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Key: Meeting M      Journal J      Funder F

Showing releases 3451-3475 out of 3754.

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Public Release: 7-Aug-2014
Nature Communications
Cell mechanics may hold key to how cancer spreads and recurs
Cancer cells that break away from tumors to go looking for a new home may prefer to settle into a soft bed, according to new findings from researchers at the University of Illinois. Some particularly enterprising cancer cells can cause a cancer to spread to other organs or evade treatment to resurface after a patient is thought to be in remission. The researchers found that these tumor-repopulating cells may lurk quietly in stiffer cellular environments, but thrive in a softer space.
National Institutes of Health

Contact: Liz Ahlberg
University of Illinois at Urbana-Champaign

Public Release: 7-Aug-2014
American Journal of Medicine
Caffeine intake associated with lower incidence of tinnitus
New research from Brigham and Women's Hospital finds that higher caffeine intake is associated with lower rates of tinnitus, often described as a ringing or buzzing sound in the ear when there is no outside source of the sounds, in younger and middle-aged women.
National Institutes of Health

Contact: Jessica Maki
Brigham and Women's Hospital

Public Release: 7-Aug-2014
New England Journal of Medicine
UTHealth researchers find infectious prion protein in urine of patients with variant Creutzfeldt-Jakob disease
The misfolded and infectious prion protein that is a marker for variant Creutzfeldt-Jakob disease -- linked to the consumption of infected cattle meat -- has been detected in the urine of patients with the disease by researchers at The University of Texas Health Science Center at Houston Medical School.
National Institutes of Health, Italian Ministry of Health, Associazione Italniana Encfalopatie da Prioni, Minesterio dell'Universita e della Ricerca, Charles S. Britton Fund, British Department of Health

Contact: Deborah Mann Lake
University of Texas Health Science Center at Houston

Public Release: 7-Aug-2014
Kentucky professor develops new tool to prevent heroin deaths
A new, lifesaving product aimed at reducing the death toll from heroin abuse -- developed by a professor at the University of Kentucky College of Pharmacy -- is in its final round of clinical trials and has received Fast Track designation by the Food and Drug Administration. The product, a nasal spray application of the anti-opioid drug naloxone, was developed by Daniel Wermeling, a professor of pharmacy practice and science.
NIH/National Institute on Drug Abuse, Kentucky Science and Technology Corporation

Contact: Keith Hautala
University of Kentucky

Public Release: 7-Aug-2014
Journal of Investigative Dermatology
Acute psychological stress promotes skin healing in mice
Brief, acute psychological stress promoted healing in mouse models of three different types of skin irritations, in a study led by UC San Francisco researchers.
San Francisco VA Medical Center Home, National Institutes of Health

Contact: Jeffrey Norris
University of California - San Francisco

Public Release: 7-Aug-2014
Notch developmental pathway regulates fear memory formation
Researchers at Yerkes National Primate Research Center, Emory University, have learned that the molecule Notch, critical in many processes during embryonic development, is also involved in fear memory formation.
NIH/National Institute of Mental Health

Contact: Quinn Eastman
Emory Health Sciences

Public Release: 7-Aug-2014
Nature Communications
Study shines new light on genetic alterations of aggressive breast cancer subtype
Researchers from the Lester and Sue Smith Breast Center at Baylor College of Medicine have uncovered new information about the genetic alterations that may contribute to the development of a subtype breast cancer typically associated with more aggressive forms of the disease and higher recurrence rates.
US Department of Defense, Nancy Owens Memorial Foundation, Susan G. Komen for the Cure, National Institutes of Health

Contact: Glenna Picton
Baylor College of Medicine

Public Release: 7-Aug-2014
Genome Research
Gut microbes browse along a gene buffet
A detailed examination of gene expression in the guts of mice raised under three different microbial conditions shows that the host organism controls which genes are made available to gut microbes at various portions of the intestine. Usage of particular genes is regulated by the microbes, but access to the genes is determined by the host.
National Institutes of Health, National Science Foundation, PhRMA Foundation, Pew Scholars in the Biomedical Sciences Program

Contact: Karl Leif Bates
Duke University

Public Release: 7-Aug-2014
Stroke: Journal of the American Heart Association
Slowing brain functions linked to increased risk of stroke, death
Declining memory and cognitive ability may increase the risk of stroke in adults over age 65. After stroke, cognitive function declined almost twice as fast. Stroke and cognitive decline increased the risk of death in older adults.
NIH/National Institutes on Aging, NIH/National Institute on Minority Health and Health Disparities, University of Minnesota

