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Department of Health and Human Services

News from the National Institutes of Health

NIH Research News


Key: Meeting M      Journal J      Funder F

Showing releases 1-25 out of 93.

1 | 2 | 3 | 4 > >>

Public Release: 27-Jul-2014
Nature Genetics
NIH scientists find 6 new genetic risk factors for Parkinson's
Using data from over 18,000 patients, scientists have identified more than two dozen genetic risk factors involved in Parkinson's disease, including six that had not been previously reported. The study, published in Nature Genetics, was partially funded by the National Institutes of Health and led by scientists working in NIH laboratories.
NIH/National Institute of Neurological Disorders and Stroke, NIH/National Institute on Aging, NIH/National Institute of Environmental Health Sciences

Contact: Barbara McMakin
nindspressteam@ninds.nih.gov
301-496-5751
NIH/National Institute of Neurological Disorders and Stroke

Public Release: 23-Jul-2014
NIBIB Edward C. Nagy New Investigator Symposium
NIBIB to host second Edward C. Nagy New Investigator Symposium
The National Institute of Biomedical Imaging and Bioengineering will host its second Edward C. Nagy New Investigator Symposium on July 30, 2014, on the NIH campus. There will be ten exciting presentations from recent new investigators covering a wide breadth of NIBIB-funded research.

Contact: Margot Kern
nibibpress@mail.nih.gov
301-496-3500
NIH/National Institute of Biomedical Imaging & Bioengineering

Public Release: 21-Jul-2014
Nature
NIH-supported scientists demonstrate very early formation of SIV reservoir
Scientists have generally believed that HIV and its monkey equivalent, SIV, gain a permanent foothold in the body very early after infection, making it difficult to completely eliminate the virus even after antiretroviral therapy has controlled it. Now NIH-supported researchers report that SIV can become entrenched in tissues fewer than three days after infection, before the virus is detectable in blood plasma or blood cells.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Laura S. Leifman
laura.sivitz@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 21-Jul-2014
Nature
Schizophrenia's genetic 'skyline' rising
The largest genomic dragnet of any psychiatric disorder to date has unmasked 108 chromosomal sites harboring inherited variations in the genetic code linked to schizophrenia, 83 of which had not been previously reported. By contrast, the 'skyline' of such suspect variants associated with the disorder contained only 5 significant peaks in 2011. Researchers combined data from all available schizophrenia genetic samples to boost statistical power high enough to detect subtle effects on risk.
National Institute of Mental Health

Contact: Jules Asher
NIMHpress@nih.gov
301-443-4536
NIH/National Institute of Mental Health

Public Release: 20-Jul-2014
Nature Genetics
Common gene variants account for most genetic risk for autism
Most of the genetic risk for autism comes from versions of genes that are common in the population rather than from rare variants or spontaneous glitches. Heritability also outweighed other risk factors in this largest study of its kind to date. About 52 percent of the risk for autism was traced to common and rare inherited variation, with spontaneous mutations contributing a modest 2.6 percent of the total risk.
National Institutes of Health

Contact: Jules Asher
NIMHpress@nih.gov
301-443-4536
NIH/National Institute of Mental Health

Public Release: 18-Jul-2014
Gastroenterology
High-dose fluticasone effective against eosinophilic esophagitis
Results from a clinical trial show that high doses of the corticosteroid fluticasone propionate safely and effectively induce remission in many people with eosinophilic esophagitis, a chronic inflammatory disease of the esophagus characterized by high levels of white blood cells called eosinophils. However, some trial participants did not respond to fluticasone even after six months of high-dose treatments, providing evidence that certain people with eosinophilic esophagitis are steroid-resistant.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Hillary Hoffman
hillary.hoffman@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 17-Jul-2014
NIH system to monitor emerging drug trends
An innovative National Drug Early Warning System is being developed to monitor emerging trends that will help health experts respond quickly to potential outbreaks of illicit drugs such as heroin and to identify increased use of designer synthetic compounds. The system will scan social media and Web platforms to identify new trends as well as use conventional national- and local-level data resources.
NIH/National Institute on Drug Abuse

Contact: NIDA Press Team
media@nida.nih.gov
301-443-6245
NIH/National Institute on Drug Abuse

Public Release: 16-Jul-2014
New England Journal of Medicine
NIH scientists identify gene linked to fatal inflammatory disease in children
Investigators have identified a gene that underlies a very rare but devastating autoinflammatory condition in children. Several existing drugs have shown therapeutic potential in laboratory studies, and one is currently being studied in children with the disease, which the researchers named STING-associated vasculopathy with onset in infancy. The findings appeared online today in the New England Journal of Medicine. The research was done at the National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the National Institutes of Health.
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Contact: Trish Reynolds
reynoldsp2@mail.nih.gov
301-496-8190
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases

