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Key: Meeting M      Journal J      Funder F

Showing releases 3251-3275 out of 3685.

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Public Release: 19-Jan-2015
European Heart Journal
Drinking moderate amounts of alcohol is linked to reduced risk of heart failure
Evidence already exists for the beneficial effects of drinking moderate amounts of alcohol on the risk of developing a number of heart conditions; however, the role it plays in the risk of developing heart failure has been under-researched with conflicting results. Now, a large study of nearly 15,000 men and women, published in the European Heart Journal, shows that drinking up to seven drinks a week in early to middle age is associated with a lower risk of developing heart failure.
NIH/National Heart, Lung, and Blood Institute, Ellison Foundation, Portuguese Foundation for Science and Technology

Contact: Emma Mason
European Society of Cardiology

Public Release: 19-Jan-2015
Proceedings of the National Academy of Sciences
New cellular pathway triggering allergic asthma response identified
Researchers at the University of California, San Diego School of Medicine, with collaborators in Korea and Scotland, have identified a novel signaling pathway critical to the immune response of cells associated with the initiation of allergic asthma. The discovery, they say, could point the way to new therapies that suppress the inflammatory allergic response, offering potential relief to millions of Americans with the chronic lung condition and potentially other allergic diseases.
National Institutes of Health, Crohn's and Colitis Foundation of America, US Department of Veterans Affairs

Contact: Scott LaFee
University of California - San Diego

Public Release: 16-Jan-2015
Proceedings of the National Academy of Sciences
New genetic clues found in fragile X syndrome
Scientists at Washington University School of Medicine in St. Louis have gained new insight into fragile X syndrome -- the most common cause of inherited intellectual disability -- by studying the case of a person without the disorder, but with two of its classic symptoms.
National Institutes of Health, The FRAXA Foundation

Contact: Julia Evangelou Strait
Washington University School of Medicine

Public Release: 16-Jan-2015
Nature Communications
Rare mutations do not explain 'missing heritability' in asthma
Rare genetic mutations have been thought to explain missing heritability, but it appears they are unlikely to play a major role. Analyzing the coding regions of genomes of more than 11,000 individuals, scientists from the University of Chicago identified mutations in just three genes that were associated with asthma risk. Each was associated with risk in specific ethnicities, suggesting gaps in the current understanding of asthma genetics.
National Institutes of Health, American Asthma Foundation, The Hastings Foundation, Fund for Henry Ford Hospital

Contact: Kevin Jiang
University of Chicago Medical Center

Public Release: 16-Jan-2015
New trick found for how cells stay organized
Organization is key to an efficient workplace, and cells are no exception to this rule. New evidence from Johns Hopkins researchers suggests that, in addition to membranes, cells have another way to keep their contents and activities separate: with ribbons of spinning proteins.
NIH/National Institute of Child Health and Human Development, Howard Hughes Medical Institute

Contact: Catherine Kolf
Johns Hopkins Medicine

Public Release: 16-Jan-2015
BPA exposure affects heart health of males and females differently in mouse models
Heart function and blood pressure in mice exposed to bisphenol A, BPA, from birth though young adulthood are affected differently in males and females, with females at greater risk of damage from stress, a study from a University of Cincinnati researcher has found.
NIH/National Institute of Environmental Health Sciences

Contact: Cedric Ricks
University of Cincinnati Academic Health Center

Public Release: 16-Jan-2015
Alcoholism: Clinical & Experimental Research
Adolescents who sleep poorly and insufficiently may develop alcohol and drug problems
Sleep difficulties and insufficient sleep are common among American youth. New research has found that sleep difficulties can predict specific substance-related problems. Problems include binge drinking, driving under the influence of alcohol, and risky sexual behavior.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Maria M. Wong, Ph.D.
Alcoholism: Clinical & Experimental Research

Public Release: 16-Jan-2015
Alcoholism: Clinical & Experimental Research
Genes and environment contribute to personal and peer drinking during adolescence and beyond
Alcohol use typically begins during adolescence, in social settings, and is influenced by peer drinking. New findings indicate that both genetic and environmental factors contribute to the correlation between one's own drinking and peer drinking. The influence of genetic factors increases as an individual moves from adolescence into adulthood.
National Institutes of Health, Carman Trust, W. Keck Foundation, John Templeton Foundation, Robert Wood Johnson Foundation

