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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3426-3450 out of 3466.

<< < 133 | 134 | 135 | 136 | 137 | 138 | 139 > >>

Public Release: 26-Sep-2013
Cell Reports
Made to order at the synapse: Dynamics of protein synthesis at neuron tip
Protein synthesis in nerve cell dendrites underlies long-term memory formation in the brain, among other functions. Knowing how proteins are made to order at the synapse can help researchers better understand how memories are made. RNA translation is dictated by translational hotspots, where translation is occurring in a ribosome at any one time in a discrete spot.
NIH/National Institute of Mental Health, Ellison Foundation, National Alliance for Research in Schizophrenia and Affective Disorders, Swedish Research Council

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 26-Sep-2013
Key cellular mechanism in the body's 'battery' can either spur or stop obesity
Becoming obese or remaining lean can depend on the dynamics of the mitochondria, the body's energy-producing "battery," according to two new studies by Yale School of Medicine researchers featured as the cover story in the Sept. 26 issue of the journal Cell.
National Institutes of Health, American Diabetes Association, Helmholtz Society

Contact: Karen N. Peart
Yale University

Public Release: 26-Sep-2013
Bone hormone influences brain development and cognition
Researchers have found that the skeleton, acting through the bone-derived hormone osteocalcin, exerts a powerful influence on prenatal brain development and cognitive functions such as learning, memory, anxiety, and depression in adult mice. Findings from the mouse study could lead to new approaches to the prevention and treatment of neurologic disorders. The study was published today in the online edition of Cell.
NIH/National Institute on Aging, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, Sanofi Aventis, Human Frontier Scientific Program, Director's Pioneer Award

Contact: Karin Eskenazi
Columbia University Medical Center

Public Release: 26-Sep-2013
Nature Genetics
Pan-cancer studies find common patterns shared by different tumor types
Molecular analysis now shows that cancers of different organs have many shared features, while cancers from the same organ or tissue are often quite distinct. The Pan-Cancer Initiative, a major effort to analyze the molecular aberrations in cancer cells across a range of tumor types, has yielded an abundance of new findings.
NIH/National Cancer Institute, NIH/National Human Genome Research Institute

Contact: Tim Stephens
University of California - Santa Cruz

Public Release: 26-Sep-2013
A genetic map for complex diseases
University of Chicago scientists have created one of the most expansive analyses to date of the genetic factors at play in complex diseases such as autism and heart disease by using diseases with known genetic causes to guide them. Identifying trends of co-occurrence among hundreds of diseases in 120 million patients, they created a unique genetic map that has the potential to help diagnose, identify risk factors for and someday develop therapies against complex diseases.
National Institutes of Health

Contact: Kevin Jiang
University of Chicago Medical Center

Public Release: 25-Sep-2013
Infection and Immunity
Researchers develop model to study human response to infections that cause peptic ulcers
Virginia Tech esearchers have developed a model that helps scientists and clinicians understand that complex interactions of a type of bacteria that is the leading cause of peptic ulcers. The discovery may inform changes in the ways doctors treat patients. An estimated 4 million Americans have peptic ulcers.
National Institutes of Health

Contact: Tiffany Trent
Virginia Tech

Public Release: 25-Sep-2013
Cancer Research
New approach to treating human brain cancer could lead to improved outcomes
A new approach to treating medulloblastoma has been developed by researchers at Sanford-Burnham. The method targets cancer stem cells--the cells that are critical for maintaining tumor growth--and halts their ability to proliferate by inhibiting enzymes that are essential for tumor progression. The process destroys the ability of the cancer cells to grow and divide, paving the way for a new type of treatment for patients with this disease.
NIH/National Cancer Institute, NIH/National Institute for Neurological Diseases and Stroke

Contact: Susan Gammon, Ph.D.
Sanford-Burnham Medical Research Institute

Public Release: 25-Sep-2013
Wayne State receives $1.57 million grant to develop enhanced radiation therapy training
With the help of a five-year, $1.57 million grant from the National Cancer Institute of the National Institutes of Health, researchers at Wayne State University aim to develop an innovative and advanced education program integrating radiobiology with radiation physics for all oncologists.
NIH/National Cancer Institute

Contact: Julie O'Connor
Wayne State University - Office of the Vice President for Research

