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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 3251-3275 out of 3461.

<< < 126 | 127 | 128 | 129 | 130 | 131 | 132 | 133 | 134 | 135 > >>

Public Release: 23-Sep-2013
ASTRO's 55th Annual Meeting
Simple, 2-question survery accurately screens cancer patients for depression
Cancer patients can be accurately screened for major depression with a simple two-question survey, according to a study at the American Society for Radiation Oncology's 55th Annual Meeting. The two-question screening test proved to be as accurate as a nine-question test.
National Institutes of Health

Contact: Jim Ritter
jritter@lumc.edu
708-216-2445
Loyola University Health System

Public Release: 23-Sep-2013
Pediatrics
Breastfeeding fraught with early challenges for many first-time mothers
A new study shows that new moms who report early concerns or problems with breastfeeding are nearly 10 times more likely to abandon breastfeeding within two months.
National Institutes of Health

Contact: Jim Feuer
jim.feuer@cchmc.org
513-636-4656
Cincinnati Children's Hospital Medical Center

Public Release: 22-Sep-2013
Nature Chemical Biology
Propofol discovery may aid development of new anesthetics
Researchers at Washington University School of Medicine in St. Louis and Imperial College London are the first to identify the site where the widely used anesthetic drug propofol binds to receptors in the brain to sedate patients during surgery.
Medical Research Council, National Institutes of Health, Austrian Ministry of Science and Research

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine

Public Release: 22-Sep-2013
Nature Chemical Biology
Propofol discovery may help lead to development of new anesthetics
New research on the most commonly used anesthetic drug could help to unravel a long-standing mystery about how it induces a pain-free, sleep-like state. Following years of research, scientists have identified exactly how propofol acts at a molecular level. Having a more detailed picture of exactly how it works in the brain may help scientists to design new versions that reduce the risks involved in surgery. Propofol was linked to the death of Michael Jackson.
Medical Research Council, NIH/National Institute of General Medical Sciences, National Institutes of Health, Austrian Ministry of Science and Research, European Seventh Framework Program

Contact: Simon Levey
s.levey@imperial.ac.uk
44-020-759-46702
Imperial College London

Public Release: 22-Sep-2013
Nature Cell Biology
USC scientists ID protein that regulates cellular trafficking, potential for anti-cancer therapy
USC scientists have identified a new regulator for the intracellular trafficking of proteins between the endoplasmic reticulum and Golgi apparatus, which is a crucial process for maintaining homeostasis and prevention of human disease. The study provides a new avenue to investigate anti-cancer agents that target the regulatory protein UVRAG and/or intracellular trafficking process.
American Cancer Society, National Institutes of Health

Contact: Alison Trinidad
alison.trinidad@usc.edu
323-442-3941
University of Southern California - Health Sciences

Public Release: 22-Sep-2013
Nature Neuroscience
Calming fear during sleep
A fear memory was reduced in people by exposing them to the memory over and over again while they slept. It's the first time that emotional memory has been manipulated during sleep, report scientists. The finding potentially offers a new way to enhance the typical daytime treatment of phobias through exposure therapy by adding a nighttime component. A common treatment for phobias is gradual exposure to the feared object until the fear is extinguished.
National Institutes of Health

Contact: Marla Paul
Marla-Paul@northwestern.edu
312-503-8928
Northwestern University

Public Release: 20-Sep-2013
Experimental Biology and Medicine
Prostacyclin analogs and PDE 5 inhibitors synergistically stimulate ATP release from human RBCs
Prostacyclin (PGI2) and phosphodiesterase 5 (PDE5) inhibitors are vasodilators used in the treatment of pulmonary arterial hypertension (PAH). Although these drugs stimulate vascular dilation directly, erythrocytes also express the PGI2 receptor (IPR) and contain PDE5. We determined that PDE5 inhibitors potentiate IPR-mediated release of the potent vasodilator, adenosine triphosphate from erythrocytes. These results demonstrate a novel synergism between IPR agonists and PDE5 inhibitors that could provide a new rationale for the treatment of PAH.
American Diabetes Association, National Institutes of Health, United Therapeutics

Contact: Stephanie M. Knebel
knebelsm@slu.edu
Society for Experimental Biology and Medicine

