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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3201-3225 out of 3647.

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Public Release: 5-Jun-2014
Cell Reports
University of Toronto biologists pave the way for improved epilepsy treatments
University of Toronto biologists leading an investigation into the cells that regulate proper brain function, have identified and located the key players whose actions contribute to afflictions such as epilepsy and schizophrenia. The discovery is a major step toward developing improved treatments for these and other neurological disorders.
Canadian Institutes of Health Research, National Institutes of Health, Academy of Finland

Contact: Sean Bettam
University of Toronto

Public Release: 5-Jun-2014
The connection between oxygen and diabetes
Researchers at the University of California, San Diego School of Medicine have, for the first time, described the sequence of early cellular responses to a high-fat diet, one that can result in obesity-induced insulin resistance and diabetes. The findings also suggest potential molecular targets for preventing or reversing the process.
National Institutes of Health, American Diabetes Association

Contact: Scott LaFee
University of California - San Diego

Public Release: 5-Jun-2014
SLEEP 2014
Couples sleep in sync when the wife is satisfied with their marriage
Couples are more likely to sleep in sync when the wife is more satisfied with their marriage. Results show that overall synchrony in sleep-wake schedules among couples was high, as those who slept in the same bed were awake or asleep at the same time about 75 percent of the time. When the wife reported higher marital satisfaction, the percent of time the couple was awake or asleep at the same time was greater.
NIH/National Heart, Lung, and Blood Institute

Contact: Lynn Celmer
630-737-9700 x9364
American Academy of Sleep Medicine

Public Release: 5-Jun-2014
Cell Stem Cell
Stem cells hold keys to body's plan
Case Western Reserve researchers have discovered landmarks within pluripotent stem cells that guide how they develop to serve different purposes within the body. This breakthrough offers promise that scientists eventually will be able to direct stem cells in ways that prevent disease or repair damage from injury or illness. The study and its results appear in the June 5 edition of the journal Cell Stem Cell.
National Institutes of Health, New York Stem Cell Foundation, Mount Sinai Health Care Foundation, Case Comprehensive Cancer Center, Case Western Reserve University

Contact: Jeannette Spalding
Case Western Reserve University

Public Release: 5-Jun-2014
Endocrine Society honors 2014 Early Investigators, FLARE Internship Award winners
The Endocrine Society is pleased to announce the recipients of the 2014 Early Investigators Awards and the Future Leaders Advancing Research in Endocrinology (FLARE) Internship Awards.
Endocrine Society, NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Jenni Glenn Gingery
The Endocrine Society

Public Release: 5-Jun-2014
The EMBO Journal
Scripps Florida scientists unravel the molecular secret of short, intense workouts
The benefits of short, intense workouts have been extolled by researchers and exercise fans as a metabolic panacea capable of providing greater overall fitness, better blood sugar control and weight reduction -- all of it in periods as short as seven minutes a few times a week. In a new study, scientists from the Florida campus of The Scripps Research Institute confirm something is molecularly unique about intense exercise: the activation of a single protein.
National Institutes of Health, State of Florida

Contact: Eric Sauter
Scripps Research Institute

Public Release: 5-Jun-2014
Breast Cancer Research
Can mice mimic human breast cancer? MSU study says 'yes'
Eran Andrechek, a physiology professor in the College of Human Medicine at Michigan State University, has discovered that many of the various models used in breast cancer research can replicate several characteristics of the human disease, especially at the gene level.
National Institutes of Health, Susan G. Komen Foundation

Contact: Sarina Gleason
Michigan State University

Public Release: 5-Jun-2014
Sleep after learning strengthens connections between brain cells and enhances memory
Researchers at NYU Langone Medical Center show for the first time that sleep after learning encourages the growth of dendritic spines, the tiny protrusions from brain cells that connect to other brain cells and facilitate the passage of information across synapses, the junctions at which brain cells meet.
National Institutes of Health, Whitehall Foundation

Contact: Jim Mandler
NYU Langone Medical Center / New York University School of Medicine

