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Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 3451-3475 out of 3603.

<< < 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 | 142 | 143 > >>

Public Release: 13-Mar-2014
American Journal of Medicine
Older adults: Build muscle and you'll live longer
New research suggests that the more muscle mass older Americans have, the less likely they are to die prematurely. The findings add to the growing evidence that overall body composition -- and not the widely used body mass index, or BMI -- is a better predictor of all-cause mortality.
NIH/National Institute on Aging

Contact: Enrique Rivero
University of California - Los Angeles Health Sciences

Public Release: 13-Mar-2014
American Journal of Public Health
Negative effects of joining a gang last long after gang membership ends
Joining a gang in adolescence has significant consequences in adulthood beyond criminal behavior, even after a person leaves the gang. Former gang members are more likely to be in poor health, receiving government assistance and struggling with drug abuse than someone who never joined a gang.
NIH/National Institute on Drug Abuse, NIH/National Institute on Mental Health, Robert Wood Johnson Foundatio

Contact: Amanda Gilman
University of Washington

Public Release: 13-Mar-2014
Bioscientists develop 'grammar' to design useful synthetic living systems
Researchers at the Massachusetts Institute of Technology and Virginia Tech have used a computer-aided design tool to create genetic languages to guide the design of biological systems.
Defense Advanced Research Projects Agency, National Institutes of Health, National Science Foundation, Office of Naval Research

Contact: Tiffany Trent
Virginia Tech

Public Release: 13-Mar-2014
New stroke research combines brain stimulation, gait training
A University of Illinois at Chicago researcher will test whether brain stimulation combined with gait training can improve patients' ability to walk after a stroke, under a $1.5 million grant from the National Institute of Child Health and Human Development.
NIH/National Institute of Child Health and Human Development

Contact: Jeanne Galatzer-Levy
University of Illinois at Chicago

Public Release: 13-Mar-2014
Journal of Marriage and Family
Husband's health and attitude loom large for happy long-term marriages
A husband's agreeable personality and good health appear crucial to preventing conflict among older couples who have been together a long time, according to a study from University of Chicago researchers.
NIH/National Institute on Aging

Contact: Jann Ingmire
University of Chicago

Public Release: 13-Mar-2014
Plant biology discovery furthers scientists' understanding of plant growth and development
UC Riverside plant cell biologists have discovered an 'auxin sensing and signaling complex' localized on the plant cell surface. Discovered by Charles Darwin, auxin is a plant hormone that controls nearly every aspect of plant growth and development. About a decade ago, an auxin sensing and signaling system had been discovered in the cell's nucleus; but it could not explain auxin's diverse roles. The new discovery provides new insights into the mode of auxin action.
NIH/National Institute of General Medical Sciences

Contact: Iqbal Pittalwala
University of California - Riverside

Public Release: 13-Mar-2014
Cell Reports
A gene family that suppresses prostate cancer
Cornell University researchers report they have discovered direct genetic evidence that a family of genes, called microRNA-34, are bona fide tumor suppressors.
National Institutes of Health, New York State Stem Cell Science, Deutsche Krebshilfe

Contact: Joe Schwartz
Cornell University

Public Release: 13-Mar-2014
These boosts are made for walkin'
New research by UC San Francisco neuroscientists suggests that the body may get help in fast-changing situations from a specialized brain circuit that causes visual system neurons to fire more strongly during locomotion.
National Institutes of Health

Contact: Peter Farley
University of California - San Francisco

Public Release: 13-Mar-2014
One in 5 older Americans take medications that work against each other
About three out of four older Americans have multiple chronic health conditions, and more than 20 percent of them are being treated with drugs that work at odds with each other -- the medication being used for one condition can actually make the other condition worse.
National Institutes of Health

Contact: David Lee
Oregon State University

Public Release: 13-Mar-2014
Frontiers in Oncology
Study proposes new ovarian cancer targets
Proteins called TAFs were once thought to be generic cogs in the machinery of gene expression, but in a new study Brown University scientists propose that they may be important suspects in the progression of ovarian cancer that should not continue to be overlooked.
National Institutes of Health, American Cancer Society, Canadian Institutes of Health

