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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3301-3325 out of 3402.

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Public Release: 1-May-2013
New England Journal of Medicine
Computer algorithms help find cancer connections
Using powerful algorithms developed by computer scientists at Brown University, medical researchers have assembled the most complete genetic profile yet of acute myeloid leukemia, an aggressive form of blood cancer. Findings are reported in the New England Journal of Medicine.
National Institutes of Health

Contact: Kevin Stacey
Brown University

Public Release: 1-May-2013
Science Translational Medicine
Genetic mutation linked with typical form of migraine
A research team led by a Howard Hughes Medical Institute investigator at the University of California, San Francisco has identified a genetic mutation that is strongly associated with a typical form of migraine.
National Institutes of Health

Contact: Jennifer O'Brien
University of California - San Francisco

Public Release: 1-May-2013
Study identifies genes, pathways altered during relaxation response practice
A new study from investigators at the Benson-Henry Institute for Mind/Body Medicine at Massachusetts General Hospital and Beth Israel Deaconess Medical Center finds that elicitation of the relaxation response -- a physiologic state of deep rest induced by practices such as meditation, deep breathing and prayer -- produces immediate changes in the expression of genes involved in immune function, energy metabolism and insulin secretion.
Centers for Disease Control and Prevention, NIH/National Center for Complementary and Alternative Medicine, NIH/National Center for Research Resources

Contact: Kristen Chadwick
Massachusetts General Hospital

Public Release: 1-May-2013
Genomics to reshape endometrial cancer treatment
The most in-depth look yet at endometrial cancer shows that adding genomics-based testing to the standard diagnostic workup could change the recommended course of treatment for some women.
National Institutes of Health

Contact: Caroline Arbanas
Washington University School of Medicine

Public Release: 1-May-2013
New England Journal of Medicine
Scientists assemble genetic playbook for acute leukemia
team of researchers led by Washington University School of Medicine in St. Louis has identified virtually all of the major mutations that drive acute myeloid leukemia, a fast-growing blood cancer in adults that often is difficult to treat.
National Institutes of Health, Barnes-Jewish Hospital Foundation

Contact: Caroline Arbanas
Washington University School of Medicine

Public Release: 1-May-2013
Brain region may hold key to aging
While the search continues for the Fountain of Youth, researchers may have found the body's "fountain of aging": the brain region known as the hypothalamus. For the first time, scientists at Albert Einstein College of Medicine of Yeshiva University report that the hypothalamus of mice controls aging throughout the body. Their discovery of a specific age-related signaling pathway opens up new strategies for combating diseases of old age and extending lifespan. The paper was published today in the online edition of Nature.
NIH/National Institute on Aging, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, American Diabetes Association

Contact: Kim Newman
Albert Einstein College of Medicine

Public Release: 1-May-2013
A paradigm shift in endometrial cancer
Results from the Cancer Genome Atlas Research Network may change the way endometrial cancers are classified and provide opportunities to test new treatment protocols for patients with this cancer.
National Institutes of Health

Contact: Marjorie Montemayor-Quellenberg
Brigham and Women's Hospital

Public Release: 1-May-2013
Mayo Clinic Proceedings
No link between anesthesia, dementia in elderly, Mayo Clinic Study finds
Elderly patients who receive anesthesia are no more likely to develop long-term dementia or Alzheimer's disease than other seniors, according to new Mayo Clinic research. The study analyzed thousands of patients using the Rochester Epidemiology Project -- which allows researchers access to medical records of nearly all residents of Olmsted County, Minn. -- and found that receiving general anesthesia for procedures after age 45 is not a risk factor for developing dementia. The findings were published Wednesday, May 1, online in Mayo Clinic Proceedings.
Mayo Clinic, NIH/National Center for Advancing Translational Sciences

Contact: Nick Hanson
Mayo Clinic

Public Release: 1-May-2013
Want to slow mental decay? Play a video game
A University of Iowa study shows that older people can put off the aging of their minds by playing a simple game that primes their processing speed skills. The research showed participants' cognitive skills improved in a range of functions, from improving peripheral vision to problem solving. Results published in the journal PLOS One.
National Institutes of Health

