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Key: Meeting M      Journal J      Funder F

Showing releases 3451-3475 out of 3755.

<< < 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 | 142 | 143 > >>

Public Release: 29-Sep-2014
ESMO 2014 Congress
Trial shows trastuzumab should remain as standard of care for HER2-positive breast cancer
Analysis of more than 8,000 women who participated in the world's largest study of two treatments for HER2-positive breast cancer reinforces other findings from the clinical trial showing that trastuzumab, also known as Herceptin, should remain the standard of care for this cancer, says a Mayo Clinic researcher.
Breast Cancer Intergroup of North America, Breast International Group, NIH/National Cancer Institute, Glaxo SmithKline

Contact: Paul Scotti
Mayo Clinic

Public Release: 29-Sep-2014
Proceedings of the National Academy of Sciences
Scripps Research Institute scientists shed light on cause of spastic paraplegia
Scientists at The Scripps Research Institute have discovered that a gene mutation linked to hereditary spastic paraplegia, a disabling neurological disorder, interferes with the normal breakdown of triglyceride fat molecules in the brain. The Scripps researchers found large droplets of triglycerides within the neurons of mice modeling the disease.
National Institutes of Health

Contact: Madeline McCurry-Schmidt
Scripps Research Institute

Public Release: 29-Sep-2014
Proceedings of the National Academy of Sciences
Viral infection might just be a phase... transition
Many double-stranded DNA viruses infect cells by ejecting their genetic information into a host cell. But how does the rigid DNA packaged inside a virus flow into a cell? In two separate studies, Carnegie Mellon biophysicist Alex Evilevitch has shown that in viruses that infect both bacteria and humans, a phase transition at the temperature of infection allows the DNA to change from a rigid crystalline structure into a fluid-like structure that facilitates infection.
Swedish Research Council, National Science Foundation, National Institutes of Health, McWilliams Fellowship at Carnegie Mellon

Contact: Jocelyn Duffy
Carnegie Mellon University

Public Release: 29-Sep-2014
Bulletin of the American Meteorological Society
Causes of California drought linked to climate change
The extreme atmospheric conditions associated with California's crippling drought are far more likely to occur under today's global warming conditions than in the climate that existed before humans emitted large amounts of greenhouse gases, Stanford scientists say.
National Science Foundation, National Institutes of Health, Defense Advanced Research Projects Agency, Air Force Office of Scientific Research, UPS Fund

Contact: Ker Than
Stanford University

Public Release: 29-Sep-2014
Proceedings of the National Academy of Sciences
Research suggests new strategies for killing TB bacterium
Researchers from Brown and MIT have shown new details about how a promising new class of antibiotics attacks the bacterium that causes tuberculosis. The research could provide a blueprint for developing drugs aimed at fighting TB.
National Institutes of Health, Brown University

Contact: Kevin Stacey
Brown University

Public Release: 29-Sep-2014
Healthy fats help diseased heart muscle process and use fuel
Oleate, a common dietary fat found in olive oil, restored proper metabolism of fuel in an animal model of heart failure. The findings are reported in the journal Circulation by researchers at University of Illinois at Chicago College of Medicine.
NIH/National Heart, Lung and Blood Institute, American Heart Association

Contact: Sharon Parmet
University of Illinois at Chicago

Public Release: 29-Sep-2014
After-school exercise program enhances cognition in 7-, 8- and 9-year-olds
A nine-month-long, randomized controlled trial involving 221 prepubescent children found that those who engaged in moderate-to-vigorous physical activity for at least 60 minutes a day after school saw substantial improvements in their ability to pay attention, avoid distraction and switch between cognitive tasks, researchers report in the journal Pediatrics.
NIH/National Institute of Child Health and Human Development

Contact: Diana Yates
University of Illinois at Urbana-Champaign

Public Release: 29-Sep-2014
Proceedings of the National Academy of Sciences
Study reveals new clues to help understand brain stimulation
A new study from Beth Israel Deaconess Medical Center suggests that brain networks -- the interconnected pathways that link brain circuits to one another -- can help guide site selection for brain stimulation therapies.
National Institutes of Health, Sidney R. Baer Jr. Foundation, Michael J. Fox Foundation, National Football League Players Association, American Academy of Neurology/American Brain Foundation, Harvard Catalyst

