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Department of Health and Human Services

News from the National Institutes of Health

NIH Research News


Key: Meeting M      Journal J      Funder F

Showing releases 26-50 out of 88.

<< < 1 | 2 | 3 | 4 > >>

Public Release: 12-May-2015
Cell
Scientists unravel the mystery of the tubulin code
Driving down the highway, you encounter ever-changing signs -- speed limits, exits, food and gas options. Seeing these roadside markers may cause you to slow down, change lanes or start thinking about lunch. In a similar way, cellular structures called microtubules are tagged with a variety of chemical markers that can influence cell functions. The pattern of these markers makes up the 'tubulin code' and scientists have uncovered the mechanism behind one of the main writers of this code.

Contact: Barbara McMakin
nindspressteam@ninds.nih.gov
NIH/National Institute of Neurological Disorders and Stroke

Public Release: 11-May-2015
Diabetes
Ease of weight loss influenced by individual biology
For the first time in a lab, researchers at the National Institutes of Health found evidence supporting the commonly held belief that people with certain physiologies lose less weight than others when limiting calories. Study results published May 11 in Diabetes.

Contact: Krysten Carrera
NIDDKMedia@mail.nih.gov
301-496-3583
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Public Release: 7-May-2015
Science
New GTEx findings show how DNA differences influence gene activity, disease susceptibility
Researchers funded by the NIH Genotype-Tissue Expression project have created a data resource to help establish how differences in individual genomic make-up can affect gene activity and contribute to disease. It will enable scientists to examine the genomics of different human tissues and cells. Investigators reported findings from a pilot study, providing insights into how genomic variants control when and how much genes are turned on and off in tissues, and predispose people to disease.
NIH/National Human Genome Research Institute, NIH/National Institute of Mental Healt, NIH/Common Fund

Contact: Steven Benowitz
steven.benowitz@nih.gov
301-451-8325
NIH/National Human Genome Research Institute

Public Release: 7-May-2015
Science
Near-atomic resolution of protein structure by electron microscopy holds promise
A new study shows that it is possible to use an imaging technique called cryo-electron microscopy to view, in near-atomic detail, the architecture of a metabolic enzyme bound to a drug that blocks its activity. This advance provides a new path for solving molecular structures that may revolutionize drug development, noted the researchers.
NIH/National Cancer Institute

Contact: NCI Press Officers
ncipressofficer@mail.nih.gov
301-496-6641
NIH/National Cancer Institute

Public Release: 6-May-2015
Nature Communications
NIH study solves ovarian cell mystery, shedding new light on reproductive disorders
Scientists at the National Institutes of Health have solved a long-standing mystery about the origin of one of the cell types that make up the ovary. The team also discovered how ovarian cells share information during development of an ovarian follicle, which holds the maturing egg. Researchers believe this new information on basic ovarian biology will help them better understand the cause of ovarian disorders that result in hormone imbalances and infertility in women.
NIH/National Institute of Environmental Health Sciences

Contact: Robin Arnette
arnetter@niehs.nih.gov
919-541-5143
NIH/National Institute of Environmental Health Sciences

Public Release: 6-May-2015
Science Translational Medicine
Mobile phone microscope rapidly detects parasite levels in blood
Scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, and the University of California, Berkeley, and colleagues have developed a mobile phone microscope to measure blood levels of the parasitic filarial worm Loa loa. The point-of-care device may enable safe resumption of mass drug administration campaigns to eradicate the parasitic diseases onchocerciasis (river blindness) and lymphatic filariasis (elephantiasis).
NIH/National Institute of Allergy and Infectious Diseases

