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Department of Health and Human Services

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Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 51-75 out of 3776.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 > >>

Public Release: 31-Aug-2015
Nature Methods
DNA-guided 3-D printing of human tissue is unveiled
UCSF researchers developed a technique to build tiny models of human tissues, called organoids, more precisely than ever before using a process that turns human cells into a biological equivalent of LEGO bricks. These mini-tissues in a dish can be used to study how particular structural features of tissue affect normal growth or go awry in cancer; for therapeutic drug screening and to help teach researchers how to grow whole human organs.
The Department of Defense Breast Cancer Research Program, the National Institutes of Health, the Sidney Kimmel Foundation, the UCSF Program in Breakthrough Biomedical Research

Contact: Nicholas Weiler
University of California - San Francisco

Public Release: 31-Aug-2015
Biosensors and Bioelectronics
Mouth guard monitors health markers, transmits information wirelessly to smart phone
Engineers at the University of California, San Diego, have developed a mouth guard that can monitor health markers, such as lactate, cortisol and uric acid, in saliva and transmit the information wirelessly to a smart phone, laptop or tablet. The technology, which is at a proof-of-concept stage, could be used to monitor patients continuously without invasive procedures, as well as to monitor athletes' performance or stress levels in soldiers and pilots.
National Institutes of Health, Air Force Research Laboratory

Contact: Liezel Labios
University of California - San Diego

Public Release: 31-Aug-2015
New research confirms lack of sleep connected to getting sick
In 2009, Carnegie Mellon University's Sheldon Cohen found for the first time that insufficient sleep is associated with a greater likelihood of catching a cold. To do this, Cohen assessed participants self-reported sleep duration and efficiency levels and then exposed them to a common cold virus. Now, Cohen and other researchers have confirmed that insufficient sleep is connected to an increased chance of getting sick using objective sleep measures.
NIH/National Center for Complementary and Integrative Health, NIH/National Institute of Allergy and Infectious Diseases, NIH/National Heart, Lung, and Blood Institute, National Institutes of Health

Contact: Shilo Rea
Carnegie Mellon University

Public Release: 31-Aug-2015
Psychological Science
Close friendships in adolescence predict health in adulthood
Teens are often warned to beware the undue influence of peer pressure, but new research suggests that following the pack in adolescence may have some unexpected benefits for physical health in early adulthood.
NIH/National Institute of Child Health and Human Development, NIH/National Institute of Mental Health

Contact: Anna Mikulak
Association for Psychological Science

Public Release: 31-Aug-2015
Nature Medicine
'Eat me' signal whets appetites for tumor-devouring dendritic cells
The therapeutic effect of CD47 blockade as a cancer treatment relies more on dendritic cells than macrophages. Anti-CD47-mediated tumor rejection will require both innate and adaptive responses.
National Institutes of Health, Chinese Academy of Sciences

Contact: John Easton
University of Chicago Medical Center

Public Release: 31-Aug-2015
Journal of Cell Biology
Inducing metabolic catastrophe in cancer cells
Researchers at Harvard Medical School describe a way to force cancer cells to destroy a key metabolic enzyme they need to survive.
Harvard Accelerator Fund, Ludwig Center at Harvard, Chinese Academy of Sciences, Swedish Research Council, Swedish Society for Medical Research, NIH/Bational Heart, Lung, and Blood Institute, and others

Contact: Rita Sullivan King
Rockefeller University Press

Public Release: 31-Aug-2015
American Journal of Preventive Medicine
'Happy Meals' bill could improve healthfulness of fast food meals for kids in NYC
A bill to improve the nutritional value of fast food restaurant meals marketed to children -- like McDonald's Happy Meals -- could have a wide enough impact to reduce calories, fat, and sodium, according to a new study led by researchers at NYU Langone Medical Center.
NIH/National Institute of Diabetes and Digestive and Kidney Disorders, New York State Health Foundation, Robert Wood Johnson Foundation

Contact: Allison Clair
NYU Langone Medical Center / New York University School of Medicine

Public Release: 28-Aug-2015
UC San Diego cancer researchers receive NCI Outstanding Investigator Award
Four University of California, San Diego School of Medicine researchers have been selected to receive the newly established National Cancer Institute Outstanding Investigator Award. The multi-million dollar awards fund new projects that have an unusual potential in cancer research over seven years.
NIH/National Cancer Institute