Contact: Alexis C. Edwards, Ph.D.
Alcoholism: Clinical & Experimental Research

Public Release: 16-Jan-2015
Alcoholism: Clinical & Experimental Research
Pre-sleep drinking disrupts sleep
For individuals who drink before sleeping, alcohol initially acts as a sedative -- marked by the delta frequency electroencephalogram (EEG) activity of Slow Wave Sleep (SWS) -- but is later associated with sleep disruption. A study of the effects of alcohol on sleep EEG power spectra in college students has found that pre-sleep drinking not only causes an initial increase in SWS-related delta power but also causes an increase in frontal alpha power, which is thought to reflect disturbed sleep.
Australasian Sleep Association, National Health and Medical Research Council, National Institutes of Health

Contact: Christian L. Nicholas, Ph.D.
Alcoholism: Clinical & Experimental Research

Public Release: 15-Jan-2015
Investigative Ophthalmology and Visual Science
Scientists discover gene tied to profound vision loss
An exhaustive hereditary analysis of a large Louisiana family with vision issues has uncovered a new gene tied to an incurable eye disorder called retinitis pigmentosa, according to an examination led by scientists at The University of Texas Health Science Center at Houston. It is a family of eye diseases that affects more than 200,000 people in the United States and millions worldwide.
Hermann Eye Fund, National Institutes of Health, National Genome Research Institute, Foundation Fighting Blindness

University of Texas Health Science Center at Houston

Public Release: 15-Jan-2015
Circulation: Cardiovascular Quality and Outcomes
When used effectively, discharge summaries reduce hospital readmissions
For heart failure patients making the transition from hospital to home, a discharge summary that gets to their primary doctors quickly and contains detailed and useful information can mean the difference between recovering quickly or returning to the hospital, according to two studies from Yale School of Medicine researchers.
NIH/National Heart, Lung and Blood Institute, NIH/National Institute on Aging, American Federation for Aging, Yale University

Contact: Karen N. Peart
Yale University

Public Release: 15-Jan-2015
Bone stem cells shown to regenerate bone and cartilage in adult mice
A stem cell capable of regenerating both bone and cartilage has been identified in bone marrow of mice.
National Institutes of Health

Contact: Karin Eskenazi
Columbia University Medical Center

Public Release: 15-Jan-2015
MIT team enlarges brain samples, making them easier to image
Massachusetts Institute of Technology researchers have discovered a method that enlarges tissue samples by embedding them in a polymer that swells when water is added.
National Institutes of Health, New York Stem Cell Foundation, Jeremy and Joyce Wertheimer, National Science Foundation, Fannie and John Hertz Foundation

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 15-Jan-2015
Nature Immunology
Tumor suppressor protein plays key role in maintaining immune balance
St. Jude Children's Research Hospital scientists have discovered that a protein widely known for suppressing tumor formation also helps prevent autoimmune diseases and other problems by putting the brakes on the immune response. The research was published recently online ahead of print in the scientific journal Nature Immunology.
National Institutes of Health, American Cancer Society, Crohn's & Colitis Foundation of America, Arthritis Foundation, ALSAC

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 15-Jan-2015
Cellular and Molecular Gastroenterology and Hepatology
Research offers novel insight into Hirschsprung's disease
Defects in the protein Sox10, a transcription factor that regulates gene expression, may play a role in the development of post-operative GI dysfunction in Hirschsprung's disease patients, according to new research published in Cellular and Molecular Gastroenterology and Hepatology, the new basic science journal of the American Gastroenterological Association.
March of Dimes, National Intsitutes of Health, NIH/National Institute of General Medical Sciences to the Vanderbilt Medical-Scientist Training Program.

Contact: Rachel Steigerwald
American Gastroenterological Association

Public Release: 15-Jan-2015
Cellular and Molecular Gastroenterology and Hepatology
New approach to preventing fibrosing strictures in IBD
A natural protein made by immune cells may limit fibrosis and scarring in colitis, according to research published in the inaugural issue of Cellular and Molecular Gastroenterology and Hepatology, the new basic science journal of the American Gastroenterological Association.
National Institutes of Health, US Public Health Service, UCLA-CURE Center, Crohn's and Colitis Foundation of America, The Blinder Research Foundation for Crohn's Disease, and others

Contact: Rachel Steigerwald
American Gastroenterological Association

Public Release: 15-Jan-2015
Genes and Development
What makes pancreatic cancer so aggressive? New study sheds light
New research from the University of Michigan Comprehensive Cancer Center helps explain why pancreatic cancer is so lethal, with fewer than one-third of patients surviving even early stage disease.
NIH/National Cancer Institute, Rogel Family Pancreatic Cancer Research Fund

