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Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3451-3475 out of 3555.

<< < 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 | 142 | 143 > >>

Public Release: 11-Jan-2014
Journal of Behavioral and Developmental Pediatrics
Complementary medicine in wide use to treat children with autism, developmental delay
In a study of the range of treatments being employed for young children with autism and other developmental delays, UC Davis MIND Institute researchers have found that families often use complementary and alternative medicine treatments and that the most frequent users of both conventional and complementary approaches are those with higher levels of parental education and income.
NIH/National Institute of Environmental Health Sciences, US Environmental Protection Agency

Contact: Phyllis Brown
University of California - Davis Health System

Public Release: 10-Jan-2014
Nature Cell Biology
Study: Autophagy predicts which cancer cells live and die when faced with anti-cancer drugs
When a tumor is treated with an anti-cancer drug, some cells die and, unfortunately, some cells tend to live. A University of Colorado Cancer Center study published in the journal Nature Cell Biology details a possible difference between the susceptible and resistant cells: the rate at which cells are able to cleanse themselves via the process known as autophagy.
National Institutes of Health

Contact: Garth Sundem
University of Colorado Denver

Public Release: 9-Jan-2014
Journal of the National Cancer Institute
Researchers develop tool to determine individual risk of prostate cancer overdiagnosis
Studies have found that prostate cancer is overdiagnosed in up to 42 percent of cases, prompting men to receive unnecessary treatment that can cause devastating side effects, including impotence and incontinence. Now, researchers at Fred Hutchinson Cancer Research Center and the University of Washington have developed a personalized tool that can predict the likelihood of prostate cancer overdiagnosis.
NIH/National Cancer Institute, Centers for Disease Control and Prevention

Contact: Deborah Bach
Fred Hutchinson Cancer Research Center

Public Release: 9-Jan-2014
JAMA Psychiatry
Novel biomarker approach suggests new avenues to improve schizophrenia disease management
Environmental effects of events such as oxygen deprivation and infections may be preserved as markers in blood that are associated to schizophrenia, according to an international study led by the Virginia Commonwealth University School of Pharmacy's Center for Biomarker Research and Personalized Medicine.
NIH/National Institute of Mental Health

Contact: Eric Peters
Virginia Commonwealth University

Public Release: 9-Jan-2014
Journal of Clinical Investigation
Antipsychotic drug exhibits cancer-fighting properties
In a prime example of finding new uses for older drugs, studies in zebrafish show that a 50-year-old antipsychotic medication called perphenazine can actively combat the cells of a difficult-to-treat form of acute lymphoblastic leukemia, according to a study published in the Journal of Clinical Investigation. The drug works by turning on a cancer-suppressing enzyme called PP2A and causing malignant tumor cells to self-destruct.
NIH/National Cancer Institute, Leukemia & Lymphoma Society, and others

Contact: Irene Sege
Dana-Farber Cancer Institute

Public Release: 9-Jan-2014
Proceedings of the National Academy of Sciences
Some motor proteins cooperate better than others
A study at Rice University analyzes how teams of molecular motor proteins cooperate as they move cargoes around living cells.
Welch Foundation, National Institutes of Health

Contact: Jeff Falk
Rice University

Public Release: 9-Jan-2014
Journal of Biological Chemistry
LSUHSC research reveals structure of master regulator and new drug target for autism, cervical cancer
A team of scientists at LSU Health Sciences Center New Orleans has discovered the structure of the active form of E6-associated protein (E6AP), an enzyme that acts as a master regulator, controlling functions like the ability of nerve cells to "rewire" themselves in response to external stimuli and HPV hijacking cells leading to cervical cancer. They report, for the first time, that the active form of E6AP is composed of three distinct protein molecules.
National Institutes of Health

Contact: Leslie Capo
Louisiana State University Health Sciences Center

Public Release: 9-Jan-2014
Red blood cells take on many-sided shape during clotting
Red blood cells are the body's true shape shifters, perhaps the most malleable of all cell types. While studying how blood clots contract researchers discovered a new geometry that red blood cells assume, when compressed during clot formation.
NIH/National Heart, Lung, and Blood Institute

