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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3401-3425 out of 3685.

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Public Release: 29-Dec-2014
Stem Cells
Reprogramming stem cells may prevent cancer after radiation
University of Colorado Cancer Center study published today in Stem Cells shows that pre-programmed stem cell death allows cancer to grow after full-body irradiation, and that NOTCH signaling may restore stem cell function, protecting against cancer after radiation.
National Institutes of Health, Leukemia and Lymphoma Society

Contact: Garth Sundem
University of Colorado Anschutz Medical Campus

Public Release: 29-Dec-2014
Clinical Intervensions in Aging
Patient self-reporting version of 'blood pressure cuff' for dementia is reliable and valid
Patient self-reporting version of the Healthy Aging Brain Care Monitor -- a primary-care tool to measure cognitive, functional and psychological symptoms -- is user-friendly, reliable and valid, including being sensitive to symptom change, according to new Regenstrief Institute and Indiana University Center for Aging Research study.
NIH/National Institute of Mental Health, NIH/National Institute on Aging

Contact: Cindy Fox Aisen
Indiana University

Public Release: 29-Dec-2014
Protein ID'd as possible universal therapeutic target for many infections, including Ebola
A protein called GRP78 could be a universal therapeutic target for treating human diseases like brain cancer, Ebola, influenza, hepatitis and superbug bacteria such as methicillin-resistant Staphylococcus epidermidis and methicillin-resistant Staphylococcus aureus, according to a Virginia Commonwealth University-led preclinical study published this month in the Journal of Cellular Physiology.
National Institutes of Health, Virginia Commonwealth University

Contact: Brian McNeill
Virginia Commonwealth University

Public Release: 29-Dec-2014
Molecular and Cellular Biology
Enzyme's alter ego helps activate the immune system
Already known to cut proteins, the enzyme SPPL3 turns out to have additional talents, according to a new study from Johns Hopkins. In its newly discovered role, SPPL3 works without cutting proteins to activate T-cells, the immune system's foot soldiers. Because its structure is similar to that of presenilin enzymes, which have been implicated in Alzheimer's disease, the researchers believe their findings could shed more light on presenilin functions, in addition to providing new insight into how the immune system is controlled.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Catherine Kolf
Johns Hopkins Medicine

Public Release: 29-Dec-2014
Text messaging reminders increase second dose influenza vaccinations in children
Researchers studied the impact of text message reminders for the second dose of influenza vaccine required for many young children to protect them against the virus. The findings showed that sending the reminders increased receipt of the second dose of the vaccine and brought children in sooner to be vaccinated. When educational information on the importance of the second dose of influenza vaccine was embedded into the text messages there was an even greater effect.
NIH/National Cancer Institute

Contact: Stephanie Berger
Columbia University's Mailman School of Public Health

Public Release: 29-Dec-2014
Proceedings of the National Academy of Sciences
Sugar molecule links red meat consumption and elevated cancer risk in mice
While people who eat a lot of red meat are known to be at higher risk for certain cancers, other carnivores are not, prompting researchers at the University of California, San Diego School of Medicine to investigate the possible tumor-forming role of a sugar called Neu5Gc, which is naturally found in most mammals but not in humans.
Ellison Medical Foundation, NIH/National Cancer Institute, Samuel and Ruth Engelberg Fellowship from the Cancer Research Institute, Swiss National Science Foundation

Contact: Scott LaFee
University of California - San Diego

Public Release: 26-Dec-2014
UH Cancer Center researcher looks to ocean to treat sepsis
A graduate research assistant at the UH Cancer Center and Ph.D. candidate at the John A. Burns School of Medicine, screens small molecules from fungi and Hawaiian marine organisms for extracts that will fight sepsis.
National Institutes of Health, NIH/National Institute of General Medical Science

Contact: Tina Shelton
University of Hawaii Cancer Center

Public Release: 26-Dec-2014
Binge drinking disrupts immune system in young adults, study finds
Binge drinking in young, healthy adults significantly disrupts the immune system, according to a study in the journal Alcohol. Drinkers generally understand how binge drinking alters behavior. But there is less awareness of alcohol's harmful effects in other areas, such as the immune system.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Jim Ritter
Loyola University Health System

