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Department of Health and Human Services

News from the National Institutes of Health

NIH Research News


Key: Meeting M      Journal J      Funder F

Showing releases 1-25 out of 99.

1 | 2 | 3 | 4 > >>

Public Release: 20-Aug-2014
JAMA
Test reliably detects inherited immune deficiency in newborns
A newborn screening test for severe combined immunodeficiency reliably identifies infants with this life-threatening inherited condition, leading to prompt treatment and high survival rates, according to a study supported by the National Institutes of Health. Researchers led by Jennifer Puck, M.D., of the University of California, San Francisco, also found that SCID affects approximately 1 in 58,000 newborns, indicating that the disorder is less rare than previously thought.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Hillary Hoffman
hillary.hoffman@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 20-Aug-2014
New England Journal of Medicine
Monthly blood transfusions reduce sickle cell anemia-related brain injury in children
Regular blood transfusions prevent recurrent blockage of brain blood vessels, a serious neurological side effect that occurs in one third of children with sickle cell anemia, according to a study funded by the National Institutes of Health. The findings appear in the Aug. 21 issue of the New England Journal of Medicine.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Heart Lung and Blood Institute

Contact: Barbara McMakin
nindspressteam@ninds.nih.gov
301-496-5751
NIH/National Institute of Neurological Disorders and Stroke

Public Release: 17-Aug-2014
Nature
Suspect gene corrupts neural connections
Researchers have demonstrated in patients' cells how a rare mutation in a suspect gene corrupts the turning on and off of dozens of other genes underlying synapses -- the connections between neurons. In a 'disease-in-a-dish' study, induced neurons of patients from families affected by a mutation associated with schizophrenia and other major mental illness expressed 80 percent lower-than-normal levels of a protein made by a suspect gene.
NIH/National Institute of Mental Health, NIH/National Institute of Neurological Disorders and Stroke

Contact: Jules Asher
NIMHpress@nih.gov
301-443-4536
NIH/National Institute of Mental Health

Public Release: 15-Aug-2014
Follow that cell
The National Institutes of Health is challenging science innovators to compete for prizes totaling up to $500,000, by developing new ways to track the health status of a single cell in complex tissue over time. The NIH Follow that Cell Challenge seeks tools that would, for example, monitor a cell in the process of becoming cancerous, detect changes due to a disease-causing virus, or track how a cell responds to treatment.
National Institutes of Health

Contact: Jules Asher
NIMHpress@nih.gov
301-443-4536
NIH/National Institute of Mental Health

Public Release: 14-Aug-2014
JAIDS: Journal of Acquired Immune Deficiency Syndromes
Scientists detail urgent research agenda to address chronic disease toll
According to recommendations resulting from a multidisciplinary conference sponsored by the National Institutes of Health, scientists and physicians in low- and middle-income countries should build on existing HIV research to study and treat chronic conditions.

Contact: Jeff Gray
Jeffrey.Gray@nih.gov
301-496-2075
NIH/Fogarty International Center

Public Release: 14-Aug-2014
The Lancet
Experimental chikungunya vaccine induces robust antibody response
An experimental vaccine to prevent the mosquito-borne viral illness chikungunya elicited neutralizing antibodies in all 25 adult volunteers who participated in a recent early-stage clinical trial conducted by researchers at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. The results are reported in the current issue of the Lancet.
NIH/National Institute of Allergy and Infectious Diseases

Contact: NIH/National Institute of Allergy and Infectious Diseases
niaidnews@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 14-Aug-2014
Cell
Scientists use lasers to control mouse brain switchboard
Using mice and flashes of light, scientists show that just a few nerve cells in the brain may control the switch between internal thoughts and external distractions. The study may be a breakthrough in understanding how a critical part of the brain, called the thalamic reticular nucleus, influences consciousness.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute of Mental Health, NIH/National Institute of General Medicine, National Science Foundation, Mathematical Biosciences Institute

Contact: Christopher G. Thomas
thomaschr@ninds.nih.gov
301-496-5751
NIH/National Institute of Neurological Disorders and Stroke

Public Release: 13-Aug-2014
New England Journal of Medicine
Ebola outbreak highlights global disparities in health-care resources
The outbreak of Ebola virus disease that has claimed more than 1,000 lives in West Africa this year poses a serious, ongoing threat to that region: the spread to capital cities and Nigeria -- Africa's most populous nation -- presents new challenges for healthcare professionals. The situation has garnered significant attention and fear around the world, but proven public health measures and sharpened clinical vigilance will contain the epidemic and thwart a global spread.
NIH/National Institute of Allergy and Infectious Diseases

