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News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3251-3275 out of 3524.

<< < 126 | 127 | 128 | 129 | 130 | 131 | 132 | 133 | 134 | 135 > >>

Public Release: 25-Nov-2013
Journal of School Violence
Study finds 1 in 10 high school students hurt by dating partners
One in 10 high school youth in the US reports having been hit or physically hurt by a dating partner in the past year, according to a new study led by a Boston University School of Public Health researcher.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Emily Rothman
Boston University Medical Center

Public Release: 25-Nov-2013
Researchers use nanoscale 'patches' to sensitize targeted cell receptors
Researchers have developed nanoscale "patches" that can be used to sensitize targeted cell receptors, making them more responsive to signals that control cell activity. The finding holds promise for promoting healing and facilitating tissue engineering research.
National Science Foundation, NIH/National Institute of Biomedical Imaging and Bioengineering

Contact: Matt Shipman
North Carolina State University

Public Release: 25-Nov-2013
JAMA Pediatrics
UTMB researchers find ear infections down, thanks to vaccine
Researchers from the University of Texas Medical Branch at Galveston have discovered that, during recent years, several interventions have been introduced aiming to decrease the otitis media burden -- and they've been successful. The researchers found there was a downward trend in visits from 2004 to 2011, with a significant drop in children younger than 2 years that coincided with the advent of the 13-valent vaccine, or PCV-13, in 2010.
National Institutes of Health

Contact: Kristen Hensley
University of Texas Medical Branch at Galveston

Public Release: 25-Nov-2013
Journal of Biological Chemistry
Study shows marijuana's potential for treating autoimmune disorders
A new study from researchers at the University of South Carolina provides evidence that THC (tetrahydrocannabinol), a principal ingredient in marijuana, may be beneficial in treating those with autoimmune disorders. The study is the first to explore how tiny, yet powerful molecules called microRNAs are influenced by THC. The ability to alter microRNA expression could hold the key to successful treatments for a whole host of autoimmune diseases, including arthritis and multiple sclerosis.
National Institutes of Health, VA Merit Award

Contact: Jeff Stensland
University of South Carolina

Public Release: 25-Nov-2013
Developmental Cell
Dysfunctional mitochondria may underlie resistance to radiation therapy
The resistance of some cancers to the cell-killing effects of radiation therapy may be due to abnormalities in the mitochondria -- the cellular structures responsible for generating energy, according to an international team of researchers. Their findings are published in the Nov. 25 issue of Developmental Cell.
National Institutes of Health, Leukemia & Lymphoma Society, Natural Sciences and Engineering Research Council of Canada, Spanish Ministry

Contact: Sharon Parmet
University of Illinois at Chicago

Public Release: 25-Nov-2013
Proceedings of the National Academy of Sciences
Using microRNA fit to a T (cell)
Researchers at the University of California, San Diego School of Medicine have successfully targeted T lymphocytes -- which play a central role in the body's immune response -- with another type of white blood cell engineered to synthesize and deliver bits of non-coding RNA or microRNA.
National Institutes of Health

Contact: Scott LaFee
University of California - San Diego

Public Release: 25-Nov-2013
JAMA Neurology
Brain imaging differences in infants at genetic risk for Alzheimer's
Researchers at Brown University and Banner Alzheimer's Institute have found that infants who carry a gene associated with an increased risk for Alzheimer's disease tend to have differences in brain development compared to infants who do not carry the gene. The findings do not mean that these infants will get Alzheimer's, but they may be a step toward understanding how this gene confers risk much later in life.
NIH/National Institute of Mental Health, NIH/National Institute on Aging

Contact: Kevin Stacey
Brown University

Public Release: 25-Nov-2013
Journal of Clinical Investigation
Breaking the brain clock predisposes nerve cells to neurodegeneration
As we age, our body rhythms lose time before they finally stop. Breaking the body clock by genetically disrupting a core clock gene, Bmal1, in mice has long been known to accelerate aging, causing arthritis, hair loss, cataracts, and premature death. New research now reveals that the nerve cells of these mice with broken clocks show signs of deterioration before the externally visible signs of aging are apparent, raising the possibility of novel approaches to staving off or delaying neurodegeneration.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Heart, Lung, and Blood Institute