Public Release: 5-Jun-2014
Vanderbilt scientists discover that chemical element bromine is essential to human life
Twenty-seven chemical elements are considered to be essential for human life. Now there is a 28th -- bromine. In a paper published Thursday by the journal Cell, Vanderbilt University researchers establish for the first time that bromine, among the 92 naturally-occurring chemical elements in the universe, is the 28th element essential for tissue development in all animals, from primitive sea creatures to humans.
National Institutes of Health

Contact: Craig Boerner
Vanderbilt University Medical Center

Public Release: 5-Jun-2014
Unmasking viral invaders
Using a technological platform commonly used in physics and chemistry called mass spectrometry, researchers describe the dynamics of a viral infection over a three-day course, discovering ways the pathogen evades the immune system and how certain viral proteins target and destroy human proteins that defend against infection.
Wellcome Trust Fellowship, National Institutes of Health

Contact: David Cameron
Harvard Medical School

Public Release: 5-Jun-2014
Research helps clarify how obesity leads to type 2 diabetes, cancer
In a study published online June 5 in the journal Cell, a researcher at The University of Texas at Dallas and colleagues at the University of California, San Diego found that a protein called HIF-1 alpha plays a key role in the development of insulin resistance and type 2 diabetes in obese mice. The findings may also shed light on the connection between obesity and cancer.
National Institutes of Health, American Diabetes Association

Contact: Amanda Siegfried
University of Texas at Dallas

Public Release: 5-Jun-2014
Molecular Cell
New method reveals single protein interaction key to embryonic stem cell differentiation
Researchers from the University of Chicago have pioneered a new technique to simplify the study of protein networks and identify the importance of individual protein interactions. By designing synthetic proteins that can only interact with a pre-determined partner, and introducing them into cells, the team revealed a key interaction that regulates the ability of embryonic stem cells to change into other cell types.
National Institutes of Health

Contact: Kevin Jiang
University of Chicago Medical Center

Public Release: 5-Jun-2014
Scientists generate long-sought molecular map of critical genetic machinery
A team led by researchers at The Scripps Research Institute has used advanced electron microscopy techniques to determine the first accurate structural map of Mediator, one of the largest and most complex 'molecular machines' in cells. The mapping of its structure -- which includes more than two dozen unique protein subunits--represents a significant advance in basic cell biology and should shed light on medical conditions involving Mediator's dysfunction, from cancer to inherited developmental disorders.
National Institutes of Health, Helen Nelson Medical Research Fund

Contact: Mika Ono
Scripps Research Institute

Public Release: 5-Jun-2014
Immune system molecules may promote weight loss, UCSF study finds
The calorie-burning triggered by cold temperatures can be achieved biochemically -- without the chill -- raising hopes for a weight-loss strategy focused on the immune system rather than the brain, according to a new study by UC San Francisco researchers.
National Institutes of Health, American Heart Association

Contact: Jeffrey Norris
University of California - San Francisco

Public Release: 5-Jun-2014
Environmental Health Perspectives
New evidence links air pollution to autism, schizophrenia
A new study describes how exposure to air pollution early in life produces harmful changes in the brains of mice, including an enlargement of part of the brain that is seen in humans who have autism and schizophrenia. The mice performed poorly in tests of short-term memory, learning ability, and impulsivity. Study authors say the findings are very suggestive that air pollution may play a role in autism, as well as in other neurodevelopmental disorders.
NIH/National Institute of Environmental Health Sciences

Contact: Christopher DiFrancesco
University of Rochester Medical Center

Public Release: 5-Jun-2014
Cell Stem Cell
Fasting triggers stem cell regeneration of damaged, old immune system
In the first evidence of a natural intervention triggering stem cell-based regeneration of an organ or system, a study in the June 5 issue of the Cell Press journal Cell Stem Cell shows that cycles of prolonged fasting not only protect against immune system damage -- a major side effect of chemotherapy -- but also induce immune system regeneration, shifting stem cells from a dormant state to a state of self-renewal.
NIH/National Institute on Aging

