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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3226-3250 out of 3799.

<< < 125 | 126 | 127 | 128 | 129 | 130 | 131 | 132 | 133 | 134 > >>

Public Release: 26-Sep-2014
Geisel researchers contribute to study of trained immunity
A study published in the journal Science provides support for a new -- and still controversial -- understanding of the immune system. The research was conducted by collaborators in the US and Europe, including Robert Cramer, Ph.D., an assistant professor of microbiology and immunology at Dartmouth's Geisel School of Medicine.
NIH/National Institute of General Medical Sciences, NIH/National Institute of Allergy and Infectious Diseases

Contact: Derik Hertel
The Geisel School of Medicine at Dartmouth

Public Release: 26-Sep-2014
Policies of NIH, other funders, have improved data-sharing by life-science investigators
Policies put into place by major funding agencies like the National Institutes of Health, and to a lesser extent by scientific journals, appear to be meeting the goal of increasing the sharing of scientific resources among life science investigators.
NIH/National Human Genome Research Institute

Contact: Terri Ogan
Massachusetts General Hospital

Public Release: 25-Sep-2014
With NIH grant, Cedars-Sinai helps bring big data to neuro disease research
Investigators at the Cedars-Sinai Board of Governors Regenerative Medicine Institute have received a grant from the National Institutes of Health to participate in a consortium taking the study of motor neuron disorders -- such as Lou Gehrig's disease and spinal muscular atrophy -- to a new, comprehensive perspective.
National Institutes of Health

Contact: Sandy Van
Cedars-Sinai Medical Center

Public Release: 25-Sep-2014
After watching disturbing video, CPAP usage soars
It's estimated that more than 20 million Americans have sleep apnea, and if you're one of them, you may have been given a mask to wear overnight to help you breathe. They're called CPAP masks, and even though they can be extremely effective, more than half of all patients who have them don't use them. Now, doctors at National Jewish Health have found a way to change that.
National Institutes of Health

Contact: Shannon McCormick
National Jewish Health

Public Release: 25-Sep-2014
National team awarded $16 million NIH grant to study genetics of schizophrenia and bipolar disorder
A multi-institutional team of researchers studying schizophrenia and bipolar disorder has been awarded a $16 million grant from the National Institute of Mental Health to create the most extensive genetic resource to date for these two devastating psychiatric disorders, using data assembled by the University of Southern California.
NIH/National Institute of Mental Health

Contact: Alison Trinidad
University of Southern California - Health Sciences

Public Release: 25-Sep-2014
Addiction Science & Clinical Practice
BUSM researchers find NAS treatment needs standardization
When it comes to treating infants with neonatal abstinence syndrome (NAS), researchers from Boston University School of Medicine believe the care for these infants should be consistent and objective, with standardized assessment tools and evidence to back up pharmacologic and nonpharmacologic treatment choices.
NIH/National Institute on Drug Abuse

Contact: Jenny Eriksen Leary
Boston University Medical Center

Public Release: 25-Sep-2014
Researchers engineer 'Cas9' animal models to study disease and inform drug discovery
Researchers from the Broad Institute and Massachusetts Institute of Technology have created a new mouse model to simplify application of the CRISPR-Cas9 system for in vivo genome editing experiments. The researchers successfully used the new 'Cas9 mouse' model to edit multiple genes in a variety of cell types, and to model lung adenocarcinoma, one of the most lethal human cancers. A paper describing this new model and its initial applications appears this week in Cell.
National Science Foundation, The Damon Runyon Cancer Research Institute, MIT/Simons Center for the Social Brain, NIH/National Human Genome Research Institute, NIH/National Cancer Institute, NIH/National Institute of Mental Health

Contact: Haley Bridger
Broad Institute of MIT and Harvard

Public Release: 25-Sep-2014
Cancer Cell
USC researchers discover dual purpose of cancer drug in regulating expression of genes
Keck Medicine of USC scientists have discovered new clues about a drug instrumental in treating a certain blood cancer that may provide important targets for researchers searching for cures.
National Institutes of Health

Contact: Leslie Ridgeway
University of Southern California - Health Sciences

Public Release: 25-Sep-2014
Clinical Gastroenterology and Hepatology
Risk of esophageal cancer decreases with height
Taller individuals are less likely to develop esophageal cancer and it's precursor, Barrett's esophagus, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.
National Institutes of Health