Public Release: 25-Sep-2013
Science Translational Medicine
Researchers use nanoparticles to deliver vaccines to lungs
Particles that deliver vaccines directly to mucosal surfaces could defend against many infectious diseases.
NIH/National Cancer Institute

Contact: Andrew Carleen
Massachusetts Institute of Technology

Public Release: 25-Sep-2013
JAMA Psychiatry
Indiana University study shines new light on consequences of preterm births
A new study by Indiana University Bloomington researchers confirms the strong link between preterm birth and the risk of infant and young adult death, autism and ADHD. But it also suggests that other threats that have been closely tied to the issue, such as severe mental illness, learning problems, suicide and economic woes, may instead be more closely related to other conditions that family members share.
NIH/National Institute of Child Health and Human Development

Contact: Liz Rosdeitcher
Indiana University

Public Release: 25-Sep-2013
Environmental Science & Technology
Flame retardants in blood drop after state ban
A class of flame retardants that has been linked to learning difficulties in children has rapidly declined in pregnant women's blood since the chemicals were banned in California a decade ago, according to a study led by researchers at UC San Francisco.
Passport Foundation Science Innovation Fund, NIH/National Institute of Environmental Health Sciences

Contact: Laura Kurtzman
University of California - San Francisco

Public Release: 24-Sep-2013
How the gut got its villi
The principles guiding the growth of intestinal structures called villi are surprisingly similar across chickens, frogs, mice, and snakes. The wrinkling of the inner gut, the researchers found, is intimately linked to the stages of muscle layer differentiation, which produce a series of different physical stresses.
National Institutes of Health, MacArthur Foundation, Academy of Finland

Contact: Caroline Perry
Harvard University

Public Release: 24-Sep-2013
Clinical Cancer Research
MicroRNA-31 might predict lung-cancer spread
A new study suggests that measuring levels of miR-31 in tumor tissue might accurately determine whether the most common form of lung cancer has spread to nearby lymph nodes. The findings could lead to improvements in the ability of doctors to stage and treat certain patients with non-small cell lung cancer.
NIH/National Center for Advancing Translational Sciences

Contact: Darrell E. Ward
Ohio State University Wexner Medical Center

Public Release: 24-Sep-2013
2013 Annual Scientific Meeting of the Heart Failure Society of America
Living better with heart failure by changing what you eat
Just 21 days of following a low-sodium DASH diet lowered blood pressure and improved heart function for older adults living with a common type of heart failure.
National Institutes of Health

Contact: Shantell M. Kirkendoll
University of Michigan Health System

Public Release: 24-Sep-2013
4-year repeat of bone mineral density screening in seniors offers limited value
Repeating bone mineral density tests after four years provides little clinical benefit when assessing bone fracture risk in seniors age 75 and older, according to a recent study led by researchers at the Harvard Medical School-affiliated Institute for Aging Research at Hebrew SeniorLife.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Disease

Contact: Jennifer Davis
Hebrew SeniorLife Institute for Aging Research

Public Release: 24-Sep-2013
Journal of Abnormal Psychology
Past weight loss an overlooked factor in disordered eating
The focus of eating disorder research has largely been on the state of patients' thoughts, beliefs and emotions, with historically little focus on how current and past body weights contribute. A flurry of studies, the most recent published in the Journal of Abnormal Psychology, suggest that past body weight and relative weight loss should be taken into account.
NIH/National Institute of Mental Health

Contact: Rachel Ewing
Drexel University

Public Release: 24-Sep-2013
Journal of Biological Chemistry
Scientists discover possible way to turn fungus from foe to friend
Candida albicans is a double agent: In most of us, it lives peacefully, but for people whose immune systems are compromised by HIV or other severe illnesses, it is frequently deadly. Now a new study from Johns Hopkins and Harvard Medical School shows how targeting a specific fungal component might turn the fungus from a lion back into a kitten. Study results were reported this month in The Journal of Biological Chemistry.
NIH/National Institute of Allergy and Infectious Diseases, NIH/Search Results National Institute of General Medical Sciences, NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Shawna Williams
Johns Hopkins Medicine

