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Key: Meeting M      Journal J      Funder F

Showing releases 3201-3225 out of 3696.

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Public Release: 22-Jan-2015
Study projects unprecedented loss of corals in Great Barrier Reef due to warming
The coverage of living corals on Australia's Great Barrier Reef could decline to less than 10 percent if ocean warming continues, according to a new study that explores the short- and long-term consequences of environmental changes to the reef.
NIH/National Institute for Mathematical and Biological Synthesis

Contact: Catherine Crawley
National Institute for Mathematical and Biological Synthesis (NIMBioS)

Public Release: 22-Jan-2015
PLOS Medicine
Risk of HIV infection in studies of African women using hormonal contraceptives
Use of the injectable progestin contraceptive depot-medroxyprogesterone acetate is linked to an increased risk for HIV infection, according to an article published by Charles Morrison of FHI 360 and colleagues in this week's PLOS Medicine. The researchers did not find a significantly increased risk for HIV infection in women who used a different injectable progestin, norethisterone enanthate, nor in those who used combined oral contraceptives.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bill and Melinda Gates Foundation

Contact: Maya Sandler

Public Release: 22-Jan-2015
Molecular Cell
Penn study uncovers secrets of a clump-dissolving protein
Workhorse molecules called heat-shock proteins contribute to refolding proteins that were once misfolded and clumped, causing such disorders as Parkinson's disease, amyotrophic lateral sclerosis, and Alzheimer's disease. Researchers are developing ways to 'reprogram' one such protein -- a yeast protein called Hsp104 -- to improve its therapeutic properties.
NIH/National Institute of General Medical Sciences, NIH/National Institute of Neurological Disorders and Stroke, National Institutes of Health Common Fund, Ellison Medical Foundation New Scholar in Aging Award, Target ALS, Muscular Dystrophy Association

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 22-Jan-2015
Molecular Cell
Using viruses to find the cellular Achilles heel
Back-to-back studies from researchers at the Gladstone Institutes have exposed new battle tactics employed by two deadly viruses: hepatitis C and the Kaposi's sarcoma-associated herpesvirus. Protein interaction maps -- interactomes -- of where the viruses come into contact with the host during the course of infection uncovered a common set of cellular proteins that are attacked by various infections and may serve as viable new targets for anti-viral treatments.
National Institutes of Health, Defense Advanced Research Projects Agency, California HIV/AIDS Research Program, Gladstone Institutes, University of California San Francisco Liver Center

Contact: Dana Smith
Gladstone Institutes

Public Release: 22-Jan-2015
American Journal of Transplantation
New machine-perfusion organ preservation system keeps livers healthier for transplant
A new preservation system that pumps cooled, oxygen-rich fluid into donor livers not only keeps the organs in excellent condition for as long as nine hours before transplantation, but also leads to dramatically better liver function and increases survival of recipients, according to animal studies conducted by researchers at the University of Pittsburgh School of Medicine and the McGowan Institute for Regenerative Medicine. The system could be tested with transplant patients at UPMC next year.
National Institutes of Health, Mr. and Mrs. Garcia de Souza

Contact: Anita Srikameswaran
University of Pittsburgh Schools of the Health Sciences

Public Release: 22-Jan-2015
Enzymes believed to promote cancer actually suppress tumors
Upending decades-old dogma, a team of scientists at the University of California, San Diego School of Medicine say enzymes long categorized as promoting cancer are, in fact, tumor suppressors and that current clinical efforts to develop inhibitor-based drugs should instead focus on restoring the enzymes' activities.
National Institutes of Health, James S. McDonnell Foundation, UCSD/Graduate Training Program in Cellular and Molecular Pharmacology, National Science Foundation/Graduate Research Fellowship, Cancer Research UK

Contact: Scott LaFee
University of California - San Diego

Public Release: 22-Jan-2015
Nature Communications
Cell's recycling team helps sound alarm on pathogens
Autophagy recycles materials in the cell and is also an efficient method of eliminating viruses, bacteria, and parasites. However, for fungal invaders, Duke researchers have found that the cleanup crew takes a less straightforward approach. Rather than killing fungal invaders directly, autophagy is used to chew up a molecule that would otherwise hold back the immune response. It's sort of like breaking the glass on an alarm to allow the button to be pushed.
National Institutes of Health, Uehara Memorial Foundation

Contact: Karl Bates
Duke University

Public Release: 22-Jan-2015
Cell Host & Microbe
Immune system promotes digestive health by fostering community of 'good' bacteria
1.4 million Americans suffer from uncomfortable abdominal cramping and diarrhea that come with inflammatory bowel disease. The condition is associated with an imbalance among the thousands of species of 'good' bacteria that inhabit the gut. A University of Utah study published on Jan. 22 in Cell Host and Microbe demonstrates that a component of the immune system, MyD88, coordinates a host immune response that promotes a healthy colony of good bacteria, and digestive health.
National Institutes of Health, American Cancer Society, Edward Mallinckrodt Jr. Foundation, Sidney Kimmel Foundation, Pew Scholars Program, Packard Fellowship in Science and Engineering

