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Key: Meeting M      Journal J      Funder F

Showing releases 3351-3375 out of 3799.

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Public Release: 15-Sep-2014
X-rays unlock a protein's SWEET side
Understanding just how sugar makes its way into the cell could lead to the design of better drugs for diabetes patients and an increase in the amount of fruits and vegetables farmers are able to grow. Stanford University researchers have recently uncovered one of these 'pathways' into the cell by piecing together proteins slightly wider than the diameter of a strand of spider silk.
US Department of Energy, National Institutes of Health, NIH/National Institute of General Medical Sciences

Contact: Tona Kunz
DOE/Argonne National Laboratory

Public Release: 15-Sep-2014
IU study: Combining epilepsy drug, morphine can result in less pain, lower opioid doses
Adding a common epilepsy drug to a morphine regimen can result in better pain control with fewer side effects. Moreover, the combination can reduce the dosage of the opioid needed to be effective, according to a team of pain researchers at Indiana University.
National Institutes of Health, Indiana Spinal Cord and Brain Injury Research Fund

Contact: Eric Schoch
Indiana University

Public Release: 15-Sep-2014
Cells simply avoid chromosome confusion
Reproductive cell division has evolved a simple, mechanical solution to avoid chromosome sorting errors. This natural safeguard prevents incorrect chromosome counts and misalignments that lead to infertility, miscarriage, or congenital conditions.
Wellcome Trust, National Institutes of Health, Packard Fellowship, Ludwig Institute for Cancer Research, Sidney Kimmel Foundation

Contact: Leila Gray
University of Washington Health Sciences/UW Medicine

Public Release: 15-Sep-2014
Proceedings of the National Academy of Sciences
Network measures predict neuropsychological outcome after brain injury
In research published online Sept. 15 in the Early Edition of the Proceedings of the National Academy of Sciences, scientists studied neurological patients with focal brain damage, and found that damage to six hub locations -- identified in a model developed at Washington University using resting state fMRI, functional connectivity analyses, and graph theory -- produced much greater cognitive impairment than damage to other locations.
National Institutes of Health, McDonnell Foundation, Simons Foundation, NIH/National Institutes of Mental Health

Contact: John Riehl
University of Iowa Health Care

Public Release: 15-Sep-2014
Proceedings of the National Academy of Sciences
Neuroscientists identify key role of language gene
Neuroscientists have found that a gene mutation that arose more than half a million years ago may be key to humans' unique ability to produce and understand speech.
Nancy Lurie Marks Family Foundation, Simons Foundation, National Institutes of Health, Wellcome Trust, Foundation pour la Recherche Medicale, Max Planck Society

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 15-Sep-2014
American Journal of Pathology
Predicting prostate cancer: Pitt-developed test identifies new methods for treatment
A genetic discovery out of the University of Pittsburgh School of Medicine is leading to a highly accurate test for aggressive prostate cancer and identifies new avenues for treatment.
National Institutes of Health, American Cancer Society, University of Pittsburgh Cancer Institute

Contact: Allison Hydzik
University of Pittsburgh Schools of the Health Sciences

Public Release: 15-Sep-2014
ASTRO's 56th Annual Meeting
Study adds to cancer-fighting promise of combined immunotherapy-radiation treatment
A study in mice implanted with breast and melanoma cancers adds to a growing body of evidence that highly focused radiation -- long thought to suppress immunity -- can actually help boost the immune system's fight against cancer when combined with a new kind of immune-enhancing drug.
American Association of Therapeutic Radiation Oncology, NIH/National Cancer Institute

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 15-Sep-2014
Advances in Nutrition
Vitamin E intake critical during 'the first 1,000 days'
Amid conflicting reports about the need for vitamin E and how much is enough, a new analysis published today suggests that adequate levels of this essential micronutrient are especially critical for the very young, the elderly, and women who are or may become pregnant.
National Institutes of Health

