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Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3376-3400 out of 3684.

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Public Release: 30-May-2014
Lab on a Chip
Building a better blood vessel
The tangled highway of blood vessels that twists and turns inside our bodies, delivering essential nutrients and disposing of hazardous waste to keep our organs working properly has been a conundrum for scientists trying to make artificial vessels from scratch. Now a team from Brigham and Women's Hospital has made headway in fabricating blood vessels using a three-dimensional bioprinting technique.
National Institutes of Health

Contact: Marjorie Montemayor-Quellenberg
Brigham and Women's Hospital

Public Release: 30-May-2014
Nature Communications
For the first time in the lab, researchers see stem cells take key step toward development
The gap between stem cell research and regenerative medicine just became a lot narrower, thanks to a new technique that coaxes stem cells to take the first step to specialization for the first time in a laboratory. University of Illinois researchers demonstrated that not only is it possible for mouse embryonic stem cells to form three distinct germ layers in the lab, but also that it requires correct timing, chemical factors and mechanical environment.
National Institutes of Health

Contact: Liz Ahlberg
University of Illinois at Urbana-Champaign

Public Release: 30-May-2014
Food and Chemical Toxicology
Compounds in saliva and common body proteins may fend off DNA-damaging chemicals
A compound in saliva, along with common proteins in blood and muscle, may protect human cells from powerful toxins in tea, coffee and liquid smoke flavoring, according to results of a new study led by investigators at the Johns Hopkins Kimmel Cancer Center.
NIH/National Cancer Institute

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 30-May-2014
Study explains how green tea could reduce pancreatic cancer risk
New study explains how green tea changed the metabolism of pancreatic cancer cells, opening a new area in cancer-fighting research.
National Institutes of Health, Hirshberg Foundation for Pancreatic Cancer Research

Contact: Laura Mecoy
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed)

Public Release: 30-May-2014
Research details how developing neurons sense a chemical cue
New structural images help explain how young neurons make the right connections, showing how a signal, Netrin-1, interacts with specific receptors that tell neurons in which direction to reach.
NIH/National Institute of General Medical Sciences, National Institutes of Health

Contact: Zach Veilleux
Rockefeller University

Public Release: 30-May-2014
ASCO 50th Annual Meeting
Radiation for prostate cancer linked to secondary cancers, study finds
Among men treated for prostate cancer, those who received radiation therapy were more likely to develop bladder or rectal cancer, according to a new study from the University of Michigan Comprehensive Cancer Center.
National Institutes of Health

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 30-May-2014
JAX cancer researchers awarded NCI 'provocative questions' grants
Jackson Laboratory Assistant Professors Jennifer Trowbridge, Ph.D., and Chengkai Dai, M.D., Ph.D., have each received new federal research grants through a funding mechanism designed to address 'provocative questions' about cancer set out by the National Cancer Institute.
NIH/National Cancer Institute

Contact: Joyce Peterson
Jackson Laboratory

Public Release: 30-May-2014
ASCO 50th Annual Meeting
New drug treatment helps prevent early menopause in breast cancer patients
Among young women treated for breast cancer, one of the most distressing side effects of chemotherapy is early menopause. But a major clinical trial has found that the risk of early menopause can be significantly reduced by adding a drug called goserelin to the chemotherapy regimen. Also, women who took goserelin were more likely to get pregnant and deliver a healthy baby.
NIH/National Cancer Institute

Contact: Jim Ritter
Loyola University Health System

Public Release: 29-May-2014
UH part of $7.5 million NIH clinical trial on nearsightedness in children
The University of Houston is part of a National Institutes of Health study to determine whether commercially available, soft bifocal contact lenses slow the progression of nearsightedness in children. Investigators at UH and The Ohio State University Colleges of Optometry were awarded grants from the National Eye Institute, worth approximately $7.5 million. The BLINK Study is a multicenter randomized clinical trial that will follow nearly 300 children over the course of three years.
NIH/National Eye Institute

Contact: Lisa Merkl
University of Houston

Public Release: 29-May-2014
New England Journal of Medicine
Mechanisms of ibrutinib resistance identified in chronic lymphocytic leukemia
A new study has discovered how resistance develops in patients taking ibrutinib, a new and highly effective drug for the treatment of chronic lymphocytic leukemia.
NIH/National Cancer Institute

Contact: Amanda Harper
Ohio State University Wexner Medical Center

Public Release: 29-May-2014
Journal of Exposure Science and Environmental Epidemiology
Study: Baltimore hookah bars contain elevated levels of carbon monoxide and air nicotine
In an analysis of air quality in seven Baltimore waterpipe bars, commonly known as hookah bars, researchers found that airborne particulate matter and carbon monoxide exceeded concentrations previously measured in public places that allowed cigarette smoking and that air nicotine was markedly higher than in smoke-free establishments.
NIH/National Heart, Lung, and Blood Institute

Contact: Asim Khan
Johns Hopkins University Bloomberg School of Public Health

Public Release: 29-May-2014
Molecular Cell
Penn study shows how misfolded proteins are selected for disposal
Researchers have identified a protein recycling pathway in mammalian cells that removes misfolded proteins. They also demonstrated this pathway's role in protecting against neurodegenerative diseases in an animal model.
NIH/National Cancer Institute, NIH/National Institute of General Medical Sciences

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 29-May-2014
Scripps Research Institute scientists win $13 million grant in AIDS vaccine effort
A team led by scientists at The Scripps Research Institute has received a grant of more than $13 million from the National Institute of Allergy and Infectious Disease of the National Institutes of Health to study antibodies to the human immunodeficiency virus (HIV) -- which will play an essential role in the creation of any effective vaccine against HIV.
NIH/National Institute of Allergy and Infectious Disease