Contact: Julie Kiefer
University of Utah Health Sciences

Public Release: 22-Jan-2015
Reducing Myc gene activity extends healthy lifespan in mice
Mice with one rather than the normal two copies of the gene Myc (also found in humans) lived 15 percent longer and had considerably healthier lives than normal mice, according to a new Brown University-led study in Cell.
National Institutes of Health, Ellison Medical Foundation, Glenn Award

Contact: David Orenstein
Brown University

Public Release: 21-Jan-2015
Nature Communications
Scientists find gene vital to central nervous system development
Scientists have identified a gene that helps regulate how well nerves of the central nervous system are insulated, researchers at Washington University School of Medicine in St. Louis report.
National Institutes of Health, Edward J. Mallinckrodt Foundation, William Randolph Hearst Fund, Leonard and Isabelle Goldenson Research Fellowship, Cerebral Palsy International Research Foundation

Contact: Julia Evangelou Strait
Washington University School of Medicine

Public Release: 21-Jan-2015
BMC Evolutionary Biology
Most endangered chimpanzees have complex evolutionary past, perilous future
Complementary analyses of population genetics, geographical distribution and habitat use paint a new picture of the evolutionary past and potentially bleak future of the Nigeria-Cameroon Chimpanzee (Pan troglodytes ellioti), already the most endangered chimp subspecies. There are unexpectedly two distinct populations of the Nigeria-Cameroon chimpanzee which have closer ties to their habitats than previously anticipated. And climate change could cause them significant and rapid harm.
National Science Foundation, National Institutes of Health, National Geographic, Offield Family Foundation, USFWS Great Apes Conservation Fund, Arcus Foundation

Contact: Rachel Ewing
Drexel University

Public Release: 21-Jan-2015
Biological Psychiatry
Scientists move closer to a personalized treatment solution for intellectual disability
Scientists from the Florida campus of The Scripps Research Institute have produced an approach that protects animal models against a type of genetic disruption that causes intellectual disability, including serious memory impairments and altered anxiety levels.
NIH/National Institute for Neurological Disorders and Stroke, NIH/National Institute for Mental Health, NIH/National Institute for Drug Abuse, NIH/National Institute on Deafness and Other Communication Disorders, and others

Contact: Eric Sauter
Scripps Research Institute

Public Release: 21-Jan-2015
Science Translational Medicine
New drug compounds show promise against endometriosis
Two new drug compounds -- one of which has already proven useful in a mouse model of multiple sclerosis -- appear to be effective in treating endometriosis, a disorder that, like MS, is driven by estrogen and inflammation, scientists report in Science Translational Medicine.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health

Contact: Diana Yates
University of Illinois at Urbana-Champaign

Public Release: 21-Jan-2015
Molecular & Cellular Proteomics
Case Western Reserve scientists identify proteins likely to trigger psoriasis
Case Western Reserve scientists have taken a huge leap toward identifying root causes of psoriasis, an inflammatory skin condition affecting 125 million people around the world. Of the roughly 50,000 proteins in the human body, researchers have zeroed in on four that appear most likely to contribute this chronic disease. The findings, published this month in Molecular & Cellular Proteomics, dramatically advance efforts to understand how psoriasis develops -- and, in turn, how to stop it.
National Psoriasis Foundation, The Lozick Discovery Grant, National Psoriasis Foundation, Babcock Foundation Endowment, National Institutes of Health

Contact: Jeannette Spalding
Case Western Reserve University

Public Release: 21-Jan-2015
Only about half of teenage girls receive HPV vaccine at the CDC's recommended age
A virus is responsible for most cases of cervical cancer but a new study by University of Texas Medical Branch at Galveston indicates that only about half of the girls receive the vaccine at the recommended age. The Human papilloma virus vaccine protects against 70 percent of cervical cancers. The CDC has recommended that girls get the vaccine when they are 11-12, because it is most effective when it is given before girls become sexually active.
National Institutes of Health

Contact: Donna Ramirez
University of Texas Medical Branch at Galveston

Public Release: 21-Jan-2015
LSU Health New Orleans identifies toxic Ebola protein fragment
William Gallaher, PhD, Emeritus Professor of Microbiology, Immunology and Parasitology at Louisiana State University Health New Orleans School of Medicine, has discovered a fragment of an Ebola virus protein that is toxic to cells and may contribute to infection and illness. The findings were published online Jan. 20, 2015, in the open access journal, Viruses.
National Institutes of Health

