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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 3201-3225 out of 3572.

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Public Release: 5-Mar-2014
Genome Biology
An inventive new way to profile immune cells in blood
The specific proportions of immune cells in a blood sample form a profile that can indicate disease or exposure to a toxicant. A new epigenetic technique described in Genome Biology provides a reliable way to detect such profiles, even in archived blood where whole cells may no longer be intact.
National Institutes of Health, Johnson & Johnson Corporate Office of Science and Technology

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 5-Mar-2014
UTMB collaborates on program targeting potential bioterrorist pathogens Ebola and Marburg
The University of Texas Medical Branch at Galveston, Profectus Biosciences, Tekmira Pharmaceuticals and the Vanderbilt University Medical Center have been awarded up to $26 million to advance treatments of the highly lethal hemorrhagic fever viruses Ebola and Marburg.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Raul Reyes
rareyes@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston

Public Release: 5-Mar-2014
Menopause
Calcium and vitamin D improve cholesterol in postmenopausal women
Calcium and vitamin D supplements after menopause can improve women's cholesterol profiles. And much of that effect is tied to raising vitamin D levels, finds a new study from the Women's Health Initiative just published online in Menopause, the journal of the North American Menopause Society.
NIH/National Heart, Lung, and Blood Institute

Contact: Eileen Petridis
epetridis@fallscommunications.com
216-696-0229
The North American Menopause Society (NAMS)

Public Release: 5-Mar-2014
Journal of Biological Chemistry
Researchers identify key enzyme found in bacteria responsible for heart valve disease
A disease-causing bacterium found in the mouth needs manganese, a trace mineral, in order to cause a serious heart infection, according to a preclinical study led by researchers at VCU Philips Institute for Oral Health Research in the School of Dentistry.
National Institutes of Health

Contact: Sathya Achia Abraham
sbachia@vcu.edu
804-828-1231
Virginia Commonwealth University

Public Release: 5-Mar-2014
Journal of Biological Chemistry
New molecules doom proteins with kiss of death
Like mobsters following strict orders, newly engineered molecules called 'ubiquibodies' can mark specific proteins inside a cell for destruction. It's a molecular kiss of death developed at Cornell University that is paving the way for new drug therapies and powerful research tools.
National Institutes of Health

Contact: Syl Kacapyr
vpk6@cornell.edu
607-255-7701
Cornell University

Public Release: 5-Mar-2014
Development and Psychopathology
Experiential avoidance increases PTSD risk following child maltreatment
Child abuse is a reliable predictor of post-traumatic stress disorder, but not all maltreated children suffer from it, according to Chad Shenk, assistant professor of human development and family studies, Penn State, who examined why some maltreated children develop PTSD and some do not.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development

Contact: A'ndrea Elyse Messer
aem1@psu.edu
814-865-9481
Penn State

Public Release: 5-Mar-2014
Nature
ALS-linked gene causes disease by changing genetic material's shape
Johns Hopkins researchers say they have found one way that a recently discovered genetic mutation might cause two nasty nervous system diseases. While the affected gene may build up toxic RNA and not make enough protein, the researchers report in Nature that the root of the problem seems to be snarls of defective genetic material created at the mutation site.
NIH/National Institute of Neurological Disorders and Stroke, Robert Packard Center for ALS Research, Muscular Dystrophy Association, Target ALS, and others

Contact: Shawna Williams
shawna@jhmi.edu
410-955-8632
Johns Hopkins Medicine

Public Release: 5-Mar-2014
New England Journal of Medicine
Younger men benefit most from surgery for localized prostate cancer
New study finds a substantial long-term reduction in mortality for men with localized cancer who undergo a radical prostatectomy.
Swedish Cancer Society, National Institutes of Health, Karolinska Institutet, Prostate Cancer Foundation, Percy Falk Foundation

Contact: Todd Datz
tdatz@hsph.harvard.edu
617-432-8413
Harvard School of Public Health

Public Release: 5-Mar-2014
Neuron
Similarity breeds proximity in memory, NYU researchers find
Researchers at New York University have identified the nature of brain activity that allows us to bridge time in our memories. Their findings offer new insights into the temporal nature of how we store our recollections and may offer a pathway for addressing memory-related afflictions.
NIH/National Institute of Mental Health