Contact: Yadira Galindo
University of California - San Diego

Public Release: 28-Aug-2015
OU and Mercy Hospital OKC developing new screening models for breast cancer detection
The University of Oklahoma and Mercy Hospital Oklahoma City are developing new short-term breast cancer risk prediction models that aim to help increase cancer detection of breast magnetic resonance imaging screening. With a $2.5 million grant from the National Institutes of Health/National Cancer Institute, OU and Mercy will develop and apply two new short-term breast cancer risk prediction approaches: a rule-in approach and a rule-out approach.
NIH/National Cancer Institute

Contact: Jana Smith
University of Oklahoma

Public Release: 28-Aug-2015
Angewandte Chemie
Researchers use DNA 'clews' to shuttle CRISPR-Cas9 gene-editing tool into cells
Researchers have for the first time created and used a nanoscale vehicle made of DNA to deliver a CRISPR-Cas9 gene-editing tool into cells in both cell culture and an animal model.
National Institutes of Health, National Science Foundation

Contact: Matt Shipman
North Carolina State University

Public Release: 28-Aug-2015
Cancer Prevention Research
Moffitt makes important steps toward developing a blood test to catch pancreatic cancer early
According to a new 'proof of principle' study published in Aug. 27 issue of Cancer Prevention Research, Moffitt Cancer Center researchers hope to improve pancreatic cancer survival rates by identifying markers in the blood that can pinpoint patients with premalignant pancreatic lesions called intraductal papillary mucinous neoplasms.
American Cancer Society, NIH/National Cancer Institute

Contact: Kim Polacek
H. Lee Moffitt Cancer Center & Research Institute

Public Release: 27-Aug-2015
JAMA Neurology
Degenerating neurons respond to gene therapy treatment for Alzheimer's disease
Degenerating neurons in patients with Alzheimer's disease measurably responded to an experimental gene therapy in which nerve growth factor was injected into their brains, report researchers at University of California, San Diego School of Medicine in the current issue of JAMA Neurology.
National Institutes of Health, Veterans Health Administration, Alzheimer's Association, Donald and Darlene Shiley Family Trusts and Ceregene, Inc.

Contact: Scott LaFee
University of California - San Diego

Public Release: 27-Aug-2015
Cell Reports
HIV particles do not cause AIDS, our own immune cells do
Scientists from the Gladstone Institutes have discovered that HIV does not cause AIDS by the virus's direct effect on the host's immune cells, but rather through the cells' lethal influence on one another. In a new Cell Reports study, the researchers revealed that the HIV 'death pathway' -- how 95 percent of cells die from the virus -- is only initiated if the virus is passed from cell-to-cell, not if cells are infected by free-floating viral particles.
National Institutes of Health, NIH/National Institute of Allergy and Infectious Diseases

Contact: Dana Smith
Gladstone Institutes

Public Release: 27-Aug-2015
Pitt team identifies cause of resilience to tinnitus, potential drug therapy
Researchers have identified in an animal model the molecular mechanisms behind resilience to noise-induced tinnitus and a possible drug therapy that could reduce susceptibility to this chronic and sometimes debilitating condition. The findings by a team from the University of Pittsburgh School of Medicine were published online in the journal eLife.
US Department of Defense Peer Reviewed Medical Research Program, Joint Warfighter Medical Research Program, National Institutes of Health

Contact: Allison Hydzik
University of Pittsburgh Schools of the Health Sciences

Public Release: 27-Aug-2015
Researchers thwart cancer cells by triggering 'virus alert'
Working with human cancer cell lines and mice, researchers at the Johns Hopkins Kimmel Cancer Center and elsewhere have found a way to trigger a type of immune system 'virus alert' that may one day boost cancer patients' response to immunotherapy drugs. An increasingly promising focus of cancer research, the drugs are designed to disarm cancer cells' ability to avoid detection and destruction by the immune system.
NIH/National Cancer Institute, Stand Up To Cancer Epigenetic Dream Team, Hodson Trust, Samuel Waxman Cancer Research Foundation, Dr. Miriam and Sheldon G. Adelson Medical Research Foundation, DOD/Teal Award, Pershing Square Sohn Cancer Research Alliance

Contact: Vanessa Wasta
Johns Hopkins Medicine

Public Release: 27-Aug-2015
Surprised? Cholinergic neurons send broadcasts enabling us to learn from the unexpected
Neuroscientists at CSHL have discovered a set of cholinergic neurons in the basal forebrain that broadcast messages throughout the cerebral cortex, rapidly informing multiple distributed subregions of any surprising rewards or punishments -- what scientists call reinforcers. It's a way we learn from the unexpected.
John Merck and McKnight Foundations, NIH/National Institute of Neurological Disorders and Stroke, Swartz Foundation, EU Seventh Framework Programme/Marie Curie International Outgoing Fellowship

