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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3326-3350 out of 3525.

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Public Release: 19-Dec-2013
TB bacteria mask their identity to intrude into deeper regions of lungs
TB-causing bacteria appear to mask their identity to avoid recognition by infection-killing cells in the well-patrolled upper airways. The bacteria call up more permissive white blood cells in the deeper regions of the lungs and hitch a ride inside them to get into parts of the host's lungs that are under less surveillance.
National Science Foundation, American Lung Association, American Cancer Society, National Institutes of Health

Contact: Leila Gray
University of Washington

Public Release: 19-Dec-2013
Cell Reports
How cells remodel after UV radiation
Researchers at the University of California, San Diego School of Medicine, with colleagues in The Netherlands and United Kingdom, have produced the first map detailing the network of genetic interactions underlying the cellular response to ultraviolet radiation.
National Institutes of Health, Netherlands Organization for Scientific Research

Contact: Scott LaFee
University of California - San Diego

Public Release: 19-Dec-2013
Nutrition influences metabolism through circadian rhythms, UCI study finds
A high-fat diet affects the molecular mechanism controlling the internal body clock that regulates metabolic functions in the liver, UC Irvine scientists have found. Disruption of these circadian rhythms may contribute to metabolic distress ailments, such as diabetes, obesity and high blood pressure.
National Institutes of Health, National Science Foundation, Merieux Research Institute, Sirtiris/GSK

Contact: Tom Vasich
University of California - Irvine

Public Release: 19-Dec-2013
American Journal of Public Health
Lactation consultant visits spur breastfeeding among women who usually resist it
In two separate clinical trials, researchers at Albert Einstein College of Medicine of Yeshiva University have found that periodic meetings with a lactation consultant encourages women traditionally resistant to breastfeeding to do so, at least for a few months--long enough for mother and child to gain health benefits. The results of the trials were published online today in American Journal of Public Health.
National Institutes of Health

Contact: Kim Newman
Albert Einstein College of Medicine

Public Release: 19-Dec-2013
Study confirms target of potent chronic leukemia drug
A new study helps confirm that a molecule targeted by the experimental drug ibrutinib is critical for the development of chronic lymphocytic leukemia, the most common form of adult leukemia.
Leukemia and Lymphoma Society, D. Warren Brown Foundation, NIH/National Cancer Institute

Contact: Darrell E. Ward
Ohio State University Wexner Medical Center

Public Release: 19-Dec-2013
PLOS Genetics
Protein links liver cancer with obesity, alcoholism, and hepatitis
A new study identifies an unexpected molecular link between liver cancer, cellular stress, and risk factors for developing this cancer -- obesity, alcoholism, and viral hepatitis. In the study by University of Iowa researchers and published in the journal PLOS Genetics, researchers show that a protein called CHOP, which had previously been thought to generally protect against cancer, actually promotes liver cancer in mice.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Carver Medical Research Trust Initiative, NIH/National Cancer Institute

Contact: Jennifer Brown

Public Release: 19-Dec-2013
Scientists look to tackle bacterium that is major cause of diarrhea, vomiting
Scientists want to make a chink in the armor of a bacterium that has little name recognition yet is the number-one bacterial cause of the diarrhea, vomiting and stomach pain Americans experience annually.
National Institutes of Health

Contact: Toni Baker
Medical College of Georgia at Georgia Regents University

Public Release: 19-Dec-2013
Researchers find a cause of aging that can be reversed
Medical researchers have found a cause of ageing in animals that can be reversed, possibly paving the way for new treatments for age-related diseases including cancer, type 2 diabetes, muscle wasting and inflammatory diseases.
NIH/National Institute on Aging, Glenn Foundation for Medical Research

Contact: Susi Hamilton
University of New South Wales

Public Release: 19-Dec-2013
Current Biology
Renegades of cell biology: Why K-Ras gene mutations prove so deadly in cancer
Cells with a mutation in the gene called K-Ras--found in close to 30 percent of all cancers, but mostly those with worst prognosis, such as pancreatic cancer, colon cancer, and lung cancer -- behave in ways that subvert the normal mechanisms of cell death, according to a cell-culture study by researchers from Huntsman Cancer Institute at the University of Utah.
National Institutes of Health

