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News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3201-3225 out of 3510.

<< < 124 | 125 | 126 | 127 | 128 | 129 | 130 | 131 | 132 | 133 > >>

Public Release: 21-Nov-2013
Cincinnati Children's researchers develop first molecular test to diagnose eosinophilic esophagitis
Researchers at Cincinnati Children's Hospital Medical Center have developed the first molecular test to diagnose eosinophilic esophagitis (EoE), a chronic upper gastrointestinal disorder. The incidence of EoE has skyrocketed since it was first characterized two decades ago.
National Institutes of Health

Contact: Jim Feuer
Cincinnati Children's Hospital Medical Center

Public Release: 21-Nov-2013
AIDS Patient Care and STDs
High HIV knowledge and risky sexual behavior not associated with HIV testing in young adolescents
New research from Montefiore Medical Center and Albert Einstein College of Medicine has found that teens most likely to be tested for HIV had strong partner communication about HIV and were in committed relationships. Having high knowledge about HIV and engaging in risky sexual activity did not increase testing. The study of nearly 1,000 Bronx, NY teens was published in the November issue of AIDS Patient Care and STDs.
NIH/National Institute of Mental Health, NIH/National Institute on Drug Abuse

Contact: Deirdre Branley
Albert Einstein College of Medicine

Public Release: 21-Nov-2013
Stress and isolation take toll on those under 50 with HIV; older people fare better
Case Western Reserve University researchers were surprised to learn that people younger than 50 years old with HIV feel more isolated and stressed than older people with the disease. They expected their study to reveal just the opposite.
NIH/National Institute for Allergy and Infectious Disease

Contact: Susan Griffith
Case Western Reserve University

Public Release: 21-Nov-2013
Advanced Healthcare Materials
Ultrasound, nanoparticles may help diabetics avoid the needle
A new nanotechnology-based technique for regulating blood sugar in diabetics may give patients the ability to release insulin painlessly using a small ultrasound device, allowing them to go days between injections -- rather than using needles to give themselves multiple insulin injections each day.
National Institutes of Health

Contact: Matt Shipman
North Carolina State University

Public Release: 21-Nov-2013
2 human proteins found to affect how 'jumping gene' gets around
Using a new method to catch elusive "jumping genes" in the act, researchers have found two human proteins that are used by one type of DNA to replicate itself and move from place to place. The discovery, described in the Nov. 21 issue of Cell, breaks new ground in understanding the arms race between a jumping gene and cells working to limit the risk posed by such volatile bits of DNA.
NIH/National Institute of General Medical Sciences

Contact: Shawna Williams
Johns Hopkins Medicine

Public Release: 21-Nov-2013
Molecular Cell
Targets of anticancer drugs have broader functions than what their name suggests
Drugs that inhibit the activity of enzymes called histone deacetylases (HDACs) are being widely developed for treating cancer and other diseases, with two already on the market. Researchers show that a major HDAC still functions in mice even when its enzyme activity is abolished, suggesting that the beneficial effects of HDAC inhibitors may not actually be through inhibiting HDAC activity, and thus warranting the reassessment of the molecular targets of this class of drugs.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 21-Nov-2013
Cell Metabolism
New link between obesity and diabetes found
A single overactive enzyme worsens the two core defects of diabetes -- impaired insulin sensitivity and overproduction of glucose -- suggesting that a drug targeting the enzyme could help correct both at once, according to mouse studies done by researchers at Columbia University Medical Center. The findings were published today in the online edition of Cell Metabolism.
National Institutes of Health, American Heart Association, New York Obesity Research Center, Foundation for Research Support of the State of São Paulo, German Center for Cardiovascular Research, German Ministry of Education

Contact: Karin Eskenazi
Columbia University Medical Center

Public Release: 21-Nov-2013
UCLA first to map autism-risk genes by function
UCLA neuroscientists are the first to map groups of autism-risk genes by function, and uncover how mutations disrupt fetal brain development. Their findings prioritize genetic targets for future research and shed light on autism's molecular origins.
Simons Foundation, NIH/National Institute of Mental Health