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Public Release: 9-Jan-2014
SHY hypothesis explains that sleep is the price we pay for learning
Why do animals ranging from fruit flies to humans all need to sleep? After all, sleep disconnects them from their environment, puts them at risk and keeps them from seeking food or mates for large parts of the day.
NIH/National Institute of Mental Health

Contact: Susan Lampert Smith
University of Wisconsin-Madison

Public Release: 9-Jan-2014
Journal of Endocrinology and Metabolism
Minorities and poor have more advanced thyroid cancers when diagnosed, UCLA study shows
UCLA researchers have found that minority patients and those of lower socioeconomic status are far more likely to have advanced thyroid cancer when they are diagnosed with the disease than white patients and those in higher economic brackets. In one of the most comprehensive studies of its kind, the UCLA team looked at nearly 26,000 patients with well-differentiated thyroid cancer and analyzed the impact of race and socioeconomic factors on the stage of presentation, as well as patient survival rates.
National Institutes of Health, Clinical Translational and Science Institute

Contact: Rachel Champeau
University of California - Los Angeles Health Sciences

Public Release: 9-Jan-2014
Spinal cord findings could help explain origins of limb control
Northwestern University researchers have found that the spinal cord circuits that produce body bending in swimming fish are more complicated than previously thought. In a study of zebrafish, they report that differential control of an animal's musculature -- the basic template for controlling more complex limbs, such as in humans -- is already in place in the spinal networks of simple fish. The data could help clarify how vertebrates made the transition from water to land.
National Institutes of Health, Alfred P. Sloan Foundation, Esther A. and Joseph Klingenstein Fund

Contact: Megan Fellman
Northwestern University

Public Release: 9-Jan-2014
Scientists uncover new target for brain cancer treatment
A new study is giving researchers hope that novel targeted therapies can be developed for glioblastoma multiforme, the most common and most aggressive form of brain cancer, after demonstrating for the first time that a gene known as melanoma differentiation associated gene-9/syntenin (mda-9/syntenin) is a driving force behind the disease's aggressive and invasive nature.
National Institutes of Health, NIH/National Cancer Institute

Contact: John Wallace
Virginia Commonwealth University

Public Release: 9-Jan-2014
Physical Biology
Researchers develop test to predict early onset of heart attacks
A new "fluid biopsy" technique that could identify patients at high risk of a heart attack by identifying specific cells as markers in the bloodstream has been developed by a group of researchers at the Scripps Research Institute.
NIH/National Center for Research Resources, NIH/National Cancer Institute

Contact: Mika Ono
Scripps Research Institute

Public Release: 9-Jan-2014
Cell Reports
A new pathway for neuron repair is discovered
A brand-new pathway for neuron repair has been discovered that could have implications for faster and improved healing after nerve damage. The research demonstrates, for the first time, that dendrites, the component of nerve cells that receive information from the brain, have the capacity to regrow after an injury.
National Institutes of Health, Pew Charitable Trusts

Contact: Barbara K.Kennedy
Penn State

Public Release: 9-Jan-2014
Developmental Cell
Mystery solved: How nerve impulse generators get where they need to go
Scientists have solved a longstanding mystery of the central nervous system, showing how a key protein gets to the right spot to launch electrical impulses that enable communication of nerve signals to and from the brain.
National Institutes of Health, NIH/National Institute of Neurological Disorders and Stroke

Contact: Chen Gu
Ohio State University

Public Release: 9-Jan-2014
PLOS Pathogens
UNC research demonstrates 'guided missile' strategy to kill hidden HIV
Researchers at the UNC School of Medicine have deployed a potential new weapon against HIV -- a combination therapy that targets HIV-infected cells that standard therapies cannot kill.
National Institutes of Health

Contact: Lisa Chensvold
University of North Carolina Health Care

Public Release: 9-Jan-2014
American Journal of Transplantation
Mass. General research could expand availability of hand, face transplants
Massachusetts General Hospital investigators have made an important step towards greater availability of hand transplants, face transplants and other transplants involving multiple types of tissue. In their report in the American Journal of Transplantation, the team describes how a procedure developed at the MGH to induce immune tolerance to organ transplants also induces tolerance to a model limb transplant in miniature swine.
National Institutes of Health, Musculoskeletal Transplant Foundation, Melina Nakos Foundation

