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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3376-3400 out of 3531.

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Public Release: 16-Dec-2013
PLOS Pathogens
WSU scientists find burglary-ring-like mechanism in lethal 'Contagion' virus
A team of scientists from Washington State University has discovered how one of the planet's most deadly known viruses employs burglary-ring-like teamwork to infiltrate the human cell. Nipah virus is so menacing that the nation's top infectious disease experts served as consultants in the filmmaking of the 2011 medical thriller, "Contagion," which is based on a global Nipah outbreak.
National Institutes of Health

Contact: Hector Aguilar-Carreno
Washington State University

Public Release: 16-Dec-2013
Nature Genetics
Penn-led team reduces toxicity associated with Lou Gehrig's disease in animal models
Amyotrophic lateral sclerosis, better known as Lou Gehrig's disease, is a devastating illness that gradually robs sufferers of muscle strength and eventually causes a lethal, full-body paralysis. Working with a powerful fruit fly model of the disease, University of Pennsylvania researchers and colleagues reduced disease toxicity and slowed the dysfunction of neurons. Their discoveries offer the possibility of a new strategy for treating ALS.
National Institutes of Health, Howard Hughes Medical Institute, Packard Center for Amyotrophic Lateral Sclerosis, and others

Contact: Katherine Unger Baillie
University of Pennsylvania

Public Release: 16-Dec-2013
International Journal of General Medicine
Regenstrief and IU investigators identify first biomarker linked to delirium duration
Researchers from the Regenstrief Institute and the Indiana University Center for Aging Research have identified the first biomarker that appears to be linked to the duration of delirium. This novel role for S100-beta as a biomarker for delirium duration in critically ill patients may have important implications for refining future delirium treatment in intensive care unit patients.
NIH/National Institute on Aging, NIH/National Institute of Mental Health

Contact: Cindy Fox Aisen
Indiana University

Public Release: 16-Dec-2013
Health care costs steadily increase with body mass
According to a study published in the journal Obesity, health care costs increase in parallel with body mass measurements, even beginning at a recommended healthy weight.
Centers for Disease Control, NIH/National Institute for Occupational Safety and Health

Contact: Rachel Harrison
Duke University Medical Center

Public Release: 16-Dec-2013
Icahn School of Medicine at Mount Sinai garners $6 million NIH grant for concussion research
The Brain Injury Research Center of Mount Sinai has received a four-year, $6 million grant to study traumatic brain injuries in civilians.
National Institutes of Health

Contact: Sid Dinsay
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 16-Dec-2013
Nature Immunology
Scientists identify molecular biomarkers of vaccine immunity
Scientists at Emory Vaccine Center have taken an important step toward making a "vaccine gene chip," by comparing the molecular signatures induced by five very different vaccines in the immune systems of human volunteers.
NIH/National Institute of Allergy and Infectious Diseases, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Georgia Research Alliance

Contact: Holly Korschun
Emory Health Sciences

Public Release: 16-Dec-2013
Attention, Perception, & Psychophysics
Life's not a squeeze for pregnant women
Despite their changed body size, pregnant women are just as good as other people at judging whether they are able to fit through openings, such as doorways, or not. This is thanks to a process called perceptual-motor recalibration that helps people to adjust their spatial awareness of their environment based on changes in their body's size and abilities, say researchers in the US. Their study is published in Springer's journal Attention, Perception, & Psychophysics.
NIH/National Institute of Health and Human Development

Contact: Franziska Hornig

Public Release: 16-Dec-2013
Journal of Children's Services
5 effective parenting programs to reduce problem behaviors in children
University of Washington researchers evaluated about 20 parenting programs and found five that are especially effective at helping parents and children at all risk levels avoid adolescent behavior problems that affect not only individuals, but entire communities.
NIH/National Institute on Drug Abuse