Contact: Suzanne Wu
University of Southern California

Public Release: 5-Jun-2014
PLOS Genetics
Silent mutations speak up
Returning to research of years ago, U biologists developed an assay to test effects of all possible silent mutations on protein translation. One-third of silent mutations caused a slow down in speed of protein translation, in some cases by as much as five-fold.
National Institutes of Health

Contact: Kelly T. Hughes
University of Utah

Public Release: 5-Jun-2014
Cell Reports
McLean Hospital researchers see promise in transplanted fetal stem cells for Parkinson's
Researchers at Harvard-affiliated McLean Hospital have found that fetal dopamine cells transplanted into the brains of patients with Parkinson's disease were able to remain healthy and functional for up to 14 years, a finding that could lead to new and better therapies for the illness.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Jenna Brown
McLean Hospital

Public Release: 4-Jun-2014
Journal of Neuroscience
UO researchers use rhythmic brain activity to track memories in progress
Using EEG electrodes attached to the scalps of 25 student subjects, University of Oregon researchers have tapped the rhythm of memories as they occur in near real time in the human brain.
NIH/National Institute of Mental Health

Contact: Jim Barlow
University of Oregon

Public Release: 4-Jun-2014
Researching how residential environment impacts preterm delivery in African-Americans
High levels of racial disparities in preterm delivery exist, with African-Americans having higher rates than non-Hispanic whites. Since traditional risk factors do not fully account for this disparity, other explanations are needed and researchers at Wayne State University are teaming up to find answers.
National Institutes of Health

Contact: Julie O'Connor
Wayne State University - Office of the Vice President for Research

Public Release: 4-Jun-2014
A new approach to Alzheimer's disease research
As part of its ongoing research to better understand the complexities of the human brain, the Allen Institute for Brain Science is embarking on the first effort to map connectivity patterns across the whole brain in mouse models of Alzheimer's disease, through its recent award of a $3.4 million grant over five years from the National Institute on Aging of the National Institutes of Health.
National Institutes of Health

Contact: Steven Cooper
Edelman Public Relations

Public Release: 4-Jun-2014
Proceedings of the National Academy of Sciences
Hemorrhagic fevers can be caused by body's antiviral interferon response
Virologists and immunologists at The Scripps Research Institute have found a major clue to the mystery of 'hemorrhagic fever' syndromes. The team showed that Interferon Type I immune proteins are key drivers of a viral syndrome in mice that closely mimics human hemorrhagic fevers.
National Institutes of Health

Contact: Mika Ono
Scripps Research Institute

Public Release: 4-Jun-2014
Medical Physics
New diagnostic imaging techniques deemed safe in simulations
Gamma and neutron imaging offer possible improvements over existing techniques such as X-ray or CT, but their safety is not yet fully understood. Using computer simulations, imaging the liver and breast with gamma or neutron radiation was found to be safe, delivering levels of radiation on par with conventional medical imaging, according to researchers at Duke Medicine.
National Institutes of Health

Contact: Rachel Harrison
Duke University Medical Center

Public Release: 4-Jun-2014
Dad's alcohol consumption could influence sons' drinking, Pitt study finds
Even before conception, a son's vulnerability for alcohol use disorders could be shaped by a father who chronically drinks to excess, according to a study from the University of Pittsburgh School of Medicine. The findings in PLOS ONE show male mice that were chronically exposed to alcohol before breeding had male offspring that were less likely to consume alcohol and more sensitive to its effects, providing new insight into inheritance and development of drinking behaviors.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Anita Srikameswaran
University of Pittsburgh Schools of the Health Sciences

Public Release: 4-Jun-2014
Journal of the Academy of Nutrition and Dietetics
Saturated fat intake may influence a person's expression of genetic obesity risk
In a new study, researchers from the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University associate a person's genetic risk for obesity with Body Mass Index, and show that saturated fat intake may influence the expression of a person's genetic obesity risk.
National Institutes of Health

Contact: Andrea Grossman
Tufts University, Health Sciences Campus

Showing releases 3201-3225 out of 3647.

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