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Department of Health and Human Services

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Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 3426-3450 out of 3569.

<< < 133 | 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 | 142 > >>

Public Release: 13-Jan-2014
Proceedings of the National Academy of Sciences
Chemical signaling simulates exercise in cartilage cells
Cartilage is notoriously difficult to repair or grow, but researchers at Duke Medicine have taken a step toward understanding how to regenerate the connective tissue. By adding a chemical to cartilage cells, the chemical signals spurred new cartilage growth, mimicking the effects of physical activity.
National Institutes of Health

Contact: Rachel Harrison
rachel.harrison@duke.edu
919-419-5069
Duke University Medical Center

Public Release: 12-Jan-2014
Nature
UNC researchers find new route for better brain disorder treatments
Solving a 40-year-old mystery, scientists at the UNC School of Medicine and the Scripps Research Institute have discovered how salt acts as a key regulator for drugs used to treat a variety of brain diseases including chronic pain, Parkinson's disease, and depression.
NIH/National Institute of Drug Abuse, NIH/National Cancer Institute, and others

Contact: Mark Derewicz
mark.derewicz@unch.unc.edu
919-923-0959
University of North Carolina Health Care

Public Release: 12-Jan-2014
Nature Medicine
Tweaking MRI to track creatine may spot heart problems earlier, Penn Medicine study suggests
A new MRI method to map creatine at higher resolutions in the heart may help clinicians and scientists find abnormalities and disorders earlier than traditional diagnostic methods, researchers at the Perelman School of Medicine at the University of Pennsylvania suggest in a new study published online today in Nature Medicine.
National Institutes of Health

Contact: Steve Graff
stephen.graff@uphs.upenn.edu
215-349-5653
University of Pennsylvania School of Medicine

Public Release: 12-Jan-2014
Nature Methods
Designer 'swiss-army-knife' molecule captures RNA in single cells in their natural tissue environment
A multi-disciplinary team from the University of Pennsylvania have published in Nature Methods a first-of-its-kind way to isolate RNA from live cells in their natural tissue microenvironment without damaging nearby cells. This allows the researchers to analyze how cell-to-cell chemical connections influence individual cell function and overall protein production.
National Institutes of Health, McKnight Foundation

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 12-Jan-2014
Nature Neuroscience
It's all coming back to me now: Researchers find caffeine enhances memory
Caffeine is the energy boost of choice for millions. Now, however, researchers have found another use for the stimulant: memory enhancer.
NIH/National Institute on Aging, National Science Foundation, Johns Hopkins University

Contact: Latarsha Gatlin
lgatlin1@jhu.edu
443-997-9909
Johns Hopkins University

Public Release: 12-Jan-2014
Nature
Scientists solve 40-year mystery of how sodium controls opioid brain signaling
Scientists have discovered how the element sodium influences the signaling of a major class of brain cell receptors, known as opioid receptors. The discovery, from the Scripps Research Institute and the University of North Carolina, suggests new therapeutic approaches to a host of brain-related medical conditions.
National Institutes of Health, NIH/National Cancer Institute, NIH/National Institute for General Medical Sciences, NIH/National Institute of Mental Health

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 12-Jan-2014
Nature Medicine
Study identifies population of stem-like cells where HIV persists in spite of treatment
Now investigators from Massachusetts General Hospital and the Ragon Institute of MGH, MIT and Harvard may have found where HIV persists in the bodyin spite of antiviral treatment -- in a small group of recently identified T cells with stem-cell-like properties.
American Foundation for AIDS Research, National Institutes of Health

Contact: Sarah Dionne Sullivan
ssullivan38@partners.org
617-726-6126
Massachusetts General Hospital

Public Release: 11-Jan-2014
Journal of Behavioral and Developmental Pediatrics
Complementary medicine in wide use to treat children with autism, developmental delay
In a study of the range of treatments being employed for young children with autism and other developmental delays, UC Davis MIND Institute researchers have found that families often use complementary and alternative medicine treatments and that the most frequent users of both conventional and complementary approaches are those with higher levels of parental education and income.
NIH/National Institute of Environmental Health Sciences, US Environmental Protection Agency

Contact: Phyllis Brown
phyllis.brown@ucdmc.ucdavis.edu
916-734-9023
University of California - Davis Health System

