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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 76-100 out of 3615.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 > >>

Public Release: 23-Mar-2015
Emerging Infectious Diseases
Scientists use DNA sequencing to trace the spread of drug-resistant TB
Scientists have for the first time used DNA sequencing to trace the fatal spread of multidrug-resistant tuberculosis between patients in the UK.
NIH/National Institute for Health Research

Contact: Sam Wong
Imperial College London

Public Release: 23-Mar-2015
Proceedings of the National Academy of Sciences
Promising vaccine strategy for type 1 diabetes extended to humans
A molecule that prevents type 1 diabetes in mice has provoked an immune response in human cells, according to researchers at National Jewish Health and the University of Colorado. The findings suggest that a mutated insulin fragment could be used to prevent type 1 diabetes in humans.
National Institutes of Health, Juvenile Diabetes Research Foundation, Children's Diabetes Foundation, Brehm Coalition

Contact: William Allstetter
National Jewish Health

Public Release: 23-Mar-2015
JAMA Internal Medicine
Discontinuing statins for patients with life limiting illness
Discontinuing statin use in patients with late-stage cancer and other terminal illnesses may help improve patients' quality of life without causing other adverse health effects, according to a new study by led by researchers at the University of Colorado Anschutz Medical Campus and Duke University and funded by the National Institute of Nursing Research.
NIH/National Institute of Nursing Research

Contact: Mark Couch
University of Colorado Denver

Public Release: 23-Mar-2015
Journal of Clinical Investigation
Metabolic compensation underlies drug resistance in glioblastoma
A new study in the Journal of Clinical Investigation indicates that mTOR inhibitor resistance in gliobalstoma is likely the result of compensatory glutamine metabolism.
Takeda Science Foundation, Ludwig Institute for Cancer Research, NIH/National Institute for Neurological Diseases and Stroke, NIH/National Cancer Institute, Ben and Catherine Ivy Foundation, Defeat GBM Research Collaboration

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 23-Mar-2015
JAMA Pediatrics
Chef-enhanced school meals increase healthy food consumption
Schools collaborating with a professionally trained chef to improve the taste of healthy meals significantly increased students' fruit and vegetable consumption, according to a new study led by researchers from Harvard T.H. Chan School of Public Health.
Project Bread, Arbella Insurance Foundation, NIH/National Cancer Institute

Contact: Todd Datz
Harvard School of Public Health

Public Release: 23-Mar-2015
Proceedings of the National Academy of Sciences
Researchers discover why drug for severe COPD becomes less effective
Roflumilast, a drug recently approved in the United States to treat severe chronic obstructive pulmonary disease (COPD), increases the production of a protein that causes inflammation, which possibly results in patients developing a tolerance to the drug after repeated use and makes the drug less effective, according to researchers at Georgia State University, Kumamoto University and the University of Rochester Medical Center.
National Institutes of Health

Contact: LaTina Emerson
Georgia State University

Public Release: 23-Mar-2015
Proceedings of the National Academy of Sciences
New gene influences apple or pear shape, risk of future disease
It's known that people who carry a lot of weight around their bellies are more likely to develop diabetes and heart disease than those who have bigger hips and thighs. But what hasn't been clear is how fat accumulates in different places to produce these classic 'apple' and 'pear' shapes. Now, researchers have discovered that a gene called Plexin D1 in zebrafish controls both where fat is stored and how fat cells are shaped.
National Institutes of Health, UNC UCRF Pilot Research Project Award, Pew Scholars in Biomedical Sciences Award, American Heart Association

Contact: Karl Bates
Duke University

Public Release: 20-Mar-2015
Letting go of the (genetic) apron strings
A new study from Princeton University sheds light on the handing over of genetic control from mother to offspring early in development. Learning how organisms manage this transition could help researchers understand larger questions about how embryos regulate cell division and differentiation into new types of cells.
NIH/National Institute of Child Health and Human Development

Contact: Catherine Zandonella
Princeton University

Public Release: 20-Mar-2015
Obesity Reviews
From soda bans to bike lanes: Which 'natural experiments' really reduce obesity?
Many public health researchers take advantage of 'natural experiments' -- comparing people's calorie consumption or physical activity levels, either before and after a policy or environmental change, or in contrast to a similar group of people not affected by that change. But not all natural experiments are created equal. A Drexel public health team has now systematically reviewed the state of the science.
NIH/National Heart, Lung and Blood Institute

