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News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3201-3225 out of 3600.

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Public Release: 17-Apr-2014
Connecting sleep deficits among young fruit flies to disruption in mating later in life
Mom always said you need your sleep, and it turns out, she was right. According to a new study published in Science, the lack of sleep in young fruit flies profoundly diminishes their ability to do one thing they do really, really well -- make more flies.
National Institutes of Health, Howard Hughes Medical Institute

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 17-Apr-2014
Molecular Cell
Discovery could lead to novel therapies for Fragile X syndrome
Scientists studying the most common form of inherited mental disability -- a genetic disease called 'Fragile X syndrome' -- have uncovered new details about the cellular processes responsible for the condition that could lead to the development of therapies to restore some of the capabilities lost in affected individuals.
National Institutes of Health

Contact: Kim McDonald
University of California - San Diego

Public Release: 17-Apr-2014
PLOS Genetics
Deadly human pathogen Cryptococcus fully sequenced
A ten-year effort by an international team has sequenced the entire genome and all the RNA products of the most important pathogenic lineage of Cryptococcus neoformans, a strain called H99.These genetic instructions can give valuable insight into why a fungus responsible for a million cases of pneumonia and meningitis every year is so malleable and dangerous.
National Institutes of Health, French National Research Agency, National Health and Medical Research

Contact: Karl Bates
Duke University

Public Release: 17-Apr-2014
Neurons in the brain tune into different frequencies for different spatial memory tasks
Your brain transmits information about your current location and memories of past locations over the same neural pathways using different frequencies of a rhythmic electrical activity called gamma waves, report neuroscientists at The University of Texas at Austin. The research, published in the journal Neuron on April 17, may provide insight into the cognitive and memory disruptions seen in diseases such as schizophrenia and Alzheimer's, in which gamma waves are disturbed.
Klingenstein Fund, Alfred P. Sloan Foundation, NIH/National Institute of Mental Health

Contact: Marc Airhart
University of Texas at Austin

Public Release: 16-Apr-2014
Developmental Science
IU cognitive scientists use 'I spy' to show spoken language helps direct children's eyes
In a new study, Indiana U. cognitive scientists demonstrate that children spot objects more quickly when prompted by words than if they are only prompted by images. Spoken language taps into children's cognitive system, enhancing their ability to learn and to navigate cluttered environments. As such the study opens up new avenues for research into the way language might shape the course of developmental disabilities such as ADHD, difficulties with school, and other attention-related problems.
NIH/National Institute of Child Health and Development

Contact: Liz Rosdeitcher
Indiana University

Public Release: 16-Apr-2014
Biomedical Optics Express
New technique detects microscopic diabetes-related eye damage
Indiana University researchers have detected new early-warning signs of the potential loss of sight associated with diabetes. This discovery could have far-reaching implications for the diagnosis and treatment of diabetic retinopathy, potentially impacting the care of over 25 million Americans.
NIH/National Eye Institute

Contact: Tracy James
Indiana University

Public Release: 16-Apr-2014
High-level NIH grant goes to professor Nicolas Doucet of INRS
Professor Nicolas Doucet of the Centre INRS-Institut Armand-Frappier has just received a research grant from the National Institutes of Health in the amount of nearly $600,000. The five-year grant is to pursue cutting-edge research in the workings of tiny proteins called RNases and to explore their biomedical potential in the field of oncology as well as in inflammation and asthma.
National Institutes of Health

Contact: Gisèle Bolduc

Public Release: 16-Apr-2014
Researchers track down cause of eye mobility disorder
In a paper published in the April 16 print issue of the journal Neuron, University of Iowa researchers Bernd Fritzsch and Jeremy Duncan and their colleagues at Harvard Medical School, along with investigator and corresponding author Elizabeth Engle, describe how their studies on mutated mice mimic human mutations.
National Institutes of Health

Contact: Steve Kehoe
University of Iowa

Public Release: 16-Apr-2014
Mutant protein in muscle linked to neuromuscular disorder
Spinal and bulbar muscular atrophy (SBMA) is a rare inherited neuromuscular disorder characterized by slowly progressive muscle weakness and atrophy. In a new study published in the April 16, 2014, online issue of Neuron, a team of scientists at the University of California, San Diego School of Medicine say novel mouse studies indicate that mutant protein levels in muscle cells are fundamentally involved in SBMA, suggesting an alternative and promising new avenue of treatment.
National Institutes of Health, Muscular Dystrophy Association, Ludwig Institute