Public Release: 10-Jan-2014
Nature Cell Biology
Study: Autophagy predicts which cancer cells live and die when faced with anti-cancer drugs
When a tumor is treated with an anti-cancer drug, some cells die and, unfortunately, some cells tend to live. A University of Colorado Cancer Center study published in the journal Nature Cell Biology details a possible difference between the susceptible and resistant cells: the rate at which cells are able to cleanse themselves via the process known as autophagy.
National Institutes of Health

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver

Public Release: 9-Jan-2014
Journal of the National Cancer Institute
Researchers develop tool to determine individual risk of prostate cancer overdiagnosis
Studies have found that prostate cancer is overdiagnosed in up to 42 percent of cases, prompting men to receive unnecessary treatment that can cause devastating side effects, including impotence and incontinence. Now, researchers at Fred Hutchinson Cancer Research Center and the University of Washington have developed a personalized tool that can predict the likelihood of prostate cancer overdiagnosis.
NIH/National Cancer Institute, Centers for Disease Control and Prevention

Contact: Deborah Bach
media@fredhutch.org
206-667-2210
Fred Hutchinson Cancer Research Center

Public Release: 9-Jan-2014
JAMA Psychiatry
Novel biomarker approach suggests new avenues to improve schizophrenia disease management
Environmental effects of events such as oxygen deprivation and infections may be preserved as markers in blood that are associated to schizophrenia, according to an international study led by the Virginia Commonwealth University School of Pharmacy's Center for Biomarker Research and Personalized Medicine.
NIH/National Institute of Mental Health

Contact: Eric Peters
petersem@vcu.edu
804-828-0563
Virginia Commonwealth University

Public Release: 9-Jan-2014
Journal of Clinical Investigation
Antipsychotic drug exhibits cancer-fighting properties
In a prime example of finding new uses for older drugs, studies in zebrafish show that a 50-year-old antipsychotic medication called perphenazine can actively combat the cells of a difficult-to-treat form of acute lymphoblastic leukemia, according to a study published in the Journal of Clinical Investigation. The drug works by turning on a cancer-suppressing enzyme called PP2A and causing malignant tumor cells to self-destruct.
NIH/National Cancer Institute, Leukemia & Lymphoma Society, and others

Contact: Irene Sege
irene.sege@childrens.harvard.edu
617-919-3110
Dana-Farber Cancer Institute

Public Release: 9-Jan-2014
Proceedings of the National Academy of Sciences
Some motor proteins cooperate better than others
A study at Rice University analyzes how teams of molecular motor proteins cooperate as they move cargoes around living cells.
Welch Foundation, National Institutes of Health

Contact: Jeff Falk
jfalk@rice.edu
713-348-6775
Rice University

Public Release: 9-Jan-2014
Journal of Biological Chemistry
LSUHSC research reveals structure of master regulator and new drug target for autism, cervical cancer
A team of scientists at LSU Health Sciences Center New Orleans has discovered the structure of the active form of E6-associated protein (E6AP), an enzyme that acts as a master regulator, controlling functions like the ability of nerve cells to "rewire" themselves in response to external stimuli and HPV hijacking cells leading to cervical cancer. They report, for the first time, that the active form of E6AP is composed of three distinct protein molecules.
National Institutes of Health

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center

Public Release: 9-Jan-2014
Blood
Red blood cells take on many-sided shape during clotting
Red blood cells are the body's true shape shifters, perhaps the most malleable of all cell types. While studying how blood clots contract researchers discovered a new geometry that red blood cells assume, when compressed during clot formation.
NIH/National Heart, Lung, and Blood Institute

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 9-Jan-2014
Neuron
SHY hypothesis explains that sleep is the price we pay for learning
Why do animals ranging from fruit flies to humans all need to sleep? After all, sleep disconnects them from their environment, puts them at risk and keeps them from seeking food or mates for large parts of the day.
NIH/National Institute of Mental Health

Contact: Susan Lampert Smith
ssmith5@uwhealth.org
608-890-5643
University of Wisconsin-Madison

Public Release: 9-Jan-2014
Journal of Endocrinology and Metabolism
Minorities and poor have more advanced thyroid cancers when diagnosed, UCLA study shows
UCLA researchers have found that minority patients and those of lower socioeconomic status are far more likely to have advanced thyroid cancer when they are diagnosed with the disease than white patients and those in higher economic brackets. In one of the most comprehensive studies of its kind, the UCLA team looked at nearly 26,000 patients with well-differentiated thyroid cancer and analyzed the impact of race and socioeconomic factors on the stage of presentation, as well as patient survival rates.
National Institutes of Health, Clinical Translational and Science Institute

