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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3351-3375 out of 3407.

<< < 130 | 131 | 132 | 133 | 134 | 135 | 136 | 137 > >>

Public Release: 30-Apr-2013
Proceedings of the National Academy of Sciences
Scientists find mutation driving pediatric brain tumors
A type of low-grade but sometimes lethal brain tumor in children has been found in many cases to contain an unusual mutation that may help to classify, diagnose and guide the treatment of the tumors, report scientists at Dana-Farber Cancer Institute.
Pediatric Low Grade Astrocytoma Foundation, National Institutes of Health

Contact: Anne Doerr
Dana-Farber Cancer Institute

Public Release: 30-Apr-2013
American Journal of Physiology - Gastrointestinal and Liver Physiology
Discovery helps explain how children develop rare, fatal disease
A team of biochemistry researchers at the University of Missouri has published conclusive scientific evidence that the gene ATP7A is essential for the dietary absorption of the nutrient copper. Their work with laboratory mice also provides a greater understanding of how this gene impacts Menkes disease as scientists search for a treatment.
National Institutes of Health

Contact: Christian Basi
University of Missouri-Columbia

Public Release: 30-Apr-2013
Journal of Adolescent Health
Teen girls less successful than boys at quitting meth in UCLA pilot research study
A UCLA-led study of adolescents receiving treatment for methamphetamine dependence has found that girls are more likely to continue using the drug during treatment than boys, suggesting that new approaches are needed for treating meth abuse among teen girls.
NIH/National Institute on Drug Abuse

Contact: Enrique Rivero
University of California - Los Angeles Health Sciences

Public Release: 30-Apr-2013
Nature Immunology
T cells rely on 'rheostat' to help ensure that the immune response matches the threat
A properly functioning immune system is a lesson in balance, providing protection against disease without attacking healthy tissue. Work led by St. Jude Children's Research Hospital scientists and published recently in Nature Immunology has identified a mechanism that helps T cells find that sweet spot where the strength of the immune response matches the threat.
National Institutes of Health, American-Lebanese-Syrian Associated Charities

Contact: Summer Freeman
St. Jude Children's Research Hospital

Public Release: 30-Apr-2013
Mast cells give clues in diagnosis, treatment of dengue
A protein produced by mast cells in the immune system may predict which people infected with dengue virus will develop life-threatening complications, according to researchers at Duke Medicine and Duke-National University of Singapore.
National Institutes of Health, National Medical Research Council of Singapore and the Duke-NUS Signature Research Program

Contact: Rachel Harrison
Duke University Medical Center

Public Release: 30-Apr-2013
Cancer Discovery
How some cancers 'poison the soil' to block metastasis
Cancer spread or metastasis can strike unprecedented fear in the minds of cancer patients. The "seed and the soil" hypothesis proposed by Stephen Paget in 1889 is now widely accepted to explain how cancer cells (seeds) are able to generate fertile soil (the microenvironment) in distant organs that promotes cancer's spread. However, this concept does not explain why some tumors do not spread or metastasize.
National Institutes of Health, Norwegian Cancer Society, Norwegian Research Council

Contact: Lauren Woods
Weill Cornell Medical College

Public Release: 30-Apr-2013
Annals of Emergency Medicine
Advancing emergency care for kids: Emergency physicians do it again
Most children with isolated skull fractures may not need to stay in the hospital, which finding has the potential to save the health care system millions of dollars a year. In addition, a new device more accurately estimates children's weights, leading to more precise drug dosing in the ER. Two studies published online this month in Annals of Emergency Medicine showcase some of the work emergency physicians are doing to improve care for children in the nation's emergency departments.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development

Contact: julie lloyd
American College of Emergency Physicians

Public Release: 30-Apr-2013
Estrogen fuels autoimmune liver damage
A Johns Hopkins Children's Center study in mice may help explain why women are more prone than men to a form of liver damage by implicating the female sex hormone estrogen in the development of autoimmune hepatitis.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Ekaterina Peshva
Johns Hopkins Medicine