Contact: Elaine Schmidt
University of California - Los Angeles Health Sciences

Public Release: 21-Nov-2013
Genetic defect keeps verbal cues from hitting the mark
A genetic defect that profoundly affects speech in humans also disrupts the ability of songbirds to sing effective courtship tunes. This defect in a gene called FoxP2 renders the brain circuitry insensitive to feel-good chemicals that serve as a reward for speaking the correct syllable or hitting the right note, a recent study shows.
National Institutes of Health

Contact: Karl Leif Bates
Duke University

Public Release: 21-Nov-2013
Study of fluke parasites identifies drug resistance mutations; raises hope for new therapies
An international group of scientists lead by Tim Anderson Ph.D., at the Texas Biomedical Research Institute and Philip LoVerde Ph.D., at the University of Texas Health Science Center at San Antonio has identified the mutations that result in drug resistance in a parasite infecting 187 million people in South America, Africa and Asia. The new finding allows detailed understanding of the drugs' mechanism of action and raises prospects of improved therapies.
National Institutes of Health, World Health Organization, Wellcome Trust

Contact: Tim Anderson
Texas Biomedical Research Institute

Public Release: 21-Nov-2013
2 Y genes can replace the entire Y chromosome for assisted reproduction in mice
Live mouse offspring can be generated with assisted reproduction using germ cells from males with the Y chromosome contribution limited to only two genes: the testis determinant factor Sry and the spermatogonial proliferation factor Eif2s3y.
National Institutes of Health, Hawaii Community Foundation

Contact: Monika A. Ward
University of Hawaii at Manoa

Public Release: 20-Nov-2013
Proceedings of the National Academy of Sciences
Scripps oceanography researchers engineer breakthrough for biofuel production
Researchers at Scripps Institution of Oceanography at UC San Diego have developed a method for greatly enhancing biofuel production in tiny marine algae. As reported in this week's online edition of the Proceedings of the National Academy of Sciences, Scripps graduate student Emily Trentacoste led the development of a method to genetically engineer a key growth component in biofuel production.
National Institutes of Health, California Energy Commission, Air Force, Department of Energy, National Science Foundation

Contact: Mario Aguilera
University of California - San Diego

Public Release: 20-Nov-2013
New crizotinib side-effect
A University of Colorado Cancer Center study published today in the journal Cancer shows that using crizotinib to treat ALK positive non-small cell lung cancer appears to reduce kidney function when assessed by one of the most commonly used clinical methods.
NIH/National Cancer Institute, National Institutes of Health

Contact: Garth Sundem
University of Colorado Denver

Public Release: 20-Nov-2013
Brain Sciences
Connections in the brains of young children strengthen during sleep, CU-Boulder study finds
While young children sleep, connections between the left and the right hemispheres of their brain strengthen, which may help brain functions mature, according to a new study by the University of Colorado Boulder.
NIH/National Insitute of Mental Health, Seprarcor Inc., Swiss National Science Foundation

Contact: Salome Kurth
University of Colorado at Boulder

Public Release: 20-Nov-2013
Aging Cell
Aging impacts epigenome in human skeletal muscle
Our epigenome is a set of chemical switches that turn parts of our genome off and on at strategic times and locations. These switches are impacted by environmental factors including diet, exercise and stress. Research at the Buck Institute reveals that aging also effects the epigenome in human skeletal muscle. The study provides a method to study sarcopenia, the degenerative loss of muscle mass that begins in middle age.
National Institutes of Health, Ellison Medical Foundation, Canadian Institutes of Health Research

Contact: Kris Rebillot
Buck Institute for Age Research

Public Release: 20-Nov-2013
Sudden steep drop in blood pressure on standing from lying down may predict atrial fibrillation
Results of a Johns Hopkins-led study have identified a possible link between a history of sudden drops in blood pressure and the most common form of irregular heartbeat.
NIH/National Heart, Lung, and Blood Institute, American Heart Association

Contact: Stephanie Desmon
Johns Hopkins Medicine

Public Release: 20-Nov-2013
Aging erodes genetic control, but that's flexible
In yeast at least, the aging process appears to reduce an organism's ability to silence certain genes that need to be silenced. Now researchers at Brown University who study the biology of aging have shown that the loss of genetic control occurs in fruit flies as well. Results appear online in the journal Aging.
NIH/National Institute on Aging, Ellison Medical Foundation