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 15-Jan-2015
When heavy metals go off-kilter: Study in C. elegans shows excess iron promotes aging
It's been long known that some metals, including iron, accumulate in tissues during aging and that toxic levels of iron have been linked to neurologic diseases, including Parkinson's. Common belief has held that iron accumulation happens as a result of the aging process. But research in C. elegans shows that iron accumulation itself may also be a significant contributor to the aging process causing dysfunction and malfolding of proteins already implicated in the aging process.
Larry L. Hillblom Foundation, Glenn Foundation for Medical Research, National Institutes of Health

Contact: Kris Rebillot
Buck Institute for Research on Aging

Public Release: 15-Jan-2015
Vaccine-induced CD4 T cells have adverse effect in a mouse model of infection
New findings demonstrate that vaccine-elicted CD4 T cells lead to overwhelming inflammatory response in mouse model of chronic infection.
National Institutes of Health, Bill & Melinda Gates Foundation, Swiss National Science Foundation, European Research Council, Ragon Institute of MGH, MIT and Harvard, NIH/National Institute of Allergy and Infectious Diseases Intramural Research Program

Contact: Bonnie Prescott
Beth Israel Deaconess Medical Center

Public Release: 15-Jan-2015
Science Signaling
Moffitt researchers develop novel approach to visualize, measure protein complexes in tumors
Cancer diagnosis and treatment decisions are often hampered by a lack of knowledge of the biological processes occurring within the tumor. Moffitt Cancer Center researchers have developed a new approach to analyze these processes with a technique called proximity ligation assays. PLA allows specific protein complexes to be visualized and measured in cancer specimens. This may aid in patient treatment decisions in the future.
NIH/National Cancer Institute

Contact: Kim Polacek
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 15-Jan-2015
Journal of Pediatrics
Difficult behavior in young children may point to later problems
It's normal for a very young child to have tantrums and be otherwise disruptive, but researchers have found that if such behavior is prolonged or especially intense, the child may have conduct disorder. A Washington University team, led by senior investigator Joan L. Luby, MD, recommends that children who exhibit these symptoms be referred to mental health professionals for evaluation and possible intervention.
NIH/National Institute of Mental Health

Contact: Jim Dryden
Washington University School of Medicine

Public Release: 15-Jan-2015
Vitamin D protects against colorectal cancer by boosting the immune system
A new study by Dana-Farber Cancer Institute investigators demonstrates that vitamin D can protect some people with colorectal cancer by perking up the immune system's vigilance against tumor cells.
National Institutes of Health, Friends of Dana-Farber Cancer Institute, Bennett Family Fund, Entertainment Industry Foundation, Paula and Russell Agrusa Fund for Colorectal Cancer Research

Contact: Anne Doerr
Dana-Farber Cancer Institute

Public Release: 15-Jan-2015
PLOS Medicine
Increasing reach of treatment for STIs through expedited partner therapy
A public health program in the US State of Washington promoting the use of expedited partner therapy -- the treatment, without medical evaluation, of sex partners of patients diagnosed with a curable sexually transmitted disease -- increased expedited partner therapy use and may have reduced rates of sexually transmitted disease in the population, though the intervention's effectiveness in reducing sexually transmitted disease in the general population requires further confirmation, according to a study published this week in PLOS Medicine.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Maya Sandler

Public Release: 15-Jan-2015
Arthritis & Rheumatology
Lower mortality rates among Asian and Hispanic lupus patients
A new study by researchers from Brigham and Women's Hospital in Boston, Massachusetts reveals that Asian and Hispanic patients with systemic lupus erythematosus (SLE) have lower mortality rates compared to Black, White, or Native Americans with the disease. Findings published in Arthritis & Rheumatology, a journal of the American College of Rheumatology, indicate that the risk for death among White patients is much lower than in Black and Native American SLE patients.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, Fundacion Alfonso Martin Escudero Gran, Lupus Foundation of America Career Development Award

Contact: Dawn Peters

Public Release: 15-Jan-2015
Diabetes Care
Healthy diet associated with lower risk of type 2 diabetes in minority women
Consuming a healthy diet was associated with reduced risk for type 2 diabetes among women in all racial and ethnic groups but conferred an even greater benefit for Asian, Hispanic, and black women, according to a new study by researchers at Harvard T.H. Chan School of Public Health and Brigham and Women's Hospital.
National Institutes of Health

Contact: Marge Dwyer
Harvard T.H. Chan School of Public Health

Showing releases 3251-3275 out of 3685.

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