Contact: Bridgette McNeill
American Heart Association

Public Release: 7-Aug-2014
Cancer Prevention Research
Gut microbiome analysis improved noninvasive colorectal cancer screening
Analysis of the gut microbiome more successfully distinguished healthy individuals from those with precancerous adenomatous polyps and those with invasive colorectal cancer compared with assessment of clinical risk factors and fecal occult blood testing, according to data published in Cancer Prevention Research, a journal of the American Association for Cancer Research.
National Institutes of Health

Contact: Jeremy Moore
American Association for Cancer Research

Public Release: 7-Aug-2014
Largest cancer genomic study proposes 'disruptive' new system to reclassify tumors
After analyzing more than 3,500 tumors on multiple technology platforms TCGA researchers say cancers are more likely to be similar based on their cell type of origin as opposed to their tissue type of origin. The study suggests at least 10 percent of cancer patients would be classified differently under this protocol. But Buck faculty Christopher Benz thinks this fraction will swell when more samples and additional tumor types are included in the next analysis.
NIH/National Cancer Institute, NIH/National Human Genome Research Institute

Contact: Kris Rebillot
Buck Institute for Age Research

Public Release: 7-Aug-2014
Cancer study reveals powerful new system for classifying tumors
Cancers are classified primarily on the basis of where in the body the disease originates, as in lung cancer or breast cancer. According to a new study, however, one in 10 cancer patients would be classified differently using a new classification system based on molecular subtypes instead of the current tissue-of-origin system. This reclassification could lead to different therapeutic options for those patients.
National Institutes of Health

Contact: Tim Stephens
University of California - Santa Cruz

Public Release: 7-Aug-2014
Dramatic growth of grafted stem cells in rat spinal cord injuries
Building upon previous research, scientists at the University of California, San Diego School of Medicine and Veteran's Affairs San Diego Healthcare System report that neurons derived from human induced pluripotent stem cells and grafted into rats after a spinal cord injury produced cells with tens of thousands of axons extending virtually the entire length of the animals' central nervous system.
Veterans Administration, National Institutes of Health, Craig H. Neilsen Foundation, California Institute for Regenerative Medicine, Dr. Miriam and Sheldon G. Adelson Medical Research Foundation

Contact: Jackie Carr
University of California - San Diego

Public Release: 6-Aug-2014
Nature Biotechnology
Single-cell analysis holds promise for stem cell and cancer research
UC San Francisco researchers have identified cells' unique features within the developing human brain, using the latest technologies for analyzing gene activity in individual cells, and have demonstrated that large-scale cell surveys can be done much more efficiently and cheaply than was previously thought possible.
Damon Tunyon Cancer Research Foundation, California Institute for Regenerative Medicine, National Institutes of Health

Contact: Jeffrey Norris
University of California - San Francisco

Public Release: 6-Aug-2014
Biology Letters
Galápagos hawks hand down lice like family heirlooms
Studying Galápagos hawks and their lice, a University of Arizona-led research team provides some of the first field evidence for co-divergence between parasites and hosts as a major driver of biodiversity. As the birds diversify into distinct populations on each island, their parasites diversify with them. The findings help explain the rapid rate of parasite evolution.
National Science Foudnation, Saint Louis Zoo/Field Research for Conservation, University of Missouri Research Board, John Templeton Foundation, University of Arizona, National Institutes of Health

Contact: Daniel Stolte
University of Arizona

Public Release: 6-Aug-2014
Cancer Research
Brain tumors fly under the body's radar like stealth jets, new U-M research suggests
Brain tumors fly under the radar of the body's defense forces by coating their cells with extra amounts of a specific protein, new research shows. Like a stealth fighter jet, the coating means the cells evade detection by the early-warning immune system that should detect and kill them. The stealth approach lets the tumors hide until it's too late for the body to defeat them.
NIH/National Institute of Neurological Disorders & Stroke

Contact: Kara Gavin
University of Michigan Health System

Public Release: 6-Aug-2014
A new way to model cancer
New gene-editing technique from researchers at MIT allows scientists to more rapidly study the role of mutations in tumor development.
National Institutes of Health, NIH/National Cancer Institute

