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Key: Meeting M      Journal J      Funder F

Showing releases 3401-3425 out of 3512.

<< < 132 | 133 | 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 > >>

Public Release: 12-Nov-2013
Mayo Clinic: Researchers to study body's defense system to find new treatments for Alzheimer's
Researchers at Mayo Clinic in Florida, the University of Florida in Gainesville, and the Institute for Systems Biology in Seattle have received a $7.5 million grant from the National Institutes of Health to take a new and more expanded approach to identifying drug targets to treat and possibly prevent Alzheimer's disease.
National Institutes of Health

Contact: Kevin Punsky
punsky.kevin@mayo.edu
904-953-2299
Mayo Clinic

Public Release: 12-Nov-2013
Neuroscience 2013
Using morphine after abdominal surgery may prolong pain, CU-Boulder researchers find
Using morphine to fight the pain associated with abdominal surgery may paradoxically prolong a patient's suffering, doubling or even tripling the amount of time it takes to recover from the surgical pain, according to researchers at the University of Colorado Boulder.
National Institutes of Health

Contact: Peter Grace
Peter.Grace@colorado.edu
University of Colorado at Boulder

Public Release: 12-Nov-2013
EMBO Journal
Wayne State researchers discover specific inhibitor for rheumatoid arthritis treatment
Researchers from Wayne State University and Northwestern University have contributed to an important discovery in the inflammatory stress mechanism and specific inhibitor for the treatment of rheumatoid arthritis.
National Institutes of Health, American Heart Association

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research

Public Release: 12-Nov-2013
Neuropsychology
Johns Hopkins research may improve early detection of dementia
Using scores obtained from cognitive tests, Johns Hopkins researchers think they have developed a model that could help determine whether memory loss in older adults is benign or a stop on the way to Alzheimer's disease.
NIH/National Institute of Mental Health

Contact: Stephanie Desmon
sdesmon1@jhmi.edu
410-955-8665
Johns Hopkins Medicine

Public Release: 12-Nov-2013
Molecular Cancer Therapeutics
Controlling the hormonal environment in endometrial cancer sensitizes tumors to PARP inhibitors
Modulating the hormonal environment in which endometrial cancers grow could make tumors significantly more sensitive to a new class of drugs known as PARP inhibitors.
Concern Foundation, NIH/National Cancer Institute, UCLA's Scholars in Translational Medicine Program

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-794-0777
University of California - Los Angeles Health Sciences

Public Release: 12-Nov-2013
Neuroscience 2013
Mindfulness inhibits implicit learning -- the wellspring of bad habits
Being mindful appears to help prevent the formation of bad habits, but perhaps good ones too. Behavioral and neuroimaging studies suggest that mindfulness can undercut the automatic learning processes, such as implicit learning. "Our theory is that one learns habits -- good or bad -- implicitly, without thinking about them," says author Chelsea Stillman. "We wanted to see if mindfulness impeded implicit learning."
National Institutes of Health

Contact: Karen Mallet
km463@georgetown.edu
Georgetown University Medical Center

Public Release: 11-Nov-2013
Proceedings of the National Academy of Sciences
New look identifies crucial clumping of diabetes-causing proteins
Subtle differences in the shape of proteins protect some and endanger others. "All mammals make this same protein called amylin, and it only differs a little bit from species to species," says Martin Zanni, a University of Wisconsin–Madison chemistry professor. "The mammals that get type 2 diabetes, their amylin proteins aggregate in the pancreas into plaque that kills the cells around them. As a result, you can't make insulin."
National Institutes of Health

Contact: Martin Zanni
zanni@chem.wisc.edu
608-262-4783
University of Wisconsin-Madison

Public Release: 11-Nov-2013
Molecular Biology and Evolution
Penn team elucidates evolution of bitter taste sensitivity
People often have strong negative reactions to bitter substances, which, though found in healthful foods like vegetables, can also signify toxicity. For this reason, the ability to sense bitterness likely played an important role in human evolution. A new study by University of Pennsylvania scientists suggests that a genetic mutation that makes certain people sensitive to the taste of a bitter compound appears to have been advantageous for certain human populations in Africa.
National Science Foundation, National Institutes of Health

Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania

Public Release: 11-Nov-2013
Clinical Immunology
Putting Lupus in permanent remission
Northwestern Medicine® scientists have successfully tested a nontoxic therapy that suppresses Lupus in blood samples of people with the autoimmune disease.
Alliance for Lupus Research, National Institutes of Health

