Cancer researchers have long observed the value of treating patients with combinations of anti-cancer drugs that work better than single drug treatments. Now, in a new study using laboratory-grown cells and mice, Johns Hopkins scientists report that a method they used to track metabolic pathways heavily favored by cancer cells provides scientific evidence for combining anti-cancer drugs, including one in a nanoparticle format developed at Johns Hopkins, that specifically target those pathways.
Thanks to new funding from the National Institute on Drug Abuse, researchers at the Lewis Katz School of Medicine at Temple University will explore the effects of the combination of tobacco smoke and opiates on the tissue damage that occurs in many patients infected with HIV.
A new study aims to better understand what makes some individuals particularly vulnerable to developing drug addiction. A team of researchers from across the country will look at how genes that influence brain function cause risk for addictions. J. David Jentsch, Empire Innovation Professor of psychology at Binghamton University, is part of the team of investigators awarded a new grant from the National Institute on Drug Abuse of the National Institutes of Health to conduct the research.
Researchers from Columbia University Medical Center (CUMC) found that men had greater pain relief than women after smoking marijuana. 'These findings come at a time when more people, including women, are turning to the use of medical cannabis for pain relief,' said Ziva Cooper, Ph.D., associate professor of clinical neurobiology (in psychiatry) at CUMC...
An international team led by scientists at The Scripps Research Institute has found strong evidence supporting a new strategy against drug addiction.
A new study at the University of Cincinnati looks at how young women's beliefs about alcohol and sex affect condom usage during sexual encounters involving alcohol.
A new study from scientists at The Scripps Research Institute, funded by the National Institutes of Health's National Institute on Drug Abuse and National Institute on Alcohol Abuse and Alcoholism, suggests that increased levels of a molecule in the brain, called hypocretin, may contribute to cocaine addiction. The research shows that blocking hypocretin may reduce compulsive drug-seeking behavior in rat models of cocaine addiction.
The National Institute on Drug Abuse of the National Institutes of Health has made a grant to The Jackson Laboratory to create a new Center for Systems Neurogenetics of Addiction.
Researchers compared self-reported sexual experiences related to use of alcohol and marijuana, to examine if and how marijuana use may influence risk for unsafe sexual behavior.
Clinicians should think twice when prescribing opioid medication to patients for the first time to relieve pain, migraines or severe coughs. To prevent possible addiction, doctors and pharmacists should err on the side of caution when considering dosages or subsequent refills. This was highlighted in a study¹ led by Richard Deyo of Oregon Health and Science University in the US, in the Journal of General Internal Medicine², published by Springer.