Public Release: 24-Sep-2013
Study confirms that rare mutations increase risk of late-onset Alzheimer's disease
Massachusetts General Hospital researchers have identified and validated two rare gene mutations that appear to cause the common form of Alzheimer's disease (AD) that strikes after the age of 60. The two mutations occur in a gene called ADAM10, which now becomes the second pathologically-confirmed gene for late-onset AD and the fifth AD gene overall.
Cure Alzheimer's Fund, NIH/National Institute on Aging, NIH/National Institute for Mental Health, American Health Assistance Foundation

Contact: Mike Morrison
Massachusetts General Hospital

Public Release: 24-Sep-2013
Journal of Neuroscience
A shot of anxiety and the world stinks
In evolutionary terms, smell is among the oldest of the senses. In animals ranging from invertebrates to humans, olfaction exerts a primal influence as the brain continuously and subconsciously processes the steady stream of scent molecules that waft under our noses.
National Institutes of Health

Contact: Wen Li
University of Wisconsin-Madison

Public Release: 24-Sep-2013
Nature Communications
Adjusting bacteria in intestines may lead to obesity treatments
A drug that appears to target specific intestinal bacteria in the guts of mice may create a chain reaction that could eventually lead to new treatments for obesity and diabetes in humans, according to a team of researchers.
Center for Cancer Research, National Institutes of Health, Pennsylvania Department of Health Research

Contact: Matthew Swayne
Penn State

Public Release: 24-Sep-2013
Arthritis & Rheumatism
Recommendations guide physicians in treatment of systemic juvenile arthritis
In the US, there are nearly 300,000 children with juvenile arthritis and other rheumatic illnesses according to estimates from the American College of Rheumatology. For pediatric patients with systemic juvenile idiopathic arthritis (JIA), effective treatment for this disabling disease is imperative. New treatment recommendations that guide physicians caring for children with systemic JIA are now published in the ACR journals, Arthritis & Rheumatism and Arthritis Care & Research.
American College of Rheumatology, National Institutes of Health, Agency for Healthcare Research and Quality

Contact: Dawn Peters

Public Release: 24-Sep-2013
Journal of Clinical Investigation
Development of autoimmunity in patients with common variable immune deficiency
In this issue of the Journal of Clinical Investigation, Eric Meffre and colleagues at Yale University evaluated B cell activation and tolerance development in healthy individuals and CVID patients with one or two mutated copies of TACI.
NIH/National Institute of Allergy and Infectious Diseases, NIH/National Institute of Child Health and Human Development, Sigrid Juselius Foundation, Finnish Medical Foundation

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 24-Sep-2013
Child Development
Playing with blocks may help children's spatial and math thinking
Playing with blocks may help preschoolers develop the kinds of skills that support later learning in science, technology, engineering, and math, according to a new study that examined over a hundred three-year-olds of various socioeconomic levels. Researchers emphasized the importance of the study's implications because block building and puzzle play can improve children's spatial skills that in turn support complex mathematical problem solving in middle and high school.
National Institutes of Health, National Science Foundation

Contact: Sarah Mandell
Society for Research in Child Development

Public Release: 24-Sep-2013
Child Development
Responsive interactions key to toddlers' ability to learn language
Responsive interactions are the key to toddlers' ability to learn language, according to a new study. Researchers studied 36 two-year-olds, who learned new verbs either through training with a live person, live video chat technology such as Skype, or prerecorded video instruction. Children learned new words only when conversing with a person live and in the video chat, both of which involve responsive social interactions, thus highlighting the importance of responsive interactions for language learning.
NIH/Eunice Kennedy Shriver National Institute of Child Health, National Science Foundation

Contact: Sarah Mandell
Society for Research in Child Development

Public Release: 23-Sep-2013
Journal of Immunological Methods
UT Arlington researchers successfully test model for implant device reactions
A team from the University of Texas at Arlington has used mathematical modeling to develop a computer simulation they hope will one day improve the treatment of dangerous reactions to medical implants such as stents, catheters and artificial joints. Results from their computational model of foreign-body reactions to implants were consistent with biological models in lab tests. A new paper describing the results has been accepted for publication in the Journal of Immunological Methods.
National Institutes of Health

Contact: Traci Peterson
University of Texas at Arlington

Showing releases 3426-3450 out of 3466.

<< < 133 | 134 | 135 | 136 | 137 | 138 | 139 > >>


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