Contact: Linda Aagard
University of Utah Health Sciences

Public Release: 19-Dec-2013
PLOS Genetics
Amino acid's increase is suspected in diabetes
Scientists at The University of Texas Health Science Center at San Antonio conducted research that suggests the amino acid tyrosine has a direct effect in diabetes.
NIH/National Institute on Aging, National Institute of Environmental Health Sciences, Geriatric Research, Education and Clinical Center of the South Texas Veterans Health Care System

Contact: Will Sansom
University of Texas Health Science Center at San Antonio

Public Release: 19-Dec-2013
PLOS Pathogens
Biologists find clues to a parasite's inconsistency
MIT researchers find that certain strains of Toxoplasma provoke inflammation that can damage host cells, while others are harmless.
New England Regional Center of Excellence, Pew Scholars Program in the Biomedical Sciences, Robert A. Swanson Career Development Award, Knights Templar Eye Foundation, Wellcome Trust Foundation, National Institutes of Health

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 19-Dec-2013
Cell Stem Cell
Brain repair after injury and Alzheimer's disease
Scientists at Penn State University have developed an innovative technology to regenerate functional neurons after brain injury. The technology may be developed into a new therapeutic treatment for traumatic brain and spinal cord injuries, stroke, Alzheimer's disease, Parkinson's disease, and other neurological disorders.
National Institutes of Health, Penn State University Eberly College of Science

Contact: Barbara K. Kennedy
Penn State

Public Release: 19-Dec-2013
PLOS Genetics
Protein links liver cancer with obesity, alcoholism, and hepatitis
A new study identifies an unexpected molecular link between liver cancer, cellular stress, and risk factors for developing this cancer -- obesity, alcoholism, and viral hepatitis. The study by University of Iowa researchers shows that a protein called CHOP, which had previously been thought to generally protect against cancer, actually promotes liver cancer in mice and may do the same in humans. The findings are published Dec. 19 in the journal PLOS Genetics.
NIH/National Institute of Diabetes, Digestive, and Kidney Disorders

Contact: Jennifer Brown
University of Iowa Health Care

Public Release: 19-Dec-2013
Gladstone scientists discover how immune cells die during HIV infection; identify potential drug to block AIDS
Research led by scientists at the Gladstone Institutes has identified the chain of molecular events that drives the death of the immune system's CD4 T cells as an HIV infection leads to AIDS. Further, they have identified an existing anti-inflammatory drug that blocks the death of these cells -- and now are planning a Phase 2 clinical trial to determine if it can prevent HIV-infected people from developing AIDS.
National Institutes of Health, A.P. Giannini Postdoctoral Research Fellowship, University of California San Francisco/Robert John Sabo Trust Award

Contact: Anne Holden
Gladstone Institutes

Public Release: 19-Dec-2013
Stroke: Journal of the American Heart Association
Anxiety linked to higher long-term risk of stroke
This is the first study to link anxiety to a greater risk of stroke.
NIH/National Heart, Lung, and Blood Institute, NIH/National Institute of Mental Health

Contact: Darcy Spitz
American Heart Association

Public Release: 19-Dec-2013
Team finds new way to map important drug targets
Researchers have used new techniques and one of the brightest X-ray sources on the planet to map the 3-D structure of an important cellular gatekeeper in a more natural state than possible before.
National Institutes of Health, National Science Foundation

Contact: Mika Ono
Scripps Research Institute

Public Release: 19-Dec-2013
PLOS Genetics
Stowers researchers announce first genetic model of a human jaw fusion defect known as syngnathia
The face you critiqued in the mirror this morning was sculpted before you were born by a transient population of cells called neural crest cells. Those cells spring from neural tissue of the brain and embryonic spinal cord and travel throughout the body, where they morph into highly specialized bone structures, cartilage, connective tissue, and nerve cells.
NIH/National Institute of Dental and Craniofacial Research, March of Dimes, and others

