnati Cancer Center and University of Cincinnati Cancer Institute researchers have found in a phase-1 study that patients with advanced melanoma and kidney cancer who were treated with a certain antibody that targets a tumor-enhancing protein was safe, which could lead to more treatment options for patients.
Genzyme Corporation, NIH/National Cancer Institute

Contact: Katie Pence
University of Cincinnati Academic Health Center

Public Release: 11-Mar-2014
American Journal of Pathology
Higher levels of CSF alpha-synuclein predict faster cognitive loss in Parkinson's disease
The course of Parkinson's disease can vary from gradual deterioration to precipitous decline in motor or cognitive function. Therefore identifying predictors of progression can benefit understanding of PD disease progression and impact management. Data from 304 PD patients followed for up to eight years indicate that patients with higher cerebrospinal fluid alpha-synuclein levels experienced faster cognitive decline in the following months, although no associations were found between alpha-synuclein levels and motor changes. The results are published in the American Journal of Pathology.
Michael J. Fox Foundation, Parkinson Study Group, and National Institutes of Health

Contact: Eileen Leahy
Elsevier Health Sciences

Public Release: 11-Mar-2014
Proceedings of the National Academy of Sciences
Cancer cells don't take 'drunken' walks through the body
Biologists have believed that cancers cells spread through the body in a slow, aimless fashion, resembling a drunk who can't walk straight. They now know that's true in a flat petri dish, but not in the three-dimensional space of an actual body.
National Institutes of Health

Contact: Phil Sneiderman
Johns Hopkins University

Public Release: 11-Mar-2014
Cerebral Cortex
A new cell type is implicated in epilepsy caused by traumatic brain injury
Traumatic brain injury is a risk factor for epilepsy, though the relationship is not understood. A new study published in Oxford Journals' Cerebral Cortex identifies increased levels of a specific neurotransmitter as a contributing factor. The findings suggest that damage to a specific type of brain cell plays a role in the development of epilepsy after a traumatic brain injury.
The Epilepsy Foundation, NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute of General Medical Sciences, NIH/National Institute on Aging, Cure Alzheimer's Fund

Contact: Siobhan Gallagher
Tufts University, Health Sciences Campus

Public Release: 11-Mar-2014
Public Health Reports
Prescriptions for opioids stabilizing after fivefold increase in 10-year span
To support the appropriate use of opioids and inform public health interventions to prevent drug abuse, most states have implemented a prescription drug monitoring program (PDMP). Researchers at Columbia University's Mailman School of Public Health evaluated the impact of these state-wide programs and found that after tripling until 2007, annual rates of prescriptions for opioid analgesics have stabilized although the effects of PDMPs on opioid dispensing vary markedly by state.
NIH/National Institute on Drug Abuse

Contact: Stephanie Berger
Columbia University's Mailman School of Public Health

Showing releases 3176-3200 out of 3574.

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