Contact: Rachel Champeau
rchampeau@mednet.ucla.edu
310-794-2270
University of California - Los Angeles Health Sciences

Public Release: 9-Jan-2014
Science
Spinal cord findings could help explain origins of limb control
Northwestern University researchers have found that the spinal cord circuits that produce body bending in swimming fish are more complicated than previously thought. In a study of zebrafish, they report that differential control of an animal's musculature -- the basic template for controlling more complex limbs, such as in humans -- is already in place in the spinal networks of simple fish. The data could help clarify how vertebrates made the transition from water to land.
National Institutes of Health, Alfred P. Sloan Foundation, Esther A. and Joseph Klingenstein Fund

Contact: Megan Fellman
fellman@northwestern.edu
847-491-3115
Northwestern University

Public Release: 9-Jan-2014
Neuro-Oncology
Scientists uncover new target for brain cancer treatment
A new study is giving researchers hope that novel targeted therapies can be developed for glioblastoma multiforme, the most common and most aggressive form of brain cancer, after demonstrating for the first time that a gene known as melanoma differentiation associated gene-9/syntenin (mda-9/syntenin) is a driving force behind the disease's aggressive and invasive nature.
National Institutes of Health, NIH/National Cancer Institute

Contact: John Wallace
wallacej@vcu.edu
804-628-1550
Virginia Commonwealth University

Public Release: 9-Jan-2014
Physical Biology
Researchers develop test to predict early onset of heart attacks
A new "fluid biopsy" technique that could identify patients at high risk of a heart attack by identifying specific cells as markers in the bloodstream has been developed by a group of researchers at the Scripps Research Institute.
NIH/National Center for Research Resources, NIH/National Cancer Institute

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 9-Jan-2014
Cell Reports
A new pathway for neuron repair is discovered
A brand-new pathway for neuron repair has been discovered that could have implications for faster and improved healing after nerve damage. The research demonstrates, for the first time, that dendrites, the component of nerve cells that receive information from the brain, have the capacity to regrow after an injury.
National Institutes of Health, Pew Charitable Trusts

Contact: Barbara K.Kennedy
science@psu.edu
814-863-4682
Penn State

Public Release: 9-Jan-2014
Developmental Cell
Mystery solved: How nerve impulse generators get where they need to go
Scientists have solved a longstanding mystery of the central nervous system, showing how a key protein gets to the right spot to launch electrical impulses that enable communication of nerve signals to and from the brain.
National Institutes of Health, NIH/National Institute of Neurological Disorders and Stroke

Contact: Chen Gu
Gu.49@osu.edu
614-292-0349
Ohio State University

Public Release: 9-Jan-2014
PLOS Pathogens
UNC research demonstrates 'guided missile' strategy to kill hidden HIV
Researchers at the UNC School of Medicine have deployed a potential new weapon against HIV -- a combination therapy that targets HIV-infected cells that standard therapies cannot kill.
National Institutes of Health

Contact: Lisa Chensvold
lisa_chensvold@med.unc.edu
919-843-5719
University of North Carolina Health Care

Public Release: 9-Jan-2014
American Journal of Transplantation
Mass. General research could expand availability of hand, face transplants
Massachusetts General Hospital investigators have made an important step towards greater availability of hand transplants, face transplants and other transplants involving multiple types of tissue. In their report in the American Journal of Transplantation, the team describes how a procedure developed at the MGH to induce immune tolerance to organ transplants also induces tolerance to a model limb transplant in miniature swine.
National Institutes of Health, Musculoskeletal Transplant Foundation, Melina Nakos Foundation

Contact: Kristen Chadwick
kschadwick@partners.org
617-643-3907
Massachusetts General Hospital

Public Release: 9-Jan-2014
Journal of Clinical Investigation
Mice exposed to retinoid deficiency in utero exhibit bronchial hyperresponsiveness as adults
In this issue of the Journal of Clinical Investigation, Wellington Cardoso and colleagues at the Boston University School of Medicine reveal that mice born to mothers with retinoid deficiency during pregnancy are at increased risk of developing airway hyperesponsiveness.
National Institutes of Health

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation

Showing releases 3426-3450 out of 3569.

<< < 133 | 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 | 142 > >>

     
   

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