Contact: Rachel Steigerwald
American Gastroenterological Association

Public Release: 25-Sep-2014
Journal of Clinical Investigation
Genes causing pediatric glaucoma contribute to future stroke
A study from the University of Alberta, published in the Journal of Clinical Investigation extends knowledge of stroke's genetic underpinnings and demonstrates that in some cases it originates in infancy.
Canadian Institutes of Health Research, Heart and Stroke Foundation, Natural Sciences and Engineering Research Council, National Institutes of Health

Contact: Ross Neitz
University of Alberta Faculty of Medicine & Dentistry

Public Release: 25-Sep-2014
Psychosomatic Medicine
Coping techniques help patients with COPD improve mentally, physically
Coaching patients with chronic obstructive pulmonary disease to manage stress, practice relaxation and participate in light exercise can boost a patient's quality of life and can even improve physical symptoms, researchers at Duke Medicine report.
National Institutes of Health

Contact: Samiha Khanna
Duke University Medical Center

Public Release: 25-Sep-2014
Plant Cell
Researchers uncover structure of enzyme that makes plant cellulose
Purdue researchers have discovered the structure of the enzyme that makes cellulose, a finding that could lead to easier ways of breaking down plant materials to make biofuels and other products and materials.
Center for the Direct Catalytic Conversion of Biomass to Biofuels, National Science Foundation, National Institutes of Health, National Research Foundation of Korea

Contact: Natalie van Hoose
Purdue University

Public Release: 25-Sep-2014
How the ends of chromosomes are maintained for cancer cell immortality
Maintaining telomeres is a requisite feature of cells that are able to continuously divide and also a hallmark of human cancer. Telomeres are much like the plastic cap on the ends of shoelaces -- they keep the ends of DNA from fraying. In a new study published this week in Cell, researchers describe a mechanism for how cancer cells take over one of the processes for telomere maintenance to gain an infinite lifespan.
NIH/National Cancer Institute, NIH/National Institute for General Medical Sciences, Abramson Cancer Research Institute, Basser Research Center for BRCA

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 25-Sep-2014
Surprising diversity of antibody family provides clues for HIV vaccine design
Scientists at The Scripps Research Institute have described how a single family of antibodies that broadly neutralizes different strains of HIV has evolved remarkably diverse structures to attack a vulnerable site on the virus. The findings provide clues for the design of a future HIV vaccine.
International AIDS Vaccine Initiative Neutralizing Antibody Center, Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, HIV Vaccine Research and Design Program, National Institutes of Health

Contact: Madeline McCurry-Schmidt
Scripps Research Institute

Public Release: 25-Sep-2014
Cell Reports
NYU Langone scientists identify key factor that maintains stem cell identity
A protein implicated in several cancers appears to play a pivotal role in keeping stem cells in an immature 'pluripotent' state, according to a new study by NYU Langone Medical Center scientists.
New York Stem Cell Foundation, Lady Tata Memorial Trust for Leukemia, American Society of Hematology, Leukemia & Lymphoma Society, NIH/National Cancer Institute, National Institutes of Health

Contact: Jim Mandler
NYU Langone Medical Center / New York University School of Medicine

Public Release: 25-Sep-2014
American Journal of Human Genetics
Large study pinpoints synapse genes with major roles in severe childhood epilepsies
An international research team has identified gene mutations causing severe, difficult-to-treat forms of childhood epilepsy. Many of the mutations disrupt functioning in the synapse, the highly dynamic junction at which nerve cells communicate with one another.
National Institutes of Health, European Science Foundation, The Andrew's Foundation

Contact: John Ascenzi
Children's Hospital of Philadelphia

Public Release: 25-Sep-2014
Cell Reports
New protein players found in key disease-related metabolic pathway
Cells rely on the mechanistic target of rapamycin complex 1 (mTORC1) pathway -- which senses the availability of nutrients -- to coordinate their growth with existing environmental conditions. The lab of Whitehead Member David Sabatini has identified a family of proteins that negatively regulate the branch upstream of mTORC1 that senses amino acids, the building blocks of proteins. The mTORC1 pathway is known to be deregulated in a variety of diseases, including diabetes, epilepsy, and cancer.
National Institutes of Health, Department of Defense

