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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3426-3450 out of 3702.

<< < 133 | 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 | 142 > >>

Public Release: 2-Nov-2014
Nature Methods
New technique efficiently turns antibodies into highly tuned 'nanobodies'
A new system, developed by researchers at Rockefeller University and their collaborators, promises to make nanobodies -- antibodies' tiny cousins -- dramatically more accessible for all kinds of research.
National Institutes of Health

Contact: Zach Veilleux
Rockefeller University

Public Release: 2-Nov-2014
Nature Genetics
Mutant models
Using mathematical toolkits traditionally considered the property of statistical physics and artificial intelligence, researchers have developed a way to identify important cancer mutations. This approach can model the effects that cancer mutations have on the intricate patterns of communication between groups of proteins involved in cell signaling. The model shows how mutations can alter signaling networks and points the way to a better understanding of cancer genomes.
National Institutes of Health

Contact: David Cameron
Harvard Medical School

Public Release: 2-Nov-2014
Nature Photonics
Improving imaging of cancerous tissues by reversing time
Lihong Wang, Ph.D., the Gene K. Beare Distinguished Professor of Biomedical Engineering at the School of Engineering & Applied Science is applying a novel time-reversal technology that allows researchers to better focus light in tissue, such as muscles and organs.
National Institutes of Health

Contact: Julie Flory
Washington University in St. Louis

Public Release: 2-Nov-2014
Study: 'Wimpy' antibody protects against kidney disease in mice
An antibody abundant in mice and previously thought to offer poor assistance in fighting against infection may actually play a key role in keeping immune responses in check and preventing more serious self-inflicted forms of kidney disease, according to research at the University of Cincinnati.
US Department of Veterans Affairs Merit Award, National Institutes of Health, University of Cincinnati and Cincinnati Children's Hospital Medical Center

Contact: Cedric Ricks
University of Cincinnati Academic Health Center

Public Release: 1-Nov-2014
American Journal of Respiratory and Critical Care Medicine
More penalties on the way for hospitals that treat the poor? New U-M study suggests so
The federal government will fine more than 2,600 hospitals in the coming year, because too many Medicare patients treated at these hospitals for chronic lung disease and other conditions are ending up back in the hospital within 30 days of going home. Now, a new University of Michigan analysis shows that penalties for chronic lung disease will have a greater impact on hospitals that care for poor and minority patients.
National Institutes of Health, Agency for Healthcare Research and Quality

Contact: Kara Gavin
University of Michigan Health System

Public Release: 31-Oct-2014
168th Meeting of the Acoustical Society of America
Are my muscular dystrophy drugs working?
People with muscular dystrophy could one day assess the effectiveness of their medication with the help of a smartphone-linked device, a new study in mice suggests. The study used a new method to process ultrasound imaging information that could lead to hand-held instruments that provide fast, convenient medical information.
National Institutes of Health, National Science Foundation

Contact: Mary Beckman
DOE/Pacific Northwest National Laboratory

Public Release: 31-Oct-2014
PLOS Pathogens
Immune cells proposed as HIV hideout don't last in primate model
New research from Yerkes National Primate Research Center, Emory University, sheds light on the question of which cells support viral replication and persistence, and the answers have implications for future efforts to eliminate HIV from the body in human patients.
NIH/National Institute of Allergy and Infectious Disease

Contact: Lisa Newbern
Emory Health Sciences

Public Release: 31-Oct-2014
Transforming 'big data' into knowledge
The HMS Center for Biomedical Informatics has received two major government grants totaling nearly $28 million. This new infusion of support will enable the center to continue two major foci of study, one involving neuropsychiatric illness and the other involving new approaches to precision medicine.
NIH/National Human Genome Research Institute, NIH/National Institute for Mental Health, NIH/Common Fund

Contact: David Cameron
Harvard Medical School

Public Release: 31-Oct-2014
Cell division, minus the cells
Researchers have reconstituted cell division -- complete with signals that direct molecular traffic -- without the cell. Combining frog-egg extracts with lipid membranes that mimic the membrane of the cell, they built a cell-free system that recapitulates how the cleavage furrow is assembled.
National Institutes of Health, Marine Biological Laboratory/Evans Foundation

