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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3251-3275 out of 3531.

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Public Release: 7-Jan-2014
Journal of Neuroscience
Unique protein interaction may drive most common genetic cause of Parkinson's disease
Scientists at the Gladstone Institutes have discovered how the interplay between two proteins in the brain fuels the degradation and death of the class of brain cells, or neurons, that leads to Parkinson's disease. These findings, which stand in stark contrast to conventional wisdom, lay much-needed groundwork for developing treatments that target the disease's elusive underlying mechanisms.
National Institutes of Health, Hellman Family Foundation, DeClerg Family, California Institute for Regenerative Medicine

Contact: Anne Holden
Gladstone Institutes

Public Release: 7-Jan-2014
Combination therapy does not improve ability to quit smoking after 1 year
Among cigarette smokers, the combined use of the smoking cessation medications varenicline and bupropion, compared with varenicline alone, resulted in better rates of smoking abstinence at 12 weeks, but rates were similar after one year, according to a study in the Jan. 8 issue of JAMA.
National Institutes of Health

Contact: Kelley Luckstein
The JAMA Network Journals

Public Release: 7-Jan-2014
Adults with mental illness have lower rate of decline in smoking
In recent years, the decline in smoking among individuals with mental illness was significantly less than among those without mental illness, although the rates of quitting smoking were greater among those receiving mental health treatment, according to a study in the Jan. 8 issue of JAMA.
NIH/National Institute of Mental Health

Contact: David Cecere
The JAMA Network Journals

Public Release: 7-Jan-2014
BPA increases risk of cancer in human prostate tissue
Fetal exposure to a commonly used plasticizer found in products such as water bottles, soup can liners and paper receipts, can increase the risk for prostate cancer later in life, according to a study from the University of Illinois at Chicago published Jan. 7 online in the journal Endocrinology.
National Institutes of Health

Contact: Sharon Parmet
University of Illinois at Chicago

Public Release: 7-Jan-2014
Long-term varenicline treatment supports tobacco abstinence in people with mental illness
Extended treatment with the smoking cessation drug varenicline significantly improved the ability of individuals with serious mental illness to maintain abstinence from tobacco after a standard 12-week course of treatment.
NIH/National Institute of Drug Abuse

Contact: Kristen Chadwick
Massachusetts General Hospital

Public Release: 7-Jan-2014
American Journal of Preventive Medicine
'Traffic light' food labels, positioning of healthy items produce lasting choice changes
The use of color-coded "traffic light" food labels and changes in the way popular items are displayed appear to have produced a long-term increase in the choice of more healthful food items among customers in a large hospital cafeteria.
Robert Wood Johnson Foundation, Donoghue Foundation, NIH/National Heart, Lung and Blood Institute

Contact: Cassandra Aviles
Massachusetts General Hospital

Public Release: 7-Jan-2014
50 years of tobacco control significantly extended lives of 8 million Americans
50 years ago, the US Surgeon General issued a report, which outlined, for the first time, the effects of smoking on health. It along with tobacco control efforts that followed are responsible for adding nearly 20 years of life to eight million people -- people like John Hilburn. The 67-year-old former smoker gave up his 2-pack-a-day 20-year habit 30 years ago because of the warning label and cost.
NIH/National Cancer Institute

Contact: Karen Teber
Georgetown University Medical Center

Public Release: 7-Jan-2014
PLOS Medicine
Sugar-sweetened beverage tax could reduce obesity and Type 2 diabetes in India
A sugar-sweetened beverage tax could help mitigate the rise in obesity and Type 2 diabetes rates in India among both urban and rural populations, according to a study published this week in PLOS Medicine.
NIH/National Institute on Aging, International Development Research Center, Wellcome Trust

Contact: Fiona Godwin

Public Release: 6-Jan-2014
Medical Care
Personal health record associated with improved medication adherence
Patients with diabetes who used an online patient portal to refill medications increased their medication adherence and improved their cholesterol levels, according to a new study in the journal Medical Care.
National Institutes of Health