Contact: Molly McElroy
University of Washington

Public Release: 16-Dec-2013
Journal of Clinical Investigation
Gene variant exacerbates inflammatory arthritis in mice
University of Utah researchers have discovered a naturally occurring genetic variation in mice that predisposes carriers toward developing severe, inflammatory arthritis.
National Institutes of Health, Arthritis Foundation

Contact: Julie Kiefer
University of Utah Health Sciences

Public Release: 16-Dec-2013
Frontiers in Behavioral Neuroscience
Wake Forest Baptist researchers study alcohol addiction using optogenetics
Wake Forest Baptist Medical Center researchers are gaining a better understanding of the neurochemical basis of addiction with a new technology called optogenetics.
National Institutes of Health

Contact: Bonnie Davis
Wake Forest Baptist Medical Center

Public Release: 16-Dec-2013
JAMA Internal Medicine
Physicians who prefer hospice care for themselves more likely to discuss it with patients
Although the vast majority of physicians participating in a multiregional study indicated that they would personally enroll in hospice care if they received a terminal cancer diagnosis, less than one-third would discuss hospice care early in the course of treating a terminally ill cancer patient.
NIH/National Cancer Institute, US Department of Veterans Affairs

Contact: Kristen Chadwick
Massachusetts General Hospital

Public Release: 16-Dec-2013
Journal of General Physiology
Tweaking energy consumption to combat muscle wasting and obesity
Using a new technique to evaluate working muscles in mice, researchers have uncovered physiological mechanisms that could lead to new strategies for combating metabolism-related disorders like muscle wasting and obesity.
National Institutes of Health, VA Merit Review Program, Carver Trust, Fraternal Order of Eagles

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 16-Dec-2013
Schizophrenia Bulletin
Heavy marijuana users have abnormal brain structure and poor memory
Teens who were heavy marijuana users had abnormal changes in their brains related to memory and performed poorly on memory tasks, reports a new study. The brain abnormalities and memory problems were observed in the subjects' early twenties, two years after they stopped smoking marijuana, possibly indicating long-term effects. Memory-related structures in their brains appeared to shrink. The younger drug abuse starts, the more abnormal the brain appeared. The marijuana-related brain abnormalities look similar to schizophrenia-related brain abnormalities.
NIH/National Institute of Mental Health, NIH/National Institute on Drug Abuse

Contact: Marla Paul
Northwestern University

Public Release: 16-Dec-2013
Proceedings of the National Academy of Sciences
Vanderbilt study: Ancient chemical bond may aid cancer therapy
A chemical bond discovered by Vanderbilt University scientists that is essential for animal life and which hastened the 'dawn of the animal kingdom' could lead to new therapies for cancer and other diseases.
National Institutes of Health

Contact: Craig Boerner
Vanderbilt University Medical Center

Public Release: 16-Dec-2013
Journal of Clinical Investigation
A mouse model to evaluate potential age-promoting compounds
Recently, a mouse strain (p16LUC mice) was developed that can be used to evaluate the transcription of p16INK4, which is increasingly expressed during aging and in age-associated diseases. In this issue of the Journal of Clinical Investigation, Norman Sharpless and colleagues at the University of North Carolina evaluated potential age-promoting compounds, including arsenic, a high-fat diet, UV light, and cigarette smoke in p16LUC mice.
National Institutes of Health, Howard Hughes Medical Institute

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 15-Dec-2013
Nature Medicine
Pitt study: Lung lesions of TB variable, independent whether infection is active or latent
The lung lesions in an individual infected with tuberculosis are surprisingly variable and independent of each other, despite whether the patient has clinically active or latent disease, according to a new animal study led by researchers at the University of Pittsburgh School of Medicine. The findings, published online today in Nature Medicine, could point the way to new vaccines to prevent the hard-to-treat infection.
Bill & Melinda Gates Foundation, Otis Childs Trust, Children's Hospital of Pittsburgh Foundation, National Institutes of Health, Howard Hughes Medical Institute, Burroughs Wellcome Foundation, and others