Contact: NIAID Office of Communications
niaidnews@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 13-Aug-2014
NIH announces winners of 2014 Undergraduate Biomedical Engineering Competition
Four winning teams were announced in the Design by Biomedical Undergraduate Teams challenge, a biomedical engineering design competition for teams of undergraduate students.
NIH/National Institute of Biomedical Imaging and Bioengineering

Contact: Jessica Meade
nibibpress@mail.nih.gov
301-496-3500
NIH/National Institute of Biomedical Imaging & Bioengineering

Public Release: 13-Aug-2014
Nature
NIH-led scientists boost potential of passive immunization against HIV
Scientists are pursuing injections or intravenous infusions of broadly neutralizing HIV antibodies (bNAbs) as a strategy for preventing HIV infection. This technique, called passive immunization, has been shown to protect monkeys from a monkey form of HIV called simian human immunodeficiency virus, or SHIV. To make passive immunization a widely feasible HIV prevention option for people, scientists want to modify bNAbs such that a modest amount of them is needed only once every few months.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Laura S. Leifman
laura.sivitz@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 11-Aug-2014
Proceedings of the National Academy of Sciences
Bioengineers create functional 3-D brain-like tissue
Bioengineers have created three-dimensional brain-like tissue that functions like and has structural features similar to tissue in the rat brain and that can be kept alive in the lab for more than two months. The tissue could provide a superior model for studying normal brain function as well as injury and disease, and could assist in the development of new treatments for brain dysfunction.
NIH/National Institute of Biomedical Imaging and Bioengineering

Contact: Margot Kern
nibibpress@mail.nih.gov
301-496-3500
NIH/National Institute of Biomedical Imaging & Bioengineering

Public Release: 6-Aug-2014
New England Journal of Medicine
NIH and Italian scientists develop nasal test for human prion disease
A nasal brush test can rapidly and accurately diagnose Creutzfeldt-Jakob disease, an incurable and ultimately fatal neurodegenerative disorder, according to a study by National Institutes of Health scientists and their Italian colleagues.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Ken Pekoc
kpekoc@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 5-Aug-2014
PLOS Medicine
Year-round preventive treatment reduces malaria risk in young children
A year-round preventive drug treatment substantially reduces young children's risk of contracting malaria and poses no serious risk of adverse events, according to a study by researchers funded by the National Institutes of Health.The findings demonstrate that prolonged treatment given from six to 24 months of age is safe and effective for young children, according to the study authors.
National Institutes of Health, NIH/National Institute of Child Health and Human Development

Contact: Robert Bock or Meredith Daly
dalym@mail.nih.gov
301-496-5133
NIH/National Institute of Child Health and Human Development

Public Release: 30-Jul-2014
New England Journal of Medicine
Resistance to key malaria drug spreading at alarming rate in Southeast Asia
Resistance to artemisinin, the main drug to treat malaria, is now widespread throughout Southeast Asia, among the Plasmodium falciparum parasites that cause the disease and is likely caused by a genetic mutation in the parasites. However, a six-day course of artemisinin-based combination therapy -- as opposed to a standard three-day course -- has proved highly effective in treating drug-resistant malaria cases, according to findings published today in the New England Journal of Medicine.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Jennifer Routh
jennifer.routh@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 30-Jul-2014
Academic Medicine
Journal supplement details progress in African medical education
In the first substantial publication by participants of the $130 million Medical Education Partnership Initiative, more than 225 authors detailed progress made at African institutions in a 116-page supplement being published today by the journal Academic Medicine. The collection of 32 articles includes case studies of national strategies to increase numbers of doctors and health professionals trained; educational innovations such as e-learning; research capacity development; and partnerships that leverage advances across the MEPI network.
The President's Emergency Plan for AIDS Relief, National Institutes of Health

Contact: Jeff Gray
jeffrey.gray@nih.gov
301-496-2075
NIH/Fogarty International Center

Public Release: 27-Jul-2014
Nature Genetics
NIH scientists find 6 new genetic risk factors for Parkinson's
Using data from over 18,000 patients, scientists have identified more than two dozen genetic risk factors involved in Parkinson's disease, including six that had not been previously reported. The study, published in Nature Genetics, was partially funded by the National Institutes of Health and led by scientists working in NIH laboratories.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute on Aging, NIH/National Institute of Environmental Health Sciences

Contact: Barbara McMakin
nindspressteam@ninds.nih.gov
301-496-5751
NIH/National Institute of Neurological Disorders and Stroke

Public Release: 23-Jul-2014
NIBIB Edward C. Nagy New Investigator Symposium
NIBIB to host second Edward C. Nagy New Investigator Symposium
The National Institute of Biomedical Imaging and Bioengineering will host its second Edward C. Nagy New Investigator Symposium on July 30, 2014, on the NIH campus. There will be ten exciting presentations from recent new investigators covering a wide breadth of NIBIB-funded research.