Contact: David Cameron
Harvard Medical School

Public Release: 31-Oct-2014
Broad Institute, Univ. of California team awarded NCI Cancer Genomics Cloud Pilot contract
A team from the Broad Institute, the University of California, Berkeley, and the University of California, Santa Cruz, was awarded one of three National Cancer Institute Cancer Genomics Cloud Pilot contracts with the goal of building a system that will enable large-scale analysis of The Cancer Genome Atlas and other datasets by co-locating the data and the required computing resources in one cloud environment.
NIH/National Cancer Institute

Contact: Haley Bridger
Broad Institute of MIT and Harvard

Public Release: 31-Oct-2014
Improved mouse model will accelerate research on potential Ebola vaccines, treatments
Researchers at the University of North Carolina at Chapel Hill and colleagues have developed the first genetic strain of mice that can be infected with Ebola and display symptoms similar to those that humans experience. This work, published in the current issue of Science, will significantly improve basic research on Ebola treatments and vaccines, which are desperately needed to curb the worldwide public health and economic toll of the disease.
NIH/National Institute of Allergy and Infectious Diseases/Intramural Research Program

Contact: Thania Benios
University of North Carolina at Chapel Hill

Public Release: 31-Oct-2014
UT Southwestern Microbiologist awarded prestigious NIH research grant
Dr. John Schoggins, assistant professor of microbiology at UT Southwestern Medical Center, has received a prestigious New Innovator Award from the National Institutes of Health.
National Institutes of Health

Contact: Deborah Wormser
UT Southwestern Medical Center

Public Release: 31-Oct-2014
Cancer Research
Viewing cancer on the move: New device yields close-up look at metastasis
Johns Hopkins engineers have invented a lab device to give cancer researchers an unprecedented microscopic look at metastasis, the complex way that tumor cells spread through the body, causing more than 90 percent of cancer-related deaths.
Johns Hopkins University Institute for NanoBioTechnology, National Institutes of Health

Contact: Phil Sneiderman
Johns Hopkins University

Public Release: 30-Oct-2014
Journal of Lipid Research
Researchers probe link between newborn health and vitamin A
The impact vitamin A has on newborns is virtually unknown, but Penn State nutrition researchers have published two papers that may provide a framework for future investigations of the vitamin and neonatal health.
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development

Contact: Victoria M. Indivero
Penn State

Public Release: 30-Oct-2014
Proceedings of the National Academy of Sciences
Heart's own immune cells can help it heal
The heart holds its own pool of immune cells capable of helping it heal after injury, according to new research in mice at Washington University School of Medicine in St. Louis.
National Institutes of Health, Oliver Langenberg Physician-Scientist Training Program, Washington University Center for the Investigation of Membrane Excitability Diseases Live Cell Imaging Facility

Contact: Julia Evangelou Strait
Washington University School of Medicine

Public Release: 30-Oct-2014
Proceedings of the National Academy of Sciences
Making lab-grown tissues stronger
Lab-grown tissues could one day provide new treatments for injuries and damage to the joints, including articular cartilage, tendons and ligaments.
National Institutes of Health

Contact: Andy Fell
University of California - Davis

Public Release: 30-Oct-2014
Archives of Physical Medicine and Rehabilitation
Study shows vibrating insoles could reduce falls among seniors
Findings published in the Archives of Physical Medicine and Rehabilitation show that imperceptible vibratory stimulation applied to the soles of the feet improved balance by reducing postural sway and gait variability in elderly study participants. The vibratory stimulation is delivered by a urethane foam insole with embedded piezoelectric actuators, which generates the mechanical stimulation.
Merck Sharpe and Dohme Consumer Care, Inc., NIH/National Institute on Aging, Wyss Institute for Biologically Inspired Engineering at Harvard University

