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Key: Meeting M      Journal J      Funder F

Showing releases 3401-3425 out of 3645.

<< < 132 | 133 | 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 > >>

Public Release: 15-May-2014
Journal of Experimental Medicine
Penn Vet study reveals Salmonella's hideout strategy
A study led by researchers in the University of Pennsylvania's School of Veterinary Medicine reveals how some Salmonella bacteria hide from the immune system, allowing them to persist and cause systemic infection.
National Institutes of Health, University Research Foundation, McCabe Fund

Contact: Katherine Unger Baillie
University of Pennsylvania

Public Release: 15-May-2014
National Institutes of Health funding to help expand data storage capacity at UC Riverside
The University of California, Riverside, has received funding of $600,000 from the National Institutes of Health to support data-intensive research -- also often called Big Data science. The grant will make possible the purchase of a complex instrument: a Big Data cluster with high-performance CPU resources and data storage space equivalent to 5,000 modern laptops. Big Data has been identified as a contributor to the growth of the US economy over the next few decades.
National Institutes of Health

Contact: Iqbal Pittalwala
University of California - Riverside

Public Release: 15-May-2014
Substance Abuse
Anti-craving drug and counseling lower alcohol harm in homeless, without sobriety demands
Abstinence-based treatment has not been effective for many homeless people with alcohol dependence. They might benefit from an intervention that does not require them to stop or reduce drinking, according a preliminary Seattle study. Participants received monthly injections of an anti-craving medication, extended-release naltrexone. They met regularly with physicians to set their own treatment goals and to learn to be safer in their alcohol use. Early findings suggest this approach may reduce alcohol-related problems.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Leila Gray
University of Washington

Public Release: 15-May-2014
Nature Structural & Molecular Biology
Detailed studies reveal how key cancer-fighting protein is held in check
St. Jude Children's Research Hospital scientists have mapped the structural details of how p53 attaches to its regulatory protein, called BCL-xL, in the cell. The protein p53 is a key activator of the cell's protective machinery against genetic damage, such as the mutations that drive cancer cells' explosive growth.
National Institutes of Health, NIH/National Cancer Institute, American-Lebanese-Syrian Associated Charities

Contact: Summer Freeman
St. Jude Children's Research Hospital

Public Release: 15-May-2014
Psychological Science
Mothers' symptoms of depression predict how they respond to child behavior
Depressive symptoms seem to focus mothers' responses on minimizing their own distress, which may come at the expense of focusing on the impact their responses have on their children, according to research published in Psychological Science, a journal of the Association for Psychological Science.
NIH/National Institute of Child Health and Human Development

Contact: Anna Mikulak
Association for Psychological Science

Public Release: 15-May-2014
Proceedings of the Royal Society B
The color of blood: Pigment helps stage symbiosis in squid
The relationship between the Hawaiian bobtail squid and the bacterium Vibrio fischeri is well chronicled, but writing in the current issue of the journal Proceedings of the Royal Society B, a group led by University of Wisconsin-Madison microbiologists Margaret McFall-Ngai, Edward Ruby and their colleagues adds a new wrinkle to the story.
Marie Curie Actions, National Science Foundation, National Institutes of Health

Contact: Margaret McFall-Ngai
University of Wisconsin-Madison

Public Release: 15-May-2014
Biological Psychiatry
Effects of alcohol in young binge drinkers predicts future alcoholism
Heavy social drinkers who report greater stimulation and reward from alcohol are more likely to develop alcohol use disorder over time, report researchers from the University of Chicago, May 15 in the journal Biological Psychiatry. The findings run counter to existing hypotheses that innate tolerance to alcohol drives alcoholism.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Kevin Jiang
University of Chicago Medical Center

Public Release: 15-May-2014
'Bystander' chronic infections thwart development of immune cell memory
Studies of vaccine programs in the developing world have revealed that individuals with chronic infections such as malaria and hepatitis tend to be less likely to develop the fullest possible immunity benefits from vaccines for unrelated illnesses. Researchers have found that chronic bystander viral or parasitic infections impaired the development of memory T cells in mouse models of long-term infection and in immune cells of people chronic hepatitis C infection.
NIH/National Institutes of Allergy and Infectious Diseases