Contact: Margot Kern
nibibpress@mail.nih.gov
301-496-3500
NIH/National Institute of Biomedical Imaging & Bioengineering

Public Release: 21-Jul-2014
Nature
NIH-supported scientists demonstrate very early formation of SIV reservoir
Scientists have generally believed that HIV and its monkey equivalent, SIV, gain a permanent foothold in the body very early after infection, making it difficult to completely eliminate the virus even after antiretroviral therapy has controlled it. Now NIH-supported researchers report that SIV can become entrenched in tissues fewer than three days after infection, before the virus is detectable in blood plasma or blood cells.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Laura S. Leifman
laura.sivitz@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 21-Jul-2014
Nature
Schizophrenia's genetic 'skyline' rising
The largest genomic dragnet of any psychiatric disorder to date has unmasked 108 chromosomal sites harboring inherited variations in the genetic code linked to schizophrenia, 83 of which had not been previously reported. By contrast, the 'skyline' of such suspect variants associated with the disorder contained only 5 significant peaks in 2011. Researchers combined data from all available schizophrenia genetic samples to boost statistical power high enough to detect subtle effects on risk.
National Institute of Mental Health

Contact: Jules Asher
NIMHpress@nih.gov
301-443-4536
NIH/National Institute of Mental Health

Public Release: 20-Jul-2014
Nature Genetics
Common gene variants account for most genetic risk for autism
Most of the genetic risk for autism comes from versions of genes that are common in the population rather than from rare variants or spontaneous glitches. Heritability also outweighed other risk factors in this largest study of its kind to date. About 52 percent of the risk for autism was traced to common and rare inherited variation, with spontaneous mutations contributing a modest 2.6 percent of the total risk.
National Institutes of Health

Contact: Jules Asher
NIMHpress@nih.gov
301-443-4536
NIH/National Institute of Mental Health

Public Release: 18-Jul-2014
Gastroenterology
High-dose fluticasone effective against eosinophilic esophagitis
Results from a clinical trial show that high doses of the corticosteroid fluticasone propionate safely and effectively induce remission in many people with eosinophilic esophagitis, a chronic inflammatory disease of the esophagus characterized by high levels of white blood cells called eosinophils. However, some trial participants did not respond to fluticasone even after six months of high-dose treatments, providing evidence that certain people with eosinophilic esophagitis are steroid-resistant.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Hillary Hoffman
hillary.hoffman@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 17-Jul-2014
NIH system to monitor emerging drug trends
An innovative National Drug Early Warning System is being developed to monitor emerging trends that will help health experts respond quickly to potential outbreaks of illicit drugs such as heroin and to identify increased use of designer synthetic compounds. The system will scan social media and Web platforms to identify new trends as well as use conventional national- and local-level data resources.
NIH/National Institute on Drug Abuse

Contact: NIDA Press Team
media@nida.nih.gov
301-443-6245
NIH/National Institute on Drug Abuse

Public Release: 16-Jul-2014
New England Journal of Medicine
NIH scientists identify gene linked to fatal inflammatory disease in children
Investigators have identified a gene that underlies a very rare but devastating autoinflammatory condition in children. Several existing drugs have shown therapeutic potential in laboratory studies, and one is currently being studied in children with the disease, which the researchers named STING-associated vasculopathy with onset in infancy. The findings appeared online today in the New England Journal of Medicine. The research was done at the National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the National Institutes of Health.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Trish Reynolds
reynoldsp2@mail.nih.gov
301-496-8190
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Public Release: 14-Jul-2014
Nature Genetics
Scientists deepen genetic understanding of eosinophilic esophagitis
Scientists funded by the National Institutes of Health have identified genetic markers associated with eosinophilic esophagitis, an inflammatory disease characterized by high levels of immune cells called eosinophils in the esophagus. Their findings suggest that several genes are involved in the development of EoE, which can cause difficulty eating and often is associated with food allergies. The findings also may help explain why the disease specifically affects the esophagus.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Hillary Hoffman
hillary.hoffman@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 10-Jul-2014
'Mississippi Baby' now has detectable HIV, researchers find
The child known as the 'Mississippi baby' -- an infant seemingly cured of HIV that was reported as a case study of a prolonged remission of HIV infection in the New England Journal of Medicine last fall -- now has detectable levels of HIV after more than two years of not taking antiretroviral therapy without evidence of virus, according to the pediatric HIV specialist and researchers involved in the case.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Kathy Stover
kathy.stover@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Showing releases 1-25 out of 99.

1 | 2 | 3 | 4 > >>

     
   

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