Contact: Hillary Hoffman
hillary.hoffman@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 4-May-2015
Nature Medicine
Study points to possible treatment for lethal pediatric brain cancer
Using brain tumor samples collected from children in the United States and Europe, an international team of scientists found that the drug panobinostat and similar gene regulating drugs may be effective at treating diffuse intrinsic pontine gliomas, an aggressive and lethal form of pediatric cancer.
National Institutes of Health, DIPG Collaborative, Cure Starts Now Foundation, Reflections of Grace Foundation, Smiles for Sophie Foundation, Cancer-Free Kids Foundation, Carly's Crusade Foundation and others

Contact: Christopher G. Thomas
thomaschr@ninds.nih.gov
30-149-657-511
NIH/National Institute of Neurological Disorders and Stroke

Public Release: 3-May-2015
2015 Association for Reseach in Vision and Ophthalmology annual meeting
New England Journal of Medicine
NIH-funded study points way forward for retinal disease gene therapy
Leber congenital amaurosis is an inherited disorder that causes vision loss starting in childhood. This is the latest report from an ongoing clinical trial of gene therapy for the disorder, funded by the National Eye Institute, part of the National Institutes of Health.
NIH/National Eye Institute

Contact: Kathryn DeMott, Joe Balintfy
neinews@nei.nih.gov
301-496-5248
NIH/National Eye Institute

Public Release: 1-May-2015
ARVO 2015 Annual Meeting
NIH launches research to gaze deeply into your eyes
Five bold projects will develop new technology to noninvasively image cells of the eye in unprecedented detail. The National Eye Institute (NEI) announced the awards as part of its Audacious Goals Initiative. NEI has committed $3.8 million to the projects in 2015 and up to $17.9 million over the next five years, pending the availability of funds. NEI is part of the National Institutes of Health.
NIH/National Eye Institute

Contact: Joe Balintfy
joe.balintfy@nih.gov
301-496-5248
NIH/National Eye Institute

Public Release: 30-Apr-2015
Neuron
Souped-up remote control switches behaviors on-and-off in mice
Neuroscientists have perfected a chemical-genetic remote control for brain circuitry and behavior. This evolving technology can now sequentially switch the same neurons -- and the behaviors they mediate -- on-and-off in mice, say researchers funded by the National Institutes of Health. Such bidirectional control is pivotal for decoding the brain workings of complex behaviors. The findings are the first to be published from the first wave of NIH grants awarded last fall under the BRAIN Initiative.
National Institutes of Health

Contact: Jules Asher
NIMHpress@nih.gov
301-443-4536
NIH/National Institute of Mental Health

Public Release: 29-Apr-2015
Nature
Brain circuitry for positive vs. negative memories discovered in mice
Neuroscientists have discovered brain circuitry for encoding positive and negative learned associations in mice. After finding that two circuits showed opposite activity following fear and reward learning, the researchers proved that this divergent activity causes either avoidance or reward-driven behaviors. They used cutting-edge optical-genetic tools to pinpoint these mechanisms critical to survival, which are also implicated in mental illness.
NIH/National Institute of Mental Health

Contact: Jules Asher
NIMHpress@nih.gov
301-443-4536
NIH/National Institute of Mental Health

Public Release: 25-Apr-2015
Pediatric Academic Societies Annual Meeting
New England Journal of Medicine
Two treatments yield similar results for children after cardiac arrest
A large-scale, multicenter study has shown that emergency body cooling does not improve survival rates or reduce brain injury in infants and children with out-of-hospital cardiac arrest more than normal temperature control. Until now, this treatment has not been studied in infants or children admitted to hospitals with cardiac arrest.
NIH/National Heart, Lung, and Blood Institute

Contact: NHLBI Engagement and Media Relations Branch
NHLBI_NEWS@nih.gov
301-496-4236
NIH/National Heart, Lung and Blood Institute

Public Release: 20-Apr-2015
Nature
Drugs that activate brain stem cells may reverse multiple sclerosis
Two drugs already on the market -- an antifungal and a steroid -- may potentially take on new roles as treatments for multiple sclerosis. According to a study published in Nature today, researchers discovered that these drugs may activate stem cells in the brain to stimulate myelin-producing cells and repair white matter, which is damaged in multiple sclerosis. The study was partially funded by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health.
NIH/National Institute of Neurological Disorders and Stroke, New York Stem Cell Foundation, Myelin Repair Foundation