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 15-May-2014
Stem Cell Reports
Combination therapy a potential strategy for treating Niemann Pick disease
Whitehead Institute researchers have identified a potential dual-pronged approach to treating Niemann-Pick type C (NPC) disease, a rare but devastating genetic disorder. By studying nerve and liver cells grown from NPC patient-derived induced pluripotent stem cells (iPSCs), the scientists determined that although cholesterol does accumulate abnormally in the cells of NPC patients, a more significant problem may be defective autophagy -- a basic cellular function that degrades and recycles unneeded or faulty molecules, components, or organelles in a cell.
National Niemann-Pick Disease Foundation, University of Cambridge, National Institutes of Health, Skoltech Center

Contact: Nicole Giese Rura
Whitehead Institute for Biomedical Research

Public Release: 15-May-2014
Stroke: Journal of the American Heart Association
Older migraine sufferers may have more silent brain injury
Older migraine sufferers may be more likely to have silent brain injury. Ischemic silent brain infarctions are symptomless brain injuries and are a risk factor for future strokes. Researchers suggest people who have both migraines and vascular risk factors pay close attention to lifestyle factors that can reduce their chance of stroke.
NIH/National Institute of Neurological Diseases and Stroke

Contact: Karen Astle
American Heart Association

Public Release: 15-May-2014
New tool to grow cancer cells streamlines laboratory research
A new technique that allows the growth of both normal and cancer cells and keeps them alive indefinitely is transforming and expediting basic cancer research. 'We've had a glimpse of how these cells can provide an amazing advance in human cancer clinical research in preliminary work, and now we demonstrate how incredibly useful they are in laboratory cancer research,' says the lead researcher.
National Institutes of Health

Contact: Karen Teber
Georgetown University Medical Center

Public Release: 15-May-2014
PLOS Genetics
Complex interactions may matter most for longevity
A new study of the biology of aging shows that complex interactions among diet, mitochondrial DNA and nuclear DNA appear to influence lifespan at least as much as single factors alone. The findings may help scientists better understand the underlying mechanisms of aging and explain why studies of single factors sometimes produce contradictory results.
National Institutes of Health

Contact: David Orenstein
Brown University

Public Release: 14-May-2014
Journal of Visualized Experiments
SapC-DOPS technology may help with imaging brain tumors, research shows
The Cincinnati Cancer Center and University of Cincinnati Cancer Institute research studies published in an April online issue of the Journal of Magnetic Resonance Imaging and a May issue of the Journal of Visualized Experiments reveal possibly new ways to image glioblastoma multiforme tumors -- a form of brain tumor -- using the SapC-DOPS technology.
Mayfield Education and Research Foundation, New Drug State Key Project, NIH/National Cancer Institute

Contact: Katie Pence
University of Cincinnati Academic Health Center

Public Release: 14-May-2014
Journal of American College of Cardiology
Research shows hope for normal heart function in children with fatal heart disease
After two decades of arduous research, a National Institutes of Health-funded investigator at the Children's Hospital of Michigan at the Detroit Medical Center and the Wayne State University School of Medicine has published a new study showing that many children with an often fatal type of heart disease can recover 'normal size and function' of damaged sections of their hearts.
National Institutes of Health

Contact: Julie O'Connor
Wayne State University - Office of the Vice President for Research

Public Release: 14-May-2014
Researchers ID changes that may occur in neural circuits due to cocaine addiction
This is the first study to demonstrate the critical links between the levels of the trafficking protein, the potassium channels' effect on neuronal activity and a mouse's response to cocaine. Results from the study are published in the peer-reviewed journal Neuron earlier this month.
NIH/National Institute on Drug Abuse, Salk Institute, Chapman Foundation

Contact: Sid Dinsay
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 14-May-2014
Science Translational Medicine
Hitting a moving target
A vaccine or other therapy directed at a single site on a surface protein of HIV could in principle neutralize nearly all strains of the virus -- thanks to the diversity of targets the site presents to the human immune system.
International AIDS Vaccine Initiative, National Institutes of Health, Canadian Institutes of Health, Gates Foundation

Contact: Mika Ono
Scripps Research Institute

Public Release: 14-May-2014
Journal of Experimental Biology
Scientists investigate the role of the 'silent killer' inside deep-diving animals
Scientists at Scripps Institution of Oceanography at UC San Diego and Sonoma State University have furthered science's understanding of carbon monoxide's natural characteristics and limitations by studying the gas in one of the world's best divers: the elephant seal.
Office of Naval Research, National Institutes of Health, National Science Foundation