Contact: Richard Lewis
University of Iowa

Public Release: 1-May-2013
Journal of Clinical Investigation
Searching for therapeutic synergy in primary effusion lymphoma
In this issue of the Journal of Clinical Investigation, Juan Carlos Ramos and colleagues at the University of Miami used an immunocompromised mouse model of PEL to determine the efficacy of Bortezomib/Vorinostat combination therapy.
NIH/Developmental Center for AIDS Research, Dwoskin Family, Recio Foundations

Contact: Jillian Hurst
Journal of Clinical Investigation

Public Release: 30-Apr-2013
American Journal of Health Promotion
Virtual patient advocate delivers preconception care to improve pregnancy outcomes
Results of a pilot study suggest that a virtual patient advocate could help influence positive changes and help women have healthier pregnancies. Developed at Boston University School of Medicine, Boston Medical Center and Northeastern University, "Gabby" is an innovative tool developed to deliver preconception care to African-American women through interactive conversations online.
Agency for Healthcare Research and Quality, Health Resources and Services Administration, National Institutes of Health

Contact: Jenny Eriksen
Boston University Medical Center

Public Release: 30-Apr-2013
Proceedings of the National Academy of Sciences
Scientists find mutation driving pediatric brain tumors
A type of low-grade but sometimes lethal brain tumor in children has been found in many cases to contain an unusual mutation that may help to classify, diagnose and guide the treatment of the tumors, report scientists at Dana-Farber Cancer Institute.
Pediatric Low Grade Astrocytoma Foundation, National Institutes of Health

Contact: Anne Doerr
Dana-Farber Cancer Institute

Public Release: 30-Apr-2013
American Journal of Physiology - Gastrointestinal and Liver Physiology
Discovery helps explain how children develop rare, fatal disease
A team of biochemistry researchers at the University of Missouri has published conclusive scientific evidence that the gene ATP7A is essential for the dietary absorption of the nutrient copper. Their work with laboratory mice also provides a greater understanding of how this gene impacts Menkes disease as scientists search for a treatment.
National Institutes of Health

Contact: Christian Basi
University of Missouri-Columbia

Public Release: 30-Apr-2013
Journal of Adolescent Health
Teen girls less successful than boys at quitting meth in UCLA pilot research study
A UCLA-led study of adolescents receiving treatment for methamphetamine dependence has found that girls are more likely to continue using the drug during treatment than boys, suggesting that new approaches are needed for treating meth abuse among teen girls.
NIH/National Institute on Drug Abuse

Contact: Enrique Rivero
University of California - Los Angeles Health Sciences

Public Release: 30-Apr-2013
Nature Immunology
T cells rely on 'rheostat' to help ensure that the immune response matches the threat
A properly functioning immune system is a lesson in balance, providing protection against disease without attacking healthy tissue. Work led by St. Jude Children's Research Hospital scientists and published recently in Nature Immunology has identified a mechanism that helps T cells find that sweet spot where the strength of the immune response matches the threat.
National Institutes of Health, American-Lebanese-Syrian Associated Charities

Contact: Summer Freeman
St. Jude Children's Research Hospital

Public Release: 30-Apr-2013
Mast cells give clues in diagnosis, treatment of dengue
A protein produced by mast cells in the immune system may predict which people infected with dengue virus will develop life-threatening complications, according to researchers at Duke Medicine and Duke-National University of Singapore.
National Institutes of Health, National Medical Research Council of Singapore and the Duke-NUS Signature Research Program

Contact: Rachel Harrison
Duke University Medical Center

Public Release: 30-Apr-2013
Cancer Discovery
How some cancers 'poison the soil' to block metastasis
Cancer spread or metastasis can strike unprecedented fear in the minds of cancer patients. The "seed and the soil" hypothesis proposed by Stephen Paget in 1889 is now widely accepted to explain how cancer cells (seeds) are able to generate fertile soil (the microenvironment) in distant organs that promotes cancer's spread. However, this concept does not explain why some tumors do not spread or metastasize.
National Institutes of Health, Norwegian Cancer Society, Norwegian Research Council

