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Department of Health and Human Services

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Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 3226-3250 out of 3508.

<< < 125 | 126 | 127 | 128 | 129 | 130 | 131 | 132 | 133 | 134 > >>

Public Release: 20-Nov-2013
Aging
Aging erodes genetic control, but that's flexible
In yeast at least, the aging process appears to reduce an organism's ability to silence certain genes that need to be silenced. Now researchers at Brown University who study the biology of aging have shown that the loss of genetic control occurs in fruit flies as well. Results appear online in the journal Aging.
NIH/National Institute on Aging, Ellison Medical Foundation

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 20-Nov-2013
Team of Chicago hospitals awarded grant to accelerate stroke research, treatments
A new network dedicated to advancing research and therapies for stroke is forming in Chicago thanks to $2 million in grants from the National Institutes of Health.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Megan McCann
memccann@nmh.org
312-926-5900
Northwestern Memorial Hospital

Public Release: 20-Nov-2013
Nutrition Journal
Dartmouth-led study shows diet alone can be significant source of arsenic
Diet alone can be a significant source of arsenic exposure regardless of arsenic concentrations in drinking and cooking water, a Dartmouth College-led study finds.
NIH/National Institute of Environmental Health Sciences, NIH/National Cancer Institute, US Environmental Protection Agency

Contact: John Cramer
john.cramer@dartmouth.edu
603-646-9130
Dartmouth College

Public Release: 20-Nov-2013
Cancer
EORTC head & neck cancer trial shows assessing HRQOL is valuable to both patients and their doctors
EORTC trial 24954 set out to compare two treatment schemes for patients with respectable hypopharyngeal and laryngeal cancers, and the results published in Cancer show that there is a trend towards worse HRQOL scores in patients receiving alternating chemoradiotherapy (alternating arm) as opposed to those given sequential induction chemotherapy and radiotherapy (sequential arm). However, very few differences reached the level of statistical significance, and most patients' HRQOL scores returned to baseline once treatment was completed.
NIH/National Cancer Institute, Fonds Cancer/FOCA, Belgium

Contact: John Bean
john.bean@eortc.be
European Organisation for Research and Treatment of Cancer

Public Release: 20-Nov-2013
Circulation
Insomnia linked to mortality risk
Insomnia, the most common sleep disorder, affects up to one-third of the population in the United States. In new findings, researchers from Brigham and Women's Hospital have found that some insomnia symptoms are associated with an increased risk of mortality in men. These findings are published online in Circulation and will appear in an upcoming print issue.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Cancer Institute, NIH/TREC

Contact: Lori J Schroth
ljschroth@partners.org
617-525-6374
Brigham and Women's Hospital

Public Release: 20-Nov-2013
Physical Review Letters
IUPUI study: Finding Occam's razor in an era of information overload
How to predict actions and reactions of things invisible to human eye? New study led by physicist Steve Presse, Ph.D., of the School of Science at Indiana University-Purdue University Indianapolis, shows that there may be a preferred strategy for selecting mathematical models with the greatest predictive power. Picking the best model is about sticking to the simplest line of reasoning, according to Presse. His paper explaining his theory is published online this month in Physical Review Letters.
IUPU/School of Science, NIH/National Institute of General Medical Studies

Contact: Cindy Fox Aisen
caisen@iupui.edu
Indiana University-Purdue University Indianapolis School of Science

Public Release: 20-Nov-2013
Lancet
Blood vessel tangles in brain best left alone, study suggests
Patients with a condition that causes blood vessels in the brain to form an abnormal tangle could be helped by the findings of new research.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Eleanor Cowie
Eleanor.Cowie@ed.ac.uk
44-131-650-6382
University of Edinburgh

Public Release: 20-Nov-2013
Neuron
Focusing on faces
Difficulties in social interaction are considered to be one of the behavioral hallmarks of autism spectrum disorders. Previous studies have shown differences in how the brains of autistic individuals process sensory information about faces. Now, a team led Caltech neuroscientist Ralph Adolphs has made the first recordings of the firings of single neurons in the brains of autistic individuals, and has found specific neurons that show reduced processing of the eye region of faces.
Simons Foundation, Moore Foundation, Cedars-Sinai Medical Center, Autism Speaks, NIH/National Institute of Mental Health

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology

Public Release: 20-Nov-2013
Science Translational Medicine
Tiny antisense molecules increase 'good cholesterol' levels in obese primates
A strategy developed by Massachusetts General Hospital-based investigators to increase levels of beneficial high-density lipoprotein (HDL) has been shown for the first time to be effective in non-human primates. The approach uses tiny antisense sequences to block the action of microRNAs that would otherwise inhibit a protein required for generation of HDL, the "good cholesterol" that helps remove harmful lipids from the body.
National Institutes of Health

