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Department of Health and Human Services

News from the National Institutes of Health

Funded News


Key: Meeting M      Journal J      Funder F

Showing releases 51-75 out of 3753.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 > >>

Public Release: 29-Jun-2015
Molecular Oncology
Mayo Clinic study suggests which glioblastoma patients may benefit from drug treatment
Clinicians testing the drug dasatinib, approved for several blood cancers, had hoped it would slow the aggressive growth of the deadly brain cancer glioblastoma; however, clinical trials to date have not found any benefit. Researchers at Mayo Clinic, who conducted one of those clinical trials, believe they know why dasatinib failed -- and what to do about it.
National Institutes of Health

Contact: Kevin Punsky
punsky.kevin@mayo.edu
904-953-0746
Mayo Clinic

Public Release: 29-Jun-2015
PLOS Pathogens
TSRI and biotech partners find new antibody weapons against Marburg virus
A new study led by scientists at the Scripps Research Institute identifies new immune molecules that protect against deadly Marburg virus, a relative of Ebola virus. The research provides ingredients needed to develop treatments for future Marburg outbreaks.
NIH/National Institute of Allergy and Infectious Diseases, National Science Foundation, Japan Society for Promotion of Science, Uehara Memorial Foundation, Investigators in the Pathogenesis of Infectious Disease etc.

Contact: Madeline McCurry-Schmidt
madms@scripps.edu
858-784-9254
Scripps Research Institute

Public Release: 29-Jun-2015
Researchers complete ASPIRE Phase III trial of vaginal ring for HIV prevention in women
In a first for HIV prevention, researchers have completed follow-up of participants in a pivotal Phase III trial that tested a vaginal ring for preventing HIV in women. The ring, which contains the ARV dapivirine, is meant to be worn for a month at a time. More than 2,600 African women took part in ASPIRE, one of two Phase III trials designed to support potential licensure of the ring. Results are expected early 2016.
NIH/National Institute of Allergy and Infectious Diseases, NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH/National Institute of Mental Health

Contact: Lisa Rossi
rossil@upmc.edu
412-916-3315
Microbicide Trials Network

Public Release: 29-Jun-2015
Proceedings of the National Academy of Sciences
Researchers discover how petunias know when to smell good
A team of UW biologists has identified a key mechanism plants use to decide when to release their floral scents to attract pollinators. Their findings, published the week of June 29 in the Proceedings of the National Academy of Sciences, connect the production and release of these fragrant chemicals to the innate circadian rhythms that pulse through all life on Earth.
National Institutes of Health, National Science Foundation

Contact: James Urton
jurton@uw.edu
206-543-2580
University of Washington

Public Release: 29-Jun-2015
Proceedings of the National Academy of Sciences
Treatment with PI3K inhibitors may cause cancers to become more aggressive and metastatic
The enzyme PI3K appears to be exploited in almost every type of human cancer, making it the focus of considerable interest as a therapeutic target. However, PI3K inhibitors have only shown modest clinical activity. Now, new research from The Wistar Institute shows that treatment with PI3K inhibitors alone may actually make a patient's cancer even worse by promoting more aggressive tumor cell behavior and increasing the cancer's potential of spreading to other organs.
National Institutes of Health, Prostate Cancer Research Program, Joint Grant in Molecular Medicine from Fondazione IRCCS Ca' Granda, Instituto Nazionale Genetica Molecolare

Contact: Ben Leach
bleach@wistar.org
215-495-6800
The Wistar Institute

Public Release: 29-Jun-2015
Circulation
Sugary drinks linked to high death tolls worldwide
Consumption of sugary drinks may lead to an estimated 184,000 adult deaths each year worldwide, according to research published today in the journal Circulation and previously presented as an abstract at the American Heart Association Council on Epidemiology and Prevention in 2013.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, NIH/National Heart, Lung and Blood Institute, Bill & Melinda Gates Foundation

Contact: Andrea Grossman
617-636-3728
Tufts University, Health Sciences Campus

Public Release: 29-Jun-2015
Human Molecular Genetics
Genes leave some kids prone to weakness in wrist bones
Pediatric researchers have discovered gene locations affecting bone strength in wrist bones, the most common site for fractures in children. Children who have those genetic variants may be at higher-than-average risk of wrist fractures, and could especially benefit from activities and diets that promote bone strength.
National Institutes of Health

Contact: Joey McCool Ryan
McCool@email.chop.edu
267-426-6070
Children's Hospital of Philadelphia

Public Release: 29-Jun-2015
Annals of Internal Medicine
Public health surveillance system may underestimate cases of acute hepatitis C infection
A new study suggests massive under reporting may occur within the system set up by the US Centers for Disease Control and Prevention to estimate the incidence of acute hepatitis C virus infection. A research team found that less than 1 percent of a group of acute HCV patients in Massachusetts had been reported to the CDC, largely because required data was either not available or did not meet CDC definitions for acute HCV infection.
National Institutes of Health, Centers for Disease Control and Prevention

