Feeding premature babies mostly breast milk during the first month of life appears to spur more robust brain growth. Those preemies whose daily diets were at least 50 percent breast milk had more brain tissue and cortical-surface area by their due dates than premature babies who consumed significantly less breast milk.
The connection between a family's income and childhood health has been well-established, with lower income linked to poorer health and a greater likelihood of more chronic conditions. Now a new study by UCLA researchers shows that the size of the paycheck is not all that matters when it comes to children's health risks. So does the amount that a family has tucked away in savings.
Ebola virus samples taken from Liberian patients in June 2015 are genetically similar to other Ebola virus sequences from Western Africa, according to research published today in Science Advances. The study sheds light on several aspects of the 'flare-ups' that have occurred in Liberia since the country was declared free of the disease. Among the findings: These cases were not a re-introduction from a neighboring country, but came from a persistently infected source within Liberia.
In recent years, hospitals have reported dramatic increases in the number of cases of the highly contagious, difficult-to-treat, and often deadly antibiotic-resistant bacteria carbapenem-resistant Enterobacteriaceae. Now, investigators at Beth Israel Deaconess Medical Center have developed a promising method of identifying new antimicrobials that target these organisms. The research is published in April issue of the journal ASSAY and Drug Development Technologies.
Strokes, seizures, traumatic brain injury and schizophrenia: these conditions can cause persistent, widespread acidity around neurons in the brain. But exactly how that acidity affects brain function isn't well understood.
University of Arizona Health Sciences, University of Pennsylvania and Vanderbilt University researchers are one step closer to understanding the genetic and biological basis of diseases like cancer, diabetes, Alzheimer's and rheumatoid arthritis -- and to identifying new drug targets and therapies.
Septin proteins in human and fungal cells can sense micron-scaled curves in the cell membrane, scientists from Dartmouth College and the Marine Biological Laboratory discover.
Using a clinically guided genetic screening approach, researchers identified a non-coding RNA that is overexpressed in triple-negative breast cancer cells and regulated by the tumor suppressor p53 and the activated cell surface protein, EGFR. This molecule enhances the repair of DNA breaks by serving as a scaffold that links two other proteins in the repair machinery.
The discovery of shared biological properties among independent variants of DNA sequences offers the opportunity to broaden understanding of the biological basis of disease and identify new therapeutic targets.
Ebola and other dangerous microbes often produce these inflammatory responses. Researchers at the Icahn School of Medicine at Mount Sinai say that tiny doses of a cancer drug may stop the raging, uncontrollable immune response to infection that leads to sepsis and kills up to 500,000 people a year in the US. The new drug treatment may also benefit millions of people worldwide who are affected by infections and pandemics.