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 25-Nov-2013
Journal of Clinical Oncology
Nurse navigators help cancer patients cope early in care
When Group Health patients received support from a nurse navigator, or advocate, soon after a cancer diagnosis, they had better experiences and fewer problems with their care -- particularly in health information, care coordination, and psychological and social care -- according to a randomized controlled trial in the Journal of Clinical Oncology.
NIH/National Cancer Institute

Contact: Rebecca Hughes
Group Health Research Institute

Public Release: 25-Nov-2013
Journal of General Physiology
Controlling our circadian rhythms
Most people have experienced the effects of circadian-rhythm disruption, after traveling across time zones or adjusting to a new schedule. To have any hope of modulating our biological "clocks," we need to first understand the physiology at play. A new study in the Journal of General Physiology helps explain some of the biophysical processes underlying regulation of circadian rhythms.
National Institutes of Health, National Science Foundation, American Physiological Society

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 25-Nov-2013
Journal of Clinical Investigation
Identification of a genetic mutation associated with steroid-resistant nephritic syndrome
In this issue of the Journal of Clinical Investigation, Friedhelm Hildebrandt and colleagues at Boston Children's Hospital identified mutations in gene encoding the aarF domain containing kinase 4 (ADCK4) in 15 individuals with steroid-resistant nephritic syndrome from eight different families.
National Institutes of Health, Kidney Foundation of Canada and Nephcure Canada, National Research Foundation

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 25-Nov-2013
Journal of Clinical Investigation
Balancing T cell populations
In this issue of the Journal of Clinical Investigation, Yun-Cai Lu and colleagues at the La Jolla Institute for Allergy and Immunology investigated the role of the mTOR regulator tuberous sclerosis 1 in maintaining immune homeostasis.
NIH/National Institute of Allergy and Infectious Diseases, National Research Foundation of Korea

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 25-Nov-2013
Journal of Clinical Investigation
Identifying targets of autoantibodies
In this issue of the Journal of Clinical Investigation, Jordan Price and colleagues at Stanford University developed a microarray to identify cytokines, chemokines, and other circulating proteins as potential targets of the autoantibodies produced by SLE patients.
National Science Foundation, National Institutes of Health, Canadian Institutes of Health, National Organization for Rare Disorders

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 25-Nov-2013
Journal of Clinical Investigation
Circadian clock proteins maintain neuronal cell function
In this issue of the Journal of Clinical Investigation, Erik Musiek and colleagues at Washington University School of Medicine asked whether BMAL1 and the rest of the core clock contribute to the maintenance of healthy neurons.
National Institutes of Health, Ellison Medical Foundation, American Academy of Neurology

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 24-Nov-2013
Meat, egg and dairy nutrient essential for brain development
"The cells of the body can do without it because they use asparagine provided through diet. Asparagine, however, is not well transported to the brain via the blood-brain barrier," said senior co-author of the study Dr. Jacques Michaud, who found that brain cells depend on the local synthesis of asparagine to function properly.
Fonds de recherche du Québec -- Santé, Canadian Institutes of Health Research, National Institutes of Health, and others

Contact: William Raillant-Clark
University of Montreal

Public Release: 24-Nov-2013
Nature Immunology
Study identifies protein essential for immune recognition, response to viral infection
A Massachusetts General Hospital-led research team has identified an immune cell protein that is critical to setting off the body's initial response against viral infection. They found that a protein called GEF-H1 is essential to the ability of macrophages -- major contributors to the innate immune system -- to respond to viral infections like influenza.
National Institutes of Health

