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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 3301-3325 out of 3482.

<< < 128 | 129 | 130 | 131 | 132 | 133 | 134 | 135 | 136 | 137 > >>

Public Release: 7-Oct-2013
Journal of Virology
How JC Polyomavirus invades cells
A new study in the Journal of Virology identifies the means by which the JC Polyomavirus enters host cells. It's a particular subset of serotonin receptors.
National Institutes of Health

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 7-Oct-2013
Biological Psychology
How do stress hormones during pregnancy predict adult nicotine addiction?
Adult women whose mothers had increased levels of stress hormones while they were pregnant are at greater risk of becoming addicted to nicotine, according to a new study led by a Miriam Hospital researcher.
National Institutes of Health

Contact: Jessica Collins Grimes
jgrimes2@lifespan.org
Lifespan

Public Release: 7-Oct-2013
Budnik gets EUREKA grant to study communication between nucleus and cytoplasm
University of Massachusetts Medical School Professor and Vice Chair of Neurobiology Vivian Budnik, Ph.D., has received a four-year, $1.3 million EUREKA (Exceptional Unconventional Research Enabling Knowledge Acceleration) grant from the National Institute of Neurological Disorders and Stroke to explore a novel mechanism of communication between the cytoplasm and the nucleus, called nuclear envelope budding, that may lead to new understandings for various tissue dystrophies and aging disorders.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Jim Fessenden
james.fessenden@umassmed.edu
508-856-2000
University of Massachusetts Medical School

Public Release: 7-Oct-2013
Journal of Experimental Medicine
Study identifies essential molecule in formation of differentiated blood cells
New research in the Journal of Experimental Medicine identifies a protein that controls the formation of different types of mature blood cells -- a finding that could be important to developing new treatments for blood diseases and helping realize the potential of regenerative medicine. Reporting their results online Oct. 7, the authors focus on a protein that serves as a molecular switch in the cytoplasm of cells to control cell function.
National Institutes of Health, Medical Research Council, Deutsche Forschungsgemeinschaft, Alcon Research Institute

Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center

Public Release: 7-Oct-2013
Neuroscience
Stress steroid mediated withdrawal anxiety in dependent rats reversible by flumazenil
SUNY Downstate Medical Center announced today that Sheryl Smith, Ph.D., professor of physiology and pharmacology, has published new findings demonstrating a reproducible pathology that may help shed light on anxiety and mood volatility in methamphetamine dependence.
National Institutes of Health, Hythiam, Inc.

Contact: Sheryl Smith, Ph.D.
sheryl.smith@downstate.edu
516-353-4714
SUNY Downstate Medical Center

Public Release: 7-Oct-2013
Neurology
Study identifies possible biomarker for Parkinson's disease
Investigators from Beth Israel Deaconess Medical Center find that elevated levels of alpha-synuclein protein can be detected in the skin of Parkinson's disease patients.
National Institutes of Health, Langer Family Foundation, RJG Foundation

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center

Public Release: 7-Oct-2013
Proceedings of the National Academy of Sciences
3-D printed microscopic cages confine bacteria in tiny zoos for the study of infections
University of Texas at Austin researchers have used a novel 3-D printing technology to build homes for bacteria at a microscopic level. Their method uses a laser to construct protein "cages" around bacteria in gelatin. The resulting structures can be of almost any shape or size, and can be moved around in relationship to other structures containing bacterial microcommunities.
National Institutes of Health, Robert A. Welch Foundation

Contact: Jason Shear
jshear@mail.utexas.edu
512-232-1454
University of Texas at Austin

Public Release: 7-Oct-2013
Pediatrics
Air pollution and psychological distress during pregnancy
Maternal psychological distress combined with exposure to air pollution during pregnancy have an adverse impact on children's behavioral development. The study shows that maternal demoralization, a measure of psychological distress that can affect a mother's ability to cope with stressful situations, was linked with several behavioral problems, including anxiety, depression, and attention problems. Effects of demoralization were greatest among children with higher levels of prenatal exposure to polycyclic aromatic hydrocarbons in air pollution.
NIH/National Institute of Environmental Health Sciences

Contact: Stephanie Berger
sb2247@columbia.edu
212-305-4372
Columbia University's Mailman School of Public Health

