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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3401-3425 out of 3543.

<< < 132 | 133 | 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 > >>

Public Release: 9-Dec-2013
Proceedings of the National Academy of Sciences
New sensor tracks zinc in cells
Shifts in zinc's location could be exploited for early diagnosis of prostate cancer.
NIH/National Institute of General Medical Sciences

Contact: Andrew Carleen
Massachusetts Institute of Technology

Public Release: 9-Dec-2013
Kids movies send mixed messages about eating habits and obesity
Many of the most popular children's movies from recent years feature both "obesogenic" behaviors and weight-related stigmatizing content, a study by University of North Carolina at Chapel Hill researchers finds.
N.C. Children's Promise, National Institutes of Health

Contact: Tom Hughes
University of North Carolina Health Care

Public Release: 9-Dec-2013
Grant supports creation of patient-derived stem cell lines for Alzheimer's research
Researchers at UC Irvine's Institute for Memory Impairments and Neurological Disorders have received a two-year, $600,000 grant from the National Institute on Aging to develop and study patient-derived stem cell lines.
NIH/National Institute on Aging

Contact: Tom Vasich
University of California - Irvine

Public Release: 9-Dec-2013
Biological Psychiatry
How a concussion can lead to depression years later
A head injury can lead immune-system brain cells to go on "high alert" and overreact to later immune challenges by becoming excessively inflammatory -- a condition linked with depressive complications, a new animal study suggests.
NIH/National Institute on Aging, Howard Hughes Medical Institute

Contact: Jonathan Godbout
Ohio State University

Public Release: 9-Dec-2013
Proceedings of the National Academy of Sciences
The smoking gun: Fish brains and nicotine
In researching neural pathways, it helps to establish an analogous relationship between a region of the human brain and the brains of more-easily studied animal species. New work from a team led by Carnegie's Marnie Halpern hones in on one particular region of the zebrafish brain that could help us understand the circuitry underlying nicotine addiction.
European Molecular Biology Organization, University of Virginia, National Institutes of Health

Contact: Marnie Halpern
Carnegie Institution

Public Release: 9-Dec-2013
Innovative drug-dispensing contact lens delivers glaucoma medication continuously for a month
Researchers at Massachusetts Eye and Ear/Harvard Medical School Department of Ophthalmology, Boston Children's Hospital, and the Massachusetts Institute of Technology are one step closer to an eye drop-free reality with the development of a drug-eluting contact lens designed for prolonged delivery of latanoprost, a common drug used for the treatment of glaucoma, the leading cause of irreversible blindness worldwide.
NIH/National Eye Institute, Massachusetts Eye Lions Research Fund, New England Cornea Transplant Fund, NIH/National Institute of General Medical Sciences

Contact: Mary Leach
Massachusetts Eye and Ear Infirmary

Public Release: 9-Dec-2013
JAMA Pediatrics
Communities across US reduce teen smoking, drinking, violence and crime
Fewer high school students across the US started drinking alcohol, smoking cigarettes, committing crimes and engaging in violence before graduation when their towns used the Communities That Care prevention system during the teens' middle school years. A University of Washington study found that the positive influence of this community-led system was sustained through high school.
National Institutes of Health

Contact: Molly McElroy
University of Washington

Public Release: 9-Dec-2013
Proceedings of the National Academy of Sciences
How 'sunshine vitamin' D may be helpful in fighting multiple sclerosis
In mice with a rodent form of multiple sclerosis, vitamin D appears to block damage-causing immune cells from migrating to the central nervous system, offering a potential explanation for why the so-called "sunshine vitamin" may prevent or ease symptoms of the neurodegenerative disease, according to results of a study at Johns Hopkins.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Stephanie Desmon
Johns Hopkins Medicine

Public Release: 9-Dec-2013
Journal of Clinical Investigation
Choloroquine reduces formation of bone resorbing cells in murine osteoporosis
In this issue of the Journal of Clinical Investigation, Brendan Boyce and colleagues at the University of Rochester evaluated the role of TNF receptor-associated receptor 3 in promoting osteoclast formation.
NIH/National Institute for Arthritis, Musculoskeletal and Skin Diseases

