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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 3326-3350 out of 3465.

<< < 129 | 130 | 131 | 132 | 133 | 134 | 135 | 136 | 137 | 138 > >>

Public Release: 3-Oct-2013
PLOS Neglected Tropical Diseases
Innovative approach could ultimately end deadly disease of sleeping sickness
A tag team of two bacteria, one of them genetically modified, has a good chance to reduce or even eliminate the deadly disease African trypanosomiasis, or sleeping sickness, researchers at Oregon State University conclude in a recent mathematical modeling study.
National Institutes of Health

Contact: Jan Medlock
jan.medlock@oregonstate.edu
541-737-6874
Oregon State University

Public Release: 3-Oct-2013
Public Library of Science
Stem cells help repair traumatic brain injury by building a 'biobridge'
University of South Florida researchers suggest a new view of how stem cells may help repair the brain following trauma.
SanBio Inc, James and Esther King Biomedical Research Foundation, National Institutes of Health, Celgene Cellular Therapeutics

Contact: Anne DeLotto Baier
abaier@health.usf.edu
813-974-3303
University of South Florida (USF Health)

Public Release: 3-Oct-2013
DNA nanotechnology opens new path to super-high-resolution molecular imaging
A team at the Wyss Institute for Biologically Inspired Engineering at Harvard University has been awarded a special $3.5 million grant from the National Institutes of Health to develop an inexpensive and easy-to-use new microscopy method that uses blinking DNA probes to spot many tiny components of cells simultaneously. The method could potentially lead to new ways of diagnosing disease and new insights into how the cell's components carry out their work.
National Institutes of Health

Contact: Dan Ferber
dan.ferber@wyss.harvard.edu
617-432-1547
Wyss Institute for Biologically Inspired Engineering at Harvard

Public Release: 3-Oct-2013
CHOP genetics expert co-leads NIH grant on psychiatric illness in patients with deletion syndrome
Genetics experts from The Children's Hospital of Philadelphia are among the top leaders of a major international collaboration researching why patients with chromosome 22q11.2 deletion syndrome have an elevated risk of schizophrenia and other psychiatric illnesses. Discovering genes implicated in the deletion syndrome, a multisystem disorder, may offer important clues to the biological causes of mental illness in the general population.
NIH/National Institute of Mental Health

Contact: John Ascenzi
ascenzi@email.chop.edu
267-426-6055
Children's Hospital of Philadelphia

Public Release: 3-Oct-2013
Penn co-leads $12 M NIH grant to study genetics of mental illnesses in deletion syndrome patients
A major international consortium co-led by Penn Medicine has received a $12 million National Institute of Mental Health grant for a large-scale genetics study investigating why patients with chromosome 22q11.2 deletion syndrome have an increased risk of schizophrenia and other psychiatric disorders.
NIH/National Institute of Mental Health

Contact: Steve Graff
stephen.graff@uphs.upenn.edu
215-349-5653
University of Pennsylvania School of Medicine

Public Release: 3-Oct-2013
PLOS ONE
LSUHSC researcher discovers target for new Rx class for inflammatory disorders
Research led by Charles Nichols, Ph.D., Associate Professor of Pharmacology at LSU Health Sciences Center New Orleans, describes a powerful new anti-inflammatory mechanism that could lead to the development of new oral medications for atherosclerosis and inflammatory bowel disorders. The findings are published in PLOS ONE, available online at http://dx.plos.org/10.1371/journal.pone.0075426.
NIH/National Heart, Lung, Blood Institute

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center

Public Release: 3-Oct-2013
Cell
Blocking nerve cells could prevent symptoms of eczema
UC Berkeley research is leading to a new picture of how the nervous system interacts with the immune system to cause the itch and inflammation of eczema, a chronic skin disease. The new findings by neuroscientists Diana Bautista and Sarah Wilson could lead to new therapies for the condition, which afflicts 10 percent of the population at some point in their lives. In children, dry and itchy skin can progress to rashes, nasal allergies and asthma.
National Institutes of Health

Contact: Robert Sanders
rlsanders@berkeley.edu
510-643-6998
University of California - Berkeley

Public Release: 3-Oct-2013
Journal of Biological Chemistry
Scripps Florida scientists identify potential new drug for inherited cancer
Scientists from the Florida campus of The Scripps Research Institute have identified a new drug candidate for an inherited form of cancer with no known cure.
National Institutes of Health, American Cancer Society, Afraxis, Inc.