Contact: Jennifer Davis
Peters Communications

Public Release: 30-Oct-2014
PLOS Genetics
Identifying the source of stem cells
When most animals begin life, cells immediately begin accepting assignments to become a head, tail or a vital organ. However, mammals, including humans, are special. The cells of mammalian embryos get to make a different first choice -- to become the protective placenta or to commit to forming the baby.
National Institutes of Health

Contact: Layne Cameron
Michigan State University

Public Release: 30-Oct-2014
Cell Reports
Blocking a fork in the road to DNA replication
A team of Whitehead Institute scientists has discovered the surprising manner in which an enigmatic protein known as SUUR acts to control gene copy number during DNA replication. It's a finding that could shed new light on the formation of fragile genomic regions associated with chromosomal abnormalities.
National Institutes of Health, American Cancer Society, Damon Runyon Cancer Research Foundation

Contact: Matt Fearer
Whitehead Institute for Biomedical Research

Public Release: 30-Oct-2014
Why scratching makes you itch more
Turns out your mom was right: scratching an itch only makes it worse. New research from scientists at the Center for the Study of Itch at Washington University School of Medicine in St. Louis reveals that scratching causes the brain to release serotonin, which intensifies the itch sensation.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH/National Institute on Drug Abuse, NIH/National Institute of General Medical Sciences

Contact: Jim Dryden
Washington University School of Medicine

Public Release: 30-Oct-2014
Hygienic funerals, better protection for health workers offer best chance to stop Ebola
Hygienic funeral practices, case isolation, contact tracing with quarantines, and better protection for health care workers are the keys to stopping the Ebola epidemic that continues to expand in West Africa, researchers said today in a new report in the journal Science. They said broad implementation of aggressive measures they recommend could lead to its control in Liberia, the focal point, by mid-March.
National Institutes of Health

Contact: Jan Medlock
Oregon State University

Public Release: 30-Oct-2014
Molecular Cell
Rewiring cell metabolism slows colorectal cancer growth
A University of Utah-led study reports that cancers select against a protein complex called the mitochondrial pyruvate carrier, and re-introduction of MPC in colon cancer cells impairs several properties of cancer, including growth. The research, which appears online on Oct. 30 in Molecular Cell, implicates changes in a key step in metabolism -- the way cellular fuel is utilized -- as an important driver of colon cancer that is also likely to be important in many other cancer settings.
National Institutes of Health, Nora Eccles Treadwell Foundation

Contact: Julie Kiefer
University of Utah Health Sciences

Public Release: 30-Oct-2014
Scripps Research Institute scientists capture picture of 'MicroRNA' in action
Biologists at The Scripps Research Institute have described the atomic-level workings of 'microRNA' molecules, which control the expression of genes in all animals and plants. The findings add greatly to the understanding of a fundamental system of regulation in biology, and should accelerate the development of therapies that harness its power.
National Institutes of Health

Contact: Madeline McCurry-Schmidt
Scripps Research Institute

Public Release: 30-Oct-2014
What's mighty about the mouse? For starters, its massive Y chromosome
An exhaustive effort to sequence the mouse Y chromosome reveals a surprisingly large and complex biological beast, at the same time providing remarkable insight into a heated battle for supremacy between mammalian sex chromosomes.
National Institutes of Health, Howard Hughes Medical Institute

Contact: Matt Fearer
Whitehead Institute for Biomedical Research

Public Release: 30-Oct-2014
Genetic factors behind surviving or dying from Ebola shown in mouse study
A newly developed mouse model suggests that genetic factors are behind the mild-to-deadly range of responses to the Ebola virus. The frequency of different manifestations of the disease across the lines of these mice are similar in variety and proportion to the spectrum of clinical disease observed in the 2014 West African outbreak. The new mouse model might be useful in testing candidate therapeutics and vaccines for Ebola, and in finding genetic markers for susceptibility and resistance to the disease.
National Institutes of Health, NIH/National Institute of Allergy and Infectious Diseases, Office of NIH Director

Contact: Leila Gray
University of Washington Health Sciences/UW Medicine

Showing releases 3426-3450 out of 3702.

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