Public Release: 14-Jul-2014
Nature Genetics
Scientists deepen genetic understanding of eosinophilic esophagitis
Scientists funded by the National Institutes of Health have identified genetic markers associated with eosinophilic esophagitis, an inflammatory disease characterized by high levels of immune cells called eosinophils in the esophagus. Their findings suggest that several genes are involved in the development of EoE, which can cause difficulty eating and often is associated with food allergies. The findings also may help explain why the disease specifically affects the esophagus.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Hillary Hoffman
hillary.hoffman@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 10-Jul-2014
'Mississippi Baby' now has detectable HIV, researchers find
The child known as the 'Mississippi baby' -- an infant seemingly cured of HIV that was reported as a case study of a prolonged remission of HIV infection in the New England Journal of Medicine last fall -- now has detectable levels of HIV after more than two years of not taking antiretroviral therapy without evidence of virus, according to the pediatric HIV specialist and researchers involved in the case.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Kathy Stover
kathy.stover@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 9-Jul-2014
Nature
Study identifies novel genomic changes in the most common type of lung cancer
Researchers from The Cancer Genome Atlas Research Network have identified novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma, the most common subtype of lung cancer.
NIH/National Cancer Institute, NIH/National Human Genome Research Institute

Contact: Press Office
ncipressofficers@mail.nih.gov
301-496-6641
NIH/National Cancer Institute

Public Release: 9-Jul-2014
NIH launches Phase I clinical trial of novel drug to treat Clostridium difficile infection
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has launched an early-stage clinical trial of CRS3123, an investigational oral antibiotic intended to treat Clostridium difficile (C. difficile) infection. CRS3123 (previously known as REP3123) is a narrow-spectrum agent that inhibits C. difficile growth while sparing normal intestinal bacteria.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Jennifer Routh
jennifer.routh@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 9-Jul-2014
First drug candidate from NIH program acquired by biopharmaceutical company
A drug candidate developed by researchers at the NIH's National Center for Advancing Translational Sciences and its collaborators to treat sickle cell disease has been acquired by Baxter International's BioScience business. The drug candidate, Aes-103, is the first specifically developed to target the underlying molecular mechanism of sickle cell disease. Baxter now will advance the clinical development activities required for regulatory approval and commercialization.
National Institutes of Health

Contact: NCATS Office of Communications
spencerg@mail.nih.gov
301-435-0888
NIH/National Center for Advancing Translational Sciences (NCATS)

Public Release: 9-Jul-2014
Ophthalmology
Rehabilitation helps prevent depression from age-related vision loss
Depression is a common risk for people who have lost their vision from age-related macular degeneration, but a new study shows that a type of rehabilitation therapy can cut this risk in half. The study was funded by the National Eye Institute, part of the National Institutes of Health.
NIH/National Eye Institute

Contact: Jean Horrigan
neinews@nei.nih.gov
301-496-5248
NIH/National Eye Institute

Public Release: 8-Jul-2014
PLOS Medicine
NCI study finds extreme obesity may shorten life expectancy up to 14 years
Adults with extreme obesity have increased risks of dying at a young age from cancer and many other causes including heart disease, stroke, diabetes, and kidney and liver diseases, according to results of an analysis of data pooled from 20 large studies of people from three countries.
NIH/National Cancer Institute

Contact: NCI Press Officers
ncipressofficers@mail.nih.gov
301-496-6641
NIH/National Cancer Institute

Public Release: 8-Jul-2014
Nature Communications
Brain tumor invasion along blood vessels may lead to new cancer treatments
Invading glioblastoma cells may hijack cerebral blood vessels during early stages of disease progression and damage the brain's protective barrier, a study in mice indicates. This finding could ultimately lead to new ways to bring about the death of the tumor, as therapies may be able to reach these deadly cells at an earlier time point than was previously thought possible.
NIH/National Institute of Neurological Disorders and Stroke

Contact: Barbara McMakin
nindspressteam@ninds.nih.gov
301-496-5751
NIH/National Institute of Neurological Disorders and Stroke

Public Release: 8-Jul-2014
Archives of Toxicology
Low doses of arsenic cause cancer in male mice
Mice exposed to low doses of arsenic in drinking water, similar to what some people might consume, developed lung cancer, researchers at the National Institutes of Health have found.
NIH/National Institute of Environmental Health Sciences