Contact: David Orenstein
Brown University

Public Release: 13-Mar-2014
Research findings link post-heart attack biological events that provide cardioprotection
Heart attack and stroke are among the most serious threats to health. But novel research at UT Southwestern Medical Center has linked two major biological processes that occur at the onset of these traumatic events and, ultimately, can lead to protection for the heart.
National Institutes of Health, CPRIT, American Heart Association/DeHaan Foundation, Fondation Leducq

Contact: Lisa Warshaw
UT Southwestern Medical Center

Public Release: 13-Mar-2014
Arteriosclerosis, Thrombosis, and Vascular Biology
Novel marker and possible therapeutic target for cardiovascular calcification identified
Led by Dr. Aikawa, a team of researchers at BWH and Kowa Company, Ltd., a Japanese pharmaceutical company, has discovered certain proteins in osteoclasts, a precursor to bone, that may be used in helping to destroy cardiovascular calcification by dissolving mineral deposits. The research, described in the March 2014 issue of Arteriosclerosis, Thrombosis, and Vascular Biology, suggests a potential therapeutic avenue for patients with cardiovascular calcification.
Kowa Company, Ltd., National Institutes of Health

Contact: Lori J Schroth
Brigham and Women's Hospital

Public Release: 13-Mar-2014
Journal of Cell Biology
'Velcro protein' found to play surprising role in cell migration
Studying epithelial cells, the cell type that most commonly turns cancerous, Johns Hopkins researchers have identified a protein that causes cells to release from their neighbors and migrate away from healthy mammary, or breast, tissue in mice. They also found that deletion of a cellular 'Velcro protein' does not cause the single-celled migration expected. Their results, they say, help clarify the molecular changes required for cancer cells to metastasize.
American Cancer Society, NIH/National Cancer Institute, NIH/National Institute of General Medical Sciences, NIH/National Center for Research Resources, Safeway, Avon, Hay Graduate Award, Kleberg Foundation

Contact: Catherine Kolf
Johns Hopkins Medicine

Public Release: 13-Mar-2014
Deficient protein GM-CSF production found to impair gut's immune tolerance
Deletion of the GM-CSF gene in mice was shown to reduce and impair regulatory function of the gut tissue macrophages and dendritic cells, which compromised oral tolerance and increased susceptibility to inflammatory bowel disease.
National Institutes of Health, German Research Foundation

Contact: Sid Dinsay
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 13-Mar-2014
Unraveling a mystery in the 'histone code' shows how gene activity is inherited
Every cell in our body has exactly the same DNA, yet every cell is different. The genetic code carried in our DNA provides instructions for cells to manufacture specific proteins. A second code, carried by histone proteins bound to DNA, determines which genes are activated in particular cells. Researchers at CSHL have found that the slightest variation in a histone protein can have dramatic effects on how the genes encoded in our DNA are used.
Howard Hughes Medical Institute, National Science Foundation, National Institutes of Health

Contact: Jaclyn Jansen
Cold Spring Harbor Laboratory

Public Release: 13-Mar-2014
American Journal of Public Health
Falls among elderly reduced by state program
A low-cost program reduced falls in the elderly by 17 percent statewide, illustrating the value and effectiveness of using existing aging services, such as senior centers, in preventing falls, a University of Pittsburgh Graduate School of Public Health study determined. Pitt Public Health researchers followed nearly 2,000 older Pennsylvanians between 2010 and 2011 to determine the effectiveness of the state's Healthy Steps for Older Adults, a voluntary fall-prevention program.
Centers for Disease Control, National Institutes of Health

Contact: Allison Hydzik
University of Pittsburgh Schools of the Health Sciences

Public Release: 13-Mar-2014
New view of tumors' evolution
MIT researchers find that the sequencing of cancer cell genomes reveals potential new drug targets for an aggressive type of lung cancer.
Massachusetts Institute of Technology/Ludwig Center for Molecular Oncology, Howard Hughes Medical Institute, NIH/National Human Genome Research Institute, NIH/National Cancer Institute, Hope Funds for Cancer Research