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 6-Aug-2014
Proceedings of the National Academy of Sciences
Discovery yields master regulator of toxin production in staph infections
St. Jude Children's Research Hospital scientists have discovered an enzyme that regulates production of the toxins that contribute to potentially life-threatening Staphylococcus aureus infections. The study recently appeared in the scientific journal the Proceedings of the National Academy of Sciences. Researchers also showed that the same enzyme allows Staphylococcus aureus to use fatty acids acquired from the infected individual to make the membrane that bacteria need to grow and flourish.
National Institutes of Health, NIH/National Cancer Institute, American Lebanese Syrian Associated Charities

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Public Release: 6-Aug-2014
Stowers researchers reveal molecular competition drives adult stem cells to specialize
Adult organisms ranging from fruit flies to humans harbor adult stem cells, some of which renew themselves through cell division while others differentiate into the specialized cells needed to replace worn-out or damaged organs and tissues. Understanding the molecular mechanisms that control the balance between self-renewal and differentiation in adult stem cells is an important foundation for developing therapies to regenerate diseased, injured or aged tissue.
The Stowers Institute for Medical Research, National Natural Science Foundation of China, Ministry of Science and Technology of China, National Institutes of Health

Contact: Kim Bland, Ph.D.
Stowers Institute for Medical Research

Public Release: 5-Aug-2014
Biology made simpler with clear tissues
Thanks to techniques developed at Caltech, scientists can see through tissues, organs, and even an entire body. The techniques offer new insight into the cell-by-cell makeup of organisms -- and the promise of novel diagnostic medical applications.
NIH/National Institute of Neurological Disorders and Stroke, National Institutes of Health, The Beckman Institute of Caltech, Pew Charitable Trust, Sidney Kimmel Foundation

Contact: Deborah Williams-Hedges
California Institute of Technology

Public Release: 5-Aug-2014
Nucleic Acids Research
'Treatments waiting to be discovered' inside new database
A University of Colorado Cancer Center study recently published in the top-ranked journal Nucleic Acids Research describes a database named multiMiR, the most comprehensive database collecting information about microRNAs and their targets.
National Institutes of Health, NIH/National Cancer Institute

Contact: Garth Sundem
University of Colorado Anschutz Medical Campus

Public Release: 5-Aug-2014
Optics Express
Watching chemistry in motion: Chemical environments mapped using molecular vibrations
Scientists have long known that a molecule's behavior depends on its environment. Taking advantage of this phenomenon, a group of researchers at the University of Chicago developed a new technique to map microscopic environments using the vibrations of molecules.
National Science Foundation, National Institutes of Health, Deutsche Forschungsgemeinschaft

Contact: Steve Koppes
University of Chicago

Public Release: 5-Aug-2014
Journal of the American Heart Association
Pistachios may lower vascular response to stress in type 2 diabetes
Among people with type 2 diabetes, eating pistachios may reduce the body's response to the stresses of everyday life, according to Penn State researchers.
American Pistachio Growers, National Institutes of Health

Contact: A'ndrea Elyse Messer
Penn State

Public Release: 5-Aug-2014
Experimental Biology and Medicine
Pyruvate oxidation is critical determinant of pancreatic islet number and β-cell mass
Glucose is not only a major nutrient regulator of insulin secretion but also impacts on gene expression in β-cells. Using a mouse model of β-cell-specific knock-out of Pdha1 gene which encodes the α subunit of the pyruvate dehydrogenase component of the pyruvate dehydrogenase complex, the authors demonstrated that mitochondrial metabolism of pyruvate derived from glucose not only regulates insulin secretion but also directly influences β-cell growth and plasticity.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Canadian Institute of Health Research

Contact: M.S. Patel
Society for Experimental Biology and Medicine

Public Release: 5-Aug-2014
Journal of Family Psychology
Marital tension between mom and dad can harm each parent's bond with child, study finds
Children suffer when mom and dad have problems in their marriage, according to a new study. Dads, especially, let negative emotions and tension from their marriage spill over and harm the bond with their child, says psychologist and lead-author Chrystyna Kouros, Southern Methodist University, Dallas. Conversely, moms in poor quality marriages sometimes compartmentalized marital tension and improved the relationship with their child. The findings indicate marriage quality closely affects the parent-child bond, Kouros said.
NIH/National Institute of Child Health and Human Development

Contact: Margaret Allen
Southern Methodist University

Showing releases 3451-3475 out of 3754.

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