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital

Public Release: 20-Nov-2013
PLOS ONE
Study is first to explain type of antimalarial drug resistance
This study explores why drugs designed to fight off malaria stop working in some people with the disease. Researchers found genetic and cell biological evidence linking autophagy to resistance to the parasite. Autophagy is the process by which cells remove damaged parts of themselves to restore normal function. In this case, the cell rids itself of the parts damaged by the antimalarial drug.
National Institutes of Health, Kentucky Science and Engineering Foundation

Contact: Maggie Moore
mem95@georgetown.edu
Georgetown University Medical Center

Public Release: 20-Nov-2013
JAMA Psychiatry
PTSD raises risk for obesity in women
Women with post-traumatic stress disorder (PTSD) gain weight more rapidly and are more likely to be overweight or obese than women without the disorder, find researchers at Columbia University's Mailman School of Public Health and Harvard School of Public Health. It is the first study to look at the relationship between PTSD and obesity over time. Results appear online in JAMA Psychiatry.
NIH/National Institute of Mental Health

Contact: Timothy S. Paul
tp2111@columbia.edu
212-305-2676
Columbia University's Mailman School of Public Health

Public Release: 20-Nov-2013
British Medical Journal
Top hospitals reduce readmissions by preventing complications across all diagnoses
Checking back into the hospital within 30 days of discharge is not only bad news for patients, but also for hospitals, which now face financial penalties for high readmissions. The key to reducing readmissions may be focusing on the whole patient, rather than the specific conditions that caused their hospitalizations, according to a new study by Yale School of Medicine researchers.
NIH/National Heart, Lung, and Blood Institute

Contact: Karen N. Peart
karen.peart@yale.edu
203-980-2222
Yale University

Public Release: 20-Nov-2013
2013 American Heart Association Scientific Session
Mental stress + heart disease: Stronger presence in women under 50
Researchers have found that women younger than 50 with a recent heart attack are more likely to experience restricted blood flow to the heart (myocardial ischemia) in response to psychological stress.
NIH/National Heart, Lung, and Blood Institute, NIH/National Institute of Mental Health

Contact: Jennifer Johnson
jrjohn9@emory.edu
404-727-5696
Emory Health Sciences

Public Release: 20-Nov-2013
Scientific Translational Medicine
Study reveals how variant forms of APOE protein impact risk of Alzheimer's disease
Massachusetts General Hospital investigators have shown that even low levels of the Alzheimer's-associated APOE4 protein can increase the number and density of amyloid brain plaques, related neuronal damage, and the amount of soluble amyloid within the brain in mouse models of the disease. APOE2, a rare variant that has been associated with protection from Alzheimer's of actually reduced A-beta deposition, retention and neurotoxicity, suggesting the potential for gene-therapy-based treatment.
National Institutes of Health, Dreyfoos Program

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital

Public Release: 20-Nov-2013
New England Journal of Medicine
Current practice may over-diagnose vitamin D deficiency
The current "gold standard" test for measuring vitamin D status may not accurately diagnose vitamin D deficiency in black individuals. A team of researchers has found that genetic differences in a vitamin D carrier protein may explain the discrepancy between the prevalence of diagnosed vitamin D deficiency in black Americans and a lack of the usual symptoms of vitamin deficiency.
National Institutes of Health

Contact: Cassandra Aviles
cmaviles@partners.org
617-724-6433
Massachusetts General Hospital

Public Release: 20-Nov-2013
Neuron
Neurons in brain's 'face recognition center' respond differently in patients with autism
In what are believed to be the first studies of their kind, Cedars-Sinai researchers recording the real-time firing of individual nerve cells in the brain found that a specific type of neuron in a structure called the amygdala performed differently in people who suffer from autism spectrum disorder than in those who do not.
Cedars-Sinai Medical Center, NIH/National Institute of Mental Health, and others

Contact: Sandy Van
sandy@prpacific.com
808-526-1708
Cedars-Sinai Medical Center

Public Release: 19-Nov-2013
eLife
Discovery of brain activity in severely brain injured patients who 'wake up' with sleep drug
George Melendez has been called a medical miracle. After a near drowning deprived his brain of oxygen, Melendez remained in a fitful, minimally conscious state until his mother, in 2002, decided to give him the sleep aid drug Ambien to quiet his moaning and writhing. The next thing she knew, her son was quietly looking at her and trying to talk. He has been using the drug ever since to maintain awareness, but no one could understand why Ambien led to such an awakening.
James S. McDonnell Foundation, National Institutes of Health, NIH/Eunice Kennedy Shriver National Institute of Child Health