Contact: Leslie Capo
Louisiana State University Health Sciences Center

Public Release: 21-Jan-2015
USC study finds blood vessels in older brains break down, possibly leading to Alzheimer's
Researchers at Keck Medicine of USC used high-resolution imaging of the living human brain to show for the first time that the brain's protective blood barrier becomes leaky with age, starting at the hippocampus, a critical learning and memory center that is damaged by Alzheimer's disease.
National Institutes of Health, the Zilkha Senior Scholar program, L. K. Whittier Foundation

Contact: Alison Trinidad
University of Southern California - Health Sciences

Public Release: 21-Jan-2015
New England Journal of Medicine
Deaths of extremely premature infants decrease, fewer dying of breathing complications
In a large, national study of extremely premature infants, researchers found that death rates decreased from 2000 to 2011. An analysis of specific causes found that deaths attributed to immaturity or pulmonary causes and complicated by infection or central nervous system injury all decreased; however, deaths attributed to necrotizing enterocolitis increased.
NIH/National Institute of Child Health and Human Development, NIH/National Center for Advancing Translational Sciences, Atlanta Clinical and Translational Science Institute, Emory-Children's Center for Clinical and Translational Research

Contact: Holly Korschun
Emory Health Sciences

Public Release: 21-Jan-2015
American Journal of Clinical Nutrition
Fatty acids in fish may shield brain from mercury damage
New findings from research in the Seychelles provide further evidence that the benefits of fish consumption on prenatal development may offset the risks associated with mercury exposure. In fact, the new study, which appears today in the American Journal of Clinical Nutrition, suggests that the nutrients found in fish have properties that protect the brain from the potential toxic effects of the chemical.
NIH/National Institute of Environmental Health Sciences, Government of Seychelles

Contact: Mark Michaud
University of Rochester Medical Center

Public Release: 21-Jan-2015
NYU researchers reveal how the mundane can be meaningful -- and remembered
It's not surprising that our memories of highly emotional events are quite strong. But can these events change our memories of the past? New York University researchers report that emotional learning can lead to the strengthening of older memories.
National Institutes of Health, NIH/National Institute of Mental Health

Contact: James Devitt
New York University

Public Release: 20-Jan-2015
UChicago projects capture drug-development grants for sleep apnea, asthma research
Research teams based at the University of Chicago have received prestigious grants from the National Institutes of Health to develop novel medications to treat sleep apnea and asthma.
National Institutes of Health

Contact: John Easton
University of Chicago Medical Center

Public Release: 20-Jan-2015
Nature Genetics
Harnessing data from Nature's great evolutionary experiment
Researchers at CSHL have developed a new computational method to identify which letters in the human genome are functionally important. Their computer program, called fitCons, harnesses the power of evolution, comparing changes in DNA letters across not just related species, but also between multiple individuals in a single species. The results provide a surprising picture of just how little of our genome has been 'conserved' by Nature.
National Institutes of Health, David and Lucile Packard Fellowship, Cornell Center for Comparative and Population Genomics

Contact: Jaclyn Jansen
Cold Spring Harbor Laboratory

Public Release: 20-Jan-2015
Patient Education and Counseling
Education aids understanding, reduces stigma of facial paralysis, OSU study shows
A little bit of sensitivity training can help people form better first impressions of those with facial paralysis, reducing prejudices against people with a visible but often unrecognizable disability, new research from Oregon State University indicates.
National Institutes of Health

Contact: Kathleen Bogart
Oregon State University

Public Release: 20-Jan-2015
Advanced Materials
One nanoparticle, 6 types of medical imaging
Using two biocompatible parts, University at Buffalo researchers and their colleagues have designed a nanoparticle that can be detected by six medical imaging techniques: computed tomography scanning; positron emission tomography scanning; photoacoustic imaging; fluorescence imaging; upconversion imaging; and Cerenkov luminescence imaging.
National Science Foundation, National Institutes of Health, American Cancer Society, Natural Science Foundation of China, Program for the Basic Research Excellent Talents in Harbin Institute of Technology, and others

Contact: Charlotte Hsu
University at Buffalo

Public Release: 20-Jan-2015
Proceedings of the National Academy of Sciences
Scientists identify important mechanism involved in production of mosquito eggs
Female mosquitoes rely on a blood-meal as a source of nutrients required for reproduction. If the mechanisms that govern mosquitoes' egg production are better understood, novel approaches to controlling the reproduction and population of mosquitoes can be devised. A team of UC Riverside scientists has made a research breakthrough in understanding, at the molecular level, one such mechanism related to the mosquito reproductive process. This mechanism includes small regulatory RNA molecules known as microRNAs.
National Institutes of Health

Contact: Iqbal Pittalwala
University of California - Riverside

Showing releases 3201-3225 out of 3696.

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