Contact: Anita Srikameswaran
University of Pittsburgh Schools of the Health Sciences

Public Release: 13-Dec-2013
Journal of Biological Chemistry
UI researcher studies evolution on the molecular level
UI researchers describe the evolution of various forms of the enzyme "dihydrofolate reductase" as it occurred from bacteria to humans. Their paper, which appears in the Dec. 13 issue of the Journal of Biological Chemistry, may prove useful to scientists in the design of future drugs and catalysts.
National Science Foundation, National Institutes of Health

Contact: Gary Galluzzo
University of Iowa

Public Release: 13-Dec-2013
UTHealth named one of nation's NIH stroke network centers
The University of Texas Health Science Center at Houston has been named one of 25 regional stroke centers by the National Institutes of Health and the only one in Texas.
National Institutes of Health

Contact: Deborah Lake
University of Texas Health Science Center at Houston

Public Release: 13-Dec-2013
Nature Neuroscience
No 2 people smell the same
With about 400 odor receptors in the human nose, and more than 900,000 variations on the genes that build those receptors, it would appear that no two humans smell things the same way. Between any two individuals, they may vary by at least 30 percent in the population of receptors they have, according to a Duke University team led by Hiroaki Matsunami.
National Institutes of Health

Contact: Karl Leif Bates
Duke University

Public Release: 13-Dec-2013
American Journal of Kidney Diseases
UCSF research finds new link between obesity, early decline in kidney function
A new UCSF-led study of nearly 3,000 individuals links obesity to the development of kidney disease.
NIH/National Institute of Diabetes and Digestive and Kidney Disease, NIH/National Institute on Minority Health and Health Disparities

Contact: Peter Farley
University of California - San Francisco

Public Release: 13-Dec-2013
Journal of Infectious Diseases
Plaque composition, immune activation explain cardiovascular risk in HIV-infected women
A Massachusetts General Hospital research team has discovered a possible mechanism behind the elevated risk of cardiovascular disease in women infected with HIV, a risk even higher than that of HIV-infected men.
Bristol-Myers Squibb, National Institutes of Health

Contact: Cassandra Aviles
Massachusetts General Hospital

Public Release: 13-Dec-2013
Advanced Functional Materials
Duke engineers make strides toward artificial cartilage
A Duke research team has developed a better recipe for synthetic replacement cartilage in joints, calling for a newly designed durable hydrogel to be poured over a three-dimensional fabric "scaffold."
National Institutes of Health, National Science Foundation, Arthritis Foundation, Collaborative Research Center, AO Foundation

Contact: Ken Kingery
Duke University

Public Release: 13-Dec-2013
Proceedings of the National Academy of Sciences
Breakthrough could lead to protection from fatal infections
Researchers at UTMB have found a way to protect against what can be a fatal rickettsial infection.
National Institutes of Health

Contact: Raul Reyes
University of Texas Medical Branch at Galveston

Public Release: 13-Dec-2013
Pathogen study explores blocking effect of E. coli O157:H7 protein
Philip Hardwidge, associate professor at the College of Veterinary Medicine at Kansas State University, is studying how pathogens such as E. coli use proteins to block a host's innate immune system. His work is being supported by a multiyear grant from the National Institutes of Health.
National Institutes of Health

Contact: Philip Hardwidge
Kansas State University

Public Release: 13-Dec-2013
2013 CTRC-AACR San Antonio Breast Cancer Symposium
New presurgery treatment combination more effective for women with triple-negative breast cancer
Adding the chemotherapy drug carboplatin and/or the antibody therapy bevacizumab to standard presurgery chemotherapy increased the number of women with triple-negative breast cancer who had no residual cancer detected at surgery, according to results of a randomized, phase II clinical trial presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.
National Institutes of Health, Genentech, the Breast Cancer Research Foundation

Contact: Jeremy Moore
American Association for Cancer Research

Showing releases 3376-3400 out of 3531.

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