Contact: McKenzie Ridings
mridings@partners.org
617-726-0274
Massachusetts General Hospital

Public Release: 29-Jun-2015
Nature Neuroscience
His and her pain circuitry in the spinal cord
New research released today in Nature Neuroscience reveals for the first time that pain is processed in male and female mice using different cells. These findings have far-reaching implications for our basic understanding of pain, how we develop the next generation of medications for chronic pain -- which is by far the most prevalent human health condition -- and the way we execute basic biomedical research using mice.
Canadian Institutes of Health Research, Louise and Alan Edwards Foundation, National Institutes of Health, SickKids Foundation

Contact: Chris Chipello
christopher.chipello@mcgill.ca
514-398-4201
McGill University

Public Release: 29-Jun-2015
Nature Genetics
Pinpointing mutations in a relapsed children's cancer may lead to improved treatments
Researchers studying the pediatric cancer neuroblastoma have detailed how cancer-driving mutations evolve during chemotherapy, and they hope to exploit this knowledge to design better treatments for children.
National Institutes of Health, University of Pennsylvania Genome Frontiers Institute

Contact: Ashley Moore
MooreA1@email.chop.edu
267-426-6071
Children's Hospital of Philadelphia

Public Release: 29-Jun-2015
Circulation
PTSD raises odds of heart attack and stroke in women
Women with elevated symptoms of post-traumatic stress disorder consistent with the clinical threshold for the disorder had 60 percent higher rates of having a heart attack or stroke compared with women who never experienced trauma, according to scientists at Columbia University's Mailman School of Public Health and the Harvard T.H. Chan School of Public Health. Results appear in Circulation, the journal of the American Heart Association.
National Institutes of Health

Contact: Tim Paul
tp2111@columbia.edu
212-305-2676
Columbia University's Mailman School of Public Health

Public Release: 29-Jun-2015
Circulation: Journal of the American Heart Association
PTSD, traumatic experiences may raise heart attack, stroke risk in women
Women with severe PTSD or traumatic events may have a 60 percent higher lifetime risk of cardiovascular disease. The study is the first to examine trauma exposure, PTSD, and onset of cardiovascular disease exclusively in women. Researchers suggest physicians ask women about traumatic events and PTSD symptoms and then monitor them for cardiovascular issues.
National Institutes of Health

Contact: Bridgette McNeill
bridgette.mcneill@heart.org
214-706-1135
American Heart Association

Public Release: 29-Jun-2015
Journal of General Physiology
A microtubule 'roadway' in the retina helps provide energy for vision
Researchers have discovered a thick band of microtubules in certain neurons in the retina that they believe acts as a transport road for mitochondria that help provide energy required for visual processing.
NIH/National Heart Lung and Blood Institute, National Institutes of Health

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press

Public Release: 29-Jun-2015
Nature Genetics
Rare gene variant associated with middle ear infections
An international consortium led by those at Baylor College of Medicine may have taken the first step on the road to understanding why only some people get frequent painful or chronic middle ear infections. The culprit may be rare genetic variants in a gene called A2ML1.
Hearing Health Foundation, Action On Hearing Loss, National Organization for Hearing Research Foundation, University of the Philippines Manila-National Institutes of Health, National Institutes of Health

Contact: Glenna Vickers
picton@bcm.edu
713-798-4710
Baylor College of Medicine

Public Release: 29-Jun-2015
Journal of Clinical Investigation
New strategies against rare, fatal lung syndrome
People with certain forms of the rare genetic disorder Hermansky-Pudlak syndrome face the specter of untreatable, progressive and ultimately fatal pulmonary fibrosis as early as their 30s or 40s. A new study in humans and mice identifies how the disease appears to work and demonstrates in mice two potential ways to affect its course.
American Thoracic Society, Hermanksy-Pudlak Syndrome Network, National Institutes of Health

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University

Public Release: 28-Jun-2015
Molecular & Cellular Proteomics
SAPH-ire helps scientists prioritize protein modification research
Researchers have developed a new informatics technology that analyzes existing data repositories of protein modifications and 3-D protein structures to help scientists identify and target research on 'hotspots' most likely to be important for biological function.
National Institutes of Health, NIH/National Institute of General Medical Sciences

Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology

Public Release: 28-Jun-2015
Lancet Global Health
More secondary schooling reduces HIV risk
Longer secondary schooling substantially reduces the risk of HIV infection -- especially for girls -- and could be a very cost-effective way to halt the spread of the virus, according to researchers from Harvard T.H. Chan School of Public Health. In a study in Botswana, researchers found that, for each additional year of secondary school, students lowered their risk of HIV infection by 8 percentage points about a decade later, from 25 percent to about 17 percent infected.
Harvard T.H. Chan School of Public Health, Belgian American Educational Foundation, Fernand Lazard Foundation, Boston University, National Institutes of Health

