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News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3426-3450 out of 3477.

<< < 133 | 134 | 135 | 136 | 137 | 138 | 139 | 140 > >>

Public Release: 4-Oct-2013
Journal of Clinical Investigation
IU researchers, collaborators discover new therapeutic agents that may benefit leukemia patients
An Indiana University cancer researcher and his colleagues have discovered new therapeutic targets and drugs that may someday benefit people with certain types of leukemia or blood cancer.
National Institutes of Health

Contact: Michael Schug
Indiana University

Public Release: 4-Oct-2013
Stem cells engineered to become targeted drug factories
A group of Brigham and Women's Hospital, and Harvard Stem Cell Institute researchers and collaborators at MIT and MGH have found a way to use stem cells as drug delivery vehicles. The researchers inserted modified strands of messenger RNA into connective tissue stem cells -- called mesenchymal stem cells -- which stimulated the cells to produce adhesive surface proteins and secrete interleukin-10, an anti-inflammatory molecule.
National Institutes of Health

Contact: B. D. Colen
Harvard University

Public Release: 4-Oct-2013
ACS Chemical Biology
Rutgers scientists discover molecules that show promise for new anti-flu medicines
A new way to attack flu viruses is taking shape in laboratories at Rutgers University, where scientists have identified chemical agents that block the virus's ability to replicate itself in cell culture. These novel compounds show promise for a new class of antiviral medicines to fight much-feared pandemic influenza such as the looming "bird flu" threats caused by the H5N1 influenza A virus and the new H7N9 virus.
National Institutes of Health

Contact: Carl Blesch
732-932-7084 x616
Rutgers University

Public Release: 4-Oct-2013
High Medicare spending on prostate cancer screenings, but little benefit for older men
Prostate cancer screening has little benefit for men aged 75 and older, yet over three years, the Medicare fee-for-service program spent $447 million annually on PSA-based screenings -- one-third of which was for men in the over 75 age group, according to study by researchers at the Yale Cancer Outcomes, Public Policy, and Effectiveness Research Center.
National Institutes of Health

Contact: Karen N. Peart
Yale University

Public Release: 4-Oct-2013
Cancer Epidemiology, Biomarkers & Prevention
Cancer survivors in rural areas forgo health care because of cost
Older cancer survivors living in rural areas were more likely to forgo medical and dental care because of financial concerns compared with older cancer survivors living in urban areas, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
NIH/National Cancer Institute

Contact: Jeremy Moore
American Association for Cancer Research

Public Release: 3-Oct-2013
How an aggressive fungal pathogen causes mold in fruits and vegetables
A research team led by a University of California, Riverside molecular plant pathologist has discovered the mechanism by which an aggressive fungal pathogen infects almost all fruits and vegetables. The team discovered a novel virulence mechanism of Botrytis cinerea, a pathogen that can infect more than 200 plant species, causing serious gray mold disease on almost all fruits and vegetables that have been around, even at times in the refrigerator, for more than a week.
National Institutes of Health, National Science Foundation

Contact: Iqbal Pittalwala
University of California - Riverside

Public Release: 3-Oct-2013
Cell Stem Cell
Researchers unveil method for creating 're-specified' stem cells for disease modeling
A team led by researchers in the Boston Children's Hospital's Stem Cell Transplantation Program reports a new approach for turning induced pluripotent stem cells into hematopoietic stem and progenitor cells for in vivo disease modeling.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, NIH/National Heart, Lung and Blood Institute

Contact: Meghan Weber
Boston Children's Hospital

Public Release: 3-Oct-2013
New study suggests changing bacterial mix may lead to painful sex after menopause
The mix of bacteria in the vagina changes as women go through menopause. And a certain mix is typical after menopause in women who have vulvovaginal atrophy, a common cause of vaginal dryness and sexual pain, finds a team at Johns Hopkins and the University of Maryland. They suspect these bacteria may play a role in causing VVA.
National Institutes of Health

Contact: Eileen Petridis
The North American Menopause Society (NAMS)

