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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 3301-3325 out of 3433.

<< < 128 | 129 | 130 | 131 | 132 | 133 | 134 | 135 | 136 | 137 > >>

Public Release: 7-Aug-2013
Nature Nanotechnology
DNA nanorobots find and tag cellular targets
Researchers have created a fleet of molecular "robots" that can home in on specific human cells and mark them for drug therapy or destruction. The nanorobots -- a collection of DNA molecules, some attached to antibodies -- were designed to seek a specific set of human blood cells and attach a fluorescent tag to the cell surfaces. Details of the system were published July 28, 2013, in the online edition of Nature Nanotechnology.
National Institutes of Health, National Science Foundation, NASA

Contact: Karin Eskenazi
ket2116@columbia.edu
212-342-0508
Columbia University Medical Center

Public Release: 7-Aug-2013
Journal of Neuroscience
Cognitive decline with age is normal, routine -- but not inevitable
Research on biochemical processes is making it clear that cognitive decline with age is a natural part of life, and scientists are tracking the problem down to highly specific components of the brain. Virtually everyone loses memory-making and cognitive abilities as they age. But of considerable interest is that it may not have to be that way.
National Institutes of Health

Contact: Kathy Magnusson
Kathy.magnusson@oregonstate.edu
541-737-6923
Oregon State University

Public Release: 7-Aug-2013
Psychological Science
Practice at 'guesstimating' can speed up math ability
There's a connection between how well a person does at the approximate number system and how skilled they become at the symbolic math they learn in school. Duke University researchers have shown that practice with approximations can help a person's speed at symbolic math problems.
National Institutes of Health

Contact: Karl Leif Bates
karl.bates@duke.edu
919-681-8054
Duke University

Public Release: 7-Aug-2013
Science Signaling
Loss of MicroRNA decoy might contribute to development of soft-tissue sarcoma
Researchers have discovered a novel mechanism responsible for the loss of a critical tumor-suppressor gene in rhabdomyosarcoma and other soft-tissue sarcomas, rare cancers that strike mainly children and often respond poorly to treatment. Their cause is largely unknown. Knowledge of the mechanism could guide the development of more effective therapies for these malignancies.
NIH/National Cancer Institute, Ohio State Univesity/Pelotonia fellowship

Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 7-Aug-2013
Journal of Neuroscience
Treadmill training after spinal cord injury promotes recovery when inflammation is controlled
New research suggests that treadmill training soon after a spinal cord injury can have long-lasting positive effects on recovery -- as long as the training is accompanied by efforts to control inflammation in the lower spinal cord.
National Institutes of Health

Contact: D. Michele Basso
Basso.2@osu.edu
614-292-0754
Ohio State University

Public Release: 7-Aug-2013
JAMA Dermatology
Psoriasis patients at increasing risk for range of serious medical conditions
Patients with mild, moderate and severe psoriasis had increasingly higher odds of having at least one major medical disease in addition to psoriasis, when compared to patients without psoriasis. Reporting findings in JAMA Dermatology, researchers from the Perelman School of Medicine at the University of Pennsylvania, concluded that the severity of disease, as measured by the percentage of body surface area affected by psoriasis, was strongly linked to an increased presence of other diseases affecting the lungs, heart, kidneys, liver and pancreas.
National Institutes of Health, National Psoriasis Foundation, American College of Rheumatology

Contact: Kim Menard
kim.menard@uphs.upenn.edu
215-662-6183
University of Pennsylvania School of Medicine

Public Release: 7-Aug-2013
Journal of the National Cancer Institute
Study suggests pattern in lung cancer pathology may predict cancer recurrence after surgery
A new study by thoracic surgeons and pathologists at Memorial Sloan-Kettering Cancer Center shows that a specific pattern found in the tumor pathology of some lung cancer patients is a strong predictor of recurrence. Knowing that this feature exists in a tumor's pathology could be an important factor doctors use to guide cancer treatment decisions.
NIH/National Cancer Institute, US Department of Defense

Contact: Esther Napolitano
napolite@mskcc.org
917-299-0291
Memorial Sloan-Kettering Cancer Center

Public Release: 7-Aug-2013
Neuron
Scripps Research Institute scientists find key signal that guides brain development
Scientists at the Scripps Research Institute have decoded an important molecular signal that guides the development of a key region of the brain known as the neocortex. The largest and most recently evolved region of the brain, the neocortex is particularly well developed in humans and is responsible for sensory processing, long-term memory, reasoning, complex muscle actions, consciousness and other functions.
National Institutes of Health, Dorris Neuroscience Center, Scripps Research Institute, California Institute of Regenerative Medicine, Spanish Ministry of Education, and others