Public Release: 20-Sep-2013
Cell Reports
Researchers identify a switch that controls growth of most aggressive brain tumor cells
Researchers at UT Southwestern Medical Center have identified a cellular switch that potentially can be turned off and on to slow down, and eventually inhibit the growth of the most commonly diagnosed and aggressive malignant brain tumor.
National Institutes of Health, NASA, Cancer Prevention and Research Institute of Texas

Contact: Remekca Owens
remekca.owens@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center

Public Release: 20-Sep-2013
Milbank Quarterly
Personality a key factor in health care use
Psychiatrists and psychologists have long understood that an individual's personality can define how he or she views the world around them, reacts to situations, and interacts with others. It now appears that personality traits can be linked to the frequency with which older adults use expensive health care services.
NIH/National Institute on Aging

Contact: Mark Michaud
mark_michaud@urmc.rochester.edu
585-273-4790
University of Rochester Medical Center

Public Release: 20-Sep-2013
Nature Neuroscience
Building the best brain: U-M researchers show how brain cell connections get cemented early in life
When we're born, our brains aren't very organized, but as we grow and learn, things get a bit more stable. How and why does this happen -- and what happens when it doesn't go normally? Researchers have made a major stride in understanding this process, called synapse maturation.
Klingenstein Fund, Mallinckrodt Foundation, March of Dimes Foundation, National Institutes of Health

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 20-Sep-2013
Journal of Immunology
Scripps Research Institute study explores barriers to HIV vaccine response
Researchers at The Scripps Research Institute discovered that an antibody that binds and neutralizes HIV likely also targets the body's own "self" proteins. This finding could complicate the development of HIV vaccines designed to elicit this protective antibody, called 4E10, and others like it, as doing so might be dangerous or inefficient.
National Institutes of Health, International AIDS Vaccine Initiative Neutralizing Antibody Center, Ragon Institute

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 20-Sep-2013
Journal of Pediatrics
Imaging technique detects pediatric liver disease without need for needle biopsy
A new, non-invasive imaging technique, magnetic resonance elastography, can now help physicians accurately detect fibrosis (scarring) in children with chronic liver disease -- a growing problem due in part to increasing obesity rates.
National Institutes of Health

Contact: Jim Feuer
jim.feuer@cchmc.org
513-636-4656
Cincinnati Children's Hospital Medical Center

Public Release: 19-Sep-2013
Journal of Adolescent Health
Higher calorie diets increase weight gain, shorten hospital stays for teens with anorexia
Higher calorie diets produce twice the rate of weight gain compared to the lower calorie diets that currently are recommended for adolescents hospitalized with anorexia nervosa, according to a study by researchers at UCSF Benioff Children's Hospital.
University of California, San Francisco/Clinical and Translational Science Institute, National Institutes of Health

Contact: Juliana Bunim
juliana.bunim@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 19-Sep-2013
UCSF awarded $20 million federal grant on tobacco regulatory science
UC San Francisco will receive a five-year, $20 million grant as part of a first-of-its-kind tobacco science regulatory program by the US Food and Drug Administration and the National Institutes of Health.
US Food and Drug Administration, National Institutes of Health

Contact: Elizabeth Fernandez
elizabeth.fernandez@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 19-Sep-2013
Archives of Environmental Contamination and Toxicology
Mine metals at Maine Superfund site causing widespread contamination
Toxic metals from the only open pit mine in an estuary system in the United States are widespread in nearby sediment, water and fish and may be affecting marine and coastal animals that feed on them beyond the mine site, a new Dartmouth study finds.
NIH/National Institute of Environmental Health Sciences

Contact: John Cramer
john.cramer@dartmouth.edu
603-646-9130
Dartmouth College

Public Release: 19-Sep-2013
Cancer Causes & Control
Moffitt Cancer Center launches prostate cancer study focused on black men
Prostate cancer kills more African-American and black men than any other group. With the lack of cancer research targeting this population in mind, Moffitt has launched a clinical trial using a botanical agent, isoflavones, on African-American and black men with prostate cancer. The trial is aimed at determining the safety, effectiveness and mechanism by which isoflavones can better reduce the risk of prostate cancer in African-American and black men.
US Department of Defense Prostate Cancer Research Program, National Institutes of Health

