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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3351-3375 out of 3452.

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Public Release: 9-Sep-2013
Molecular Therapy
Therapy slows onset and progression of Lou Gehrig's disease, study finds
Studies of a therapy designed to treat amyotrophic lateral sclerosis suggest that the treatment dramatically slows onset and progression of the deadly disease, one of the most common neuromuscular disorders in the world. The researchers found a survival increase of up to 39 percent in animal models with a one-time treatment, a crucial step toward moving the therapy into human clinical trials.
National Institutes of Health, Packard Center for ALS Research

Contact: Gina Bericchia
Nationwide Children's Hospital

Public Release: 9-Sep-2013
Molecular Psychiatry
Cell transplants may be a novel treatment for schizophrenia
Researchers from the School of Medicine at the University of Texas Health Science Center at San Antonio discovered that transplanting stem cells into the rat brain -- into a center called the hippocampus -- restored functions that are abnormal in schizophrenia.
National Institutes of Health, Hogg Foundation

Contact: Will Sansom
University of Texas Health Science Center at San Antonio

Public Release: 9-Sep-2013
Nature Biotechnology
Genome of elastomeric materials creates novel materials
A wide range of biologically inspired materials may now be possible by combining protein studies, materials science and RNA sequencing, according to an international team of researchers.
Office of Naval Research, National Institutes of Health

Contact: A'ndrea Elyse Messer
Penn State

Public Release: 9-Sep-2013
Proceedings of the National Academy of Sciences
Chemists find new way to put the brakes on cancer
Researchers from USC and NYU have developed a synthetic molecule, "protein domain mimetic," which targets the interaction between two proteins, called transcription factor-coactivator complex at the point where intracellular signaling cascade converges resulting in an up-regulation of genes that promote tumor progression.
National Science Foundation, National Institutes of Health

Contact: James Devitt
New York University

Public Release: 9-Sep-2013
EMBO Molecular Medicine
First animal model of adult-onset SMA sheds light on disease progression & treatment
A research team at Cold Spring Harbor Laboratory has used a recently developed technology they call TSUNAMI to create the first animal model of the adult-onset version of spinal muscular atrophy, a devastating motor-neuron illness.
National Institutes of Health, Muscular Dystrophy Association, Spinal Muscular Atrophy Foundation, St. Giles Foundation

Contact: Peter Tarr
Cold Spring Harbor Laboratory

Public Release: 9-Sep-2013
Health Affairs
ER visits after surgery: Study finds high rate among seniors & lots of variation among hospitals
Nearly one in five older adults who have common operations will end up in the emergency department within a month of their hospital stay, a new study finds -- a surprisingly high number found in the first national look at the issue. What's even more surprising? The wide variation between hospitals, in keeping their older surgery patients from needing emergency care after surgery. Some hospitals had four times the rate of others.
NIH/National Institute on Aging

Contact: Kara Gavin
University of Michigan Health System

Public Release: 9-Sep-2013
Journal of Clinical Investigation
JCI early table of contents for Sept. 9, 2013
This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, Sept. 9, 2013, in the JCI: Study identifies fibroblast growth factor 18 as an ovarian cancer biomarker, Insulin secretion disrupted by increased fatty acids, Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury, Retinal angiogenesis suppression through small molecule activation of p53, Perturbation of NK cell peripheral homeostasis accelerates prostate carcinoma metastasis
National Institutes of Health, The Julie Fund, MD Anderson SPORE, Wellcome Trust, UK diabetes project, Swiss National Science Foundation

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 8-Sep-2013
Nature Genetics
Researchers uncover genetic cause of childhood leukemia
For the first time, a genetic link specific to risk of childhood leukemia has been identified, according to a team of researchers from Memorial Sloan-Kettering Cancer Center, St. Jude Children's Research Hospital, University of Washington, and other institutions.
Starr Cancer Research Initiative, National Institutes of Health