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 9-Dec-2013
Journal of Clinical Investigation
Breast cancer prognosis associated with oncometabolite accumulation
In this issue of the Journal of Clinical Investigation Stefan Ambs and colleagues at the National Cancer Institute discovered an association between the oncometabolite 2-hydroxyglutarate levels, DNA methylation patterns, and breast cancer prognosis.
National Institutes of Health, NIH/National Cancer Institute, CCR

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 8-Dec-2013
52nd Annual Meeting of the American College of Neuropsychopharmacology
Aging and gene expression -- possible links to autism and schizophrenia in offspring
Advanced paternal age has been associated with greater risk for psychiatric disorders, such as schizophrenia and autism. With an increase in paternal age, there is a greater frequency of certain types of mutations that contribute to these disorders in offspring. Recent research, however, looks beyond the genetic code to "epigenetic effects," which do not involve changes in the genes themselves, but rather in how they are expressed to determine one's characteristics.
NIH/National Institute of Mental Health, Simon Foundation, Brain and Behavior Research Foundation/NARSAD Young Investigator Award

Contact: Laura Hill
American College of Neuropsychopharmacology

Public Release: 8-Dec-2013
From common colds to deadly lung diseases, 1 protein plays key role
An international team of researchers has zeroed in on a protein that plays a key role in many lung-related ailments, from seasonal coughing and hacking to more serious diseases such as MRSA infections and cystic fibrosis. The finding advances knowledge about this range of illnesses and may point the way to eventually being able to prevent infections such as MRSA. The key protein is called MUC5B.
National Institutes of Health

Contact: Dan Meyers
University of Colorado Denver

Public Release: 8-Dec-2013
55th American Society of Hematology Annual Meeting
Flipping a gene switch reactivates fetal hemoglobin, may reverse sickle cell disease
Hematology researchers have manipulated key biological events in adult blood cells to produce a form of hemoglobin normally absent after the newborn period. Because fetal hemoglobin is unaffected by the genetic defect in sickle cell disease, these cell culture findings may open the door to a new therapy for the debilitating blood disorder.
National Institutes of Health, American Heart Association

Contact: Rachel Salis-Silverman
Children's Hospital of Philadelphia

Public Release: 8-Dec-2013
Nature Neuroscience
Extensive variability in olfactory receptors influences human odor perception
Researchers from the Monell Center and collaborating institutions have found that as much as 30 percent of the large array of human olfactory receptor differs between any two individuals. This substantial variation is in turn reflected by variability in how each person perceives odors.
NIH/National Institute on Deafness and Other Communication Disorders

Contact: Leslie Stein
Monell Chemical Senses Center

Public Release: 8-Dec-2013
Nature Methods
Novel method could help bring cancer biomarkers to clinic
International study demonstrates protein-measurement technique's potential to standardize quantification of the entire human proteome.
National Institutes of Health, NIH/National Cancer Institute

Contact: Deborah Bach
Fred Hutchinson Cancer Research Center

Public Release: 7-Dec-2013
55th American Society of Hematology Annual Meeting
Penn Medicine team reports on study of first 59 leukemia patients who received cell therapy
Three and a half years after beginning a clinical trial which demonstrated the first successful and sustained use of genetically engineered T cells to fight leukemia, a research team from the University of Pennsylvania will announce the latest data on 59 adults and children with advanced blood cancers that have failed to respond to standard therapies. Results in patients who received this investigational, personalized cellular therapy, known as CTL019, will be presented during the American Society of Hematology's Annual Meeting and Exposition.
NIH/National Cancer Institute, Leukemia and Lymphoma Society, Alliance for Cancer Gene Therapy, Novartis

Contact: Holly Auer
University of Pennsylvania School of Medicine

Public Release: 7-Dec-2013
55th American Society of Hematology Annual Meeting
International gene therapy trial for 'bubble boy' disease shows promising early results
Researchers reported promising outcomes data for the first group of boys with X-linked severe combined immunodeficiency syndrome, a fatal genetic immunodeficiency also known as "bubble boy" disease, who were treated in an international clinical study of a new form of gene therapy. The mechanism that delivered the gene therapy is designed to prevent the leukemia that arose a decade ago in a similar trial in Europe, when one-quarter of boys treated developed the blood cancer.
NIH/National Institute of Allergy & Infectious Diseases, NIH/National Heart Lung & Blood Institute