Contact: Eric Sauter
esauter@scripps.edu
267-337-3859
Scripps Research Institute

Public Release: 3-Oct-2013
Cancer Cell
Triple-negative breast cancer target for drug development identified
Often deadly "triple-negative" breast cancers might be effectively treated in many cases with a drug that targets a previously unknown vulnerability in the tumors, according to a UC San Francisco researcher who described her discovery in a study published online October 3, 2013 in the journal Cancer Cell.
National Institutes of Health, Bay Area Breast Cancer Specialized Program Of Research Excellence, Durra Family Fund, Mount Zion Health Fund, Prospect Creek Foundation

Contact: Jeffrey Norris
jeffrey.norris@ucsf.edu
415-502-6397
University of California - San Francisco

Public Release: 3-Oct-2013
Science Express
Possible culprits in congenital heart defects identified
Mitochondria are the power plants of cells, manufacturing fuel so a cell can perform its many tasks. Mitochondria also are well known for their role in cell suicide. Now, researchers at Washington University School of Medicine in St. Louis and the University of Padua-Dulbecco Telethon Institute in Italy have shown that mitochondria also orchestrate events that determine a cell's future. The study identifies new potential genetic culprits in the origins of some congenital heart defects.
National Institutes of Health, Italian Telethon, ISHR-ES/SERVIER, Oncosuisse, AIRC, ERC

Contact: Julia Evangelou Strait
straitj@wustl.edu
314-286-0141
Washington University School of Medicine

Public Release: 3-Oct-2013
Science
Silencing sudden death
Hypertrophic cardiomyopathy -- a disease in which cardiac muscle thickens, weakening the heart -- can be prevented from developing for several months in mice by reducing production of a mutant protein.
NIH/National Heart, Lung, and Blood Institute

Contact: David J Cameron
david_cameron@hms.harvard.edu
617-432-0441
Harvard Medical School

Public Release: 3-Oct-2013
Molecular Cell
How a 'mistake' in a single-cell organism is actually a rewrite essential to life
A tiny but unexpected change to a segment of RNA in a single-cell organism looks a lot like a mistake, but is instead a change to the genetic information that is essential to the organism's survival.
National Institutes of Health

Contact: Juan Alfonzo
Alfonzo.1@osu.edu
614-292-0004
Ohio State University

Public Release: 3-Oct-2013
IDWeek 2013
JAMA Internal Medicine
High rates of unnecessary prescribing of antibiotics observed across the US
For decades, there has been a significant effort led by the Centers for Disease Control and Prevention and others to reduce inappropriate antibiotic prescribing. Despite this work, new research from Brigham and Women's Hospital finds only incremental improvement in antibiotic prescribing for adults with acute bronchitis and sore throat. These findings were presented at IDWeek on October 3, 2013 and the sore throat data was published online in JAMA Internal Medicine.
National Institutes of Health, NIH/National Institute of Allergy and Infectious Disease, Agency for Healthcare Research and Quality

Contact: Lori J Schroth
ljschroth@partners.org
617-534-1604
Brigham and Women's Hospital

Public Release: 3-Oct-2013
PeerJ
Power of precision medicine shown in successful treatment of patient with disabling OCD
A multidisciplinary team led by a geneticist and psychiatrist from CSHL's Stanley Institute for Cognitive Genomics have published a paper providing a glimpse of both the tremendous power and the current limitations of "precision medicine."
National Institutes of Health, Stanley Institute for Cognitive Genomics

Contact: Peter Tarr
tarr@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory

Public Release: 3-Oct-2013
Science
Analysis of little-explored regions of genome reveals dozens of potential cancer triggers
A massive data analysis of natural genetic variants in humans and variants in cancer tumors has implicated dozens of mutations in the development of breast and prostate cancer, a Yale-led team has found. The newly discovered mutations are in regions of DNA that do not code for proteins but instead influence activity of other genes. These areas represent an unexplored world that will allow researchers and doctors to gain new insight into the causes and treatment of cancer, said the scientists.
National Institutes of Health

Contact: Bill Hathaway
william.hathaway@yale.edu
203-432-1322
Yale University

Public Release: 2-Oct-2013
NIH awards grant for new NYU step program created to bolster biomedical research training
The National Institutes of Health has awarded a five-year grant to Keith J. Micoli, postdoctoral program director, NYU School of Medicine, Sackler Institute of Graduate Biomedical Sciences, and Carol Shoshkes Reiss, professor, Departments of Biology and Neural Science at NYU, to enhance the training of biomedical graduate students and postdoctoral scholars to prepare them for a wide range of careers.
National Institutes of Health