Contact: Jennifer Gundersen
jeg2034@med.cornell.edu
646-317-7402
Weill Cornell Medical College

Public Release: 19-Nov-2013
Science
Staphylococcus aureus bacteria turns immune system against itself
Around 20 percent of all humans are persistently colonized with Staphylococcus aureus bacteria, a leading cause of skin infections and one of the major sources of hospital-acquired infections, including the antibiotic-resistant strain MRSA. University of Chicago scientists have recently discovered one of the keys to the immense success of S. aureus -- the ability to hijack a primary human immune defense mechanism and use it to destroy white blood cells. The study was published Nov 15 in Science.
NIH/National Institute of Allergy and Infectious Diseases, American Heart Association

Contact: Kevin Jiang
kevin.jiang@uchospitals.edu
773-795-5227
University of Chicago Medical Center

Public Release: 19-Nov-2013
2013 American Heart Association Scientific Session
New England Journal of Medicine
New study finds no benefit to selecting dose of blood thinner based on patients' genetic makeup
A new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania has determined that a gene-based method for selecting patients' doses of the popular heart medication warfarin is no better than standardized dosing methods. The study was presented today at the 2013 Scientific Sessions of the American Heart Association and published simultaneously in the New England Journal of Medicine.
NIH/National Heart, Lung, and Blood Institute

Contact: Jessica Mikulski
jessica.mikulski@uphs.upenn.edu
215-796-4829
University of Pennsylvania School of Medicine

Public Release: 19-Nov-2013
Nature
HIV virus spread and evolution studied through computer modeling
Researchers at Los Alamos National Laboratory are investigating the complex relationships between the spread of the HIV virus in a population (epidemiology) and the actual, rapid evolution of the virus (phylogenetics) within each patient's body.
National Institutes of Health

Contact: Nancy Ambrosiano
nwa@lanl.gov
505-667-0471
DOE/Los Alamos National Laboratory

Public Release: 19-Nov-2013
Animal Cognition
Monkeys can point to objects they do not report seeing
Are monkeys, like humans, able to ascertain where objects are located without much more than a sideways glance? Quite likely, says Lau Andersen of the Aarhus University in Denmark, lead author of a study conducted at the Yerkes National Primate Research Center of Emory University, published in Springer's journal Animal Cognition. The study finds that monkeys are able to localize stimuli they do not perceive.
NIH/National Institute of Mental Health, National Science Foundation, NIH/National Center for Research Resources

Contact: Alexander Brown
alexander.brown@springer.com
212-620-8063
Springer Science+Business Media

Public Release: 19-Nov-2013
2013 American Heart Association Scientific Session
New England Journal of Medicine
Study may impact guidelines for mitral valve surgery for severe ischemic mitral regurgitation
Study reports for the first time evidence on whether or not there is any significant difference between the two current surgical approaches to treat patients with severe ischemic mitral regurgitation -- mitral valve repair and mitral valve replacement.
National Institutes of Health

Contact: Lauren Woods
lauren.woods@mountsinai.org
646-634-0869
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 19-Nov-2013
2013 American Heart Association Scientific Session
LVAD patients benefit from heart injection with millions of powerful cells
End-stage heart failure patients who receive a surgically implanted left ventricular assist device heart pump may also benefit from a single dose of millions of powerful cells injected directly into their heart during surgery.
National Institutes of Health

Contact: Lauren Woods
lauren.woods@mountsinai.org
646-634-0869
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 19-Nov-2013
2013 American Heart Association Scientific Session
New study reports on the high cost of cardiac surgery healthcare associated infections
After cardiac surgery, healthcare-associated infections are common complications associated with increased morbidity, mortality, and use of resources. New study findings reveal the substantial economic impact of HAIs following cardiac surgery and the importance of preventing these infections leading to re-hospitalizations.
National Institutes of Health, InHealth

Contact: Lauren Woods
Lauren.woods@mountsinai.org
646-634-0869
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 19-Nov-2013
Frontiers in Neurology
Blood test accurately diagnoses concussion and predicts long term cognitive disability
A new blood biomarker correctly predicted which concussion victims went on to have white matter tract structural damage and persistent cognitive dysfunction following a mild traumatic brain injury. If validated in larger studies, this blood test could identify concussion patients at increased risk for persistent cognitive dysfunction or further brain damage and disability if returning to sports or military activities.
NIH/National Institute of Neurologic Disorders and Stroke

Contact: Kim Menard
kim.menard@uphs.upenn.edu
215-662-6183
University of Pennsylvania School of Medicine

Showing releases 3226-3250 out of 3508.

<< < 125 | 126 | 127 | 128 | 129 | 130 | 131 | 132 | 133 | 134 > >>

     
   

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