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Department of Health and Human Services

News from the National Institutes of Health

Funded News

Key: Meeting M      Journal J      Funder F

Showing releases 76-100 out of 3737.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 > >>

Public Release: 22-Jun-2015
JAMA Internal Medicine
Weight-loss surgery may greatly improve incontinence
For severely obese people, bariatric surgery may have a benefit besides dramatic weight loss: it can also substantially reduce urinary incontinence.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Elizabeth Fernandez
University of California - San Francisco

Public Release: 22-Jun-2015
Annals of Internal Medicine
Study finds most women with lupus can have good pregnancy outcomes
One of the most prevalent and anxiety-provoking concerns among patients with lupus is whether it is safe to become pregnant. A pioneering study led by researchers at Hospital for Special Surgery (HSS) has shown that most women can expect a good pregnancy outcome if their lupus is inactive and they are free of certain risk factors.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Robin Frank
Hospital for Special Surgery

Public Release: 22-Jun-2015
Penn: Mom's stress alters babies' gut and brain through vaginal microbiome
Stress during the first trimester of pregnancy alters the population of microbes living in a mother's vagina. Those changes are passed on to newborns during birth and are associated with differences in their gut microbiome as well as their brain development, according to a new study by University of Pennsylvania researchers.
NIH/National Institute of Mental Health

Contact: Katherine Unger Baillie
University of Pennsylvania

Public Release: 22-Jun-2015
Journal of the American College of Cardiology
'High-normal' blood pressure in young adults spells risk of heart failure in later life
Mild elevations in blood pressure considered to be in the upper range of normal during young adulthood can lead to subclinical heart damage by middle age -- a condition that sets the stage for full-blown heart failure, according to findings of a federally funded study led by scientists at Johns Hopkins.
NIH/National Heart, Lung, and Blood Institute, NIH/National Institute on Aging

Contact: Ekaterina Pesheva
Johns Hopkins Medicine

Public Release: 22-Jun-2015
Dual internal clocks keep plant defenses on schedule
Time management isn't just important for busy people -- it's critical for plants, too. A new study in the journal Nature shows how two biological clocks work together to help plants deal with intermittent demands such as fungal infections, while maintaining an already-packed daily schedule of activities like growth. The researchers also identified a gene that senses disturbances in the 'tick-tock' of one clock, and causes the other clock to tighten its timetable.
National Institutes of Health, US Department of Defense, Howard Hughes Medical Institute, Gordon and Betty Moore Foundation, Burroughs Wellcome Fund

Contact: Robin Ann Smith
Duke University

Public Release: 22-Jun-2015
Journal of Theoretical Biology
Model could help counteract poisoning from popular painkiller
New research could help reverse deadly side effects caused by excessive doses of the drug acetaminophen, the major ingredient in Tylenol and many other medicines. Duke University researchers have developed a mathematical model of acetaminophen metabolism based on data from rats. The findings suggest that giving patients glutamine -- a common amino acid in the body -- alongside the standard antidote for acetaminophen overdose could prevent liver damage and boost the body's ability to recover.
National Science Foundation, National Institutes of Health

Contact: Robin Ann Smith
Duke University

Public Release: 22-Jun-2015
Journal of Biological Chemistry
Researchers successfully target 'Achilles' heel' of MERS virus
Researchers studying the Middle East Respiratory Syndrome, or MERS, have found molecules that shut down the activity of an essential enzyme in the virus and could lead the way to better treatments for those infected. The team identified molecules that inhibit an enzyme essential to MERS virus replication, and also discovered a characteristic of the enzyme that is very different from other coronaviruses.
National Institutes of Health, Walther Cancer Foundation, US Department of Energy, Purdue Center for Cancer Research, Michigan Economic Development Corporation and Michigan Technology TriCorridor, Eli Lilly Company

Contact: Elizabeth K. Gardner
Purdue University

Public Release: 22-Jun-2015
Massachusetts General research team evolves CRISPR-Cas9 nucleases with novel properties
A team of Massachusetts General Hospital researchers has found a way to expand the use and precision of the powerful gene-editing tools called CRISPR-Cas9 RNA-guided nucleases. In their report receiving advance online release in Nature, the investigators describe evolved versions of the DNA-cutting Cas9 enzyme that are able to recognize a different range of nucleic acid sequences than is possible with the naturally occurring form of Cas9 that has been used to date.
National Institutes of Health, National Sciences and Engineering Research Council of Canada