Contact: Rachel Ewing
Drexel University

Public Release: 20-Mar-2015
Squid enrich their DNA 'blueprint' through prolific RNA editing
RNA editing of genomic information was thought to be sparingly used, based on a limited number of studies in mammals and flies. But recently, MBL Whitman Investigator Joshua Rosenthal and colleagues discovered the most prolific usage yet of RNA editing in the common squid, Doryteuthis pealeii, a behaviorally sophisticated marine organism that has long been prized for studies of the nervous system.
European Research Council, Israel Science Foundation, National Institutes of Health, National Science Foundation, Marine Biological Laboratory, and others

Contact: Diana Kenney
Marine Biological Laboratory

Public Release: 20-Mar-2015
Science Translational Medicine
National team led by Tufts CTSI finds navigators are integral to clinical research process
A study reported in this week's Science Translational Medicine found that qualified investigators are more likely to respond to opportunities for clinical trials if they are contacted by an institution-specific point person, or navigator.
NIH/National Center for Advancing Translational Sciences

Contact: Amy West
Tufts Clinical and Translational Science Institute

Public Release: 20-Mar-2015
Lancet Oncology
Measuring treatment response proves to be a powerful tool for guiding leukemia treatment
Measuring the concentration of leukemia cells in patient bone marrow during the first 46 days of chemotherapy should help boost survival of young leukemia patients by better matching patients with the right intensity of chemotherapy. St. Jude Children's Research Hospital investigators led the research, which appears in the March 20 edition of the journal Lancet Oncology.
National Institutes of Health, ALSAC

Contact: Summer Freeman
St. Jude Children's Research Hospital

Public Release: 20-Mar-2015
Journal of Palliative Medicine
Less futile end-of-life care observed where palliative care knowledge is greater
The greater a director of nursing's knowledge of palliative care the lower the likelihood that nursing home patients will experience futile, aggressive end-of-life care, according to a new large national study. The association was evident whether or not hospice care was available.
NIH/National Institute on Aging

Contact: David Orenstein
Brown University

Public Release: 20-Mar-2015
Penn Medicine: Potential new drug target may protect against certain neurodegenerative diseases
Penn Medicine researchers have discovered that hypermethylation -- the epigenetic ability to turn down or turn off a bad gene implicated in 10 to 30 percent of patients with amyotrophic lateral sclerosis and frontotemporal degeneration -- serves as a protective barrier inhibiting the development of these diseases. Their work, published this month in Neurology, may suggest a neuroprotective target for drug discovery efforts.
National Institutes of Health, Wyncote Foundation, Doris Duke Charitable Foundation

Contact: Lee-Ann Donegan
University of Pennsylvania School of Medicine

Public Release: 19-Mar-2015
American Journal of Public Health
Thinking of drinking and driving? What if your car won't let you?
If every new car had a built-in blood alcohol level tester that prevented impaired drivers from driving the vehicle, the US could avoid 85 percent of crash deaths attributable to alcohol-involved motor vehicle crashes. In just 15 years, that would mean preventing more than 59,000 deaths.
NIH/National Institute on Alcohol Abuse and Alcoholism, Centers for Disease Control and Prevention, University of Michigan Injury Center

Contact: Mary Beth Reilly
University of Michigan Health System

Public Release: 19-Mar-2015
American Journal of Public Health
Suspension leads to more pot use among teens, study finds
The study found that students attending schools with suspension policies for illicit drug use were 1.6 times more likely than their peers at schools without such policies to use marijuana in the next year -- and that was the case with the student body as a whole, not just those who were suspended. By contrast, those attending schools with policies of sending marijuana users to a school counselor were 50 percent less likely to use the drug.
NIH/National Institute on Drug Abuse, Australian National Health and Medical Research Council, Victorian Government's Operational Infrastructure Support Program

Contact: Deborah Bach
University of Washington

Public Release: 19-Mar-2015
Johns Hopkins researchers identify 'missing culprit' in heart failure
Working with lab animals and human heart cells, scientists from Johns Hopkins and other institutions have identified what they describe as 'the long-sought culprit' in the mystery behind a cell-signaling breakdown that triggers heart failure.
National Institutes of Health, Foundation Leducq TransAtlantic Network of Excellence, Peter Belfer Laboratory Foundation, Abraham and Virginia Weiss Professorship in Cardiology, American Heart Association, Austrian Academy of Sciences