Contact: Erin White
ewhite@northwestern.edu
847-491-4888
Northwestern University

Public Release: 11-Nov-2013
Journal of Allergy & Clinical Immunology
First genetic mutations linked to atopic dermatitis identified in African-American children
Two specific genetic variations in people of African descent are responsible for persistent atopic dermatitis, an itchy, inflammatory form of the skin disorder eczema. A new report by researchers in the Perelman School of Medicine at the University of Pennsylvania found that loss-of-function mutations to Filaggrin-2, a gene that creates a protein responsible for retaining moisture and protecting the skin from environmental irritants, were associated with atopic dermatitis in African American children.
NIH/National Institute of Arthritis Musculoskeletal and Skin Diseases

Contact: Kim Menard
kim.menard@uphs.upenn.edu
215-662-6183
University of Pennsylvania School of Medicine

Public Release: 11-Nov-2013
New England Journal of Medicine
APOL1 gene speeds kidney disease progression and failure in blacks, regardless of diabetes status
A large study co-authored by Penn Medicine researchers published this week in the New England Journal of Medicine found that African Americans with the APOL1 gene variant experience faster progression of chronic kidney disease and have a significantly increased risk of kidney failure, regardless of their diabetes status.
National Institutes of Health

Contact: Steve Graff
stephen.graff@uphs.upenn.edu
215-349-5653
University of Pennsylvania School of Medicine

Public Release: 11-Nov-2013
Nature Neuroscience
Signal found to enhance survival of new brain cells
A specialized type of brain cell that tamps down stem cell activity ironically, perhaps, encourages the survival of the stem cells' progeny, Johns Hopkins researchers report. Understanding how these new brain cells "decide" whether to live or die and how to behave is of special interest because changes in their activity are linked to neurodegenerative diseases such as Alzheimer's, mental illness and aging.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute of Environmental Health Sciences, NIH/National Institute of Child Health and Human Development, Dr. Miriam and Sheldon G. Adelson Medical Research Foundation, and others

Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine

Public Release: 11-Nov-2013
Journal of Clinical Investigation
New cause found for muscle-weakening disease myasthenia gravis
An antibody to a protein critical to enabling the brain to talk to muscles has been identified as a cause of myasthenia gravis, researchers report.
National Institutes of Health, Muscular Dystrophy Association

Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University

Public Release: 11-Nov-2013
CWRU team building an MRI-guided robotic heart catheter
Case Western Reserve University researchers are developing technologies to enable a doctor to see real-time images of a patient's beating heart and steer a robotic catheter through its chambers and ablate trouble spots using the push and pull of magnetic fields while the patient lies inside a magnetic resonance imager. The four-year project is funded with a $1.3 million grant from the National Institutes of Health.
National Institutes of Health

Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-368-4442
Case Western Reserve University

Public Release: 11-Nov-2013
Neuroscience 2013
Nature Neuroscience
What are you scared of?
What do bullies and sex have in common? Based on work by scientists at EMBL Monterotondo, it seems that the same part of the brain reacts to both. In a study published today in Nature Neuroscience, the researchers found that -- at least in mice -- different types of fear are processed by different groups of neurons. The findings could have implications for addressing phobias and panic attacks in humans.
National Institutes of Health, German Research Foundation, Chica and Heinz Schaller Research Foundation

Contact: Sonia Furtado Neves
sonia.furtado@embl.de
European Molecular Biology Laboratory

Public Release: 11-Nov-2013
Pediatrics
Brainstem abnormalities found in 'SIDS' infants, in both safe and unsafe sleep environments
Investigators at Boston Children's Hospital report that infants dying suddenly and unexpectedly, in both safe and unsafe sleep environments, have underlying brainstem abnormalities and are not all normal prior to death.
National Institutes of Health, NIH/National Institute of Child Health and Development

Contact: Andrea Duggan
andrea.duggan@childrens.harvard.edu
617-919-3110
Boston Children's Hospital

Public Release: 11-Nov-2013
Circulation: Journal of the American Heart Association
Device may help doctors diagnose lethal heart rhythm in womb
A device that records the natural magnetic activity of the heart helped researchers identify abnormal heart rhythms in unborn babies. It's the first sizable study to document the electrical aspects of long QT syndrome in the womb. The condition is a common cause of sudden death in early life and stillbirth.
National Institutes of Health