Contact: Sue McGreevey
Massachusetts General Hospital

Public Release: 22-Jun-2015
Turning up the volume on prostate cancer
Rochester Institute of Technology professor Hans Schmitthenner is designing molecular imaging compounds that will selectively target prostate cancer cells and illuminate them with contrast dyes. An NIH grant is supporting the project and a team of undergraduate student researchers. The research is in the preclinical phase.
National Institutes of Health

Contact: Susan Gawlowicz
Rochester Institute of Technology

Public Release: 22-Jun-2015
Journal of Clinical Investigation
Rapid skin improvement seen after treating systemic sclerosis patients with fresolimumab
A major treatment breakthrough for total body scarring of the skin that occurs in patients with systemic sclerosis, also known as scleroderma, may soon be available for the estimated 300,000 Americans who suffer with this condition. Currently, no treatment is available.
NIH/National Institutes of Arthritis and Musculoskeletal and Skin Diseases

Contact: Gina DiGravio
Boston University Medical Center

Public Release: 22-Jun-2015
Molecular Cell
Unpacking the mysteries of bacterial cell cycle regulation
As part of their long-term investigation of regulatory factors in the bacterial cell cycle, molecular biologists at the University of Massachusetts Amherst now report finding a surprising new role for one factor, CpdR, an adaptor that helps to regulate selective protein destruction, the main control mechanism of cell cycle progression in bacteria, at specific times.
NIH/National Institute of General Medical Sciences, National Institutes of Health, University of Massachusetts Amherst

Contact: Janet Lathrop
University of Massachusetts at Amherst

Public Release: 22-Jun-2015
International Society on Thrombosis and Haemostasis
New England Journal of Medicine
Heart patients can stop blood thinners when undergoing elective surgery
Patients with atrial fibrillation who stopped taking blood thinners before they had elective surgery had no higher risk of developing blood clots and less risk of major bleeding compared to patients who were given a 'bridge' therapy, according to research led by Duke Medicine.
NIH/National Heart, Lung and Blood Institute

Contact: Sarah Avery
Duke University Medical Center

Public Release: 22-Jun-2015
Scientific Reports
Safe repellents that protect fruit from spotted wing Drosophila found
Scientists at the University of California, Riverside have identified a safe repellent that protects fruits from D. suzukii: Butyl anthranilate (BA), a pleasant-smelling chemical compound produced naturally in fruits in small amounts. In their lab experiments, the scientists found BA warded off D. suzukii from blueberries coated with it. The finding, when extrapolated to other agricultural pests, could provide a strategy for controlling them and increasing the productivity of crops and fruit.
NIH/National Institute on Deafness and Other Communication Disorders, UC Riverside

Contact: Iqbal Pittalwala
University of California - Riverside

Public Release: 22-Jun-2015
Annals of Internal Medicine
How can health professionals enhance cognitive health in older adults?
An expert panel convened by the Institute of Medicine clarified the cognitive aging process by making a distinction from Alzheimer's disease and related dementias, and provided recommendations to enhance cognitive health in older adults. Now a new article published in Annals of Internal Medicine highlights key points of that report and serves as a guide for health care professionals seeking to improve the quality of life of older adults by maintaining brain health.
NIH/National Institute on Aging

Contact: Dawn Peters
Hebrew SeniorLife Institute for Aging Research

Public Release: 22-Jun-2015
Annals of Internal Medicine
Pregnancy safer for women with lupus than previously thought
A new study concludes that most women with lupus whose disease is not very active will have a safe pregnancy. The study also identified several risk factors that might put some women with systemic lupus erythematosus at higher risk for bad outcomes in pregnancy.
NIH/National Institute of Arthritis, Musculoskeletal and Skin Diseases

Contact: Ryan Jaslow
NYU Langone Medical Center / New York University School of Medicine

Public Release: 22-Jun-2015
Nature Genetics
Saliva exonerated
A gene previously suspected of wielding the single greatest genetic influence on human obesity actually has nothing to do with body weight, according to a new study led by researchers at Harvard Medical School and Boston Children's Hospital.
National Institutes of Health