Contact: Scott LaFee
University of California - San Diego

Public Release: 16-Apr-2014
How kids' brain structures grow as memory develops
Our ability to store memories improves during childhood, associated with structural changes in the hippocampus and its connections with prefrontal and parietal cortices. New research from UC Davis is exploring how these brain regions develop at this crucial time. Eventually, that could give insights into disorders that typically emerge in the transition into and during adolescence and affect memory, such as schizophrenia and depression.
National Institutes of Health

Contact: Andy Fell
University of California - Davis

Public Release: 16-Apr-2014
Vanderbilt researchers discover how intestinal cells build nutrient-absorbing surface
The 'brush border' -- a densely packed array of finger-like projections called microvilli -- covers the surfaces of the cells that line our intestines. Vanderbilt University researchers have now discovered how intestinal cells build this specialized structure, which is critical for absorbing nutrients and defending against pathogens. The findings, published April 10 in Cell, reveal a role for adhesion molecules in brush border assembly and increase our understanding of intestinal pathologies associated with inherited and infectious diseases.
National Institutes of Health, American Heart Association, Vanderbilt Innovation and Discovery in Engineering And Science award

Contact: Leigh MacMillan
Vanderbilt University Medical Center

Public Release: 16-Apr-2014
Cancer drugs block dementia-linked brain inflammation, UCI study finds
A class of drugs developed to treat immune-related conditions and cancer -- including one currently in clinical trials for glioblastoma and other tumors -- eliminates neural inflammation associated with dementia-linked diseases and brain injuries, according to UC Irvine researchers.
NIH/National Institute of Neurological Disorders & Stroke

Contact: Tom Vasich
University of California - Irvine

Public Release: 16-Apr-2014
Scientists awarded $2 million to study improvements in anti-diabetic drug design
Scientists from the Florida campus of The Scripps Research Institute have been awarded $2.1 million from the National Institutes of Health to study the therapeutic potential of safer and more effective alternatives to the current crop of anti-diabetic drugs, which have been limited in their use due to side effects including bone loss and congestive heart failure.
National Institutes of Health

Contact: Eric Sauter
Scripps Research Institute

Public Release: 16-Apr-2014
Clinical Infectious Diseases
HIV+ women respond well to HPV vaccine
A three-nation clinical trial found that a vaccine can safely help the vast majority of HIV-positive women produce antibodies against the cancer-causing human papillomavirus, even if their immune system is weak and even if they've had some prior HPV exposure.
National Institutes of Health

Contact: David Orenstein
Brown University

Public Release: 16-Apr-2014
Genome Research
Research uncovers DNA looping damage tied to HPV cancer
Certain strains of human papillomavirus (HPV) are known to cause about five percent of all cancer cases, yet all the mechanisms aren't completely understood. Now, researchers, led by The Ohio State University's David Symer, M.D., Ph.D., have leveraged Ohio Supercomputer Center resources and whole-genome sequencing to identify a new way that HPV might spark cancer development -- by disrupting the human DNA sequence with repeating loops when HPV is inserted into host-cell DNA as it replicates.
NIH/National Cancer Institute Center for Cancer Research

Contact: Mr. Jamie Abel
Ohio Supercomputer Center

Public Release: 16-Apr-2014
Journal of Immunology
Progress in understanding immune response in severe schistosomiasis
Researchers at Tufts University have uncovered a mechanism that may help explain the severe forms of schistosomiasis, or snail fever, which is one of the most prevalent parasitic diseases in the world. The study in mice, published online this week in The Journal of Immunology, may also offer targets for intervention and amelioration of the disease.
NIH/National Institute of Allergy and Infectious Diseases, NIH/Office of the Director, Canadian Institutes of Health Research, National Research Foundation of Korea-Global Research Network