Public Release: 24-Dec-2014
Cell Reports
Locking mechanism found for 'scissors' that cut DNA
Researchers at Johns Hopkins have discovered what keeps an enzyme from becoming overzealous in its clipping of DNA. Since controlled clipping is required for the production of specialized immune system proteins, an understanding of what keeps the enzyme in check should help explain why its mutant forms can lead to immunodeficiency and cancer.
NIH/National Cancer Institute, Institute for Cell Engineering

Contact: Catherine Kolf
Johns Hopkins Medicine

Public Release: 23-Dec-2014
Molecular Metabolism
High-fat diet, obesity during pregnancy harms stem cells in developing fetus
Physician-scientists at OHSU Doernbecher Children's Hospital reveal a high-fat diet and obesity during pregnancy compromise the blood-forming, or hematopoietic, stem cell system in the fetal liver responsible for creating and sustaining lifelong blood and immune system function.
National Center for Advancing Translational Sciences of the National Institutes of Health, Friends of Doernbecher

Contact: Tamara Hargens-Bradley
Oregon Health & Science University

Public Release: 23-Dec-2014
126th Annual Meeting of the Southern Surgical Association
Journal of the American College of Surgeons
To remove the gallbladder or not -- that is the question
Gallbladder removal is one of the most common operations performed in older adults. Yet, research from the University of Texas Medical Branch at Galveston shows many patients who would benefit most from the surgery don't get it.
National Institutes of Health, Agency for Healthcare Research and Quality

Contact: Donna Ramirez
University of Texas Medical Branch at Galveston

Public Release: 23-Dec-2014
UTHealth research: Children's High Risk Clinic reduces serious illness by 55 percent
High-risk children with chronic illness who received comprehensive care at a special clinic staffed by physicians and nurse practitioners from The University of Texas Health Science Center at Houston, had a dramatic reduction in serious illnesses as documented in a study published in the Dec. 24/31 issue of JAMA. These benefits are the greatest identified to date for medical homes for patients in any age group.
Centers for Medicare & Medicaid Services, Texas Health and Human Services, NIH/National Center for Advancing Translational Sciences

Contact: Deborah Mann Lake
University of Texas Health Science Center at Houston

Public Release: 23-Dec-2014
Science Signaling
Researchers map paths to cancer drug resistance
A team of researchers led by Duke Cancer Institute has identified key events that prompt certain cancer cells to develop resistance to otherwise lethal therapies.
National Institutes of Health

Contact: Sarah Avery
Duke University Medical Center

Public Release: 23-Dec-2014
Grant supports use of data science to optimize HIV treatment monitoring
A Brown University biostatistician and an infectious disease specialist have received a $3.5-million grant to develop new ways to use data from patient health records to optimize effectiveness of HIV treatment where resources are limited, such as in the developing world. They will work with an HIV care program in Kenya that provides healthcare to more than 130,000 patients a year.
National Institutes of Health

Contact: David Orenstein
Brown University

Public Release: 23-Dec-2014
Proceedings of the National Academy of Sciences
Researchers shed light on how 'microbial dark matter' might cause disease
For decades the bacteria group Candidate Phylum TM7, thought to cause inflammatory mucosal diseases, has posed a particular challenge for researchers. A landmark discovery has revealed insights into TM7's resistance to scientific study and to its role in the progression of periodontitis and other diseases. Their findings shed new light on the biological, ecological and medical importance of TM7, and could lead to better understanding of other elusive bacteria.
NIH/National Institute of Dental and Craniofacial Research, NIH/National Institute of General Medical Sciences

Contact: Brianna Aldrich
University of California - Los Angeles

Public Release: 23-Dec-2014
Nature Communications
SLU researcher discovers a way to control internal clocks
Researchers hypothesize that targeting components of the mammalian clock with small molecules like REV-ERB drugs may lead to new treatments for sleep disorders and anxiety disorders. It also is possible that REV-ERB drugs may be leveraged to help in the treatment of addiction.
National Institutes of Health

Contact: Carrie Bebermeyer
Saint Louis University

Public Release: 23-Dec-2014
Journal of American Academy of Child and Adolescent Psychiatry
Could playing Tchaikovsky's 'Nutcracker' and other music improve kids' brains?
In a study called 'the largest investigation of the association between playing a musical instrument and brain development,' Medicine Vermont child psychiatry team has found that musical training might also help kids focus their attention, control their emotions and diminish their anxiety.
NIH/National Institute of Child Health and Human Development, NIH/National Institute on Drug Abuse, NIH/National Institute of Mental Health, NIH/National Institute of Neurological Disorders and Stroke.