Contact: David Cameron
Harvard Medical School

Public Release: 22-Jun-2015
JAMA Internal Medicine
Millions of smokers may have undiagnosed lung disease
More than half of long-term smokers and ex-smokers who are considered disease-free because they passed lung-function tests have respiratory-related impairments when more closely evaluated with lung imaging, walking and quality-of-life tests. Many of those people likely have the earliest stages of chronic obstructive pulmonary disease, an incurable progressive disease that is the third leading cause of death in the United States.
National Institutes of Health, COPD Foundation

Contact: William Allstetter
National Jewish Health

Public Release: 22-Jun-2015
Journal of Clinical Investigation
A specially tailored gut microbiome alleviates hyperammonemia in mice
A new study in the Journal of Clinical Investigation demonstrates that alteration of the gut microbiome in mice can alleviate symptoms of hyperammonemia.
National Institutes of Health, Penn Center for Molecular Studies in Digestive and Liver Diseases

Contact: Corinne Williams
Journal of Clinical Investigation

Public Release: 22-Jun-2015
JAMA Internal Medicine
Current monitoring of pacemakers, defibrillators may underestimate device problems
The current monitoring of patients with cardiac implantable electronic devices such as pacemakers and defibrillators may be underestimating device problems, according to UC San Francisco researchers who propose systematic methods to determine accurate causes of sudden death in those with CIEDs as well as improved monitoring for device concerns
NIH/National Heart, Lung, and Blood Institute

Contact: Scott Maier
University of California - San Francisco

Public Release: 19-Jun-2015
NCI funds $3.1 million Fred Hutch clinical trial of a smoking-cessation smartphone app
Jonathan Bricker, Ph.D., a behavioral scientist at Fred Hutchinson Cancer Research Center and the University of Washington, has received a $3.1 million, five-year grant from the National Cancer Institute to conduct a randomized, controlled clinical trial of SmartQuit, a smoking-cessation smartphone app.
NIH/National Cancer Institute

Contact: Kristen Woodward
Fred Hutchinson Cancer Research Center

Public Release: 19-Jun-2015
Journal of Biological Rhythms
Access to electricity is linked to reduced sleep
New research comparing traditional hunter-gatherer living conditions to a more modern setting shows that access to artificial light and electricity has shortened the amount of sleep humans get each night.
Leakey Foundation, National Science Foundation, National Institutes of Health

Contact: James Urton
University of Washington

Public Release: 19-Jun-2015
Study shows sleep disturbances are common and influenced by race and ethnicity
A new study suggests that sleep disturbances and undiagnosed sleep apnea are common among middle-aged and older adults in the US, and these sleep problems occur more frequently among racial/ethnic minorities.
National Institutes of Health, National Center for Advancing Translational Sciences

Contact: Lynn Celmer
American Academy of Sleep Medicine

Public Release: 19-Jun-2015
AIDS and Behavior
PrEP is not linked to greater risk for depression
A new paper out of the iPrEx study--a randomized, placebo-controlled trial of daily oral HIV pre-exposure prophylaxis (PrEP) in men and transgender women who have sex with men -- reported no link between taking Truvada for oral PrEP and experiencing depression.
National Institutes of Health, Bill and Melinda Gates Foundation

Contact: Dana Smith
Gladstone Institutes

Public Release: 19-Jun-2015
Neurobiology of Disease
Scientists identify amino acid that stops seizures in mice
An amino acid whose role in the body has been all but a mystery appears to act as a potent seizure inhibitor in mice, according to a study by researchers at Johns Hopkins.
National Institutes of Health, Sutland-Pakula Family, Mathias Koch Memorial Fund

Contact: Ekaterina Pesheva
Johns Hopkins Medicine

Public Release: 19-Jun-2015
Discovery promises new treatments to thwart colon cancer
Scientists at St. Jude Children's Research Hospital have discovered how an immune system protein, called AIM2 (Absent in Melanoma 2), plays a role in determining the aggressiveness of colon cancer. They found that AIM2 deficiency causes uncontrolled proliferation of intestinal cells. Surprisingly, they also discovered that AIM2 influences the microbiota -- the population of gut bacteria -- apparently fostering the proliferation of 'good' bacteria that can protect against colon cancer.
National Institutes of Health, ALSAC

Contact: Carrie Strehlau
St. Jude Children's Research Hospital

Showing releases 76-100 out of 3737.

<< < 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 > >>


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