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News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3176-3200 out of 3609.

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Public Release: 15-May-2014
New tool to grow cancer cells streamlines laboratory research
A new technique that allows the growth of both normal and cancer cells and keeps them alive indefinitely is transforming and expediting basic cancer research. 'We've had a glimpse of how these cells can provide an amazing advance in human cancer clinical research in preliminary work, and now we demonstrate how incredibly useful they are in laboratory cancer research,' says the lead researcher.
National Institutes of Health

Contact: Karen Teber
Georgetown University Medical Center

Public Release: 15-May-2014
PLOS Genetics
Complex interactions may matter most for longevity
A new study of the biology of aging shows that complex interactions among diet, mitochondrial DNA and nuclear DNA appear to influence lifespan at least as much as single factors alone. The findings may help scientists better understand the underlying mechanisms of aging and explain why studies of single factors sometimes produce contradictory results.
National Institutes of Health

Contact: David Orenstein
Brown University

Public Release: 14-May-2014
Journal of Visualized Experiments
SapC-DOPS technology may help with imaging brain tumors, research shows
The Cincinnati Cancer Center and University of Cincinnati Cancer Institute research studies published in an April online issue of the Journal of Magnetic Resonance Imaging and a May issue of the Journal of Visualized Experiments reveal possibly new ways to image glioblastoma multiforme tumors -- a form of brain tumor -- using the SapC-DOPS technology.
Mayfield Education and Research Foundation, New Drug State Key Project, NIH/National Cancer Institute

Contact: Katie Pence
University of Cincinnati Academic Health Center

Public Release: 14-May-2014
Journal of American College of Cardiology
Research shows hope for normal heart function in children with fatal heart disease
After two decades of arduous research, a National Institutes of Health-funded investigator at the Children's Hospital of Michigan at the Detroit Medical Center and the Wayne State University School of Medicine has published a new study showing that many children with an often fatal type of heart disease can recover 'normal size and function' of damaged sections of their hearts.
National Institutes of Health

Contact: Julie O'Connor
Wayne State University - Office of the Vice President for Research

Public Release: 14-May-2014
Researchers ID changes that may occur in neural circuits due to cocaine addiction
This is the first study to demonstrate the critical links between the levels of the trafficking protein, the potassium channels' effect on neuronal activity and a mouse's response to cocaine. Results from the study are published in the peer-reviewed journal Neuron earlier this month.
NIH/National Institute on Drug Abuse, Salk Institute, Chapman Foundation

Contact: Sid Dinsay
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 14-May-2014
Science Translational Medicine
Hitting a moving target
A vaccine or other therapy directed at a single site on a surface protein of HIV could in principle neutralize nearly all strains of the virus -- thanks to the diversity of targets the site presents to the human immune system.
International AIDS Vaccine Initiative, National Institutes of Health, Canadian Institutes of Health, Gates Foundation

Contact: Mika Ono
Scripps Research Institute

Public Release: 14-May-2014
Journal of Experimental Biology
Scientists investigate the role of the 'silent killer' inside deep-diving animals
Scientists at Scripps Institution of Oceanography at UC San Diego and Sonoma State University have furthered science's understanding of carbon monoxide's natural characteristics and limitations by studying the gas in one of the world's best divers: the elephant seal.
Office of Naval Research, National Institutes of Health, National Science Foundation

Contact: Mario Aguilera
University of California - San Diego

Public Release: 14-May-2014
Science Translational Medicine
Can anti-depressants help prevent Alzheimer's disease?
A University of Pennsylvania researcher has discovered that the common selective serotonin reuptake inhibitor citalopram arrested the growth of amyloid beta, a peptide in the brain that clusters in plaques that are thought to trigger the development of Alzheimer's disease. Penn, in collaboration with investigators at Washington University, tested the drug's effects on the brain interstitial fluid in plaque-bearing mice and the cerebrospinal fluid of healthy human subjects.
National Institutes of Health