Contact: David Orenstein
Brown University

Public Release: 20-Nov-2013
Team of Chicago hospitals awarded grant to accelerate stroke research, treatments
A new network dedicated to advancing research and therapies for stroke is forming in Chicago thanks to $2 million in grants from the National Institutes of Health.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Megan McCann
Northwestern Memorial Hospital

Public Release: 20-Nov-2013
Nutrition Journal
Dartmouth-led study shows diet alone can be significant source of arsenic
Diet alone can be a significant source of arsenic exposure regardless of arsenic concentrations in drinking and cooking water, a Dartmouth College-led study finds.
NIH/National Institute of Environmental Health Sciences, NIH/National Cancer Institute, US Environmental Protection Agency

Contact: John Cramer
Dartmouth College

Public Release: 20-Nov-2013
EORTC head & neck cancer trial shows assessing HRQOL is valuable to both patients and their doctors
EORTC trial 24954 set out to compare two treatment schemes for patients with respectable hypopharyngeal and laryngeal cancers, and the results published in Cancer show that there is a trend towards worse HRQOL scores in patients receiving alternating chemoradiotherapy (alternating arm) as opposed to those given sequential induction chemotherapy and radiotherapy (sequential arm). However, very few differences reached the level of statistical significance, and most patients' HRQOL scores returned to baseline once treatment was completed.
NIH/National Cancer Institute, Fonds Cancer/FOCA, Belgium

Contact: John Bean
European Organisation for Research and Treatment of Cancer

Public Release: 20-Nov-2013
Insomnia linked to mortality risk
Insomnia, the most common sleep disorder, affects up to one-third of the population in the United States. In new findings, researchers from Brigham and Women's Hospital have found that some insomnia symptoms are associated with an increased risk of mortality in men. These findings are published online in Circulation and will appear in an upcoming print issue.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Cancer Institute, NIH/TREC

Contact: Lori J Schroth
Brigham and Women's Hospital

Public Release: 20-Nov-2013
Physical Review Letters
IUPUI study: Finding Occam's razor in an era of information overload
How to predict actions and reactions of things invisible to human eye? New study led by physicist Steve Presse, Ph.D., of the School of Science at Indiana University-Purdue University Indianapolis, shows that there may be a preferred strategy for selecting mathematical models with the greatest predictive power. Picking the best model is about sticking to the simplest line of reasoning, according to Presse. His paper explaining his theory is published online this month in Physical Review Letters.
IUPU/School of Science, NIH/National Institute of General Medical Studies

Contact: Cindy Fox Aisen
Indiana University-Purdue University Indianapolis School of Science

Public Release: 20-Nov-2013
Blood vessel tangles in brain best left alone, study suggests
Patients with a condition that causes blood vessels in the brain to form an abnormal tangle could be helped by the findings of new research.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Eleanor Cowie
University of Edinburgh

Public Release: 20-Nov-2013
Focusing on faces
Difficulties in social interaction are considered to be one of the behavioral hallmarks of autism spectrum disorders. Previous studies have shown differences in how the brains of autistic individuals process sensory information about faces. Now, a team led Caltech neuroscientist Ralph Adolphs has made the first recordings of the firings of single neurons in the brains of autistic individuals, and has found specific neurons that show reduced processing of the eye region of faces.
Simons Foundation, Moore Foundation, Cedars-Sinai Medical Center, Autism Speaks, NIH/National Institute of Mental Health

Contact: Deborah Williams-Hedges
California Institute of Technology

Public Release: 20-Nov-2013
Science Translational Medicine
Tiny antisense molecules increase 'good cholesterol' levels in obese primates
A strategy developed by Massachusetts General Hospital-based investigators to increase levels of beneficial high-density lipoprotein (HDL) has been shown for the first time to be effective in non-human primates. The approach uses tiny antisense sequences to block the action of microRNAs that would otherwise inhibit a protein required for generation of HDL, the "good cholesterol" that helps remove harmful lipids from the body.
National Institutes of Health

Contact: Sue McGreevey
Massachusetts General Hospital

Showing releases 3201-3225 out of 3510.

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