Contact: Andrea Molinatti
Memorial Sloan-Kettering Cancer Center

Public Release: 8-Sep-2013
Team IDs 2 pathways through which chromosomes are rearranged
A research team has identified two pathways through which chromosomes are rearranged in mammalian cells. Preventing these rearrangements could conceivably prevent cancer in some people.
National Institutes of Health, UT Health Science Center San Antonio/Cancer Therapy & Research Center

Contact: Will Sansom
University of Texas Health Science Center at San Antonio

Public Release: 8-Sep-2013
Nature Biotechnology
Synthetic mRNA can induce self-repair and regeneration of the infarcted heart
A team of scientists at Karolinska Institutet and Harvard University has taken a major step towards treatment for heart attack, by instructing the injured heart in mice to heal by expressing a factor that triggers cardiovascular regeneration driven by native heart stem cells. The study, published in Nature Biotechnology, also shows that there was an effect on driving the formation of a small number of new cardiac muscle cells.
Moderna Therapeutics, AstraZeneca, National Institutes of Health, and others

Contact: Katarina Sternudd
Karolinska Institutet

Public Release: 6-Sep-2013
Advanced Materials
Drug patch treatment sees new breakthrough
This new flexible patch treatment can quicken drug delivery time while cutting waste, and can likely minimize side-effects in some cases, notable in vaccinations and in cancer therapy.
National Institutes of Health, Chapel Hill's University Cancer Research Fund

Contact: Steven Mackay
Virginia Tech

Public Release: 6-Sep-2013
Biophysical Journal
Research yields first detailed view of morphing Parkinson's protein
Researchers have taken detailed images and measurements of the morphing structure of a brain protein thought to play a role in Parkinson's disease, information that could aid the development of medications to treat the condition.
National Institutes of Health

Contact: Emil Venere
Purdue University

Public Release: 5-Sep-2013
Annals of Internal Medicine
Social media + behavior psychology leads to HIV testing, better health behaviors
A new UCLA study demonstrates that an approach that combines behavioral science with social media and online communities can lead to increased AIDS testing and improved health behaviors among men at risk of HIV infection. The approach is also applicable across a variety of diseases.
NIH/National Institute of Mental Health, and others

Contact: Enrique Rivero
University of California - Los Angeles Health Sciences

Public Release: 5-Sep-2013
Molecular beacons light path to cardiac muscle repair
Having a pure population of cardiac muscle cells is essential for avoiding tumor formation after transplantation, but has been technically challenging. Researchers at Emory and Georgia Tech have developed a method for purifying cardiac muscle cells from stem cell cultures using molecular beacons.
NIH/National Heart, Lung, and Blood Institute, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, National Science Foundation

Contact: Quinn Eastman
Emory Health Sciences

Public Release: 5-Sep-2013
Cell Reports
LSUHSC researchers develop new system to better study behavior, cell function
A team of researchers led by Charles D. Nichols, PhD, Associate Professor of Pharmacology at LSU Health Sciences Center New Orleans, has successfully translated a new technology to better study behaviors and cellular function to fruit flies. This powerful genetic tool allows scientists to selectively, rapidly, reversibly, and dose-dependently remotely control behaviors and physiological processes in the fly which shares a significant degree of similarity to humans and can model human diseases.
National Institutes of Health

Contact: Leslie Capo
Louisiana State University Health Sciences Center

Public Release: 5-Sep-2013
Molecular marker predicts patients most likely to benefit longest from 2 popular cancer drugs
Johns Hopkins scientists have identified a molecular marker called "Mig 6" that appears to accurately predict longer survival -- up to two years -- among patients prescribed two of the most widely used drugs in a class of anticancer agents called EGFR inhibitors.
NIH/National Cancer Institute, Flight Attendant Medical Research Institute

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 5-Sep-2013
Prion-like proteins drive several diseases of aging
Two leading neurology researchers have proposed a theory that could unify scientists' thinking about several neurodegenerative diseases and suggest therapeutic strategies to combat them.
NIH/National Institute on Aging, German Federal Ministry of Education and Research