Contact: Siobhan Gallagher
Tufts University, Health Sciences Campus

Public Release: 16-Apr-2014
Researchers see hospitalization records as additional tool
By comparing hospitalization records from Massachusetts hospitals with data reported to local boards of health found a more accurate way to monitor how well communities track disease outbreaks.
National Institutes of Health

Contact: Alex Reid
Tufts University

Public Release: 16-Apr-2014
Low vitamin D may not be a culprit in menopause symptoms
A new study from the Women's Health Initiative shows no significant connection between vitamin D levels and menopause symptoms. The study was published online today in Menopause, the journal of The North American Menopause Society.
NIH/National Heart, Lung, and Blood Institute

Contact: Jennifer Bahun
The North American Menopause Society (NAMS)

Public Release: 16-Apr-2014
Scientists re-define what's healthy in newest analysis for Human Microbiome Project
As scientists catalog the trillions of bacteria found in the human body, a new look by the University of Michigan shows wide variation in the types of bacteria found in healthy people.
National Institutes of Health

Contact: Shantell M. Kirkendoll
University of Michigan Health System

Public Release: 16-Apr-2014
Research may help doctors predict who gets long-term complications from Lyme disease
A team of scientists led by Johns Hopkins and Stanford University researchers has laid the groundwork for understanding how variations in immune responses to Lyme disease can contribute to the many different outcomes of this bacterial infection seen in individual patients. A report on the work appears online April 16 in PLOS One.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Stephanie Desmon
Johns Hopkins Medicine

Public Release: 16-Apr-2014
Science Translational Medicine
Researchers develop a new drug to combat the measles
A novel antiviral drug may protect people infected with the measles from getting sick and prevent them from spreading the virus to others, an international team of researchers says.
NIH/National Institute of Allergy and Infectious Diseases

Contact: LaTina Emerson
Georgia State University

Public Release: 16-Apr-2014
Journal of Adolescent Health
Masculine boys, feminine girls more likely to engage in cancer risk behaviors
The most 'feminine' girls and 'masculine' boys -- are more likely than their peers to engage in behaviors that pose cancer risks, according to a new study led by Harvard School of Public Health researchers. The most feminine teenage girls use tanning beds more frequently and are more likely to be physically inactive, while the most masculine teenage boys are more likely to chew tobacco and smoke cigars compared with gender-nonconforming peers.
National Institutes of Health, Maternal and Child Health Bureau, Health Resources and Services Administration, Leadership Education in Adolescent Health Project

Contact: Marge Dwyer
Harvard School of Public Health

Public Release: 15-Apr-2014
Annals of Internal Medicine
Pre-diabetes and diabetes nearly double over the past 2 decades
Cases of diabetes and pre-diabetes in the United States have nearly doubled since 1988, suggests new research from the Johns Hopkins Bloomberg School of Public Health, with obesity apparently to blame for the surge. The researchers also found that the burden of the disease has not hit all groups equally, with alarming increases in diabetes in blacks, Hispanics and the elderly.
National Institutes of Health

Contact: Susan Sperry
Johns Hopkins University Bloomberg School of Public Health

Public Release: 15-Apr-2014
Study: SSRI use during pregnancy associated with autism and developmental delays in boys
In a study of nearly 1,000 mother-child pairs, researchers from the Bloomberg School of Public health found that prenatal exposure to selective serotonin reuptake inhibitors (SSRIs), a frequently prescribed treatment for depression, anxiety and other disorders, was associated with autism spectrum disorder and developmental delays in boys.
NIH/National Institute of Environmental Health Sciences

Contact: Susan Sperry
Johns Hopkins University Bloomberg School of Public Health

Public Release: 15-Apr-2014
Nature Chemical Biology
Potent, puzzling and (now less) toxic: Team discovers how antifungal drug works
Scientists have solved a decades-old medical mystery -- and in the process have found a potentially less toxic way to fight invasive fungal infections, which kill about 1.5 million people a year. The researchers say they now understand the mechanism of action of amphotericin, an antifungal drug that has been in use for more than 50 years -- even though it is nearly as toxic to human cells as it is to the microbes it attacks.
National Institutes of Health, Howard Hughes Medical Institute

Contact: Diana Yates
University of Illinois at Urbana-Champaign

Showing releases 3201-3225 out of 3600.

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