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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3426-3450 out of 3684.

<< < 133 | 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 | 142 > >>

Public Release: 25-May-2014
Nature Cell Biology
Study identifies how signals trigger cancer cells to spread
Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a signaling pathway in cancer cells that controls their ability to invade nearby tissues in a finely orchestrated manner. The findings offer insights into the early molecular events involved in metastasis, the deadly spread of cancer cells from primary tumor to other parts of the body. The study was published today in the online edition of Nature Cell Biology.
National Institutes of Health

Contact: Kim Newman
Albert Einstein College of Medicine

Public Release: 25-May-2014
Nature Chemical Biology
Team validates potentially powerful new way to treat HER2-positive breast cancer
Scientists at Cold Spring Harbor Laboratory today reported a discovery that they hope will lead to the development of a powerful new way of treating an aggressive form of breast cancer called HER2-positive.
National Institutes of Health, American Diabetes Association, Brown University Seed Fund Cold Spring Harbor Laboratory Cancer Center

Contact: Peter Tarr
Cold Spring Harbor Laboratory

Public Release: 23-May-2014
G3: Genes|Genomes|Genetics
Untangling whole genomes of individual species from a microbial mix
A new approach to studying microbes in the wild will allow scientists to sequence the genomes of individual species from complex mixtures. It marks a big advance for understanding the enormous diversity of microbial communities -- including the human microbiome. The work is described in an article published May 22 in Early Online form in the journal G3: Genes|Genomes|Genetics, published by the Genetics Society of America.
NIH/National Human Genome Research Institute, National Science Foundation, US Department Of Energy

Contact: Raeka Aiyar
Genetics Society of America

Public Release: 22-May-2014
Cell Host & Microbe
Bacterial adaptation contributes to pneumococcal threat in sickle cell disease patients
Researchers have identified differences in the genetic code of pneumococcal bacteria that may explain why it poses such a risk to children with sickle cell disease and why current vaccines don't provide better protection against the infection. St. Jude Children's Research Hospital scientists led the study, which appeared earlier this month in the journal Cell Host & Microbe.
NIH/Heart, Lung and Blood Institute, NIH/National Institute of Allergy and Infectious Diseases, Charles H. Hood Foundation, ALSAC

Contact: Summer Freeman
St. Jude Children's Research Hospital

Public Release: 22-May-2014
Developmental Cell
Male and female sex cell determination requires lifelong maintenance and protection
The way in which the sex of an organism is determined may require lifelong maintenance, finds new research from the University of Minnesota. According to the study published today in the journal Developmental Cell, sex-specific transcription factors perform lifelong work to maintain sexual determination and protect against reprogramming of cells from one sex to the other.
National Institutes of Health, National Science Foundation, Minnesota Medical Foundation, French Agence Nationale de la Recherche

Contact: Caroline Marin
University of Minnesota Academic Health Center

Public Release: 22-May-2014
Cell Metabolism
Study shows how common obesity gene contributes to weight gain
Researchers have discovered how a gene commonly linked to obesity -- FTO -- contributes to weight gain. The study shows that variations in FTO indirectly affect the function of the primary cilium, a little-understood hair-like appendage on brain and other cells. The findings, made in mice, suggest that it might be possible to modify obesity through interventions that alter the function of the cilium, according to scientists at Columbia University Medical Center.
National Institutes of Health

Contact: Karin Eskenazi
Columbia University Medical Center

Public Release: 22-May-2014
Proceedings of the National Academy of Sciences
Signals found that recruit host animals' cells, enabling breast cancer metastasis
Working with mice, Johns Hopkins researchers report they have identified chemical signals that certain breast cancers use to recruit two types of normal cells needed for the cancers' spread. A description of the findings appears in the online early May edition of the Proceedings of the National Academy of Sciences.
American Cancer Society, NIH/National Cancer Institute