Contact: Bridgette McNeill
bridgette.mcneill@heart.org
214-706-1135
American Heart Association

Public Release: 10-Nov-2013
Nature Structural & Molecular Biology
Un-junking junk DNA
A study led by researchers at the University of California, San Diego School of Medicine shines a new light on molecular tools our cells use to govern regulated gene expression.
National Institutes of Health

Contact: Debra Kain
ddkain@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 10-Nov-2013
Philosophical Transactions of the Royal Society B
Fast-mutating DNA sequences shape early development; guided evolution of uniquely human traits
What does it mean to be human? According to scientists the key lies, ultimately, in the billions of lines of genetic code that comprise the human genome. The problem, however, has been deciphering that code. But now, researchers at the Gladstone Institutes have discovered how the activation of specific stretches of DNA control the development of uniquely human characteristics -- and tell an intriguing story about the evolution of our species.
NIH/National Institute of General Medical Sciences, NIH/National Heart, Lung and Blood Institute

Contact: Anne Holden
anne.holden@gladstone.ucsf.edu
415-734-2534
Gladstone Institutes

Public Release: 10-Nov-2013
Nature Medicine
Hope for transplant patients as study finds key to organ scarring
Patients with damaged organs could be helped by new treatments after scientists have discovered how tissues scar. Researchers say that the finding could pave the way for new drugs and eventually reduce the number of patients on organ transplant waiting lists.
Wellcome Trust, Medical Research Council, National Institutes of Health

Contact: Eleanor Cowie
eleanor.cowie@ed.ac.uk
44-131-650-6382
University of Edinburgh

Public Release: 10-Nov-2013
Nature Medicine
Research by Saint Louis University scientists offers way to disrupt fibrosis
Scientists have identified a pathway that regulates fibrosis, suggesting a possible pharmacologic approach to treat patients with a broad range of fibrotic diseases.
National Institutes of Health

Contact: Nancy Solomon
solomonn@slu.edu
314-977-8017
Saint Louis University

Public Release: 10-Nov-2013
Nature Biotechnology
Single-cell genome sequencing gets better
Researchers led by bioengineers at the University of California, San Diego have generated the most complete genome sequences from single E. coli cells and individual neurons from the human brain. Preliminary data suggest that individual neurons from the same brain have different genetic compositions. The breakthrough, published in Nature Biotechnology, comes from a new single-cell genome sequencing technique that confines genome amplification to fluid-filled wells with a volume of just 12 nanoliters.
National Institutes of Health, US National Science Foundation

Contact: Daniel Kane
dbkane@ucsd.edu
858-534-3262
University of California - San Diego

Public Release: 9-Nov-2013
Psychological Science
You want fries with that? Don't go there
A new Dartmouth neuroimaging study suggests chronic dieters overeat when the regions of their brain that balance impulsive behavior and self-control become disrupted, decreasing their capacity to resist temptation.
NIH/National Institute on Drug Abuse, NIH/National Heart, Lung, and Blood Institute

Contact: John Cramer
john.cramer@dartmouth.edu
603-646-9130
Dartmouth College

Public Release: 9-Nov-2013
ASN Kidney Week 2013
New England Journal of Medicine
Genetic variation increases risk of kidney disease progression in African-Americans
New research provides direct evidence that genetic variations in some African Americans with chronic kidney disease contribute to a more rapid decline in kidney function compared with white Americans. The research, led by investigators from the University of Maryland School of Medicine and Johns Hopkins University, may help explain, in part, why even after accounting for differences in socioeconomic background, end-stage kidney disease is twice as prevalent among blacks as whites.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Bill Seiler
bseiler@umm.edu
410-328-8919
University of Maryland Medical Center

Public Release: 9-Nov-2013
Neuroscience 2013
Simple dot test may help gauge the progression of dopamine loss in Parkinson's disease
Could figuring out how much dopamine a patient with Parkinson's disease has lost be as simple as completing a dot test? Researchers hope the easy task might lead to ways of improving clinical treatment of Parkinson's patients. "It is very difficult now to assess the extent of dopamine loss...," says lead author Katherine R. Gamble. "Use of this test may provide some help for physicians who treat people with Parkinson's disease..."
National Institutes of Health

Contact: Karen Mallet
km463@georgetown.edu
Georgetown University Medical Center

Showing releases 3401-3425 out of 3512.

<< < 132 | 133 | 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 > >>

     
   

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