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Public Release: 10-Jul-2009

Journal of Clinical Investigation
New role discovered for molecule important in development of the pancreas
For years researchers have been searching for a way to treat diabetics by reactivating their insulin-producing beta cells, to no avail. Now, they may be one step closer. A protein, whose role in pancreatic development has long been recognized, has been discovered to play an additional and previously unknown regulatory role in the development of cells in the immature endocrine system. These cells ultimately give rise to pancreatic islet cells, which include beta cells.

NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Public Release: 10-Jul-2009

Journal of Biological Inorganic Chemistry
New oral agents may prevent injury after radiation exposure
Researchers from Boston University School of Medicine and collaborators have discovered and analyzed several new compounds, collectively called the ''EUK-400 series,'' which could someday be used to prevent radiation-induced injuries to kidneys, lungs, skin, intestinal tract and brains of radiological terrorism victims.

NIH/National Institute of Allergy and Infectious Diseases

Public Release: 9-Jul-2009

Angewandte Chemie
Caltech chemists say antibody surrogates are just a 'click' away
Chemists at the California Institute of Technology and the Scripps Research Institute have developed an innovative technique to create cheap but highly stable chemicals that have the potential to take the place of the antibodies used in many standard medical diagnostic tests.

NIH/National Cancer Institute, MITRE Corporation

Public Release: 9-Jul-2009

Biochimica et Biophysica Acta
Systems biology recommended as a clinical approach to cancer
Researchers at the Virginia Bioinformatics Institute at Virginia Tech and the Wake Forest University School of Medicine are advocating the use of systems biology as an innovative clinical approach to cancer. This approach could result in the development of improved diagnostic tools and treatment options, as well as potential new drug targets to help combat the many potentially fatal types of the disease.

NIH/National Cancer Institute, Biotechnology and Biological Sciences Research Council, Engineering and Physical Sciences Research Council

Public Release: 9-Jul-2009

Cancer Epidemiology, Biomarkers and Prevention
Link between migraines and reduced breast cancer risk confirmed in follow-up study
The relationship between migraine headaches in women and a significant reduction in breast cancer risk has been confirmed in a follow-on study to landmark research published last year and conducted by scientists at Fred Hutchinson Cancer Research Center. The new study found a 26 percent reduced risk of breast cancer among both premenopausal and postmenopausal women with a clinical diagnosis of migraines.

NIH/National Institute of Child Health and Human Development

Public Release: 8-Jul-2009
Map of your brain may reveal early mental illness
Northwestern University researchers are producing topographical maps of people's healthy and schizophrenic brains in an effort to develop the first scientific tool for early and more definite diagnosis of mental disorders such as schizophrenia. The scientists have already found differences in the hippocampus in people who have schizophrenia. Diagnosing the beginning stage of mental disorders remains elusive, although this when they are most treatable.

NIH/National Institutes of Mental Health