Public Release: 30-Apr-2013
Stem Cells and Development
Identification of stem cells raises possibility of new therapies
Many diseases -- obesity, type 2 diabetes, muscular dystrophy -- are associated with fat accumulation in muscle. In essence, fat replacement causes the muscles to weaken and degenerate. Scientists at Wake Forest Baptist Medical Center have discovered the biological mechanism involved in this process, which could point the way to potential therapies.
NIH/National Institute on Aging, NIH/National Institute of Mental Health

Contact: Marguerite Beck
Wake Forest Baptist Medical Center

Public Release: 30-Apr-2013
Sleep duration associated with higher colorectal cancer risk
A new study is the first to report a significant positive association between long sleep duration and the development of colorectal cancer, especially among individuals who are overweight or snore regularly. The results raise the possibility that obstructive sleep apnea may contribute to cancer risk.
National Institutes of Health

Contact: Lynn Celmer
American Academy of Sleep Medicine

Public Release: 30-Apr-2013
Study finds possible alternative to bariatric weight loss surgery
An experimental procedure successfully tested in obese laboratory rats may provide a less-invasive alternative to bariatric weight-loss surgery. Scientists at Cincinnati Children's Hospital Medical Center used a catheter to redirect the flow of bile from the bile duct into the small intestine, producing the same metabolic and weight-loss benefits as bariatric surgeries such as gastric by-pass.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Ethicon Endo-Surgery

Contact: Nick Miller
Cincinnati Children's Hospital Medical Center

Public Release: 30-Apr-2013
Journal of Neuroscience
Neon exposes hidden ALS cells
A small group of neurons in the cortex play a big role in ALS (amyotrophic lateral sclerosis), a fatal disease. But the neurons have been difficult to study because they look so similar to others in the cortex. New research has isolated the brain's motor neurons that die in ALS and dressed them in a green fluorescent jacket. Now scientists can easily find them to study why they die and how to save them.
Les Turner ALS Foundation, NIH/National Institute of Neurological Disorders and Stroke, Wenske Foundation

Contact: Marla Paul
Northwestern University

Public Release: 30-Apr-2013
Clinical Cancer Research
Mayo Clinic finds experimental drug inhibits growth in all stages of common kidney cancer
Researchers at Mayo Clinic's campus in Florida have discovered a protein that is overly active in every human sample of kidney cancer they examined. They also found that an experimental drug designed to block the protein's activity significantly reduced tumor growth in animals when used alone. Combining it with another drug already used to treat the cancer improved the effectiveness of both.
NIH/National Cancer Institute

Contact: Kevin Punsky
Mayo Clinic

Public Release: 30-Apr-2013
Tiny worm sheds light on giant mystery about neurons
Scientists at the Oklahoma Medical Research Foundation studying neurons in Caenorhabditis elegans have found a gene, unc-16, that serves as a gatekeeper, restricting the flow of cellular organelles from the cell body to the axon. Organelles clogging the axon could potentially interfere with neuronal signaling or cause the axon to degenerate, leading to neurodegenerative disorders. This research is published in the May 2013 Genetics Society of America's journal GENETICS.
National Institutes of Health, Oklahoma Center for the Advancement of Science

Contact: Phyllis Edelman
Genetics Society of America

Public Release: 29-Apr-2013
Study explains what triggers those late-night snack cravings
A study co-authored by an Oregon Health and Science University researcher finds that the circadian system increases hunger and cravings for sweet, starchy and salty foods in the evenings. Eating higher-calorie foods in the evening can be counterproductive if weight loss is a goal since the human body handles nutrients differently depending on the time of day.
National Institutes of Health, NASA

Contact: Mirabai Vogt
Oregon Health & Science University

Public Release: 29-Apr-2013
Nature Communications
Silicone liquid crystal stiffens with repeated compression
Rice University scientists find liquid crystalline silicone stiffens significantly when compressed repeatedly for hours on end. The discovery may lead to new strategies for self-healing materials or biocompatible materials that mimic human tissues.
National Science Foundation, NIH/National Institute of Allergy and Infectious Diseases, Welch Foundation

Contact: Mike Williams
Rice University

Public Release: 29-Apr-2013
Proceedings of the National Academy of Sciences
Scripps Research Institute scientists discover how a protein finds its way
Scientists from the Florida campus of the Scripps Research Institute have uncovered how an enzyme co-factor can bestow specificity on a class of proteins with otherwise nonspecific biochemical activity.
National Institutes of Health, American Heart Association