Contact: Sue McGreevey
Massachusetts General Hospital

Public Release: 24-Nov-2013
How living cells solved a needle in a haystack problem to produce electrical signals
Scientists have figured out how cells do the improbable: pick the charged calcium ions out of vast sodium sea to generate electrical signals. The speed and accuracy of this selection is crucial to the beating of the heart and the flow of nerve impulses in the brain. The finding is likely to assist the development of new drugs, such as safer medications for chronic pain.
National Insittutes of Health, NIH/National Institute of Neurological Disorders and Stroke, NIH/National Heart, Lung, and Blood Institute, Howard Hughes Medical Institute

Contact: Leila Gray
University of Washington

Public Release: 22-Nov-2013
Nature Immunology
Paths not taken: Notch signaling pathway keeps immature T cells on the right track
One protein called Notch, which has well-known roles in the development of multiple tissues, plays an essential role in triggering T-cell development. Notch signaling induces expression of genes that promote the maturation of T cells and discourage alternative cell fates. Deficiency of the Notch target gene Hes1 in blood stem cells results in extremely low T-cell numbers, and could shed light on how normal cells are transformed in the context of cancer.
NIH/National Institute of Allergy and Infectious Disease, NIH/National Cancer Institute, NIH/National Institute of General Medical Sciences

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 22-Nov-2013
American Journal of Hematology
Study finds link between allergies and increased risk of blood cancers in women
A team of scientists looking into the interplay of the immune system and cancer have found a link between a history of airborne allergies -- in particular to plants, grass and trees -- with risk of blood cancers in women.
NIH/National Cancer Institute

Contact: Kristen Woodward
Fred Hutchinson Cancer Research Center

Public Release: 22-Nov-2013
Journal of American College of Surgeons
Extent of obesity not strongest factor for patients when choosing weight loss operation
A new study investigating why obese patients choose one type of weight loss operation over another reveals that the main factors influencing decision making are whether patients have type 2 diabetes, how much weight they want to lose, and their tolerance for surgical risk to achieve their ideal weight.
National Institutes of Health, NIH/Midcareer Mentorship Award

Contact: Sally Garneski
American College of Surgeons

Public Release: 22-Nov-2013
UT Dallas professor wins $2.3 million NIH award
Dr. Robert Gregg, an assistant professor of mechanical engineering and bioengineering at UT Dallas, received the award based on his creative, innovative and potentially impactful work to improve prosthetic limbs and orthotic devices.
National Institutes of Health

Contact: LaKisha Ladson
University of Texas at Dallas

Public Release: 22-Nov-2013
Genome Biology
Epigenetic changes may explain chronic kidney disease
Researchers found, in a genome-wide survey, significant differences in the pattern of chemical modifications on DNA that affect gene expression in kidney cells from patients with chronic kidney disease versus healthy controls. This is the first study to show that changes in these modifications -- the cornerstone of the field of epigenetics -- might explain chronic kidney disease.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 22-Nov-2013
Cancer Epidemiology, Biomarkers & Prevention
Sugar-sweetened beverage consumption increases endometrial cancer risk
Postmenopausal women who consumed sugar-sweetened beverages were more likely to develop the most common type of endometrial cancer compared with women who did not drink sugar-sweetened beverages, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
NIH/National Cancer Institute

Contact: Jeremy Moore
American Association for Cancer Research

Public Release: 21-Nov-2013
UCSF scientist wins $89 million grant to study anal cancer in HIV-infected people
A UC San Francisco investigator has won an eight-year grant from the National Cancer Institute for a major investigation into anal cancer, a debilitating and sometimes fatal disease largely concentrated among people with HIV.
NIH/National Cancer Institute

Contact: Elizabeth Fernandez
University of California - San Francisco

Public Release: 21-Nov-2013
Psychology of Addictive Behaviors
Heavy drinking is bad for marriage if 1 spouse drinks, but not both
Do drinking and marriage mix? That depends on who's doing the drinking -- and how much -- according to a recent study by the University at Buffalo Research Institute on Addictions.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Cathy Wilde
University at Buffalo

Showing releases 3251-3275 out of 3524.

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