Contact: Shawna Williams
Johns Hopkins Medicine

Public Release: 22-May-2014
Temple scientists receive $11.5 million grant for heart failure research
Innovative treatments for heart failure are lacking, leaving the nearly six million Americans who suffer from the condition with little hope for a cure. But thanks to an $11.5-million Program Project Grant from the National Heart, Lung, and Blood Institute, scientists at Temple University School of Medicine are now set to further their investigation of key molecular mechanisms in heart failure, an effort that is expected to lead to the development of new heart therapies.
NIH/National Heart, Lung and Blood Institute

Contact: Jeremy Walter
Temple University Health System

Public Release: 22-May-2014
New details on microtubules and how the anti-cancer drug Taxol works
Berkeley Lab researchers have produced images of microtubule assembly and disassembly at the unprecedented resolution of 5 angstroms, providing new insight into the success of the anti-cancer drug Taxol and pointing the way to possible improvements.
National Institutes of Health

Contact: Lynn Yarris
DOE/Lawrence Berkeley National Laboratory

Public Release: 22-May-2014
American Journal of Lifestyle Medicine
'I can' mentality goes long way after childbirth
The way a woman feels about tackling everyday physical activities, including exercise, may be a predictor of how much weight she'll retain years after childbirth says a Michigan State University professor.
National Institutes of Health

Contact: Sarina Gleason
Michigan State University

Public Release: 22-May-2014
CA: A Cancer Journal for Clinicians
US obesity epidemic making all segments of the nation fatter, study finds
Many reasons have been blamed for the US obesity epidemic -- fast food, suburban sprawl, the size of prepared meals, poverty, affluence, a lack of exercise and a shortage of access to healthy foods. A new study outlines how the nation's historically cheap food supply may be contributing to the problem.
National Institutes of Health

Contact: Warren Robak
RAND Corporation

Public Release: 22-May-2014
Cancer Cell
Study: Some pancreatic cancer treatments may be going after the wrong targets
New research represents a significant change in the understanding of how pancreatic cancer grows -- and how it might be defeated.
National Institutes of Health, American Gastroenterological Association/Foundation for Digestive Health and Nutrition

Contact: Nicole Fawcett
University of Michigan Health System

Public Release: 22-May-2014
CA: A Cancer Journal for Clinicians
Review says inexpensive food a key factor in rising obesity
A new review identifies an important factor fueling the obesity epidemic: Americans now have the cheapest food available in history.
National Institutes of Health, RAND

Contact: David Sampson
American Cancer Society

Public Release: 22-May-2014
One molecule to block both pain and itch
Duke University researchers have found an antibody that simultaneously blocks the sensations of pain and itching in studies with mice. The new antibody works by targeting the voltage-sensitive sodium channels in the cell membrane of neurons. The results appear online on May 22 in Cell.
National Institutes of Health

Contact: Karl Bates
Duke University

Public Release: 22-May-2014
JAMA Otolaryngology - Head & Neck Surgery
IU researchers identify pattern of cognitive risks in some children with cochlear implants
Children with profound deafness who receive a cochlear implant had as much as five times the risk of having delays in areas of working memory, controlled attention, planning and conceptual learning as children with normal hearing, according to Indiana University research published May 22 in the Journal of the American Medical Association Otolaryngology--Head and Neck Surgery.
NIH/National Institute on Deafness and Other Communication Disorders

Contact: Mary Hardin
Indiana University

Public Release: 22-May-2014
Cancer Cell
Supportive tissue in tumors hinders, rather than helps, pancreatic cancer
Study finds that fibrosis is part of the body's effort to contain and thwart pancreatic cancer. When it's stopped, the disease progresses faster, which aligns with clinical trial results.
NIH/National Cancer Institute, Cancer Prevention and Research Institute of Texas

Contact: Scott Merville
University of Texas M. D. Anderson Cancer Center

Public Release: 22-May-2014
Discovery of how Taxol works could lead to better anticancer drugs
Taxol, one of the most widely used anticancer drugs, interferes with the splitting of cells, preferentially killing actively dividing cancer cells. A UC Berkeley team led by biophysicist Eva Nogales has discovered how Taxol works. The drug binds to microtubules, part of the cell's skeleton, and prevents compaction of the tubulin subunits, which normally spring-loads the molecule so that it rapidly peels apart when required. Taxol prevents that peeling, immobilizing microtubules and killing the cell.
NIH/National Institute of General Medical Sciences, Damon Runyon, Howard Hughes Medical Institute