Contact: Lauren Woods
Weill Cornell Medical College

Public Release: 30-Apr-2013
Annals of Emergency Medicine
Advancing emergency care for kids: Emergency physicians do it again
Most children with isolated skull fractures may not need to stay in the hospital, which finding has the potential to save the health care system millions of dollars a year. In addition, a new device more accurately estimates children's weights, leading to more precise drug dosing in the ER. Two studies published online this month in Annals of Emergency Medicine showcase some of the work emergency physicians are doing to improve care for children in the nation's emergency departments.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development

Contact: julie lloyd
American College of Emergency Physicians

Public Release: 30-Apr-2013
Estrogen fuels autoimmune liver damage
A Johns Hopkins Children's Center study in mice may help explain why women are more prone than men to a form of liver damage by implicating the female sex hormone estrogen in the development of autoimmune hepatitis.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Ekaterina Peshva
Johns Hopkins Medicine

Public Release: 30-Apr-2013
Stem Cells and Development
Identification of stem cells raises possibility of new therapies
Many diseases -- obesity, type 2 diabetes, muscular dystrophy -- are associated with fat accumulation in muscle. In essence, fat replacement causes the muscles to weaken and degenerate. Scientists at Wake Forest Baptist Medical Center have discovered the biological mechanism involved in this process, which could point the way to potential therapies.
NIH/National Institute on Aging, NIH/National Institute of Mental Health

Contact: Marguerite Beck
Wake Forest Baptist Medical Center

Public Release: 30-Apr-2013
Sleep duration associated with higher colorectal cancer risk
A new study is the first to report a significant positive association between long sleep duration and the development of colorectal cancer, especially among individuals who are overweight or snore regularly. The results raise the possibility that obstructive sleep apnea may contribute to cancer risk.
National Institutes of Health

Contact: Lynn Celmer
American Academy of Sleep Medicine

Public Release: 30-Apr-2013
Study finds possible alternative to bariatric weight loss surgery
An experimental procedure successfully tested in obese laboratory rats may provide a less-invasive alternative to bariatric weight-loss surgery. Scientists at Cincinnati Children's Hospital Medical Center used a catheter to redirect the flow of bile from the bile duct into the small intestine, producing the same metabolic and weight-loss benefits as bariatric surgeries such as gastric by-pass.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Ethicon Endo-Surgery

Contact: Nick Miller
Cincinnati Children's Hospital Medical Center

Public Release: 30-Apr-2013
Journal of Neuroscience
Neon exposes hidden ALS cells
A small group of neurons in the cortex play a big role in ALS (amyotrophic lateral sclerosis), a fatal disease. But the neurons have been difficult to study because they look so similar to others in the cortex. New research has isolated the brain's motor neurons that die in ALS and dressed them in a green fluorescent jacket. Now scientists can easily find them to study why they die and how to save them.
Les Turner ALS Foundation, NIH/National Institute of Neurological Disorders and Stroke, Wenske Foundation

Contact: Marla Paul
Northwestern University

Public Release: 30-Apr-2013
Clinical Cancer Research
Mayo Clinic finds experimental drug inhibits growth in all stages of common kidney cancer
Researchers at Mayo Clinic's campus in Florida have discovered a protein that is overly active in every human sample of kidney cancer they examined. They also found that an experimental drug designed to block the protein's activity significantly reduced tumor growth in animals when used alone. Combining it with another drug already used to treat the cancer improved the effectiveness of both.
NIH/National Cancer Institute

Contact: Kevin Punsky
Mayo Clinic

Public Release: 30-Apr-2013
Tiny worm sheds light on giant mystery about neurons
Scientists at the Oklahoma Medical Research Foundation studying neurons in Caenorhabditis elegans have found a gene, unc-16, that serves as a gatekeeper, restricting the flow of cellular organelles from the cell body to the axon. Organelles clogging the axon could potentially interfere with neuronal signaling or cause the axon to degenerate, leading to neurodegenerative disorders. This research is published in the May 2013 Genetics Society of America's journal GENETICS.
National Institutes of Health, Oklahoma Center for the Advancement of Science

Contact: Phyllis Edelman
Genetics Society of America

Showing releases 3301-3325 out of 3402.

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