Contact: Irene Sege
Dana-Farber Cancer Institute

Public Release: 7-Dec-2013
Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities
Genetic mutations and molecular alterations may explain racial differences in head and neck cancers
A team of scientists at Johns Hopkins and in Texas has identified a handful of genetic mutations in black Americans, in addition to some chemical alterations affecting gene activity, which may help explain why the death rate among African-Americans from the most common form of head and neck cancer continues to hover some 18 percent higher above the death rate of whites with the same cancer.
NIH/National Cancer Institute, NIH/National Institute of Dental and Craniofacial Research

Contact: David March
Johns Hopkins Medicine

Public Release: 6-Dec-2013
Archives of Psychiatric Nursing
To improve foster care, add a psychiatric nurse to treatment team
Mental health nurses are a valuable addition to the team that treats teens who have psychiatric problems and are in the foster care system.
NIH/National Institute of Mental Health

Contact: Nancy Solomon
Saint Louis University

Public Release: 6-Dec-2013
Proceedings of the National Academy of Sciences
Clinical waste may prove valuable for monitoring treatment response in ovarian cancer
A microchip-based device developed by Massachusetts General Hospital investigators may greatly simplify the monitoring of patients' response to treatment for ovarian cancer -- the most lethal form of gynecologic cancer -- and certain other malignancies. The team reports using their device to isolate and identify tumor cells from ascites, an accumulation of fluid in the abdomen that often occurs in abdominal cancers.
National Institutes of Health, US Department of Defense

Contact: Cassandra Aviles
Massachusetts General Hospital

Public Release: 6-Dec-2013
Promising results for Swedish cancer drug candidate
A new study conducted by scientists from the Dana-Farber Cancer Institute at Harvard Medical School and Karolinska Institutet, Sweden presents very promising results for the treatment of the cancer form multiple myeloma. The drug candidate used in the research has been developed by scientists from Karolinska Institutet in and a Swedish company following its initial identification at the same university. The findings are so promising that the scientists are teaming up with Harvard to bring the drug to clinical trials on patients.
Swedish Research Council, Swedish Cancer Society, Swedish Foundation for Strategic Research, National Institutes of Health, and others

Contact: The Press Office
Karolinska Institutet

Public Release: 6-Dec-2013
Molecular Therapy
Penn study delivers protein across blood-brain barrier to degrade Alzheimer's plaques
University of Pennsylvania biologists substantially degraded Alzheimer's plaques in mice brains and human brain tissue by sending a fused protein across the blood-brain barrier. Their technique not only offers a potential strategy for treating the debilitating neurological disease, but also other diseases that affect the brain and eyes.
National Institutes of Health, Bill and Melinda Gates Foundation, Juvenile Diabetes Research Foundation, American Diabetes Association, American Heart Association, Research to Prevent Blindness

Contact: Katherine Unger Baillie
University of Pennsylvania

Public Release: 6-Dec-2013
Journal of National Cancer Institute
Gut microbes may be a risk factor for colorectal cancer
In one of the largest epidemiological studies of human gut bacteria and colorectal cancer ever conducted, a team of researchers at NYU Langone Medical Center has found a clear association between gut bacteria and colorectal cancer. The study, published today in the Journal of the National Cancer Institute, discovered that colorectal cancer patients had fewer beneficial bacteria and more harmful bacteria than people without the disease.
National Institutes of Health

Contact: Lorinda Klein
NYU Langone Medical Center / New York University School of Medicine

Public Release: 5-Dec-2013
Human Reproduction
Vaginally administered ED medication may alleviate menstrual cramping
Women with moderate to severe menstrual cramps may find relief in a class of erectile dysfunction drugs, according to a team of researchers led by Penn State College of Medicines Richard Legro.
National Institutes of Health

Contact: Matthew Solovey
Penn State

Public Release: 5-Dec-2013
Cancer Research
Prostate cancer biomarker may predict patient outcomes
Researchers at Vanderbilt University Medical Center and the University of Alberta in Canada have identified a biomarker for a cellular switch that accurately predicts which prostate cancer patients are likely to have their cancer recur or spread.
National Institutes of Health, Canadian Cancer Society Research Institute

Contact: Dagny Stuart
Vanderbilt University Medical Center

Showing releases 3401-3425 out of 3543.

<< < 132 | 133 | 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 > >>


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