Public Release: 7-Oct-2013
Proceedings of the National Academy of Sciences
Cells prefer nanodiscs over nanorods
For years scientists have been working to fundamentally understand how nanoparticles move throughout the human body. One big unanswered question is how the shape of nanoparticles affects their entry into cells. Now researchers have discovered that under typical culture conditions, mammalian cells prefer disc-shaped nanoparticles over those shaped like rods.
National Institutes of Health, National Science Foundation

Contact: Brett Israel
brett.israel@comm.gatech.edu
404-385-1933
Georgia Institute of Technology

Public Release: 7-Oct-2013
Health Affairs
Delayed aging is better investment than cancer, heart disease
Research to delay aging and the infirmities of old age would have better population health and economic returns than advances in individual fatal diseases such as cancer or heart disease, reveals study by top health scientists at USC, Harvard, Columbia and other institutions.
National Institutes of Health

Contact: Suzanne Wu
suzanne.wu@usc.edu
213-740-0252
University of Southern California

Public Release: 7-Oct-2013
Proceedings of the National Academy of Sciences
New more effective antimicrobials might rise from old
By tinkering with their chemical structures, researchers at the University of California, San Diego School of Medicine have essentially re-invented a class of popular antimicrobial drugs, restoring and in some cases, expanding or improving, their effectiveness against drug-resistant pathogens in animal models.
National Institutes of Health

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 6-Oct-2013
Nature Genetics
International coalition of researchers finds 6 new Sjögren's syndrome genes
Six new Sjögren's syndrome-related genes have been discovered by an international group of researchers in a genome-wide association study. Previously, only one Sjögren's gene was known.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH/National Institute of Allergy and Infectious Diseases, NIH/National Institute of Dental and Craniofacial Research, Sjögren's Syndrome Foundation

Contact: Greg Elwell
greg-elwell@omrf.org
405-271-8955
Oklahoma Medical Research Foundation

Public Release: 6-Oct-2013
Nature
CSHL neuroscientists identify class of cortical inhibitory neurons that specialize in disinhibition
New research now reveals that one class of inhibitory neurons -- called VIP interneurons -- specializes in inhibiting other inhibitory neurons in multiple regions of cortex, and does so under specific behavioral conditions. The new research finds that VIP interneurons, when activated, release principal cells from inhibition, thus boosting their responses. This provides an additional layer of control over cortical processing, much like a dimmer switch can fine-tune light levels.
NIH/National Institute of Neurological Disorders and Stroke, Klingenstein Foundation, John Merck Foundation, Sloan Foundation, Swartz Foundation, Curie Fellowship

Contact: Peter Tarr
tarr@cshl.edu
917-435-5068
Cold Spring Harbor Laboratory

Public Release: 6-Oct-2013
Nature Genetics
Massive DNA study points to new heart drug targets and a key role for triglycerides
A global hunt for genes that influence heart disease risk has uncovered 157 changes in human DNA that alter the levels of cholesterol and other blood fats -- a discovery that could lead to new medications. Each of the changes points to genes that can modify levels of cholesterol and other blood fats and are potential drug targets. Many of the changes point to genes not previously linked to blood fats, also called lipids.
National Institutes of Health, National Science Foundation

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 4-Oct-2013
Genome Research
Nano-dissection identifies genes involved in kidney disease
A new method developed by researchers at Princeton University and the University of Michigan called "in silico nano-dissection" uses computers rather than scalpels to separate and identify genes from specific cell types, enabling the systematic study of genes involved in diseases.
National Institutes of Health

Contact: Catherine Zandonella
czandone@princeton.edu
Princeton University

Public Release: 4-Oct-2013
Journal of Clinical Investigation
IU researchers, collaborators discover new therapeutic agents that may benefit leukemia patients
An Indiana University cancer researcher and his colleagues have discovered new therapeutic targets and drugs that may someday benefit people with certain types of leukemia or blood cancer.
National Institutes of Health

Contact: Michael Schug
maschug@iupui.edu
317-278-0953
Indiana University

Public Release: 4-Oct-2013
Blood
Stem cells engineered to become targeted drug factories
A group of Brigham and Women's Hospital, and Harvard Stem Cell Institute researchers and collaborators at MIT and MGH have found a way to use stem cells as drug delivery vehicles. The researchers inserted modified strands of messenger RNA into connective tissue stem cells -- called mesenchymal stem cells -- which stimulated the cells to produce adhesive surface proteins and secrete interleukin-10, an anti-inflammatory molecule.
National Institutes of Health