Contact: Kim Polacek
kim.polacek@moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 19-Sep-2013
Annals of Neurology
Could dog food additive prevent disabling chemotherapy side effect?
Working with cells in test tubes and in mice, researchers at Johns Hopkins have discovered that a chemical commonly used as a dog food preservative may prevent the kind of painful nerve damage found in the hands and feet of four out of five cancer patients taking the chemotherapy drug Taxol.
NIH/National Institute of Neurological Disorders and Stroke, Johns Hopkins Brain Science Institute

Contact: Stephanie Desmon
sdesmon1@jhmi.edu
410-955-8665
Johns Hopkins Medicine

Public Release: 19-Sep-2013
Antimicrobial Agents and Chemotherapy
Disarming HIV with a 'pop'
A team of Drexel University researchers is trying to get one step ahead of the virus with a microbicide they've created that can trick HIV into "popping" itself into oblivion.
National Institutes of Health

Contact: Britt Faulstick
bef29@drexel.edu
215-895-2617
Drexel University

Public Release: 19-Sep-2013
School of public health gets $19 million grant for tobacco research
In what is the largest grant in Georgia State University history, the university's School of Public Health and its partners will receive $19 million over five years from the US Food and Drug Administration and the National Institutes of Health to establish one of 14 Tobacco Centers of Regulatory Science.
US Food and Drug Administration, National Institutes of Health

Contact: Frances Marine
francesmarine@gsu.edu
404-413-1504
Georgia State University

Public Release: 19-Sep-2013
UNC partners with FDA, NIH to create Tobacco Centers of Regulatory Science
The University of North Carolina at Chapel Hill received two separate grants from the US Food and Drug Administration and the National Institutes of Health today as part of an on-going interagency partnership. UNC will house two of 14 Tobacco Centers of Regulatory Science, which are receiving a total of up to $53 million for tobacco-related research in fiscal year 2013.
US Food and Drug Administration, National Institutes of Health

Contact: Tom Hughes
tahughes@unch.unc.edu
919-966-6047
University of North Carolina Health Care

Public Release: 19-Sep-2013
Nature Communications
Researchers tease apart workings of a common gene
Researchers at Weill Cornell Medical College have discovered why a tiny alteration in a brain gene, found in 20 percent of the population, contributes to the risk for anxiety, depression and memory loss.
National Institutes of Health, Human Frontier Science Program

Contact: Sarah Smith
sas2072@med.cornell.edu
646-317-7401
Weill Cornell Medical College

Public Release: 19-Sep-2013
UTHealth awarded $20 million to launch Tobacco Regulatory Science Center
The University of Texas School of Public Health has received $20 million in funding from the United States Food and Drug Administration and the National Institutes of Health today as part of an ongoing interagency partnership.
National Institutes of Health, Food and Drug Administration

Contact: Stephanie Logue
stephanie.d.logue@uth.tmc.edu
713-500-3307
University of Texas Health Science Center at Houston

Public Release: 19-Sep-2013
Cell Reports
Global analysis reveals new insights into the ribosome -- with important implications for disease
In a first-of-its-kind study that broadly examines the composition of the riboproteome, a scientific team led by investigators at Beth Israel Deaconess Medical Center reveals previously unappreciated components of the ribosome, uncovering a large and dynamic structure that, among other things, can be altered in cancer.
National Institutes of Health, German Academy of Sciences Leopoldina

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center

Public Release: 19-Sep-2013
American Journal of Epidemiology
Older adults live longer with a few extra pounds -- if they don't add more
Some overweight older adults don't need to lose weight to extend their lives, but they could risk an earlier death if they pack on more pounds.
NIH/Eunice Kennedy Shriver National Institute for Child Health and Human Development

Contact: Hui Zheng
Zheng.64@sociology.osu.edu
614-688-8348
Ohio State University

Public Release: 19-Sep-2013
Structure
Protein 'motif' crucial to telomerase activity, Wistar researchers say
In an effort to understand and control telomerase activity, researchers at the Wistar Institute have discovered a protein "motif," named TFLY, which is crucial to the function of telomerase. Altering this motif disrupts telomerase function, they found, a fact that they believe will help them in their efforts to identify inhibitors of telomerase with potential cancer therapeutic properties.
NIH/National Institute of General Medical Sciences

Contact: Greg Lester
glester@wistar.org
215-898-3943
The Wistar Institute

Showing releases 3251-3275 out of 3461.

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