Contact: Eric Sauter
Scripps Research Institute

Public Release: 29-Apr-2013
Journal of Clinical Investigation
Rare, lethal childhood disease tracked to protein
Scientists have identified how a defective protein plays a central role in a rare, lethal childhood disease known as giant axonal neuropathy, or GAN. GAN is an extremely rare and untreatable genetic disorder that strikes the central and peripheral nervous systems of young children.
NIH/National Institute of General Medical Sciences, Hannah's Hope Fund

Contact: Marla Paul
Northwestern University

Public Release: 29-Apr-2013
JAMA Internal Medicine
Surgery for nonfatal skin cancers might not be best for elderly patients
Surgery is often recommended for skin cancers, but older, sicker patients can endure complications as a result and may not live long enough to benefit from the treatment.
NIH/National Center for Research Resources, NIH/National Institute of Arthritis and Musculoskeletal and Skin

Contact: Elizabeth Fernandez
University of California - San Francisco

Public Release: 29-Apr-2013
Nature Photonics
'Super-resolution' microscope possible for nanostructures
Researchers have found a way to see synthetic nanostructures and molecules using a new type of super-resolution optical microscopy that does not require fluorescent dyes, representing a practical tool for biomedical and nanotechnology research.
National Science Foundation, National Institutes of Health, Defense Advanced Research Projects Agency

Contact: Emil Venere
Purdue University

Public Release: 29-Apr-2013
JAMA Internal Medicine
Antidepressants linked with increased risks after surgery
Selective serotonin reuptake inhibitors (SSRIs) -- among the most widely prescribed antidepressant medications -- are associated with increased risk of bleeding, transfusion, hospital readmission and death when taken around the time of surgery, according to an analysis led by researchers at UC San Francisco and Baystate Medical Center in Springfield, Mass.
NIH/National Heart, Lung and Blood Institute

Contact: Juliana Bunim
University of California - San Francisco

Public Release: 29-Apr-2013
Proceedings of the National Academy of Sciences
Study identifies key shift in the brain that creates drive to overeat
A team of American and Italian neuroscientists has identified a cellular change in the brain that accompanies obesity. The findings could explain the body's tendency to maintain undesirable weight levels, rather than an ideal weight, and identify possible targets for pharmacological efforts to address obesity. "This study identifies a mechanism for the body's ongoing tendency to return to the heavier weight," said Indiana University neuroscientist Ken Mackie.
National Institutes of Health, Compagnia di San Paolo

Contact: Liz Rosdeitcher
Indiana University

Public Release: 29-Apr-2013
Cat and mouse: A single gene matters
A Northwestern University study involving olfactory receptors provides evidence that a single gene is necessary for a mouse to avoid a cat. A research team has shown that removing one olfactory receptor from mice can have a profound effect on their behavior. The gene, called TAAR4, encodes a receptor that responds to a chemical that is enriched in the urine of carnivores. While normal mice innately avoid the scent marks of predators, mice lacking the TAAR4 receptor do not.
NIH/National Institute on Deafness and Other Communication Disorders, Whitehall Foundation, Brain Research Foundation

Contact: Megan Fellman
Northwestern University

Public Release: 29-Apr-2013
Scientific Reports
NYU and NYU Langone researchers devise method for enhancing CEST MRI
Researchers at NYU and NYU Langone Medical Center have created a novel way to enhance MRI by reducing interference from large macromolecules that can often obscure images generated by current chemical exchange saturation transfer (CEST) methods.
National Institutes of Health, National Science Foundation

Contact: James Devitt
New York University

Public Release: 29-Apr-2013
Proceedings of the National Academy of Sciences
Big data analysis identifies prognostic RNA markers in a common form of breast cancer
An analysis that integrates three large sets of genomic data available through The Cancer Genome Atlas has identified 37 RNA molecules that might predict survival in patients with the most common form of breast cancer. The study analyzed large masses of data from 466 cases of the most common type of breast cancer and provides the first prognostic signature in cancer composed of both mRNA and microRNA.
NIH/National Cancer Institute, Italian Association for Cancer Research

Contact: Darrell E. Ward
Ohio State University Wexner Medical Center

Showing releases 3351-3375 out of 3407.

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