Contact: Sarah McDonnell
Massachusetts Institute of Technology

Public Release: 13-Mar-2014
Researchers identify gene that helps fruit flies go to sleep
In a series of experiments sparked by fruit flies that couldn't sleep, Johns Hopkins researchers say they have identified a mutant gene -- dubbed 'Wide Awake' -- that sabotages how the biological clock sets the timing for sleep. The finding also led them to the protein made by a normal copy of the gene that promotes sleep early in the night and properly regulates sleep cycles.
NIH/National Institute of General Medical Sciences

Contact: Stephanie Desmon
Johns Hopkins Medicine

Public Release: 13-Mar-2014
Columbia researchers discover reversible mechanism that increases muscle elasticity
Columbia University biological sciences professor Julio Fernandez and team report the discovery of a new form of mechanical memory that adjusts the elasticity of muscles to their history of stretching. Using highly sensitive atomic force microscopes, the researchers detected a chemical reaction that increases the elasticity of muscle proteins. Crucially, this reaction targets molecules that have been exposed to a stretching force. This finding changes our understanding of how muscles respond to stretching and may lead to new treatments of muscle disorders.
National Institutes of Health

Contact: Beth Kwon
Columbia University

Public Release: 13-Mar-2014
American Journal of Human Genetics
Penn team links Africans' ability to digest milk to spread of cattle raising
A new study led by University of Pennsylvania researchers -- constituting the largest investigation ever of lactose tolerance in geographically diverse populations of Africans -- investigated the genetic origins of this trait and offers support to the idea that the ability to digest milk was a powerful selective force in a variety of African populations which raised cattle and consumed the animals' fresh milk.
National Science Foundation, National Institutes of Health

Contact: Katherine Unger Baillie
University of Pennsylvania

Public Release: 13-Mar-2014
Stroke: Journal of the American Heart Association
Mexican-Americans suffer worse outcomes after stroke
Mexican-Americans had worse neurologic, functional and cognitive outcomes 90 days after their stroke compared to non-Hispanic whites. Mexican-American stroke survivors had moderate functional disability and nearly one-third had post-stroke dementia.
National Institutes of Health

Contact: Karen Astle
American Heart Association

Public Release: 13-Mar-2014
Cancer Discovery
Bladder cancer Pt with rare genetic mutations shows exceptional response to everolimus
A patient with advanced bladder cancer experienced a complete response for 14 months to the drug combination everolimus and pazopanib in a phase I trial, and genomic profiling of his tumor revealed two alterations that may have caused this exceptional response, according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research.
Next Generation Fund, NIH/National Human Genome Research Institute, GSK, Novartis

Contact: Jeremy Moore
American Association for Cancer Research

Public Release: 13-Mar-2014
PLOS Computational Biology
Autism and intellectual disability incidence linked with environmental factors
An analysis of 100 million US medical records reveals that autism and intellectual disability rates correlate with genital malformation incidence in newborn males, an indicator of congenital exposure to harmful environmental factors such as pesticides. Autism rates jump by 283 percent for every one percent increase in frequency of malformations in a county. In addition, the study finds that Autism and ID incidence decrease by roughly 99 percent in states with stronger regulations on diagnosis.
NIH/National Institute for Mental Health

Contact: Kevin Jiang
University of Chicago Medical Center

Public Release: 13-Mar-2014
Scripps Research Institute scientists discover a better way to make unnatural amino acids
Chemists at the Scripps Research Institute have devised a greatly improved technique for making amino acids not found in nature. These 'unnatural' amino acids traditionally have been very difficult to synthesize but are sought after by the pharmaceutical industry for their potential medical uses.
NIH/National Institute of General Medical Sciences, Bristol-Myers Squibb

Contact: Mika Ono
Scripps Research Institute

Public Release: 13-Mar-2014
Cell Reports
Mount Sinai scientists discover how Marburg virus grows in cells
Marburg virus leads to death in approximately 90 percent of cases and no treatments are yet available. This cell culture study provides important molecular details. These findings could prove useful in developing inhibitors for the virus.
National Institutes of Health, US Department of Defense

Contact: Sid Dinsay
The Mount Sinai Hospital / Mount Sinai School of Medicine

Showing releases 3451-3475 out of 3603.

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