Contact: James Devitt
james.devitt@nyu.edu
212-998-6808
New York University

Public Release: 5-Mar-2014
New England Journal of Medicine
Gene therapy locks out HIV, paving the way to control virus without antiretroviral drug
University of Pennsylvania researchers have successfully genetically engineered the immune cells of 12 HIV positive patients to resist infection, and decreased the viral loads of some patients taken off antiretroviral drug therapy entirely -- including one patient whose levels became undetectable.
NIH/National Institute of Allergy and Infectious Diseases, Penn CFAR, Sangamo

Contact: Steve Graff
stephen.graff@uphs.upenn.edu
215-349-5653
University of Pennsylvania School of Medicine

Public Release: 5-Mar-2014
Neuron
Brain circuits multitask to detect, discriminate the outside world
A new study found that neural circuits in the brain rapidly multitask between detecting and discriminating sensory input, such as car headlights in the distance. That's different from how electronic circuits work, where one circuit performs a very specific task. The brain, the study found, is wired in way that allows a single pathway to perform multiple tasks.
National Institutes of Health, National Science Foundation

Contact: Brett Israel
brett.israel@comm.gatech.edu
404-385-1933
Georgia Institute of Technology

Public Release: 4-Mar-2014
Cell Metabolism
Cholesterol study suggests new diagnostic, treatment approach for prostate cancer
Researchers have discovered a link between prostate cancer aggressiveness and the accumulation of a compound produced when cholesterol is metabolized in cells, findings that could bring new diagnostic and treatment methods. Findings also suggest that a class of drugs previously developed to treat atherosclerosis might be repurposed for treatment of advanced prostate cancer.
National Institutes of Health, National Science Foundation, US Department of Defense

Contact: Emil Venere
venere@purdue.edu
765-494-4709
Purdue University

Public Release: 4-Mar-2014
Oncotarget
Common cancers evade detection by silencing parts of immune system cells
Johns Hopkins researchers say they have identified a set of genes that appear to predict which tumors can evade detection by the body's immune system, a step that may enable them to eventually target only the patients most likely to respond best to a new class of treatment.
NIH/National Cancer Institute, Stand Up to Cancer, Epigenetic Dream Team

Contact: Stephanie Desmon
sdesmon1@jhmi.edu
410-955-8665
Johns Hopkins Medicine

Public Release: 4-Mar-2014
Brain, Behavior and Immunity
Imprint of chemotherapy linked to inflammation in breast cancer survivors
Chemotherapy can leave a long-lasting epigenetic imprint in the DNA of breast cancer patients' blood cells. That imprint is associated with biological signs of inflammation up to six months after the completion of treatment.
NIH/National Cancer Institute

Contact: Quinn Eastman
qeastma@emory.edu
404-727-7829
Emory Health Sciences

Public Release: 4-Mar-2014
Psychological Science
Young children form first impressions from faces
Just like adults, children as young as 3 tend to judge an individual's character traits, such as trustworthiness and competence, simply by looking at the person's face, new research shows. And they show remarkable consensus in the judgments they make, the findings suggest.
E.J. Safra Center for the Study of Ethics, Santa Fe Institute, National Institutes of Health

Contact: Scott Sleek
ssleek@psychologicalscience.org
202-293-9300
Association for Psychological Science

Public Release: 4-Mar-2014
Nature Communications
Silk-based surgical implants could offer a better way to repair broken bones
Using pure silk protein derived from silkworm cocoons, investigators have developed surgical plates and screws that offer improved remodeling following injury and can be absorbed by the body over time.
National Institutes of Health

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center

Public Release: 4-Mar-2014
Molecular Cancer Research
TGen identifies key protein that helps prevent lung cancer tumors from being destroyed
Researchers at the Translational Genomics Research Institute have discovered a protein, Mcl-1, that helps enable one of the most common and deadly types of cancer to survive radiation and drug treatments. In a new laboratory study published in the scientific journal Molecular Cancer Research, TGen investigators found that a protein called Mcl-1 helps enable TWEAK-Fn14, which in turn helps protect NSCLC tumors from being destroyed by radiation and drugs.
National Institutes of Health

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Public Release: 4-Mar-2014
American Journal of Human Genetics
CHOP researcher finds more genetic signals linking weight and heart health risk factors
Two recent genetic studies expand the list of genes involved with body fat and body mass index, and their connection to major Western health problems: heart disease, high blood pressure and diabetes. One study showed that higher body mass index caused harmful effects on the risk of type 2 diabetes, high blood pressure and inflammation, while another study found gene signals linked to higher levels of body fat metrics, without showing causality.
NIH/National Heart, Lung and Blood Institute