Public Release: 3-Oct-2013
Kessler Foundation's Krch awarded $600,000 NIDRR grant for virtual reality study in TBI
Denise Krch, PhD, research scientist at Kessler Foundation was awarded a 3-year, $600,000 NIDRR Field-Initiated Grant titled "The development of a virtual reality program to improve executive functioning in individuals with traumatic brain injury (TBI)." Scientists will develop a virtual reality-based intervention that targets problem solving, mental flexibility, and divided attention, and to pilot test the completed prototype in a small sample of individuals with TBI who have moderate to severe impairment in executive function.
NIH/National Institute on Disability & Rehabilitation Research

Contact: Carolann Murphy
Kessler Foundation

Public Release: 3-Oct-2013
PLOS Neglected Tropical Diseases
Innovative approach could ultimately end deadly disease of sleeping sickness
A tag team of two bacteria, one of them genetically modified, has a good chance to reduce or even eliminate the deadly disease African trypanosomiasis, or sleeping sickness, researchers at Oregon State University conclude in a recent mathematical modeling study.
National Institutes of Health

Contact: Jan Medlock
Oregon State University

Public Release: 3-Oct-2013
Public Library of Science
Stem cells help repair traumatic brain injury by building a 'biobridge'
University of South Florida researchers suggest a new view of how stem cells may help repair the brain following trauma.
SanBio Inc, James and Esther King Biomedical Research Foundation, National Institutes of Health, Celgene Cellular Therapeutics

Contact: Anne DeLotto Baier
University of South Florida (USF Health)

Public Release: 3-Oct-2013
DNA nanotechnology opens new path to super-high-resolution molecular imaging
A team at the Wyss Institute for Biologically Inspired Engineering at Harvard University has been awarded a special $3.5 million grant from the National Institutes of Health to develop an inexpensive and easy-to-use new microscopy method that uses blinking DNA probes to spot many tiny components of cells simultaneously. The method could potentially lead to new ways of diagnosing disease and new insights into how the cell's components carry out their work.
National Institutes of Health

Contact: Dan Ferber
Wyss Institute for Biologically Inspired Engineering at Harvard

Public Release: 3-Oct-2013
CHOP genetics expert co-leads NIH grant on psychiatric illness in patients with deletion syndrome
Genetics experts from The Children's Hospital of Philadelphia are among the top leaders of a major international collaboration researching why patients with chromosome 22q11.2 deletion syndrome have an elevated risk of schizophrenia and other psychiatric illnesses. Discovering genes implicated in the deletion syndrome, a multisystem disorder, may offer important clues to the biological causes of mental illness in the general population.
NIH/National Institute of Mental Health

Contact: John Ascenzi
Children's Hospital of Philadelphia

Public Release: 3-Oct-2013
Penn co-leads $12 M NIH grant to study genetics of mental illnesses in deletion syndrome patients
A major international consortium co-led by Penn Medicine has received a $12 million National Institute of Mental Health grant for a large-scale genetics study investigating why patients with chromosome 22q11.2 deletion syndrome have an increased risk of schizophrenia and other psychiatric disorders.
NIH/National Institute of Mental Health

Contact: Steve Graff
University of Pennsylvania School of Medicine

Public Release: 3-Oct-2013
LSUHSC researcher discovers target for new Rx class for inflammatory disorders
Research led by Charles Nichols, Ph.D., Associate Professor of Pharmacology at LSU Health Sciences Center New Orleans, describes a powerful new anti-inflammatory mechanism that could lead to the development of new oral medications for atherosclerosis and inflammatory bowel disorders. The findings are published in PLOS ONE, available online at
NIH/National Heart, Lung, Blood Institute

Contact: Leslie Capo
Louisiana State University Health Sciences Center

Public Release: 3-Oct-2013
Blocking nerve cells could prevent symptoms of eczema
UC Berkeley research is leading to a new picture of how the nervous system interacts with the immune system to cause the itch and inflammation of eczema, a chronic skin disease. The new findings by neuroscientists Diana Bautista and Sarah Wilson could lead to new therapies for the condition, which afflicts 10 percent of the population at some point in their lives. In children, dry and itchy skin can progress to rashes, nasal allergies and asthma.
National Institutes of Health

Contact: Robert Sanders
University of California - Berkeley

Public Release: 3-Oct-2013
Journal of Biological Chemistry
Scripps Florida scientists identify potential new drug for inherited cancer
Scientists from the Florida campus of The Scripps Research Institute have identified a new drug candidate for an inherited form of cancer with no known cure.
National Institutes of Health, American Cancer Society, Afraxis, Inc.