Contact: Maret Traber
Oregon State University

Public Release: 15-Sep-2014
American Journal of Psychiatry
Schizophrenia not a single disease but multiple genetically distinct disorders
New research shows that schizophrenia isn't a single disease but a group of eight genetically distinct disorders, each with its own set of symptoms. The finding could be a first step toward improved diagnosis and treatment for the debilitating psychiatric illness. The research at Washington University School of Medicine in St. Louis is reported online Sept. 15 in the American Journal of Psychiatry.
NIH/National Institute of Mental Health, Spanish Ministry of Science and Technology, R.L. Kirchstein National Research Award, and others

Contact: Elizabethe Holland Durando
Washington University School of Medicine

Public Release: 15-Sep-2014
Proceedings of the National Academy of Sciences
Cancer and the immune system: A double-edged sword
During cancer development, tumor cells decorate their surfaces with sugar compounds called glycans that are different from those found on normal, healthy cells. Researchers at the University of California, San Diego School of Medicine report that sialic acids at the tips of these cancer cell glycans are capable of engaging with immune system cells and changing the latter's response to the tumor -- for good and bad.
Swiss National Science Foundation, Samuel and Ruth Engelberg Cancer Research Institute, National Institutes of Health

Contact: Scott LaFee
University of California - San Diego

Public Release: 15-Sep-2014
American Journal of Psychiatry
To curb violent tendencies, start young
Aggressive children are less likely to become violent criminals or psychiatrically troubled adults if they receive intensive early intervention, say a new study based on more than two decades of research. The study from researchers at Duke and three other universities provides some of the strongest evidence yet that violent tendencies can be curbed.
NIH/National Institute of Mental Health, US Department of Education, NIH/National Institute on Drug Abuse

Contact: Alison Jones
Duke University

Public Release: 15-Sep-2014
Proceedings of the National Academy of Sciences
Slow to mature, quick to distract: ADHD study finds slower development of connections
A peek inside the brains of more than 750 children and teens reveals a key difference in brain architecture between those with attention deficit hyperactivity disorder and those without. Kids and teens with ADHD, a new study finds, lag behind others of the same age in how quickly their brains form connections within, and between, key brain networks.
National Institutes of Health, University of Michigan, John Templeton Foundation

Contact: Kara Gavin
University of Michigan Health System

Public Release: 15-Sep-2014
Clinical Cancer Research
New knowledge of genes driving bladder cancer points to targeted treatments
A collaborative study between researchers at the University of Colorado Cancer Center and the National Cancer Institute published today in the journal Clinical Cancer Research identifies BAP1 mutations in bladder cancer and also, independently, TERT mutations, implying two 'causes' of two distinct types of bladder cancer.
National Institutes of Health, NIH/National Cancer Institute-Intramural Support Program

Contact: Garth Sundem
University of Colorado Anschutz Medical Campus

Public Release: 15-Sep-2014
Journal of Studies on Alcohol and Drugs
Marijuana users who feel low get high
Adolescents and young adults who smoke marijuana frequently may attempt to manage negative moods by using the drug, according to a study in September's Journal of Studies on Alcohol and Drugs.
NIH/National Institute on Drug Abuse, NIH/National Institutes of Health

Contact: Erin Tornatore
Journal of Studies on Alcohol and Drugs

Public Release: 15-Sep-2014
Nature Chemical Biology
UK study identifies molecule that induces cancer-killing protein
A new study by University of Kentucky researchers has identified a novel molecule named Arylquin 1 as a potent inducer of Par-4 secretion from normal cells. Par-4 is a protein that acts as a tumor suppressor, killing cancer cells while leaving normal cells unharmed.
NIH/National Cancer Institute, NIH/National Center for Research Resources, UK Center for Clinical and Translational Science

Contact: Allison Perry
University of Kentucky

Public Release: 14-Sep-2014
Genes & Development
UNC researchers find final pieces to the circadian clock puzzle
UNC researchers discovered how two genes -- Period and Cryptochrome -- keep the circadian clocks in cells in proper rhythm with the 24-hour day. The finding has implications for drug development for various diseases including cancer and conditions such as jetlag and season affective disorder.
National Institutes of Health, Science Research Council, Academia Sinica in Taiwan