Contact: John Ascenzi
ascenzi@email.chop.edu
267-426-6055
Children's Hospital of Philadelphia

Public Release: 4-Mar-2014
21st Conference on Retroviruses and Opportunistic Infections
Study comparing injectable contraceptives DMPA and NET-EN finds HIV risk higher with DMPA
Women who used an injectable contraceptive called DMPA were more likely to acquire HIV than women using a similar product called NET-EN, according to a secondary analysis of data from a large HIV prevention trial called VOICE. The new analysis, conducted by researchers from the NIH-funded Microbicide Trials Network, is the first head-to-head observational study to directly compare differences in HIV risk between users of DMPA and NET-EN.
National Institutes of Health

Contact: Lisa Rossi
rossil@upmc.edu
412-916-3315
Microbicide Trials Network

Public Release: 4-Mar-2014
American Journal of Epidemiology
Study finds experiences of racism associated with weight gain in African American women
A recent analysis conducted by investigators from the Slone Epidemiology Center at Boston University has found that frequent experiences of racism were associated with a higher risk of obesity among African American women. The findings, which currently appear online in the American Journal of Epidemiology, found the relationship between racism and obesity was strongest among women who reported consistently high experiences of racism over a 12-year period.
Aetna Foundation, NIH/National Cancer Institute

Contact: Gina DiGravio
gina.digravio@bmc.org
617-638-8480
Boston University Medical Center

Public Release: 4-Mar-2014
39th AIAA Dayton-Cincinnati Aerospace Sciences Symposium
Research benefits surgeons making decisions on how to help their patients breathe easier
UC researchers use computer simulations developed for aircraft design to improve treatment of human airways.
National Institutes of Health

Contact: Dawn Fuller
dawn.fuller@uc.edu
513-556-1823
University of Cincinnati

Public Release: 4-Mar-2014
21st Conference on Retroviruses and Opportunistic Infections
Behavioral measures of product use didn't measure up in VOICE HIV prevention trial
A new analysis from the NIH-funded Microbicide Trials Network confirms what they and others had already assumed: The behavioral measures used for assessing adherence in the VOICE study -- an HIV prevention trial involving more than 5,000 women in sub-Saharan Africa -- did not provide accurate information about women's use and nonuse of the products being tested. In fact, these tools were not much better than chance at being able to predict adherence to product use.
National Institutes of Health

Contact: Lisa Rossi
rossil@upmc.edu
412-916-3315
Microbicide Trials Network

Public Release: 4-Mar-2014
21st Conference on Retroviruses and Opportunistic Infections
Combination ARV vaginal ring to prevent HIV safe in trial but 1 ARV carries the weight
An early phase clinical trial of a vaginal ring containing the antiretroviral (ARV) drugs dapivirine and maraviroc found the ring was safe in women who wore it for 28 days and evidence of dapivirine in cervical tissue and blood. In addition, laboratory tests of tissue samples showed that dapivirine was able to block HIV infection, though levels of maraviroc were not sufficient to have a similar effect, report researchers from the Microbicide Trials Network.
National Institutes of Health

Contact: Lisa Rossi
rossil@upmc.edu
412-916-3315
Microbicide Trials Network

Public Release: 4-Mar-2014
Proceedings of the National Academy of Sciences
Brandeis University researchers illuminate key structure in heart cells
Brandeis University researchers have unlocked the structure of potassium ion channels that regulate contractions in the heart. The research may help create more effective models to study heart conditions, such as arrhythmias, and their treatment.
National Institutes of Health

Contact: Leah Burrows
lburrows@brandeis.edu
781-736-4027
Brandeis University

Public Release: 4-Mar-2014
Proceedings of the National Academy of Sciences
New probes from Scripps research quantify folded and misfolded protein levels in cells
Scientists at The Scripps Research Institute have invented small-molecule folding probes that enable them to quantify functional, normally folded and disease-associated misfolded conformations (shapes) of a protein-of-interest in cells under different conditions.
National Institutes of Health, Skaggs Institute for Chemical Biology, Lita Annenberg Hazen Foundation

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Showing releases 3201-3225 out of 3572.

<< < 124 | 125 | 126 | 127 | 128 | 129 | 130 | 131 | 132 | 133 > >>

     
   

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