Contact: Eric Sauter
Scripps Research Institute

Public Release: 3-Oct-2013
Cancer Cell
Triple-negative breast cancer target for drug development identified
Often deadly "triple-negative" breast cancers might be effectively treated in many cases with a drug that targets a previously unknown vulnerability in the tumors, according to a UC San Francisco researcher who described her discovery in a study published online October 3, 2013 in the journal Cancer Cell.
National Institutes of Health, Bay Area Breast Cancer Specialized Program Of Research Excellence, Durra Family Fund, Mount Zion Health Fund, Prospect Creek Foundation

Contact: Jeffrey Norris
University of California - San Francisco

Public Release: 3-Oct-2013
Science Express
Possible culprits in congenital heart defects identified
Mitochondria are the power plants of cells, manufacturing fuel so a cell can perform its many tasks. Mitochondria also are well known for their role in cell suicide. Now, researchers at Washington University School of Medicine in St. Louis and the University of Padua-Dulbecco Telethon Institute in Italy have shown that mitochondria also orchestrate events that determine a cell's future. The study identifies new potential genetic culprits in the origins of some congenital heart defects.
National Institutes of Health, Italian Telethon, ISHR-ES/SERVIER, Oncosuisse, AIRC, ERC

Contact: Julia Evangelou Strait
Washington University School of Medicine

Public Release: 3-Oct-2013
Silencing sudden death
Hypertrophic cardiomyopathy -- a disease in which cardiac muscle thickens, weakening the heart -- can be prevented from developing for several months in mice by reducing production of a mutant protein.
NIH/National Heart, Lung, and Blood Institute

Contact: David J Cameron
Harvard Medical School

Public Release: 3-Oct-2013
Molecular Cell
How a 'mistake' in a single-cell organism is actually a rewrite essential to life
A tiny but unexpected change to a segment of RNA in a single-cell organism looks a lot like a mistake, but is instead a change to the genetic information that is essential to the organism's survival.
National Institutes of Health

Contact: Juan Alfonzo
Ohio State University

Public Release: 3-Oct-2013
IDWeek 2013
JAMA Internal Medicine
High rates of unnecessary prescribing of antibiotics observed across the US
For decades, there has been a significant effort led by the Centers for Disease Control and Prevention and others to reduce inappropriate antibiotic prescribing. Despite this work, new research from Brigham and Women's Hospital finds only incremental improvement in antibiotic prescribing for adults with acute bronchitis and sore throat. These findings were presented at IDWeek on October 3, 2013 and the sore throat data was published online in JAMA Internal Medicine.
National Institutes of Health, NIH/National Institute of Allergy and Infectious Disease, Agency for Healthcare Research and Quality

Contact: Lori J Schroth
Brigham and Women's Hospital

Public Release: 3-Oct-2013
Power of precision medicine shown in successful treatment of patient with disabling OCD
A multidisciplinary team led by a geneticist and psychiatrist from CSHL's Stanley Institute for Cognitive Genomics have published a paper providing a glimpse of both the tremendous power and the current limitations of "precision medicine."
National Institutes of Health, Stanley Institute for Cognitive Genomics

Contact: Peter Tarr
Cold Spring Harbor Laboratory

Public Release: 3-Oct-2013
Analysis of little-explored regions of genome reveals dozens of potential cancer triggers
A massive data analysis of natural genetic variants in humans and variants in cancer tumors has implicated dozens of mutations in the development of breast and prostate cancer, a Yale-led team has found. The newly discovered mutations are in regions of DNA that do not code for proteins but instead influence activity of other genes. These areas represent an unexplored world that will allow researchers and doctors to gain new insight into the causes and treatment of cancer, said the scientists.
National Institutes of Health

Contact: Bill Hathaway
Yale University

Public Release: 2-Oct-2013
NIH awards grant for new NYU step program created to bolster biomedical research training
The National Institutes of Health has awarded a five-year grant to Keith J. Micoli, postdoctoral program director, NYU School of Medicine, Sackler Institute of Graduate Biomedical Sciences, and Carol Shoshkes Reiss, professor, Departments of Biology and Neural Science at NYU, to enhance the training of biomedical graduate students and postdoctoral scholars to prepare them for a wide range of careers.
National Institutes of Health

Contact: James Devitt
New York University

Showing releases 3426-3450 out of 3477.

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