Contact: Lee-Ann Donegan
University of Pennsylvania School of Medicine

Public Release: 14-May-2014
Possible new plan of attack for opening and closing the blood-brain barrier
Researchers have identified the first gene that controls blood-brain barrier permeability through a little-studied phenomenon calledtranscytosis. The study, which was conducted in mice, offers a new way to devise strategies to open the blood-brain barrier for drug delivery or restore it in neurological disease.
National Institutes of Health, Alfred P. Sloan Foundation, Harvard Medical School

Contact: David Cameron
Harvard Medical School

Public Release: 14-May-2014
Science Translational Medicine
Inhibiting protein family helps mice survive radiation exposure, Stanford study finds
Tinkering with a molecular pathway that governs how intestinal cells respond to stress can help mice survive a normally fatal dose of abdominal radiation, according to a new study by researchers at the Stanford University School of Medicine. Because the technique is still partially effective up to 24 hours after exposure, the study suggests a possible treatment for people unintentionally exposed to large amounts of radiation, such as first responders at the Chernobyl nuclear disaster in 1986.
National Institutes of Health, Radiological Society of North America

Contact: Krista Conger
Stanford University Medical Center

Public Release: 13-May-2014
Environmental Science: Processes and Impacts
Clean air in Iowa
A new study from the University of Iowa reports Iowa's air quality falls within government guidelines for cleanliness, based on data gathered at five locations statewide. The study analyzed air quality and pollution sources in the state and is the first to compare air quality in urban versus rural areas. Results appear in the journal Environmental Science: Processes and Impacts.
National Institutes of Health.

Contact: Richard Lewis
University of Iowa

Public Release: 13-May-2014
Journal of Neuroscience
Human learning altered by electrical stimulation of dopamine neurons
Stimulation of a certain population of neurons within the brain can alter the learning process, according to a team of neuroscientists and neurosurgeons at the University of Pennsylvania. A report in the Journal of Neuroscience describes for the first time that human learning can be modified by stimulation of dopamine-containing neurons in a deep brain structure known as the substantia nigra.
National Institutes of Health

Contact: Kim Menard
University of Pennsylvania School of Medicine

Public Release: 13-May-2014
Protein Data Bank: 100,000 structures
Four wwPDB data centers in the US, UK and Japan support online access to three-dimensional structures of biological macromolecules that help researchers understand many facets of biomedicine, agriculture, and ecology, from protein synthesis to health. This public archive of experimentally determined protein and nucleic acid structures has reached a critical milestone of 100,000 structures, thanks to the efforts of structural biologists throughout the world.
National Science Foundation, National Institutes of Health, US Department of Energy

Contact: Christine Zardecki
Rutgers University

Public Release: 13-May-2014
TB lung infection causes changes in the diversity of gut bacteria in mice
Johns Hopkins researchers have found evidence in mice that a tuberculosis infection in the lungs triggers immune system signaling to the gut that temporarily decreases the diversity of bacteria in that part of the digestive tract.
Howard Hughes Medical Institute, NIH/National Institute of Allergy and Infectious Diseases

Contact: Stephanie Desmon
Johns Hopkins Medicine

Public Release: 13-May-2014
Journal of Neuroscience
Role of calcium in familial Alzheimer's disease clarified, pointing to new therapeutics
Mutations in two presenilin proteins associated with familial Alzheimer's disease disrupt the flow of calcium ions within neurons. Researchers have found that suppressing the hyperactivity of the calcium channels alleviated FAD-like symptoms in mice models of the disease. These new observations suggest that approaches based on modulating calcium signaling could be explored for new AD therapies.
NIH/National Institute of Mental Health

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 13-May-2014
Older, sicker men with early-stage prostate cancer do not benefit from aggressive treatment
Treating older men with early-stage prostate cancer who also have other serious underlying health problems with aggressive therapies such as surgery or radiation therapy does not help them live longer.
NIH/National Institutes of Diabetes and Digestive and Kidney Diseases, American Cancer Society