Contact: Ekaterina Pesheva
Johns Hopkins Medicine

Public Release: 19-Mar-2015
Nature Communications
Scientists trace genomic evolution of high-risk leukemia
By genomic sequencing of leukemia cells from relapsed patients at different stages, scientists have discovered key details of how acute lymphoblastic leukemia cells mutate to survive chemotherapy.
Pediatric Cancer Genome Project, NIH/National Cancer Institute, St. Baldrick's Foundation, ALSAC

Contact: Summer Freeman
St. Jude Children's Research Hospital

Public Release: 19-Mar-2015
Magnetic Resonance Imaging
Total body iron balance: Liver MRI better than biopsy
Investigators at the Saban Research Institute of Children's Hospital Los Angeles have demonstrated that MR imaging of the liver is more accurate than liver biopsy in determining total body iron balance in patients with sickle cell disease and other disorders requiring blood transfusion therapy. This discovery follows the researchers earlier work in pioneering techniques to use MRI to noninvasively measure liver iron.
National Institutes of Health, Shire Pharmaceuticals

Contact: Ellin Kavanagh
Children's Hospital Los Angeles

Public Release: 19-Mar-2015
Current Biology
Altering brain chemistry makes us more sensitive to inequality
What if there were a pill that made you more compassionate? A new study finds that giving a drug that changes the neurochemical balance in the brain causes a greater willingness to engage in prosocial behaviors, such as ensuring that resources are divided more equally.
Institute for Molecular Neuroscience, National Institutes of Health, and Hellman Family Faculty Fund

Contact: Tom Levy
University of California - Berkeley

Public Release: 19-Mar-2015
Cell Reports
Vitamin D prevents diabetes and clogged arteries in mice
Vitamin D deficiency is linked to type 2 diabetes and heart disease, and both disorders are rooted in chronic inflammation. Now, studying mice that lack the ability to process vitamin D in immune cells involved in inflammation, Washington University researchers found that the animals made excess glucose, became resistant to insulin action and accumulated plaques in their blood vessels. He said the way those key immune cells behave without vitamin D may provide new targets for treating diabetes and atherosclerosis patients.
NIH/National Heart, Lung and Blood Institute, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Children's Discovery Institute, American Diabetes Association

Contact: Jim Dryden
Washington University School of Medicine

Public Release: 19-Mar-2015
Alzheimer's & Dementia
New MIND diet may significantly protect against Alzheimer's disease
A new diet, appropriately known by the acronym MIND, could significantly lower a person's risk of developing Alzheimer's disease, even if the diet is not meticulously followed, according to a paper published online for subscribers in March in the journal Alzheimer's & Dementia: The Journal of the Alzheimer's Association.
National Institutes of Health

Contact: Nancy DiFiore
Rush University Medical Center

Public Release: 19-Mar-2015
Scripps Florida scientists win $1.5 million grant to develop new drugs for cancer
Scientists from the Florida campus of The Scripps Research Institute have been awarded a $1.5 million grant from the National Institutes of Health to develop drug candidates that could treat cancer and neurodegenerative disease. The researchers will look for compounds that affect a key enzyme involved in the degradation and ultimate recycling of damaged cellular material.
NIH/National Institute of General Medical Sciences

Contact: Eric Sauter
Scripps Research Institute

Public Release: 19-Mar-2015
American Journal of Public Health
Fewer multiple births could reduce autism risk in ART children
Scientists report that the incidence of diagnosed autism was twice as high for assisted reproductive technology (ART) as non-ART births among the nearly 6 million children in their study, born in California from 1997 through 2007. However, much of the association between ART and autism was explained by age and education of the mother as well as adverse perinatal outcomes, especially multiple births.
National Institutes of Health, NIH/National Institute of Mental Health

Contact: Eric Sharfstein
Columbia University

Public Release: 19-Mar-2015
Social Science & Medicine
Fast-food ban in L.A. fails to improve diets or cut obesity, study finds
In 2008, the city of Los Angeles passed a law restricting the opening or expansion of any 'stand-alone fast-food restaurant' in low-income neighborhoods where obesity was a problem. A new study finds the measure has failed to reduce fast-food consumption or reduce obesity rates in the targeted neighborhoods.
National Institutes of Health

Contact: Warren Robak
RAND Corporation

Showing releases 76-100 out of 3615.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 > >>


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