Contact: Robert Sanders
University of California - Berkeley

Public Release: 22-May-2014
Personality and Social Psychology Bulletin
Aggressive behavior observed after alcohol-related priming
It has been well documented by previous research that the consumption of alcohol is directly linked to an increase in aggression and other behavioral extremes. But can simply seeing alcohol-related words have a similar effect on aggressive behavior?
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Jennifer Santisi
Society for Personality and Social Psychology

Public Release: 22-May-2014
Fruit flies show mark of intelligence in thinking before they act
Fruit flies 'think' before they act, a study by researchers from the University of Oxford's Centre for Neural Circuits and Behaviour suggests. The neuroscientists showed that fruit flies take longer to make more difficult decisions.
Wellcome Trust, Gatsby Charitable Foundation, National Institutes of Health, Oxford Martin School

Contact: Oxford University news & information office
University of Oxford

Public Release: 22-May-2014
RI Hospital researcher and colleagues discover protein that may lead to malaria vaccine
Rhode Island Hospital researchers have discovered a protein that is essential for malaria-causing parasites to escape from inside red blood cells. This protein could lead to the development of a vaccine that would prevent the progression of Plasmodium falciparum malaria, which kills one child every 15 seconds each year in Sub-Saharan Africa and Southeast Asia, according to new research by Jonathan Kurtis, M.D., Ph.D., and colleagues.
National Institutes of Health, Bill and Melinda Gates Foundation

Contact: Ellen Slingsby

Public Release: 21-May-2014
Molecule acts as umpire to make tough life-or-death calls
Researchers have demonstrated that an enzyme required for animal survival after birth functions like an umpire, making the tough calls required for a balanced response to signals that determine if cells live or die. St. Jude Children's Research Hospital scientists led the study, which was published online and appears in the May 22 edition of the scientific journal Cell.
National Institutes of Health, ALSAC

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 21-May-2014
New England Journal of Medicine
Univ. of MD researchers identify fat-storage gene mutation that may increase diabetes risk
Researchers at the University of Maryland School of Medicine have identified a mutation in a fat-storage gene that appears to increase the risk for type 2 diabetes and other metabolic disorders, according to a study published online today in the New England Journal of Medicine.
National Institutes of Health, and others

Contact: Karen Warmkessel
University of Maryland Medical Center

Public Release: 21-May-2014
Cell Reports
TSRI scientists catch misguided DNA-repair proteins in the act
Scientists led by a group of researchers at The Scripps Research Institute in La Jolla, CA, have discovered some of the key proteins involved in one type of DNA repair gone awry.
Pew Scholars, National Institutes of Health, Novartis Advanced Discovery Institute, Italian Ministry of Health, FIRC

Contact: Madeline McCurry Schmidt
Scripps Research Institute

Public Release: 21-May-2014
Drug-target database lets researchers match old drugs to new uses
A study recently published in the journal Bioinformatics describes a new database and pattern-matching algorithm that allows researchers to evaluate rational drugs and drug combinations, and also recommends a new drug combination to treat drug-resistant non-small cell lung cancer.
National Institutes of Health

Contact: Garth Sundem
University of Colorado Denver

Public Release: 21-May-2014
Disruption of circadian rhythms may contribute to inflammatory disease
A disruption of circadian rhythms, when combined with a high-fat, high-sugar diet, may contribute to inflammatory bowel disease and other harmful conditions, according to a recent study conducted by researchers at Rush University Medical Center. The study is online at the peer-reviewed, open-access journal, PLOS ONE.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Nancy DiFiore
Rush University Medical Center

Showing releases 3426-3450 out of 3684.

<< < 133 | 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 | 142 > >>


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