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 7-Aug-2013
Nature
UW researchers publish study on genome of aggressive cervical cancer that killed Henrietta Lacks, subject of bestselling book
A team from the University of Washington has unveiled a comprehensive portrait of the genome of the world's first immortal cell line, known as HeLa. The cell line was derived in 1951 from an aggressive cervical cancer that killed Henrietta Lacks -- the subject of a bestselling book. They will also be the first group to publish under a new National Institutes of Health policy for HeLa genomic data, established through discussions with Lacks' family.
National Institutes of Health, Washington Research Foundation

Contact: Bobbi Nodell
bnodell@uw.edu
206-543-8309
University of Washington

Public Release: 7-Aug-2013
Neuron
A 'rocking' receptor: Crucial brain-signaling molecule requires coordinated motion to turn on
Johns Hopkins biophysicists have discovered that full activation of a protein ensemble essential for communication between nerve cells in the brain and spinal cord requires a lot of organized back-and-forth motion of some of the ensemble's segments. Their research, they say, may reveal multiple sites within the protein ensemble that could be used as drug targets to normalize its activity in such neurological disorders as epilepsy, schizophrenia, Parkinson's and Alzheimer's disease.
NIH/National Institute of General Medical Sciences, NeuroCure, Human Frontier Science Program

Contact: Catherine Kolf
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine

Public Release: 7-Aug-2013
New England Journal of Medicine
Scientists identify biomarker to predict immune response risk after stem cell transplants
Researchers have identified and validated a biomarker accessible in blood tests that could be used to predict which stem cell transplant patients are at highest risk for a potentially fatal immune response called graft-versus-host disease.
National Institutes of Health

Contact: Eric Schoch
eschoch@iu.edu
317-274-8205
Indiana University

Public Release: 7-Aug-2013
Neuron
Why don't we all get Alzheimer's disease?
Researchers at the University of California, San Diego School of Medicine offer an explanation for why we all don't get Alzeimer's disease (AD) -- a trick of nature that in most people maintains critical separation between a protein and an enzyme that, when combined, trigger the progressive cell degeneration and death characteristic of AD.
American Federation for Aging Research, National Institutes of Health

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 7-Aug-2013
New England Journal of Medicine
Dementia risk tied to blood sugar level, even with no diabetes
Diabetes is a risk factor for dementia. But now a joint Group Health–University of Washington study in the New England Journal of Medicine has found that higher blood sugar levels are associated with higher dementia risk, even among people who do not have diabetes. The higher the blood sugar level, averaged over five years, the higher the risk for developing dementia, in this report about more than 2,000 Group Health patients.
NIH/National Institute on Aging

Contact: Rebecca Hughes
hughes.r@ghc.org
206-287-2055
Group Health Research Institute

Public Release: 6-Aug-2013
Proceedings of the National Academy of Sciences
Protein changes are discovered that control whether a gene functions
Changes to proteins called histones, which are associated with DNA, can control whether or not a gene is allowed to function. The changes may be important in maintaining the genes' "expression potential" so that future cells behave as their parent cells did. The discovery, which may have implications for the study of diseases such as cancer, will be published in a print edition of the journal Proceedings of the National Academy of Sciences.
National Institutes of Health

Contact: Barbara K. Kennedy
814-863-4682
Penn State

Public Release: 6-Aug-2013
Journal of Neuroscience
Ohio State researchers restore immune function in spinal injured mice
In a new study, researchers at the Center for Brain and Spinal Cord Repair at the Ohio State University Wexner Medical Center show that is possible to restore immune function in spinal injured mice. People with spinal cord injury often are immune compromised, which makes them more susceptible to infections. Why these people become immune-suppressed is not known, but the Ohio State study found that a disorder called autonomic dysreflexia can cause immune suppression.
National Institutes of Health, Ray W. Poppleton Endowment

Contact: Eileen Scahill
Eileen.Scahill@osumc.edu
614-293-3737
Ohio State University Wexner Medical Center

Public Release: 6-Aug-2013
LA Tumor Registry at LSUHSC receives $1.3 million from NCI
The Louisiana Tumor Registry at the LSU Health Sciences Center New Orleans School of Public Health has been awarded a $1.3 million contract by the National Cancer Institute to continue its work as a SEER Program-designated cancer registry. There are 18 competitively awarded SEER cancer registries in the United States.
NIH/National Cancer Institute

