The National Institutes of Health have awarded Dr. Evgeny Pavlov, assistant professor of basic science and craniofacial biology at the New York University College of Dentistry, a $1.8M, five-year grant to study the phenomenon known as the 'Mitochondrial Permeability Transition' to prevent strokes and heart attacks.
Whitehead Institute scientists have developed a method to quickly isolate mitochondria from mammalian cells and systematically measure the concentrations of mitochondrial metabolites. Mitochondrial dysfunction is found in several disorders, including Parkinson's disease, cardiovascular disease, and mitochondrial diseases. Until now, peering into the inner metabolic workings of these vital organelles has been very challenging.
An $11.3 million, five-year grant from the National Institutes of Health's Center of Biomedical Research Excellence will support Nebraska researchers as they investigate how the human body's cells communicate to function properly -- and how pathogens and environmental factors can disrupt that communication to cause disease.
A common cell signaling pathway that controls differentiation of stem cells may also control the formation of tumor cells in fat, according to a Purdue University study.
New study results provide insight into a long-observed, but little-understood connection between chronic pain and anxiety and offer a potential target for treatment. Researchers found that increased expression of PACAP -- a peptide neurotransmitter the body releases in response to stress -- is also increased in response to neuropathic pain and contributes to these symptoms.
New research from the University of Chicago investigates what happens to men's and women's sexual function and relationships after a heart attack in an effort to help clinicians develop better care guidelines for patients.
Do you feel overweight, about right, or too skinny? Your answer to that question may be tied to genes you inherited from your parents, especially if you are a female, according to a new study led by the University of Colorado Boulder.
Washington State University researchers have found that treatments of pure oxygen in a high-pressure chamber can relieve the symptoms of opiate withdrawal.
The Johns Hopkins University School of Medicine and the Salk Institute for Biological Studies will co-lead a $15.4 million effort to develop new systems for quickly screening libraries of drugs for potential effectiveness against schizophrenia and bipolar disorder, the National Institute of Mental Health has announced. The consortium, which includes four academic or nonprofit institutions and two industry partners, will be led by Hongjun Song of Johns Hopkins and Rusty Gage of Salk.
As an arm of the innate immune system, white blood cells called neutrophils form the first line of defense against invading pathogens. Neutrophils spend most of their lives racing through the bloodstream, patrolling for bacteria or other foreign particles. Once they arrive at tissues besieged by infectious agents, they halt on a dime and then blast through the vessel wall to reach the inflammatory attack site.