Contact: Robin Mackar
rmackar@niehs.nih.gov
919-541-0073
NIH/National Institute of Environmental Health Sciences

Public Release: 7-Jul-2014
NIH funds next step of cutting-edge research into Alzheimer's disease genome
Teams of scientists will use support from the NIH to conduct research into the genetic underpinnings of Alzheimer's disease, analyzing how genome sequences may contribute to increased risk or protect against the disease. The NIH awarded grants for using innovative new technologies and computational methods for the analysis. The scientists also will seek insights into why some people with known risks do not develop the disease.
NIH/National Institute on Aging, NIH/National Human Genome Research Instiutute, National Institutes of Health

Contact: Peggy Vaughn
nianews3@mail.nih.gov
301-496-1752
NIH/National Institute on Aging

Public Release: 2-Jul-2014
New England Journal of Medicine
Acute kidney injury, chronic kidney disease each a risk of the other
Acute kidney injury and chronic kidney disease are closely intertwined, with each disease a risk factor for developing the other and sharing other risk factors in common, as well as sharing causes for the diseases to get worse, and outcomes, suggests a comprehensive analysis by scientists at the National Institutes of Health and George Washington University Medical Center, Washington, D.C. Findings were published July 3 in the New England Journal of Medicine.

Contact: Bill Polglase
NIDDKMedia@mail.nih.gov
301-496-3583
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Public Release: 2-Jul-2014
New England Journal of Medicine
Gene type confers 26 percent chance of early celiac sign by age 5
More than one quarter of children with two copies of a high-risk variant in a specific group of genes develop an early sign of celiac disease called celiac disease autoimmunity by age 5. The findings are from The Environmental Determinants of Diabetes in Youth consortium, or TEDDY.

Contact: Amy F. Reiter
NIDDKMedia@mail.nih.gov
301-496-3583
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Public Release: 1-Jul-2014
Nature Communications
NIH study reveals gene critical to the early development of cilia
Researchers at the National Eye Institute have described the functions of a gene responsible for anchoring cilia -- sensory hair-like extensions present on almost every cell of the body. The finding adds to an expanding body of knowledge about ciliopathies, a class of genetic disorders that result from defects in the structure or function of cilia.
National Eye Institute

Contact: Jean Horrigan
neinews@nei.nih.gov
301-496-5248
NIH/National Institute on Deafness and Other Communication Disorders

Public Release: 1-Jul-2014
JAMA
Adults stop anti-rejection drugs after stem-cell transplant reverses sickle cell disease
Half of patients in a trial have safely stopped immunosuppressant medication following a modified blood stem-cell transplant for severe sickle cell disease, according to a study in the July 1 issue of the Journal of the American Medical Association. The trial was conducted at the National Institutes of Health's Clinical Center in Bethesda, Md., by researchers from NIH's National Institute of Diabetes and Digestive and Kidney Diseases and the National Heart, Lung, and Blood Institute.

Contact: Krysten Carrera
NIDDKMedia@mail.nih.gov
301-496-3583
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Public Release: 30-Jun-2014
JAMA Pediatrics
Lead in kids' blood linked with behavioral and emotional problems
Emotional and behavioral problems show up even with low exposure to lead, and as blood lead levels increase in children, so do the problems, according to research funded by the National Institute of Environmental Health Sciences, part of the National Institutes of Health. The results were published online June 30 in the journal JAMA Pediatrics.
NIH/National Institute of Environmental Health Sciences

Contact: Robin Mackar
rmackar@niehs.nih.gov
919-541-0073
NIH/National Institute of Environmental Health Sciences

Public Release: 29-Jun-2014
Nature Medicine
NIH-funded researchers extend liver preservation for transplantation
Researchers have developed a new supercooling technique to increase the amount of time human organs could remain viable outside the body. This study was conducted in rats, and if it succeeds in humans, it would enable a world-wide allocation of donor organs, saving more lives.
National Institutes of Health, Shriners Hospitals for Children

Contact: Jessica Meade
nibibpress@mail.nih.gov
301-496-3500
NIH/National Institute of Biomedical Imaging & Bioengineering

Public Release: 26-Jun-2014
Nature
NIH scientists establish proof-of-concept for host-directed tuberculosis therapy
In a new study published in Nature, scientists describe a new type of tuberculosis treatment that involves manipulating the body's response to TB bacteria rather than targeting the bacteria themselves, a concept called host-directed therapy.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Jennifer Routh
jennifer.routh@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Showing releases 1-25 out of 93.

1 | 2 | 3 | 4 > >>

     
   

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