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center

Public Release: 6-Aug-2013
Journal of Clinical Investigation
Vaccine stirs immune activity against advanced, hard-to-treat leukemia
Dana-Farber scientists report in the Journal of Clinical Investigation they have developed a tumor vaccine based on the patient's tumor to create a strong and selective immune response in some chronic lymphocytic leukemia patients.
NIH/National Cancer Institute, NIH/National Heart, Lung and Blood Inst, Claudia Adams Barr Program, L&LS

Contact: Teresa Herbert
teresa_herbert@dfci.harvard.edu
617-632-4090
Dana-Farber Cancer Institute

Public Release: 6-Aug-2013
Journal of Bacteriology
New design may produce heartier, more effective salmonella-based vaccines
Through genetic manipulation, the species S. Typhi can be rendered harmless and used in vaccines in order to prevent, rather than cause illness. ASU scientists describe efforts to improve the effectiveness of a Recombinant Attenuated Salmonella Vaccine by modifying its ability to survive the hostile environment of the stomach.
National Institutes of Health

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-727-0369
Arizona State University

Public Release: 6-Aug-2013
Human Reproduction
Length of human pregnancies can vary naturally by as much as 5 weeks
The length of a human pregnancy can vary naturally by as much as five weeks, according to research published in Europe's leading reproductive medicine journal Human Reproduction. For the first time, researchers in the USA have been able to pinpoint the precise point at which a woman ovulates and a fertilized embryo implants in the womb during a naturally conceived pregnancy, and follow the pregnancy through to delivery.
NIH/Intramural Research Program, NIH/National Institute of Environmental Health Sciences

Contact: Emma Mason
wordmason@mac.com
European Society of Human Reproduction and Embryology

Public Release: 6-Aug-2013
JAMA
Treating PTSD and alcohol abuse together doesn't increase drinking, Penn study finds
Contrary to past concerns, using prolonged exposure therapy to treat patients with post-traumatic stress disorder and comorbid alcohol dependence does not increase drinking or cravings, Penn Medicine psychiatrists report in the Aug. 7 issue of JAMA, a theme issue on violence/human rights.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Steve Graff
stephen.graff@uphs.upenn.edu
215-301-5221
University of Pennsylvania School of Medicine

Public Release: 6-Aug-2013
PLOS Medicine
CD4 count is non-inferior to viral load for treatment switching in adults with HIV
For adults infected with HIV in Thailand a monitoring strategy based on CD4 count (a type of white blood cell) is non-inferior to the recommended monitoring strategy measuring the amount of HIV virus in a patient's blood, to determine when to switch from first-line to more costly second-line antiretroviral treatment according to a clinical trial published this week in PLOS Medicine.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development

Contact: Fiona Godwin
medicinepress@plos.org
01-223-442-834
PLOS

Public Release: 5-Aug-2013
Circulation
Smoke-free casinos reduce medical emergencies
Commercial casinos throughout the country are often exempt from smoke-free workplace laws. Now a new study led by UC San Francisco has found that when smoking is banned in casinos, it results in considerably fewer emergency calls for ambulances.
NIH/National Cancer Institute

Contact: Elizabeth Fernandez
elizabeth.fernandez@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 5-Aug-2013
Nature Structural and Molecular Biology
Tumors elude anti-cancer drugs through 'fork reversal' repair, SLU scientists discover
Researchers hope to combine new RECQ1 inhibitors with existing drugs to create more effective therapies with fewer toxic side effects.
National Institutes of Health

Contact: Carrie Bebermeyer
bebermcl@slu.edu
314-977-8015
Saint Louis University

Public Release: 5-Aug-2013
Journal of Acquired Immune Deficiency Syndromes
Trial finds more support for universal HIV screening in emergency departments
Screening everyone for HIV in the emergency department may be superior to testing only those with apparent risk, when trying to identify patients with undiagnosed HIV infection, according to a new results by researchers at the University of Cincinnati and published in the Journal of Acquired Immune Deficiency Syndromes.
National Institutes of Health

Contact: Katy Cosse
kathryn.cosse@uc.edu
513-558-0207
University of Cincinnati Academic Health Center

Public Release: 5-Aug-2013
Angewandte Chemie
Scripps Florida scientists devise new way to dramatically raise RNA treatment potency
Scientists from the Jupiter campus of the Scripps Research Institute have shown a novel way to dramatically raise the potency of drug candidates targeting RNA, resulting in a 2,500-fold improvement in potency and significantly increasing their potential as therapeutic agents.
National Institutes of Health, Scripps Research Institute

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute

Showing releases 3301-3325 out of 3433.

<< < 128 | 129 | 130 | 131 | 132 | 133 | 134 | 135 | 136 | 137 > >>

     
   

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