Contact: Mika Ono
Scripps Research Institute

Public Release: 29-May-2014
Cerebral Cortex
Neural transplant reduces absence epilepsy seizures in mice
New research from North Carolina State University pinpoints the areas of the cerebral cortex that are affected in mice with absence epilepsy and shows that transplanting embryonic neural cells into these areas can alleviate symptoms of the disease by reducing seizure activity.
National Institutes of Health

Contact: Tracey Peake
North Carolina State University

Public Release: 29-May-2014
Angewandte Chemie
UNL team explores new approach to HIV vaccine
UNL scientists are pursuing a promising new approach to a live attenuated HIV-1 vaccine, using a genetically modified form of the HIV virus.
National Institutes of Health, NIH/National Institute of Allergy and Infectious Diseases

Contact: Jiantao Guo
University of Nebraska-Lincoln

Public Release: 29-May-2014
Engineering a better way to rebuild bone inside the body
A new technology under development at the Georgia Institute of Technology could one day provide more efficient delivery of the bone regenerating growth factors with greater accuracy and at a lower cost.
National Institutes of Health, National Science Foundation

Contact: Brett Israel
Georgia Institute of Technology

Public Release: 29-May-2014
SLEEP 2014
Family support may improve adherence to CPAP therapy for sleep apnea
A new study suggests that people with obstructive sleep apnea who are single or have unsupportive family relationships may be less likely to adhere to continuous positive airway pressure therapy.
NIH/National Heart, Lung, and Blood Institute

Contact: Lynn Celmer
American Academy of Sleep Medicine

Public Release: 29-May-2014
Fertility and Sterility
Stress degrades sperm quality
Psychological stress is harmful to sperm and semen quality, affecting its concentration, appearance, and ability to fertilize an egg, according to a study led by researchers Columbia University's Mailman School of Public Health and Rutgers School of Public Health. Results are published online in the journal Fertility and Sterility.
NIH/National Institute of Environmental Health Sciences

Contact: Timothy S. Paul
Columbia University's Mailman School of Public Health

Public Release: 29-May-2014
Biology of Reproduction
Zinc deficiency before conception disrupts fetal development
Female mice deprived of dietary zinc for a relatively short time before conception experienced fertility and pregnancy problems and had smaller, less-developed fetuses than mice that ingested zinc during the same times, according to researchers in Penn State's College of Agricultural Sciences.
National Institutes of Health

Contact: A'ndrea Elyse Messer
Penn State

Public Release: 29-May-2014
Journal of American Society of Nephrology
Reduced kidney function associated with higher risk of renal and urothelial cancer
Researchers who investigated the level of kidney function and subsequent cancer risk in more than one million adults have found that reduced glomerular filtration rate -- a key measure of reduced kidney function and chronic kidney disease -- is an independent risk factor for renal and urothelial cancer but not other cancer types.
National Institutes of Health, NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Linda Aagard
University of Utah Health Sciences

Public Release: 29-May-2014
Unprecedented detail of intact neuronal receptor offers blueprint for drug developers
Biologists at Cold Spring Harbor Laboratory report today that they have succeeded in obtaining an unprecedented view of a type of brain-cell receptor that is implicated in a range of neurological illnesses, including Alzheimer's disease, Parkinson's disease, depression, schizophrenia, autism, and ischemic injuries associated with stroke. The team's atomic-level picture of the intact NMDA receptor should serve as template and guide for the design of therapeutic compounds.
National Institutes of Health, Mirus Research Award, Robertson Research Fund of Cold Spring Harbor Laboratory

Contact: Jaclyn Jansen
Cold Spring Harbor Laboratory

Public Release: 29-May-2014
Journal of the American Society of Nephrology
Reduced kidney function associated with higher risk of renal and urothelial cancer
A key measure of reduced kidney function and chronic kidney disease -- reduced glomerular filtration rate -- is an independent risk factor for renal and urothelial cancer, according to a study published online today in the Journal of the American Society of Nephrology.
National Institutes of Health

Contact: Cyrus Hedayati
Kaiser Permanente

Public Release: 29-May-2014
Cancer Cell
Melanoma of the eye caused by 2 gene mutations
Researchers at the University of California, San Diego School of Medicine have identified a therapeutic target for treating the most common form of eye cancer in adults. They have also, in experiments with mice, been able to slow eye tumor growth with an existing FDA-approved drug.
National Institutes of Health, California Institute for Regenerative Medicine

Contact: Scott LaFee
University of California - San Diego

Public Release: 29-May-2014
Cell Reports
Lost in translation?
In any animal's lifecycle, the shift from egg cell to embryo is a critical juncture that requires a remarkably dynamic process that ultimately transforms a differentiated, committed oocyte to a totipotent cell capable of giving rise to any cell type in the body. The lab of Whitehead Member Terry Orr-Weaver conducted perhaps the most comprehensive look yet at changes in translation and protein synthesis during a developmental change, using the oocyte-to-embryo transition in Drosophila as a model system.
National Institutes of Health, American Cancer Society, Alexander von Humboldt Foundation

Contact: Matt Fearer
Whitehead Institute for Biomedical Research

Public Release: 28-May-2014
Health Psychology
Negative social interactions increase hypertension risk in older adults
Keeping your friends close and your enemies closer may not be the best advice if you are 50 or older. New research from Carnegie Mellon University's Rodlescia Sneed and Sheldon Cohen shows that unpleasant or demanding interpersonal encounters increase hypertension risk among older adults. Published in the American Psychological Association's Health Psychology Journal, the study provides some of the first concrete evidence that negative social interactions not only influence psychological well-being but also physical health -- in this case, blood pressure levels.
NIH/National Center for Complementary and Alternative Medicine

Contact: Shilo Rea
Carnegie Mellon University

Showing releases 3376-3400 out of 3684.

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