Contact: Marge Dwyer
mhdwyer@hsph.harvard.edu
617-432-8416
Harvard School of Public Health

Public Release: 26-Jun-2015
Stroke
Having a stroke? Where you are makes a huge difference in your treatment
It looks like a crazy quilt spread over the continent. But a new map of emergency stroke care in America shows just how much of a patchwork system we still have for delivering the most effective stroke treatment. And thousands of people a year may end up unnecessarily disabled as a result.
NIH/National Institute for Neurological Disorders and Stroke, NIH/National Institute of Minority Health and Health Disparities

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System

Public Release: 26-Jun-2015
$7 million awarded to study early influences on cognitive, physical health by midlife
University of California, Riverside psychologist Chandra A. Reynolds has been awarded a $7 million, five-year grant by the National Institute on Aging to study how early childhood influences versus recent influences affect cognitive and physical health by middle age.
NIH/National Institute on Aging

Contact: Bettye Miller
bettye.miller@ucr.edu
951-827-7847
University of California - Riverside

Public Release: 26-Jun-2015
PLOS Medicine
High blood pressure linked to reduced Alzheimer's risk, meds may be reason
A new study suggests that people with a genetic predisposition to high blood pressure have a lower risk for Alzheimer's disease. However, authors conclude the connection may have more to do with anti-hypertension medication than high blood pressure itself.
Innovative Medicines Initiative Joint Undertaking, National Institute for Health Research, Maudsley NHS Foundation Trust, National Institutes of Health, NIH/National Institute on Aging

Contact: Todd Hollingshead
toddh@byu.edu
801-422-8373
Brigham Young University

Public Release: 26-Jun-2015
Genes & Development
Braking mechanism identified for cell growth pathway linked to several cancers
Researchers at University of California, San Diego School of Medicine have discovered a self-regulating loop in the Hippo pathway, a signaling channel garnering increased attention from cancer researchers due to its role in controlling organ size, cell proliferation and cell death.
National Institutes of Health, Japan Society for the Promotion of Science, Yasuda Medical Foundation, UC San Diego

Contact: Bonnie Ward
bjward@ucsd.edu
619-543-6163
University of California - San Diego

Public Release: 25-Jun-2015
Neurobiology of Aging
Alzheimer's disease works differently in patients with and without Down syndrome
Researchers at the University of Kentucky's Sanders-Brown Center on Aging have completed a study that revealed differences in the way brain inflammation -- considered a key component of Alzheimer's disease -- is expressed in different subsets of patients, in particular people with Down syndrome and AD.
NIH/National Institute of Child Health and Human Development, Alzheimer's Association, Global Down Syndrome Foundation, Linda CRNIC Institute for Down Syndrome

Contact: Laura Dawahare
Laura.Dawahare@uky.edu
859-257-5307
University of Kentucky

Public Release: 25-Jun-2015
Stem Cell Reports
Researchers uncover epigenetic switches that turn stem cells into blood vessel cells
Researchers at the University of Illinois at Chicago have identified a molecular mechanism that directs embryonic stem cells to mature into endothelial cells -- the specialized cells that form blood vessels. Understanding the processes initiated by this mechanism could help scientists more efficiently convert stem cells into endothelial cells for use in tissue repair, or for engineering blood vessels to bypass blockages in the heart.
NIH/National Heart, Lung and Blood Institute

Contact: Sharon Parmet
sparmet@uic.edu
312-413-2695
University of Illinois at Chicago

Public Release: 25-Jun-2015
Journal of Biological Chemistry
A person's diet, acidity of urine may affect susceptibility to UTIs
The acidity of urine -- as well as the presence of small molecules related to diet -- may influence how well bacteria can grow in the urinary tract, a new study shows. The research, at Washington University School of Medicine in St. Louis, may have implications for treating urinary tract infections, which are among the most common bacterial infections worldwide.
National Institutes of Health, Longer Life Foundation, United States Public Health Service, Burroughs Wellcome Fund, Monsanto Excellence Fund Graduate Fellowship, Barnes-Jewish Hospital Patient Safety & Quality Fellowship Program

Contact: Julia Evangelou Strait
straitj@wustl.edu
314-286-0141
Washington University School of Medicine

Public Release: 25-Jun-2015
Proceedings of the Royal Society B
Tracking the genetic arms race between humans and mosquitoes
Individual populations of mosquitoes are under strong evolutionary pressure from humans and their environment, a new study shows.
National Institutes of Health, Russian Science Ministry

Contact: Robert Perkins
perkinsr@usc.edu
213-740-9226
University of Southern California

Showing releases 51-75 out of 3753.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 > >>

     
   

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