Contact: Bonnie Prescott
Beth Israel Deaconess Medical Center

Public Release: 29-Sep-2014
Journal of Clinical Oncology
Landmark Medicare law had little impact on reducing chemotherapy cost
Legislation passed in 2003 to slow the spiraling costs of drugs paid for by the federal government to treat Medicare patients has had no meaningful impact on cancer chemotherapy drug costs. In this study, the authors note that not only did the policy fail, cancer care cost has skyrocketed. During the decade after the law passed, the aggregate cost of cancer care increased by as much as 60 percent, even though cancer rates had fallen.
NIH/National Cancer Institute, US Department of Veterans Affairs

Contact: Karen Teber
Georgetown University Medical Center

Public Release: 29-Sep-2014
Scientists discover a new role for estrogen in the pathology of breast cancer
Scientists have discovered a previously unknown mechanism by which estrogen prepares cells to divide, grow and, in the case of estrogen-positive breast cancers, resist cancer drugs. The researchers say the work reveals new targets for breast cancer therapy and will help doctors predict which patients need the most aggressive treatment.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Diana Yates
University of Illinois at Urbana-Champaign

Public Release: 28-Sep-2014
Nature Medicine
Protein that causes frontotemporal dementia also implicated in Alzheimer's disease
Low levels of the naturally occurring protein progranulin exacerbate cellular and cognitive dysfunction, while raising levels can prevent abnormalities in an Alzheimer's model.
Consortium for Frontotemporal Dementia, National Institutes of Health, S.D. Bechtel, Jr. Foundation

Contact: Dana Smith
Gladstone Institutes

Public Release: 28-Sep-2014
Human genome was shaped by an evolutionary arms race with itself
New findings by scientists at the University of California, Santa Cruz, suggest that an evolutionary arms race between rival elements within the genomes of primates drove the evolution of complex regulatory networks that orchestrate the activity of genes in every cell of our bodies. The arms race is between mobile DNA sequences known as 'retrotransposons' (a.k.a. 'jumping genes') and the genes that have evolved to control them.
California Institute for Regenerative Medicine, National Institutes of Health, Howard Hughes Medical Institute

Contact: Tim Stephens
University of California - Santa Cruz

Public Release: 28-Sep-2014
Nature Medicine
Researchers identify early sign of pancreatic cancer
Scientists at Dana-Farber Cancer Institute, the Massachusetts Institute of Technology, and other institutions have discovered a sign of the early development of pancreatic cancer -- an upsurge in certain amino acids that occurs before the disease is diagnosed and symptoms appear. The research is being published online today by the journal Nature Medicine.
The Howard Hughes Medical Institute, Lustgarten Foundation, National Institutes of Health, Nestle Research Center, Robert T. and Judith B. Hale Fund for Pancreatic Cancer, Perry S. Levy Fund

Contact: Anne Doerr
Dana-Farber Cancer Institute

Public Release: 27-Sep-2014
Evolutionary biology: It's not just for textbooks anymore
UA scientists, including entomology expert Bruce Tabashnik, are on the leading edge of an approach to tackle global challenges in food security, emerging diseases and biodiversity loss.
National Science Foundation, NIH/National Institute of General Medical Sciences, Maine Agricultural and Forest Experiment Station, National Research Centre for Growth and Development, Commonwealth Scientific and Industrial Research Organisation, others

Contact: Daniel Stolte
University of Arizona

Public Release: 27-Sep-2014
ESMO 2014 Congress
New England Journal of Medicine
Crizotinib treatment effective against ROS1-positive lung cancer
Treatment with the targeted therapy drug crizotinib effectively halted the growth of lung tumors driven by rearrangements of the ROS1 gene in a small clinical trial.
Pfizer, NIH/National Cancer Institute, Uniting Against Lung Cancer, Swedish Research Council, Be a Piece of the Solution

Contact: Katie Marquedant
Massachusetts General Hospital

Public Release: 26-Sep-2014
Global Society
Disease without borders
In a paper published this week online in Global Society, researchers with University of California, San Diego School of Medicine and the Urban Studies and Planning Program, also at UC San Diego, present a bioregional guide that merges place-based (territorial) city planning and ecosystem management along the United States-Mexico border as way to improve human and environmental health.
NIH/National Institute of Environmental Health Sciences

