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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3226-3250 out of 3544.

<< < 125 | 126 | 127 | 128 | 129 | 130 | 131 | 132 | 133 | 134 > >>

Public Release: 6-Jan-2014
Proceedings of the National Academy of Sciences
Biomaterials get stem cells to commit to a bony future
With the help of biomimetic matrices, a research team led by bioengineers at the University of California, San Diego has discovered exactly how calcium phosphate can coax stem cells to become bone-building cells. This work is published in the Proceedings of the National Academy of Sciences the week of Jan. 6, 2014.
National Institutes of Health, Taiwan National Science Council

Contact: Daniel Kane
University of California - San Diego

Public Release: 5-Jan-2014
Yeast's lifestyle couples mating with meiosis
Mating and meiosis -- the specialized cell division that reduces the number of chromosomes in a cell -- are related, but in most yeasts they are regulated separately. Not so in Candida lusitaniae, where the two programs work in unison, according to a new study in Nature. Comparison with other species suggests that this fusion may support C. lusitaniae's "haploid lifestyle" of maintaining only one set of chromosomes in each cell.
National Science Foundation, National Institutes of Health, Burroughs Wellcome

Contact: David Orenstein
Brown University

Public Release: 3-Jan-2014
Loss of function of a single gene linked to diabetes in mice
Researchers from the University of Illinois at Chicago College of Medicine have found that dysfunction in a single gene in mice causes fasting hyperglycemia, one of the major symptoms of Type 2 diabetes. Their findings were reported online in the journal Diabetes.
National Institutes of Health

Contact: Sharon Parmet
University of Illinois at Chicago

Public Release: 3-Jan-2014
Parkinson's patients utilization of deep brain stimulation treatment reduced in demographic groups
Among Parkinson's disease patients, female, black, and Asian patients are substantially less likely to receive proven deep brain stimulation (DBS) surgery to improve tremors and motor symptoms, according to a new report by a Perelman School of Medicine at the University of Pennsylvania researcher who identified considerable disparities among Medicare recipients receiving DBS for Parkinson's disease.
National Institutes of Health, St. Louis Chapter-American Parkinson Disease Association

Contact: Kim Menard
University of Pennsylvania School of Medicine

Public Release: 2-Jan-2014
American Journal of Medicine
Patch outperforms Holter for prolonged heart rhythm tracking
Research by the Scripps Translational Science Institute has found that a small adhesive wireless device worn on the chest for up to two weeks does a better job detecting abnormal and potentially dangerous heart rhythms than the Holter monitor, which is typically used for 24 hours and has been the standard of care for more than 50 years.
National Institutes of Health, iRhythm Technologies

Contact: Keith Darce
Scripps Health

Public Release: 2-Jan-2014
Genetically identical bacteria can behave in radically different ways
When a bacterial cell divides into two daughter cells there can be an uneven distribution of certain survival mechanisms. The resulting cells can behave differently from each other, depending on which parts they received in the split. This is another way that cells within a population can diversify and enhance the odds that some members of a population of bacteria can avoid threats, such as antibiotics.
NIH/National Institute of Allergy and Infectious Diseases, National Institutes of Health, National Science Foundation

Contact: Leila Gray
University of Washington

Public Release: 2-Jan-2014
PLOS Pathogens
Study explaining parasite gene expression could help fight toxoplasmosis and malaria
A newly identified protein and other proteins it interacts with could become effective targets for new drugs to control the parasite that cause toxoplasmosis, researchers reported.
National Institutes of Health

Contact: Eric Schoch
Indiana University

Public Release: 2-Jan-2014
New MRI technique illuminates the wrist in motion
UC Davis radiologists, medical physicists and orthopaedic surgeons have found a way to create "movies" of the wrist in motion using a series of brief magnetic resonance imaging scans.
National Institutes of Health

Contact: Karen Finney
University of California - Davis Health System

Public Release: 2-Jan-2014
Animal cells can communicate by reaching out and touching, UCSF team discovers
In a finding that directly contradicts the standard biological model of animal cell communication, UCSF scientists have discovered that typical cells in animals have the ability to transmit and receive biological signals by making physical contact with each other, even at long distance.
National Institutes of Health

Contact: Peter Farley
University of California - San Francisco

Public Release: 2-Jan-2014
Proceedings of the National Academy of Sciences
The mouse that ROR'ed
Researchers at the University of California, San Diego School of Medicine report that an oncogene dubbed ROR1, found on chronic lymphocytic leukemia (CLL) B cells but not normal adult tissues, acts as an accelerant when combined with another oncogene, resulting in a faster-developing, more aggressive form of CLL in mice.
National Institutes of Health, California Institute for Regenerative Medicine

Contact: Scott LaFee
University of California - San Diego

Public Release: 2-Jan-2014
Current Biology
Chinese herbal compound relieves inflammatory and neuropathic pain
A compound derived from a traditional Chinese herbal medicine has been found effective at alleviating pain, pointing the way to a new nonaddictive analgesic for acute inflammatory and nerve pain, according to UC Irvine pharmacology researchers.
National Institutes of Health

Contact: Tom Vasich
University of California - Irvine

Public Release: 2-Jan-2014
Cell Reports
New cell mechanism discovery key to stopping breast cancer metastasis
Researchers from Huntsman Cancer Institute at the University of Utah discovered a cellular mechanism that drives the spread of breast cancer to other parts of the body (metastasis), as well as a therapy which blocks that mechanism.
NIH/National Cancer Institute

Contact: Linda Aagard
University of Utah Health Sciences

Public Release: 2-Jan-2014
ACS Chemical Biology
Scientists uncover image of muscular dystrophy defect & design targeted drug candidates
Scientists from the Florida campus of The Scripps Research Institute have revealed an atomic-level view of a genetic defect that causes a form of muscular dystrophy, myotonic dystrophy type 2, and have used this information to design drug candidates with potential to counter those defects -- and reverse the disease.
National Institutes of Health, Muscular Dystrophy Association