Contact: Lisa Newbern
Emory Health Sciences

Public Release: 5-Sep-2013
Bulletin of the American Meteorological Society
Global warming has increased risk of record heat, say Stanford scientists
Researchers calculate that intense heat like that in the summer of 2012 is up to four times more likely to occur now than in pre-industrial America, when there was much less carbon dioxide in the atmosphere.
National Science Foundation, National Institutes of Health

Contact: Noah Diffenbaugh
Stanford University

Public Release: 5-Sep-2013
Some immune cells appear to aid cancer cell growth, U-M study finds
A new study from researchers at the University of Michigan Comprehensive Cancer Center found that a subset of immune cells, called myeloid derived suppressor cells, provide a niche where cancer stem cells survive.
NIH/National Cancer Institute, Ovarian Cancer Research Fund, Marsha Rivkin Center for Ovarian Cancer Research

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 5-Sep-2013
Inner-ear disorders may cause hyperactivity
Behavioral abnormalities are traditionally thought to originate in the brain. But a new study by researchers at Albert Einstein College of Medicine of Yeshiva University has found that inner-ear dysfunction can directly cause neurological changes that increase hyperactivity. The study, conducted in mice, also implicated two brain proteins in this process, providing potential targets for intervention. The findings were published today in the online edition of Science.
National Institutes of Health, Tourette Syndrome Association, Deutsche Forschungsgemeinschaft

Contact: Kim Newman
Albert Einstein College of Medicine

Public Release: 5-Sep-2013
Clinical Journal of the American Society of Nephrology
Study expands use of biomarker for early diagnosis of acute kidney injury
A biomarker test developed initially to identify early acute kidney injury (AKI) after surgery has been shown to successfully detect AKI in emergency room patients with a variety of urgent health issues. In a study published online Sept. 5 in the Clinical Journal of the American Society of Nephrology, the findings expand the overall utility and potential medical settings for using the test, according to researchers.
National Institutes of Health, Fundação Nacional para a Ciência e Tecnologia in Portugal

Contact: Nick Miller
Cincinnati Children's Hospital Medical Center

Public Release: 5-Sep-2013
Arteriosclerosis, Thrombosis, and Vascular Biology
New coating may reduce blood clot risk inside stents
A new stent coating may someday eliminate a common side effect of the treatment.
NIH/National Heart, Lung, and Blood Institute

Contact: Maggie Francis
American Heart Association

Public Release: 4-Sep-2013
American Journal of Physiology - Heart and Circulatory Physiology
Your finger's pulse holds the key to your heart's health
A University of Iowa physiologist has a new technique to measure the stiffness of the aorta, a common risk factor for heart disease. The procedure involves measuring the pulse in the finger or on the arm, combined with an individual's age and body mass index. Results are published in the American Journal of Physiology Heart and Circulatory Physiology.
National Institutes of Health, American Heart Association, University of Iowa

Contact: Richard Lewis
University of Iowa

Public Release: 4-Sep-2013
Circulation Research
Youthful stem cells from bone can heal the heart, Temple scientists report
Researchers at Temple University School of Medicine's Cardiovascular Research Center have discovered that when it comes to the regeneration of heart tissue, cortical bone-derived stem cells might do a better job than the heart's own stem cells. This finding challenges longstanding assumptions about which cells are the most effective at repairing damaged heart tissue after heart attacks.
National Institutes of Health

Contact: Jeremy Walter
Temple University Health System

Public Release: 4-Sep-2013
Mount Sinai receives NIH grant to increase colorectal cancer screenings in African Americans
Researchers at the Icahn School of Medicine at Mount Sinai have received a multi-year National Institutes of Health grant to determine factors which may influence why African Americans are less likely than others to receive colorectal cancer (CRC) screenings, despite having the highest CRC incidence and mortality of any ethnic/racial group in America.
National Institutes of Health

Contact: Press Office
The Mount Sinai Hospital / Mount Sinai School of Medicine

Showing releases 3351-3375 out of 3452.

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