Contact: Jennifer Nachbur
University of Vermont

Public Release: 23-Dec-2014
Study confirms Ebola and Marburg virus DNA vaccines are safe and immunogenic in Africa
Results from the first Ebola vaccine clinical trial conducted in Africa (in 2009-2010) reveal a vaccine candidate produces the same immune response seen in the United States in an African setting. The findings of this 2009-2010 study, published online today in The Lancet, describe the successful execution and analysis of a Phase 1 clinical trial of two DNA vaccine candidates, one for the Ebola virus and the other for the closely related Marburg virus.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Lisa Reilly
The U.S. Military HIV Research Program (MHRP)

Public Release: 23-Dec-2014
The heat is on: Causes of hospitalization due to heat waves identified
In the largest and most comprehensive study of heat-related illness to date, Harvard School of Public Health researchers have identified a handful of potentially serious disorders that put older Americans at significantly increased risk of winding up in the hospital during periods of extreme heat.
NIH/National Institute of Environmental Health Sciences, US Environmental Protection Agency, National Institutes of Health

Contact: Todd Datz
Harvard T.H. Chan School of Public Health

Public Release: 23-Dec-2014
Molecular mechanism behind health benefits of dietary restriction identified
A new study led by Harvard School of Public Health researchers identifies a key molecular mechanism behind the health benefits of dietary restriction.
National Institutes of Health, Glenn Foundation, Austrian Science Fund

Contact: Todd Datz
Harvard T.H. Chan School of Public Health

Public Release: 22-Dec-2014
Biophysical Journal
Penn researchers model the mechanics of cells' long-range communication
Interdisciplinary research at the University of Pennsylvania is showing how cells interact over long distances within fibrous tissue, like that associated with many diseases of the liver, lungs and other organs.
National Institutes of Health, National Science Foundation

Contact: Evan Lerner
University of Pennsylvania

Public Release: 22-Dec-2014
Proceedings of the National Academy of Sciences
Graying, but still golden
Getting old doesn't spell doom when it comes to making important financial decisions, a team of researchers led by a University of California, Riverside assistant professor report in a just published paper.
NIH/National Institute on Aging, National Endowment for Financial Education

Contact: Sean Nealon
University of California - Riverside

Public Release: 22-Dec-2014
Oregon study links physical violence, stress hormone in women
A new study links physical violence against women by male partners to a disruption of a key steroid hormone that opens the door potentially to a variety of negative health effects.
National Institutes of Health

Contact: Jim Barlow
University of Oregon

Public Release: 22-Dec-2014
Journal of Clinical Oncology
Risk for leukemia after treatment for early-stage breast cancer higher than reported
The risk of developing leukemia after radiation therapy or chemotherapy for early stage breast cancer remains very small, but it is twice as high as previously reported, according to results of a new study led by researchers at the Johns Hopkins Kimmel Cancer Center.
NIH/National Cancer Institute, Susan G. Komen for the Cure

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 22-Dec-2014
Nature Nanotechnology
New non-invasive method can detect Alzheimer's disease early
Northwestern University researchers have developed a noninvasive MRI approach that can detect the Alzheimer's disease in a living animal, well before typical Alzheimer's symptoms appear. The research team developed an MRI probe that pairs a magnetic nanostructure with an antibody that seeks out the amyloid beta brain toxins responsible for onset of the disease. The accumulated toxins, because of the associated magnetic nanostructures, show up as dark areas in MRI scans of the brain.
NIH/National Institute on Aging, Baxter Healthcare

Contact: Megan Fellman
Northwestern University

Showing releases 3401-3425 out of 3685.

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