Contact: B. D. Colen
bd_colen@harvard.edu
617-413-1224
Harvard University

Public Release: 4-Oct-2013
ACS Chemical Biology
Rutgers scientists discover molecules that show promise for new anti-flu medicines
A new way to attack flu viruses is taking shape in laboratories at Rutgers University, where scientists have identified chemical agents that block the virus's ability to replicate itself in cell culture. These novel compounds show promise for a new class of antiviral medicines to fight much-feared pandemic influenza such as the looming "bird flu" threats caused by the H5N1 influenza A virus and the new H7N9 virus.
National Institutes of Health

Contact: Carl Blesch
cblesch@ucm.rutgers.edu
732-932-7084 x616
Rutgers University

Public Release: 4-Oct-2013
Cancer
High Medicare spending on prostate cancer screenings, but little benefit for older men
Prostate cancer screening has little benefit for men aged 75 and older, yet over three years, the Medicare fee-for-service program spent $447 million annually on PSA-based screenings -- one-third of which was for men in the over 75 age group, according to study by researchers at the Yale Cancer Outcomes, Public Policy, and Effectiveness Research Center.
National Institutes of Health

Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University

Public Release: 4-Oct-2013
Cancer Epidemiology, Biomarkers & Prevention
Cancer survivors in rural areas forgo health care because of cost
Older cancer survivors living in rural areas were more likely to forgo medical and dental care because of financial concerns compared with older cancer survivors living in urban areas, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
NIH/National Cancer Institute

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research

Public Release: 3-Oct-2013
Science
How an aggressive fungal pathogen causes mold in fruits and vegetables
A research team led by a University of California, Riverside molecular plant pathologist has discovered the mechanism by which an aggressive fungal pathogen infects almost all fruits and vegetables. The team discovered a novel virulence mechanism of Botrytis cinerea, a pathogen that can infect more than 200 plant species, causing serious gray mold disease on almost all fruits and vegetables that have been around, even at times in the refrigerator, for more than a week.
National Institutes of Health, National Science Foundation

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside

Public Release: 3-Oct-2013
Cell Stem Cell
Researchers unveil method for creating 're-specified' stem cells for disease modeling
A team led by researchers in the Boston Children's Hospital's Stem Cell Transplantation Program reports a new approach for turning induced pluripotent stem cells into hematopoietic stem and progenitor cells for in vivo disease modeling.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, NIH/National Heart, Lung and Blood Institute

Contact: Meghan Weber
meghan.weber@childrens.harvard.edu
617-919-3110
Boston Children's Hospital

Public Release: 3-Oct-2013
Menopause
New study suggests changing bacterial mix may lead to painful sex after menopause
The mix of bacteria in the vagina changes as women go through menopause. And a certain mix is typical after menopause in women who have vulvovaginal atrophy, a common cause of vaginal dryness and sexual pain, finds a team at Johns Hopkins and the University of Maryland. They suspect these bacteria may play a role in causing VVA.
National Institutes of Health

Contact: Eileen Petridis
epetridis@fallscommunications.com
216-696-0229
The North American Menopause Society (NAMS)

Public Release: 3-Oct-2013
Kessler Foundation's Krch awarded $600,000 NIDRR grant for virtual reality study in TBI
Denise Krch, PhD, research scientist at Kessler Foundation was awarded a 3-year, $600,000 NIDRR Field-Initiated Grant titled "The development of a virtual reality program to improve executive functioning in individuals with traumatic brain injury (TBI)." Scientists will develop a virtual reality-based intervention that targets problem solving, mental flexibility, and divided attention, and to pilot test the completed prototype in a small sample of individuals with TBI who have moderate to severe impairment in executive function.
NIH/National Institute on Disability & Rehabilitation Research

Contact: Carolann Murphy
CMurphy@KesslerFoundation.org
973-324-8382
Kessler Foundation

Public Release: 3-Oct-2013
PLOS Neglected Tropical Diseases
Innovative approach could ultimately end deadly disease of sleeping sickness
A tag team of two bacteria, one of them genetically modified, has a good chance to reduce or even eliminate the deadly disease African trypanosomiasis, or sleeping sickness, researchers at Oregon State University conclude in a recent mathematical modeling study.
National Institutes of Health

Contact: Jan Medlock
jan.medlock@oregonstate.edu
541-737-6874
Oregon State University

Showing releases 3301-3325 out of 3482.

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