Contact: Nicole Giese Rura
Whitehead Institute for Biomedical Research

Public Release: 25-Sep-2014
Cell Reports
Novel compound prevents metastasis of multiple myeloma in mouse studies
Dana-Farber scientists and colleagues find the compound olaptesed pegol can stop multiple myeloma from spreading in mouse models, potentially leading to a new approach in addressing the challenge of metastasis, one of the deadliest aspects of cancer.
NIH/National Cancer Institue

Contact: Teresa M Herbert
Dana-Farber Cancer Institute

Public Release: 25-Sep-2014
Molecular Cell
Super enhancers in the inflamed endothelium
A study led by researchers at Brigham and Women's Hospital and Dana-Farber Cancer Institute is the first to demonstrate that BET bromodomain-containing proteins help execute this global inflammatory program in the endothelium while BET bromodomain inhibition can significantly decrease atherosclerosis in vivo.
National Institutes of Health

Contact: Marjorie Montemayor-Quellenberg
Brigham and Women's Hospital

Public Release: 24-Sep-2014
Proceedings of the National Academy of Sciences
First mouse model for ALS dementia
The first animal model for ALS dementia, a form of ALS that also damages the brain, has been developed by Northwestern Medicine scientists. The advance will allow researchers to directly see the brains of living mice, under anesthesia, at the microscopic level. This will accelerate drug testing by allowing direct monitoring of test drugs in real time to determine if they work.
National Institutes of Health

Contact: marla Paul
Northwestern University

Public Release: 24-Sep-2014
Better information about prenatal testing leads to fewer tests
A clinical trial led by UC San Francisco has found that when pregnant women are educated about their choices on prenatal genetic testing, the number of tests actually drops, even when the tests are offered with no out-of-pocket costs.
National Institutes of Health, March of Dimes Foundation

Contact: Elizabeth Fernandez
University of California - San Francisco

Public Release: 24-Sep-2014
Cognitive and Behavioral Neurology
Alzheimer's patients can still feel the emotion long after the memories have vanished
A new University of Iowa study further supports an inescapable message: caregivers have a profound influence -- good or bad -- on the emotional state of individuals with Alzheimer's disease. Patients may not remember a recent visit by a loved one or having been neglected by staff at a nursing home, but those actions can have a lasting impact on how they feel.
NIH/National Institute of Neurological Disorders and Stroke, National Science Foundation Graduate Research Fellowship, Kiwanis International

Contact: John Riehl
University of Iowa Health Care

Public Release: 24-Sep-2014
Journal of Clinical Oncology
Good news for young patients with a leukemia subtype associated with a poor prognosis
St. Jude Children's Research Hospital investigators found that adjusting treatment based on early response to chemotherapy made a life-saving difference to young patients with an acute lymphoblastic leukemia subtype associated with a poor outcome.
NIH/National Cancer Institute, NAtional Institutes of Health, National Health & Medical Research Council, Australia, Leukemia & Lymphoma Society, Alex's Lemonade Stand Foundation, Stand Up to Cancer, ALSAC

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 24-Sep-2014
UTHealth researchers to assess asthma risk in health care workers
Researchers at The University of Texas Health Science Center at Houston School of Public Health have been awarded a four-year, $1.3 million grant by the Centers for Disease Control and Prevention and the National Institute for Occupational Safety and Health to study how the risk of asthma has changed for health care workers in Texas over the last 10 years.
Centers for Disease Control and Prevention, NIH/National Institute for Occupational Safety and Health

Contact: Hannah Rhodes
University of Texas Health Science Center at Houston

Public Release: 24-Sep-2014
Pitt drug discovery researchers receive $5.8 million federal grant to build 3-D liver model
Researchers at the University of Pittsburgh School of Medicine have been selected by the National Institutes of Health to develop a microfluidic, 3-D human liver model for drug efficacy and toxicity testing as part of the organization's Tissue Chip for Drug Screening program.
National Institutes of Health

Contact: Anita Srikameswaran
University of Pittsburgh Schools of the Health Sciences

Showing releases 3226-3250 out of 3799.

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