Contact: Gina Kirchweger
Stowers Institute for Medical Research

Public Release: 19-Dec-2013
A new -- and reversible -- cause of aging
Researchers have discovered a cause of aging in mammals involving a series of molecular events that disables communication between the nucleus and mitochondria. By administering a molecule naturally produced by the human body, the communication network was restored in older mice. Subsequent tissue samples showed biological hallmarks comparable to much younger animals.
NIH/National Institute on Aging, Glenn Foundation for Medical Research, and others

Contact: David Cameron
Harvard Medical School

Public Release: 19-Dec-2013
Cocaine, meth response differ between 2 substrains of 'Black 6' laboratory mouse
Researchers including Jackson Laboratory Professor Gary Churchill, Ph.D., have found a single nucleotide polymorphism difference in cocaine and methamphetamine response between two substrains of the C57BL/6 or "Black 6" inbred laboratory mouse, pointing to Cyfip2 as a regulator of cocaine response with a possible role in addiction.
NIH/National Institute on Drug Abuse

Contact: Joyce Peterson
Jackson Laboratory

Public Release: 19-Dec-2013
Gene transfer gone wild reveals driving force behind mitochondrial sex
Pioneering research led by Indiana University has identified genes from a number of plant species, including the entire mitochondrial genomes from three green algae and one moss, in the mitochondrial genome of Amborella trichopoda. The South Pacific shrub is considered to be the sole survivor -- the "last man standing" -- of one of the two oldest lineages of flowering plants, while the other lineage comprises the other 300,000 species of flowering plants.
National Institutes of Health, National Science Foundation, US Department of Energy

Contact: Stephen Chaplin
Indiana University

Public Release: 18-Dec-2013
Stem Cells
Stem cells offer clues to reversing receding hairlines
Regenerative medicine may offer ways to banish baldness that don't involve toupees. The lab of USC scientist Krzysztof Kobielak, M.D., Ph.D., has published a trio of papers in the journals Stem Cells and The Proceedings of the National Academy of Sciences that describe some of the factors that determine when hair grows, when it stops growing and when it falls out.
National Institutes of Health, California Institute for Regenerative Medicine

Contact: Cristy Lytal
University of Southern California - Health Sciences

Public Release: 18-Dec-2013
Fatigue, a common side effect of breast cancer treatment, evaluated in novel patient study
Although the prevalence and impact of cancer-related fatigue has been well established, very little is known about its predictors, mechanisms for development, and persistence post-treatment. A new research study at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, in partnership with UCLA, is aimed at identifying breast cancer patients most susceptible to post-treatment fatigue by measuring biological, behavioral and social risk factors.
National Institutes of Health

Contact: Cara Martinez
Cedars-Sinai Medical Center

Public Release: 18-Dec-2013
Journal of Clinical Investigation
Role for sugar uptake in breast cancer revealed
Berkeley Lab researchers have shown that aerobic glycolysis -- glucose metabolism in the presence of oxygen -- is not the consequence of the cancerous activity of malignant cells, as has been widely believed, but is itself a cancerous event.
NIH/National Cancer Institute

Contact: Lynn Yarris
DOE/Lawrence Berkeley National Laboratory

Public Release: 18-Dec-2013
Neanderthal genome shows early human interbreeding, inbreeding
A team that includes UC Berkeley population geneticists has produced the first high-quality genome of a Neanderthal, allowing comparison with the genomes of modern humans and Denisovans. The analysis shows a long history of interbreeding among these early humans and a fourth, previously unknown group. The Neanderthal, from Denisova cave, also shows evidence of inbreeding. About 87 genes in modern humans were found to be significantly different from related genes in Neanderthals and Denisovans.
National Institutes of Health

Contact: Robert Sanders
University of California - Berkeley

Public Release: 18-Dec-2013
Nature Communications
Going against the flow: Halting atherosclerosis by targeting micro RNA
Researchers at Emory and Georgia Tech have developed a potential treatment for atherosclerosis that targets a master controller of the process.
NIH/National Heart, Lung and Blood Institute

Contact: Quinn Eastman
Emory Health Sciences

Showing releases 3326-3350 out of 3525.

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