Contact: Cyrus Hedayati
Kaiser Permanente

Public Release: 6-Jan-2014
Discovery spotlights key role of mystery RNA modification in cells
Researchers had known for several decades that a certain chemical modification exists on messenger ribonucleic acid, which is essential to the flow of genetic information. But only recently did experiments at the University of Chicago show that one major function of this modification governs the longevity and decay of RNA, a process critical to the development of healthy cells.
National Institutes of Health, National Science Foundation

Contact: Steve Koppes
University of Chicago

Public Release: 6-Jan-2014
Clinical Cancer Research
UW-Madison researchers link protein with breast cancer's spread to the brain
A cancer research team at the University of Wisconsin-Madison has identified a protein that may be a major culprit when breast cancer metastasizes to the brain.
Breast Cancer Research Foundation, National Institutes of Health, Susan G. Komen, and others

Contact: Lisa Brunette
University of Wisconsin-Madison

Public Release: 6-Jan-2014
Costs for complications from cancer surgical care extremely high
Although complications from surgical care for cancer patients may seem infrequent, the costs associated with such outcomes are extremely high, according to researchers from Rice University's Baker Institute for Public Policy and the University of Texas MD Anderson Cancer Center. Their findings were reported in the Dec. 30 online edition of the journal Cancer.
NIH/National Cancer Institute, Cancer Prevention and Research Institute of Texas

Contact: Jeff Falk
Rice University

Public Release: 6-Jan-2014
Proceedings of the National Academy of Sciences
No 'brakes' -- Study finds mechanism for increased activity of oncogene in certain cancers
The increased activation of a key oncogene in head and neck cancers could be the result of mutation and dysfunction of regulatory proteins that are supposed to keep the gene, which has the potential to cause cancer, in check, according to a new study led by researchers at the University of Pittsburgh School of Medicine published this week in the early online version of the Proceedings of the National Academy of Sciences.
National Institutes of Health, and others

Contact: Anita Srikameswaran
University of Pittsburgh Schools of the Health Sciences

Public Release: 6-Jan-2014
Proceedings of the National Academy of Sciences
Tiny proteins have outsized influence on nerve health
Mutations in small proteins that help convey electrical signals throughout the body may have a surprisingly large effect on health, according to results of a new Johns Hopkins study using spider, scorpion and sea anemone venom.
NIH/National Institute of Neurological Disorders and Stroke, Human Frontier Science Program Grant

Contact: Vanessa McMains
Johns Hopkins Medicine

Public Release: 6-Jan-2014
Journal of General Internal Medicine
BIDMC researcher looks at race and bariatric surgery
The nearly 100,000 Americans who undergo bariatric surgery each year represent only a small fraction of people who are medically eligible for the procedure. Among those who have surgery, Caucasian-Americans are twice as likely as African-Americans to have weight loss surgery. On the surface, the data appear to signal racial disparity, but when researchers at Beth Israel Deaconess Medical Center dug deeper to ask why this variation exists, the answer was more complicated.
National Institutes of Health

Contact: Kelly Lawman
Beth Israel Deaconess Medical Center

Public Release: 6-Jan-2014
Frontiers in Neuroscience
Stimulating brain cells stops binge drinking, animal study finds
Researchers at the University at Buffalo have found a way to change alcohol drinking behavior in rodents, using the emerging technique of optogenetics, which uses light to stimulate neurons.
National Institutes of Health

Contact: Ellen Goldbaum
University at Buffalo

Public Release: 6-Jan-2014
Imaging technology to improve survival of ischemic disease patients
Researchers at Case Western Reserve University and University Hospitals Case Medical Center received a $1.7 million NIH grant to transform imaging inside coronary arteries. The technology would enable doctors to identify vulnerable plaques and optimize stent placements in ischemic heart disease patients.
National Institutes of Health