Contact: Eric Sauter
Scripps Research Institute

Public Release: 2-Jan-2014
Therapeutic Advances in Cardiovascular Disease
High blood pressure potentially more dangerous for women than men
Doctors may need to treat high blood pressure in women earlier and more aggressively than they do in men, according to scientists at Wake Forest Baptist Medical Center.
NIH/National Heart, Blood, Lung Institute

Contact: Marguerite Beck
Wake Forest Baptist Medical Center

Public Release: 2-Jan-2014
Cell Stem Cell
Biologists discover solution to problem limiting development of human stem cell therapies
Biologists at UC San Diego have discovered an effective strategy that could prevent the human immune system from rejecting the grafts derived from human embryonic stem cells, a major problem now limiting the development of human stem cell therapies.
National Institutes of Health, California Institute for Regenerative Medicine

Contact: Kim McDonald
University of California - San Diego

Public Release: 2-Jan-2014
Journal of Clinical Investigation
Doxorubicin-associated mitochondrial iron accumulation promotes cardiotoxicity
In this issue of the Journal of Clinical Investigation, Hossein Ardehali and colleagues at Northwestern University determined that doxorubicin accumulates within the mitochondria of cardiomyocytes and this accumulation promotes mitochondrial ROS production and iron accumulation.
National Institutes of Health, NIH/National Cancer Institute

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 2-Jan-2014
Journal of Clinical Investigation
Opioid tolerance and pain hypersensitivity associated with mTOR activation
In this issue of the Journal of Clinical Investigation, Yuan-Xiang Tao and colleagues from the New Jersey Medical School at Rutgers University report that the protein mTOR, which is a global regulator of translation, plays a major role in morphine tolerance.
National Institutes of Health, Rita Allen Foundation, National Natural Science Foundation of China

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 1-Jan-2014
JAMA Psychiatry
Alcohol, tobacco, drug use far higher in severely mentally ill
Researchers at Washington University School of Medicine in St. Louis and the University of Southern California have found that rates of smoking, drinking and drug use are significantly higher among those who have psychotic disorders than in the general population. And that finding is of particular concern because individuals with severe mental illness are more likely to die at younger ages than people who don't have psychiatric disorders.
NIH/National Institute on Drug Abuse, NIH/National Institute on Alcohol Abuse and Alcoholism, NIH/National Institute of Mental Health, NIH/National Cancer Institute, American Cancer Society

Contact: Jim Dryden
Washington University School of Medicine

Public Release: 31-Dec-2013
GRU joins national research cooperative to improve reproductive health
Georgia Regents University has joined the national Cooperative Multicenter Reproductive Medicine Network designed to enable large clinical trials that improve the diagnosis and treatment of reproductive health issues such as male and female infertility.
National Institutes of Health

Contact: Toni Baker
Medical College of Georgia at Georgia Regents University

Public Release: 30-Dec-2013
ACS Nano
Imaging technology could unlock mysteries of a childhood disease
A new technique for studying the structure of the childhood RSV virus and its activity in living cells could help researchers unlock the secrets of the virus, including how it enters cells, how it replicates, and perhaps why certain lung cells escape the infection relatively unscathed.
National Institutes of Health, NIH/National Institute of General Medical Sciences

Contact: John Toon
Georgia Institute of Technology

Public Release: 30-Dec-2013
American Journal of Transplantation
Study identifies potential new strategy to improve odds of corneal transplant acceptance
For the estimated 10 percent of patients whose bodies reject a corneal transplant, the odds of a second transplant succeeding are poor. All that could change, however, based on a UT Southwestern Medical Center study that has found a way to boost the corneal transplant acceptance rate.
National Institutes of Health, Research to Prevent Blindness

Contact: Debbie Bolles
UT Southwestern Medical Center

Public Release: 30-Dec-2013
Proceedings of the National Academy of Sciences
Testosterone in male songbirds may enhance desire to sing but not song quality
Introducing testosterone in select areas of a male canary's brain can affect its ability to successfully attract and mate with a female through birdsong. These findings could shed light on how testosterone acts in the human brain to regulate speech or help explain how anabolic steroids affect human behaviors.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Latarsha Gatlin
Johns Hopkins University

Public Release: 30-Dec-2013
JAMA Neurology
High good and low bad cholesterol levels are healthy for the brain, too
High levels of "good" cholesterol and low levels of "bad" cholesterol are correlated with lower levels of the amyloid plaque deposition in the brain that is a hallmark of Alzheimer's disease, in a pattern that mirrors the relationship between good and bad cholesterol in cardiovascular disease, UC Davis researchers have found.
NIH/National Institute on Aging, Canadian Institutes of Health

Contact: Phyllis Brown
University of California - Davis Health System

Public Release: 30-Dec-2013
JAMA Pediatrics
Conversations on sex lacking between doctors and teens
Doctors are missing a prime opportunity to share information about sex with their teenage patients by failing to broach the subject during checkups, according to researchers at Duke Medicine.
NIH/National Heart, Lung and Blood Institute

Contact: Rachel Harrison
Duke University Medical Center

Public Release: 30-Dec-2013
Journal of General Physiology
Nicotine exploits COPI to foster addiction
A study in the Journal of General Physiology helps explain how nicotine exploits the body's cellular machinery to promote addiction. The findings could lead to new therapies to help people quit smoking.
National Institutes of Health, California Tobacco-Related Disease Research Program

Contact: Rita Sullivan King
Rockefeller University Press

Showing releases 3226-3250 out of 3544.

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