Contact: Kim Irwin
University of California - Los Angeles Health Sciences

Public Release: 13-May-2014
Nature Communications
Male infertility: It's all about the package
Infertility is generally thought of as a woman's problem. In fact, more than 3 million men across America also experience it. Today, researchers from Cold Spring Harbor Laboratory (CSHL) describe a key event during sperm development that is essential for male fertility. A team led by CSHL professor Alea Mills explains how a protein controls DNA packaging to protect a man's genetic information.
NIH/National Cancer Institute

Contact: Jaclyn Jansen
Cold Spring Harbor Laboratory

Public Release: 13-May-2014
Molecular Psychiatry
Researchers identify genetic marker linked to OCD
A group of researchers led by Johns Hopkins scientists say they have identified a genetic marker that may be associated with the development of obsessive-compulsive disorder, whose causes and mechanisms are among the least understood among mental illnesses.
NIH/National Institute of Mental Health

Contact: Stephanie Desmon
Johns Hopkins Medicine

Public Release: 13-May-2014
Tobacco Control
E-cigarettes and mental health
Researchers at University of California, San Diego School of Medicine report that people living with depression, anxiety or other mental health conditions are twice as likely to have tried e-cigarettes and three times as likely to be current users of the controversial battery-powered nicotine-delivery devices, as people without mental health disorders.
NIH/National Cancer Institute

Contact: Scott LaFee
University of California - San Diego

Public Release: 12-May-2014
Scientists slow brain tumor growth in mice
Much like using dimmer switches to brighten or darken rooms, biochemists have identified a protein that can be used to slow down or speed up the growth of brain tumors in mice.
Department of Defense, National Institutes of Health, Houston Endowment, Inc.

Contact: Robert Cahill
University of Texas Health Science Center at Houston

Public Release: 12-May-2014
UCSF: E-cigarettes expose people to more than harmless vapor, should be regulated
In a major scientific review of research on e-cigarettes, UC San Francisco scientists found that industry claims about the devices are unsupported by the evidence to date, including claims that e-cigarettes help smokers quit.
World Health Organization, University of California Tobacco Related Disease Research Program, NIH/National Cancer Institute, Food and Drug Administration

Contact: Elizabeth Fernandez
University of California - San Francisco

Public Release: 12-May-2014
Journal of Allergy and Clinical Immunology: In Practice
Birth by C-section, early antibiotic use put kids at risk for allergic esophagitis
Children delivered by Cesarean section and those given antibiotics during early infancy appear more prone to developing allergic inflammation of the esophagus -- the muscular tube that connects the mouth to the stomach -- according to results of a study by investigators from the Johns Hopkins Children's Center and Harvard Medical School.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Ekaterina Pesheva
Johns Hopkins Medicine

Public Release: 12-May-2014
Clinical Neurology and Neurosurgery
Henry Ford researchers identify genetic factors that may aid survival from brain cancer
A Henry Ford Hospital research team has identified specific genes that may lead to improved survival of glioblastoma, the most common and deadly form of cancerous brain tumor. The molecular data is expected to aid further research into genes that either help or impede the survival of patients diagnosed with the tumor, which can invade and rapidly grow in any part of the human brain.
Hermelin Brain Tumor Center, National Institutes of Health, Cancer Genome Atlas

Contact: Dwight Angell
Henry Ford Health System

Public Release: 12-May-2014
All in the rotation
Berkeley Lab researchers have shed new light on a type of molecular motor used to package the DNA of a number of viruses, including herpes and the adenoviruses. Their findings could help in the development of more effective drugs and inspire the design of new and improved synthetic biomotors.
National Institutes of Health, Howard Hughes Medical Institute

Contact: Lynn Yarris
DOE/Lawrence Berkeley National Laboratory

Public Release: 12-May-2014
Proceedings of the National Academy of Sciences
JAX researchers identify potential therapeutic target for wound-healing and cancer
A Jackson Laboratory research team led by Professor Lenny Shultz, Ph.D., reports that a protein involved in wound healing and tumor growth (an inactive rhomboid protease, iRhom2) could be a potential therapeutic target.
National Institutes of Health

Contact: Joyce Peterson
Jackson Laboratory

Showing releases 3176-3200 out of 3609.

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