Contact: Peter Tarr
Cold Spring Harbor Laboratory

Public Release: 27-Aug-2015
Modified bacteria become a multicellular circuit
Rice University scientists create a biological circuit by programming bacteria to alter gene expression in an entire population.
National Institutes of Health, Robert A. Welch Foundation, Hamill Foundation, National Science Foundation, China Scholarship Council

Contact: David Ruth
Rice University

Public Release: 27-Aug-2015
Journal of Molecular Diagnostics
CanDL database shines light on clinically important cancer gene mutations
To help molecular pathologists, laboratory directors, bioinformaticians and oncologists identify key mutations that drive tumor growth in tissues obtained during cancer clinical studies, researchers at the Ohio State University Comprehensive Cancer Center -- James Cancer Hospital and Solove Research Institute have designed an online database called the Cancer Driver Log, or CanDL.
Pelotonia, Prostate Cancer Foundation, American Cancer Society, NIH/National Human Genome Research Institute

Contact: Darrell E. Ward
Ohio State University Wexner Medical Center

Public Release: 26-Aug-2015
University of Hawai'i Cancer Center researcher receives 5-year $2.70 million grant
A five-year $2.70 million grant will allow UH Cancer Center researcher to study how gut bacteria can damage the liver and eventually promote the development of fibrosis and liver cancer.
NIH/National Cancer Institute

Contact: Nana Ohkawa
University of Hawaii Cancer Center

Public Release: 26-Aug-2015
Public Health Reports
HIV testing among older adults is declining, despite CDC recommendation
In 2006 the Centers for Disease Control and Prevention recommended that most doctors should automatically screen all their patients, including older adults, for HIV even if they don't exhibit any symptoms. New research from the UCLA Fielding School of Public Health finds that despite this recommendation, testing among older adults has largely fallen over time.
University of California Los Angeles, NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH/National Institute on Drug Abuse

Contact: Enrique Rivero
University of California - Los Angeles Health Sciences

Public Release: 26-Aug-2015
Taking a cue from nature: Turning alcohols into alkylating agents
Researchers at Princeton have developed a dual catalyst system that directly installs alkyl groups -- fragments containing singly bonded carbon and hydrogen atoms that have extremely useful properties for drug discovery -- onto compounds called heteroarenes. Published on Aug. 26 in the journal Nature, the reported transformation is the first to successfully use alcohols as reagents in the so-called alkylation reaction.
NIH/National Institute of General Medical Sciences, Merck, Amgen

Contact: Tien Nguyen
Princeton University

Public Release: 26-Aug-2015
Common 'heart attack' blood test may predict future hypertension
Analysis of blood samples from more than 5,000 people suggests that a more sensitive version of a blood test long used to verify heart muscle damage from heart attacks could also identify people on their way to developing hypertension well before the so-called silent killer shows up on a blood pressure machine.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases, NIH/National Heart, Lung, and Blood Institute

Contact: Ekaterina Pesheva
Johns Hopkins Medicine

Public Release: 26-Aug-2015
Researchers reveal how a common mutation causes neurodegenerative disease
Researchers have determined how the most common gene mutation in amyotrophic lateral sclerosis and frontotemporal dementia disrupts normal cell function, providing insight likely to advance efforts to develop targeted therapies for these brain diseases. Scientists from the University of Massachusetts Medical School and St. Jude Children's Research Hospital led the research, which appeared in the science journal Nature.
National Institutes of Health, Target ALS, Johns Hopkins University/The Packard Center for ALS Research, ALS Association, ALS Therapy Alliance and ALSAC

Contact: Jim Fessenden
University of Massachusetts Medical School

Public Release: 26-Aug-2015
Science Translational Medicine
Stiffer breast tissue in obese women promotes tumors
Women who are obese have a higher risk and a worse prognosis for breast cancer, but the reasons why remain unclear. A Cornell study published this month in Science Translational Medicine explains how obesity changes the consistency of breast tissue in ways that are similar to tumors, thereby promoting disease.
National Institutes of Health, National Science Foundation, Breast Cancer Research Foundation, Weill Cornell Medical College/Botwinick-Wolfensohn Foundation

Contact: Melissa Osgood
Cornell University

Public Release: 26-Aug-2015
Journal of Neuroscience
Self-control saps memory, study says
You're about to switch lanes on a busy road when you realize there's a car in your blind spot. You have to put a stop to your lane change -- and quickly. A new study by Duke University researchers in the Journal of Neuroscience suggests that this type of scenario makes a person less likely to remember what halted the action -- for example, the make and model of the car in the blind spot.
NIH/National Institute of Mental Health

Contact: Karl Bates
Duke University

Showing releases 51-75 out of 3776.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 > >>


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