Contact: Mark Derewicz
University of North Carolina Health Care

Public Release: 14-Sep-2014
How an ancient vertebrate uses familiar tools to build a strange-looking head
In this study, investigator and scientific director Robb Krumlauf, Ph.D., and colleagues show that the sea lamprey Petromyzon marinus, a survivor of ancient jawless vertebrates, exhibits a pattern of gene expression that is reminiscent of its jawed cousins, who evolved much, much later.
Stowers Institute, National Institutes of Health

Contact: Kim Bland, Ph.D.
Stowers Institute for Medical Research

Public Release: 14-Sep-2014
Nature Neuroscience
Researchers find neural compensation in people with Alzheimer's-related protein
UC Berkeley researchers have found that the human brain is capable of a neural workaround that compensates for the buildup of beta-amyloid, a destructive protein associated with Alzheimer's disease. The findings could help explain how some older adults with beta-amyloid deposits in their brain retain normal cognitive function while others develop dementia.
NIH/National Institute on Aging, McKnight Foundation

Contact: Sarah Yang
University of California - Berkeley

Public Release: 14-Sep-2014
Nature Medicine
Muscular dystrophy: Repair the muscles, not the genetic defect
A potential way to treat muscular dystrophy directly targets muscle repair instead of the underlying genetic defect that usually leads to the disease.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH/National Institute of Neurological Disorders and Stroke

Contact: Laura Bailey
University of Michigan

Public Release: 14-Sep-2014
Nature: New drug blocks gene driving cancer growth
When active, the protein called Ral can drive tumor growth and metastasis in several human cancers including pancreatic, prostate, lung, colon and bladder. Unfortunately, drugs that block its activity are not available. A study published today in the journal Nature uses a novel approach to target the activation of these Ral proteins.
National Institutes of Health

Contact: Garth Sundem
University of Colorado Anschutz Medical Campus

Public Release: 12-Sep-2014
Cell Reports
Zebrafish model of a learning and memory disorder shows better treatment
Using a zebrafish model of a human genetic disease called neurofibromatosis, a team from the Perelman School of Medicine at the University of Pennsylvania has found that the learning and memory components of the disorder are distinct features that will likely need different treatment approaches.
NIH/National Heart, Lung and Blood, NIH/Institute National Institute of Mental Health, Department of Defense, FRAXA Research Foundation

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 12-Sep-2014
Journal of Bone and Mineral Research
USC researchers discover the healing power of 'rib-tickling'
Unlike salamanders, mammals can't regenerate lost limbs, but they can repair large sections of their ribs. In a new study in the Journal of Bone and Mineral Research, a team directed by USC Stem Cell researcher Francesca Mariani takes a closer look at rib regeneration in both humans and mice.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Cristy Lytal
University of Southern California - Health Sciences

Public Release: 12-Sep-2014
Proceedings of the National Academy of Sciences
New glaucoma culprit is found
In a unique study of human ocular cells, a multi-institution team led by a Northwestern University biomedical engineer has found that endothelial cells in Schlemm's canal -- important for draining fluid from the eye -- are stiffer in eyes with glaucoma than those in healthy eyes. The resulting increased flow resistance is responsible for the elevated pressure associated with glaucoma. Therapeutic strategies that alter the stiffness of these cells could lead to a cure for this debilitating disease.
National Institutes of Health, Bright Focus Foundation

Contact: Megan Fellman
Northwestern University

Public Release: 12-Sep-2014
Journal of Clinical Sleep Medicine
Sleep disorders widely undiagnosed in individuals with multiple sclerosis
In what may be the largest study of sleep problems among individuals with multiple sclerosis, researchers at UC Davis have found that widely undiagnosed sleep disorders may be at the root of the most common and disabling symptom of the disease: fatigue.
NIH/National Center for Advancing Translational Sciences, National Institutes of Health

Contact: Phyllis Brown
University of California - Davis Health System

Public Release: 11-Sep-2014
Journal of Neuroscience
Brain inflammation dramatically disrupts memory retrieval networks, UCI study finds
Brain inflammation can rapidly disrupt our ability to retrieve complex memories of similar but distinct experiences, according to UC Irvine neuroscientists Jennifer Czerniawski and John Guzowski.
National Institutes of Health

Contact: Tom Vasich
University of California - Irvine

Showing releases 3351-3375 out of 3799.

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