Contact: Kevin Mayhood
Case Western Reserve University

Public Release: 6-Jan-2014
Suicide risk doesn't differ in children taking 2 types of commonly prescribed antidepressants
A Vanderbilt University Medical Center study released today shows there is no evidence that the risk of suicide differs with two commonly prescribed antidepressants prescribed to children and adolescents.
NIH/National Institute of Mental Health

Contact: Craig Boerner
Vanderbilt University Medical Center

Public Release: 6-Jan-2014
Proceedings of the National Academy of Sciences
Piggy-backing proteins ride white blood cells to wipe out metastasizing cancer
Cornell biomedical engineers have discovered a new way to destroy metastasizing cancer cells traveling through the bloodstream -- lethal invaders that are linked to almost all cancer deaths -- by hitching cancer-killing proteins along for a ride on life-saving white blood cells.
NIH/National Cancer Institute

Contact: Melissa Osgood
Cornell University

Public Release: 6-Jan-2014
Proceedings of the National Academy of Sciences
Biomaterials get stem cells to commit to a bony future
With the help of biomimetic matrices, a research team led by bioengineers at the University of California, San Diego has discovered exactly how calcium phosphate can coax stem cells to become bone-building cells. This work is published in the Proceedings of the National Academy of Sciences the week of Jan. 6, 2014.
National Institutes of Health, Taiwan National Science Council

Contact: Daniel Kane
University of California - San Diego

Public Release: 5-Jan-2014
Yeast's lifestyle couples mating with meiosis
Mating and meiosis -- the specialized cell division that reduces the number of chromosomes in a cell -- are related, but in most yeasts they are regulated separately. Not so in Candida lusitaniae, where the two programs work in unison, according to a new study in Nature. Comparison with other species suggests that this fusion may support C. lusitaniae's "haploid lifestyle" of maintaining only one set of chromosomes in each cell.
National Science Foundation, National Institutes of Health, Burroughs Wellcome

Contact: David Orenstein
Brown University

Public Release: 3-Jan-2014
Loss of function of a single gene linked to diabetes in mice
Researchers from the University of Illinois at Chicago College of Medicine have found that dysfunction in a single gene in mice causes fasting hyperglycemia, one of the major symptoms of Type 2 diabetes. Their findings were reported online in the journal Diabetes.
National Institutes of Health

Contact: Sharon Parmet
University of Illinois at Chicago

Public Release: 3-Jan-2014
Parkinson's patients utilization of deep brain stimulation treatment reduced in demographic groups
Among Parkinson's disease patients, female, black, and Asian patients are substantially less likely to receive proven deep brain stimulation (DBS) surgery to improve tremors and motor symptoms, according to a new report by a Perelman School of Medicine at the University of Pennsylvania researcher who identified considerable disparities among Medicare recipients receiving DBS for Parkinson's disease.
National Institutes of Health, St. Louis Chapter-American Parkinson Disease Association

Contact: Kim Menard
University of Pennsylvania School of Medicine

Public Release: 2-Jan-2014
American Journal of Medicine
Patch outperforms Holter for prolonged heart rhythm tracking
Research by the Scripps Translational Science Institute has found that a small adhesive wireless device worn on the chest for up to two weeks does a better job detecting abnormal and potentially dangerous heart rhythms than the Holter monitor, which is typically used for 24 hours and has been the standard of care for more than 50 years.
National Institutes of Health, iRhythm Technologies

Contact: Keith Darce
Scripps Health

Public Release: 2-Jan-2014
Genetically identical bacteria can behave in radically different ways
When a bacterial cell divides into two daughter cells there can be an uneven distribution of certain survival mechanisms. The resulting cells can behave differently from each other, depending on which parts they received in the split. This is another way that cells within a population can diversify and enhance the odds that some members of a population of bacteria can avoid threats, such as antibiotics.
NIH/National Institute of Allergy and Infectious Diseases, National Institutes of Health, National Science Foundation

Contact: Leila Gray
University of Washington

Showing releases 3251-3275 out of 3531.

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