Contact: Yadira Galindo
University of California - San Diego

Public Release: 26-Sep-2014
Geisel researchers contribute to study of trained immunity
A study published in the journal Science provides support for a new -- and still controversial -- understanding of the immune system. The research was conducted by collaborators in the US and Europe, including Robert Cramer, Ph.D., an assistant professor of microbiology and immunology at Dartmouth's Geisel School of Medicine.
NIH/National Institute of General Medical Sciences, NIH/National Institute of Allergy and Infectious Diseases

Contact: Derik Hertel
The Geisel School of Medicine at Dartmouth

Public Release: 26-Sep-2014
Policies of NIH, other funders, have improved data-sharing by life-science investigators
Policies put into place by major funding agencies like the National Institutes of Health, and to a lesser extent by scientific journals, appear to be meeting the goal of increasing the sharing of scientific resources among life science investigators.
NIH/National Human Genome Research Institute

Contact: Terri Ogan
Massachusetts General Hospital

Public Release: 25-Sep-2014
With NIH grant, Cedars-Sinai helps bring big data to neuro disease research
Investigators at the Cedars-Sinai Board of Governors Regenerative Medicine Institute have received a grant from the National Institutes of Health to participate in a consortium taking the study of motor neuron disorders -- such as Lou Gehrig's disease and spinal muscular atrophy -- to a new, comprehensive perspective.
National Institutes of Health

Contact: Sandy Van
Cedars-Sinai Medical Center

Public Release: 25-Sep-2014
After watching disturbing video, CPAP usage soars
It's estimated that more than 20 million Americans have sleep apnea, and if you're one of them, you may have been given a mask to wear overnight to help you breathe. They're called CPAP masks, and even though they can be extremely effective, more than half of all patients who have them don't use them. Now, doctors at National Jewish Health have found a way to change that.
National Institutes of Health

Contact: Shannon McCormick
National Jewish Health

Public Release: 25-Sep-2014
National team awarded $16 million NIH grant to study genetics of schizophrenia and bipolar disorder
A multi-institutional team of researchers studying schizophrenia and bipolar disorder has been awarded a $16 million grant from the National Institute of Mental Health to create the most extensive genetic resource to date for these two devastating psychiatric disorders, using data assembled by the University of Southern California.
NIH/National Institute of Mental Health

Contact: Alison Trinidad
University of Southern California - Health Sciences

Public Release: 25-Sep-2014
Addiction Science & Clinical Practice
BUSM researchers find NAS treatment needs standardization
When it comes to treating infants with neonatal abstinence syndrome (NAS), researchers from Boston University School of Medicine believe the care for these infants should be consistent and objective, with standardized assessment tools and evidence to back up pharmacologic and nonpharmacologic treatment choices.
NIH/National Institute on Drug Abuse

Contact: Jenny Eriksen Leary
Boston University Medical Center

Public Release: 25-Sep-2014
Researchers engineer 'Cas9' animal models to study disease and inform drug discovery
Researchers from the Broad Institute and Massachusetts Institute of Technology have created a new mouse model to simplify application of the CRISPR-Cas9 system for in vivo genome editing experiments. The researchers successfully used the new 'Cas9 mouse' model to edit multiple genes in a variety of cell types, and to model lung adenocarcinoma, one of the most lethal human cancers. A paper describing this new model and its initial applications appears this week in Cell.
National Science Foundation, The Damon Runyon Cancer Research Institute, MIT/Simons Center for the Social Brain, NIH/National Human Genome Research Institute, NIH/National Cancer Institute, NIH/National Institute of Mental Health

Contact: Haley Bridger
Broad Institute of MIT and Harvard

Public Release: 25-Sep-2014
Cancer Cell
USC researchers discover dual purpose of cancer drug in regulating expression of genes
Keck Medicine of USC scientists have discovered new clues about a drug instrumental in treating a certain blood cancer that may provide important targets for researchers searching for cures.
National Institutes of Health

Contact: Leslie Ridgeway
University of Southern California - Health Sciences

Public Release: 25-Sep-2014
Clinical Gastroenterology and Hepatology
Risk of esophageal cancer decreases with height
Taller individuals are less likely to develop esophageal cancer and it's precursor, Barrett's esophagus, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.
National Institutes of Health

Contact: Rachel Steigerwald
American Gastroenterological Association

Showing releases 3451-3475 out of 3755.

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