Contact: Mario Aguilera
University of California - San Diego

Public Release: 14-May-2014
Science Translational Medicine
Can anti-depressants help prevent Alzheimer's disease?
A University of Pennsylvania researcher has discovered that the common selective serotonin reuptake inhibitor citalopram arrested the growth of amyloid beta, a peptide in the brain that clusters in plaques that are thought to trigger the development of Alzheimer's disease. Penn, in collaboration with investigators at Washington University, tested the drug's effects on the brain interstitial fluid in plaque-bearing mice and the cerebrospinal fluid of healthy human subjects.
National Institutes of Health

Contact: Lee-Ann Donegan
University of Pennsylvania School of Medicine

Public Release: 14-May-2014
Possible new plan of attack for opening and closing the blood-brain barrier
Researchers have identified the first gene that controls blood-brain barrier permeability through a little-studied phenomenon calledtranscytosis. The study, which was conducted in mice, offers a new way to devise strategies to open the blood-brain barrier for drug delivery or restore it in neurological disease.
National Institutes of Health, Alfred P. Sloan Foundation, Harvard Medical School

Contact: David Cameron
Harvard Medical School

Public Release: 14-May-2014
Science Translational Medicine
Inhibiting protein family helps mice survive radiation exposure, Stanford study finds
Tinkering with a molecular pathway that governs how intestinal cells respond to stress can help mice survive a normally fatal dose of abdominal radiation, according to a new study by researchers at the Stanford University School of Medicine. Because the technique is still partially effective up to 24 hours after exposure, the study suggests a possible treatment for people unintentionally exposed to large amounts of radiation, such as first responders at the Chernobyl nuclear disaster in 1986.
National Institutes of Health, Radiological Society of North America

Contact: Krista Conger
Stanford University Medical Center

Public Release: 13-May-2014
Environmental Science: Processes and Impacts
Clean air in Iowa
A new study from the University of Iowa reports Iowa's air quality falls within government guidelines for cleanliness, based on data gathered at five locations statewide. The study analyzed air quality and pollution sources in the state and is the first to compare air quality in urban versus rural areas. Results appear in the journal Environmental Science: Processes and Impacts.
National Institutes of Health.

Contact: Richard Lewis
University of Iowa

Public Release: 13-May-2014
Journal of Neuroscience
Human learning altered by electrical stimulation of dopamine neurons
Stimulation of a certain population of neurons within the brain can alter the learning process, according to a team of neuroscientists and neurosurgeons at the University of Pennsylvania. A report in the Journal of Neuroscience describes for the first time that human learning can be modified by stimulation of dopamine-containing neurons in a deep brain structure known as the substantia nigra.
National Institutes of Health

Contact: Kim Menard
University of Pennsylvania School of Medicine

Public Release: 13-May-2014
Protein Data Bank: 100,000 structures
Four wwPDB data centers in the US, UK and Japan support online access to three-dimensional structures of biological macromolecules that help researchers understand many facets of biomedicine, agriculture, and ecology, from protein synthesis to health. This public archive of experimentally determined protein and nucleic acid structures has reached a critical milestone of 100,000 structures, thanks to the efforts of structural biologists throughout the world.
National Science Foundation, National Institutes of Health, US Department of Energy

Contact: Christine Zardecki
Rutgers University

Public Release: 13-May-2014
TB lung infection causes changes in the diversity of gut bacteria in mice
Johns Hopkins researchers have found evidence in mice that a tuberculosis infection in the lungs triggers immune system signaling to the gut that temporarily decreases the diversity of bacteria in that part of the digestive tract.
Howard Hughes Medical Institute, NIH/National Institute of Allergy and Infectious Diseases

Contact: Stephanie Desmon
Johns Hopkins Medicine

Public Release: 13-May-2014
Journal of Neuroscience
Role of calcium in familial Alzheimer's disease clarified, pointing to new therapeutics
Mutations in two presenilin proteins associated with familial Alzheimer's disease disrupt the flow of calcium ions within neurons. Researchers have found that suppressing the hyperactivity of the calcium channels alleviated FAD-like symptoms in mice models of the disease. These new observations suggest that approaches based on modulating calcium signaling could be explored for new AD therapies.
NIH/National Institute of Mental Health

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Showing releases 3401-3425 out of 3645.

<< < 132 | 133 | 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 > >>


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