Contact: Kristen Chadwick
Massachusetts General Hospital

Public Release: 9-Jan-2014
Journal of Clinical Investigation
Mice exposed to retinoid deficiency in utero exhibit bronchial hyperresponsiveness as adults
In this issue of the Journal of Clinical Investigation, Wellington Cardoso and colleagues at the Boston University School of Medicine reveal that mice born to mothers with retinoid deficiency during pregnancy are at increased risk of developing airway hyperesponsiveness.
National Institutes of Health

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 9-Jan-2014
Journal of Clinical Investigation
Engineered anti-toxin antibodies improve efficacy
In this issue of the Journal of Clinical Investigation, Jeffrey Ravetch and colleagues at the Rockefeller University demonstrate that engineering the Fc domain of anti-toxin antibodies increases toxin neutralization activity through enhancing the interaction between toxin-targeting antibodies and the Fc receptor on immune cells.
National Institutes of Health, Northeast Biodefense Center

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 8-Jan-2014
Journal of Cerebral Blood Flow and Metabolism
Discovery leads to patent for novel method of treating traumatic brain injury
Dr. James Lechleiter of the UT Health Science Center at San Antonio received a US patent for his discovery that a class of compounds is protective against traumatic brain injury (TBI). Dr. Lechleiter found that two compounds stimulate the ability of the brain's caretaker cells (called astrocytes) to do their job, which includes reducing swelling. It is hoped that preliminary studies will lead to a new class of safe and effective drugs for TBI.
NIH/National Institute on Aging

Contact: Will Sansom
University of Texas Health Science Center at San Antonio

Public Release: 8-Jan-2014
Study identifies risk factors for non-fatal overdoses
Researchers from Boston University School of Medicine and Boston Medical Center have identified that injection frequency and taking anti-retroviral therapy for HIV are risk factors for nonfatal drug overdoses among Russians who are HIV positive and inject drugs.
NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Jenny Eriksen
Boston University Medical Center

Public Release: 8-Jan-2014
Journal of Neuroscience
Nociceptin: Nature's balm for the stressed brain
Collaborating scientists at the Scripps Research Institute, the National Institutes of Health and the University of Camerino in Italy have published new findings on a system in the brain that naturally moderates the effects of stress. The findings confirm the importance of this stress-damping system, known as the nociceptin system, as a potential target for therapies against anxiety disorders and other stress-related conditions.
National Institutes of Health, Pearson Center for Alcoholism & Addiction Research, German Research Foundation

Contact: Mika Ono
Scripps Research Institute

Public Release: 8-Jan-2014
JAMA Psychiatry
Mental disorders in mid-life and older adulthood more prevalent than previously reported
Common methods of assessing mental or physical disorders may consistently underestimate the prevalence of mental disorders among middle-aged and older adults, a new study from the Johns Hopkins Bloomberg School of Public Health has found. The analysis reveals substantial discrepancies among mid-life and late-life adults in reporting past mental health disorders, including depression, compared with physical disorders such as arthritis and hypertension.
NIH/National Institute on Drug Abuse, NIH/National Institute on Alcohol Abuse and Alcoholism

Contact: Tim Parsons
Johns Hopkins University Bloomberg School of Public Health

Public Release: 8-Jan-2014
MARC travel awards announced for the APS 2014 Professional Skills Training Course
THe FASEB MARC (Maximizing Access to Research Careers) Program has announced the travel award recipients for the American Physiological Society Professional Skills Training Course in Orlando, Fla., from Jan. 16-19, 2014.
National Institutes of Health

Contact: Gail Pinder
Federation of American Societies for Experimental Biology

Public Release: 8-Jan-2014
Proceedings of the Royal Society B
Coral chemical warfare: Suppressing a competitor enhances susceptibility to a predator
Competition may have a high cost for at least one species of tropical seaweed. Researchers examining the chemical warfare taking place on Fijian coral reefs have found that one species of seaweed increases its production of noxious anti-coral compounds when placed into contact with reef-building corals, but at the same time becomes more attractive to herbivorous fish.
National Science Foundation, National Institutes of Health

Contact: John Toon
Georgia Institute of Technology

Showing releases 3451-3475 out of 3555.

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