Contact: James Devitt
james.devitt@nyu.edu
212-998-6808
New York University

Public Release: 2-Oct-2013
VCU receives federal grant to study genetic markers that may predict chronic depression
Virginia Commonwealth University has received a $3 million grant from the National Institute of Mental Health to study key molecular markers found in DNA that predict chronic depression.
National Institutes of Health

Contact: Cassie Williams Jones
cwjones@vcu.edu
804-828-7028
Virginia Commonwealth University

Public Release: 2-Oct-2013
Erectile dysfunction drugs may prevent colon cancer
Erectile dysfunction drugs may be able to help prevent or even treat colon cancer, researchers say.
NIH/National Cancer Institute

Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University

Public Release: 2-Oct-2013
Scientific Reports
New method allows quantitative nanoscopic imaging through silicon
A team of scientists from The University of Texas at Arlington and MIT has figured out how to quantitatively observe cellular processes taking place on so-called "lab on a chip" devices in a silicon environment. The new technology, which is published in Nature's online journal Scientific Reports, will be useful in drug development as well as disease diagnosis, researchers say.
NIH/National Institute of Biomedical Imaging and Bioengineering

Contact: Traci Peterson
tpeterso@uta.edu
817-521-5494
University of Texas at Arlington

Public Release: 2-Oct-2013
CWRU researchers probe brain implant failure and countermeasure
A team of researchers led by Case Western Reserve University has received a $1.8 million National Institutes of Health grant to investigate why brain implants fail, and to test a drug that may prevent such failure.
National Institutes of Health

Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-368-4442
Case Western Reserve University

Public Release: 2-Oct-2013
Researchers launch first-ever phase II safety study of rectal microbicide to prevent HIV
Taking an important step toward the development of a product to prevent HIV infections associated with unprotected anal sex, researchers today announced the launch of a global Phase II clinical trial of a potential rectal microbicide. The trial, led by the US National Institutes of Health-funded Microbicide Trials Network, is testing the rectal use of a reduced glycerin gel formulation of the antiretroviral drug tenofovir.
National Institutes of Health

Contact: Clare Collins
collcx@upmc.edu
412-641-7299
Microbicide Trials Network

Public Release: 2-Oct-2013
New England Journal of Medicine
Long-term cognitive impairment too common after critical illness
Patients treated in intensive care units across the globe are entering their medical care with no evidence of cognitive impairment but oftentimes leaving with deficits similar to those seen in patients with traumatic brain injury or mild Alzheimer's disease that persists for at least a year, according to a Vanderbilt study published today in the New England Journal of Medicine.
National Institutes of Health, Geriatric Research Education and Clinical Centers

Contact: Craig Boerner
craig.boerner@vanderbilt.edu
615-322-4747
Vanderbilt University Medical Center

Public Release: 2-Oct-2013
Science Translational Medicine
Newly identified biomarkers help predict outcome in deadly lung disease
A Yale-led study has identified a gene expression profile that can predict outcomes and lead to better treatment for one of the most lethal lung diseases, idiopathic pulmonary fibrosis. The study appears in Science Translational Medicine.
NIH/ National Heart, Lung, and Blood Institute, National Institutes of Health

Contact: Helen Dodson
helen.dodson@yale.edu
203-436-3984
Yale University

Public Release: 2-Oct-2013
Nature
Scientists find insect DEET receptors, develop safe alternatives to DEET
Researchers at the University of California, Riverside have identified (1) DEET-detecting olfactory receptors in insects that cause repellency and (2) three safe compounds that mimic DEET and could one day be used to prevent the transmission of deadly vector-borne diseases. Until now, no one had a clue about which olfactory receptor insects used to avoid DEET. Without the receptors, it was impossible to apply modern technology to design new repellents to improve upon DEET.
NIH/National Institute of Allergy and Infectious Diseases, NIH/National Institute of Neurological Disorders

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside

Public Release: 1-Oct-2013
Journal of Leukocyte Biology
Cocaine use can make otherwise resistant immune cells susceptible to HIV
Cocaine makes otherwise resistant immune cells susceptible to infection with HIV, causing both significant infection and new production of the virus.
NIH/National Institute on Drug Abuse

Contact: Enrique Rivero
erivero@mednet.ucla.edu
310-794-2273
University of California - Los Angeles Health Sciences

Showing releases 3326-3350 out of 3465.

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