Contact: Barbara McMakin
nindspressteam@ninds.nih.gov
NIH/National Institute of Neurological Disorders and Stroke

Public Release: 20-Apr-2015
American Journal of Tropical Medicine and Hygiene
Global pandemic of fake medicines poses urgent risk, scientists say
Poor quality medicines are an urgent threat that could undermine decades of successful efforts to combat HIV/AIDS, malaria and TB, according to the editors of a journal supplement published today. Scientists report up to 41 percent of specimens failed to meet quality standards in global studies of about 17,000 drug samples. Seventeen articles are included in the supplement 'The Global Pandemic of Falsified Medicines,' published by The American Journal of Tropical Medicine and Hygiene.
NIH/Fogarty International Center, Bill & Melinda Gates Foundation, New Venture Fund

Contact: Ann Puderbaugh
ann.puderbaugh@nih.gov
301-402-8614
NIH/Fogarty International Center

Public Release: 15-Apr-2015
NIH launches largest clinical trial focused on HIV-related cardiovascular disease
Researchers have begun enrolling participants in a multicenter international clinical trial to test whether a statin can reduce the risk of heart disease in people with HIV infection, who are up to twice as likely as people without HIV infection to have heart disease. The trial is supported by the National Heart, Lung, and Blood Institute and the National Institute of Allergy and Infectious Diseases, both part of the National Institutes of Health.
NIH/National Heart, Lung, and Blood Institute, NIH/National Institute of Allergy and Infectious Diseases

Contact: Laura S. Leifman
laura.sivitz@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 13-Apr-2015
NIH, South African Medical Research Council award $8 million in HIV, TB grants
NIH and the South African Medical Research Council are awarding 31 grants to US and South African scientists to support research targeting HIV/AIDS, tuberculosis and HIV-related co-morbidities and cancers. The awards, which total $8 million in first-year funding, are the first to be issued through the South Africa-US Program for Collaborative Biomedical Research.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Kathy Stover
niaidnews@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 13-Apr-2015
NIH still active in Gulf region 5 years after oil spill
Five years after the Deepwater Horizon oil rig explosion, researchers at the National Institutes of Health are actively working with Gulf region community partners, to learn if any human health problems resulted from the disaster and establish a new research response plan to be better prepared for future disasters.
NIH/National Institute of Environmental Health Sciences, National Institutes of Health

Contact: Robin Mackar
rmackar@niehs.nih.gov
919-541-0073
NIH/National Institute of Environmental Health Sciences

Public Release: 9-Apr-2015
NIH funds 9 antimicrobial resistance diagnostics projects
The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded more than $11 million in first-year funding for nine research projects supporting enhanced diagnostics to rapidly detect antimicrobial-resistant bacteria. The awardee institutions will develop tools to identify certain pathogens that frequently cause infections in health care settings and, specifically, those that are resistant to most antimicrobials.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Jennifer Routh
jennifer.routh@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 8-Apr-2015
Nature
Anti-HIV antibody shows promise in first human study
A single infusion of an experimental anti-HIV antibody called 3BNC117 resulted in significantly decreased HIV levels that persisted for as long as 28 days in HIV-infected individuals, according to Phase 1 clinical trial findings published online today in Nature. The research was led by long-time NIAID grantee Michel C. Nussenzweig, M.D., Ph.D., of the Howard Hughes Medical Institute at The Rockefeller University in New York City.

Contact: Robin Tricoles
robin.tricoles@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 8-Apr-2015
Science Translational Medicine
Allergy drug inhibits hepatitis C in mice
An over-the-counter drug indicated to treat allergy symptoms limited hepatitis C virus activity in infected mice, according to a National Institutes of Health study. The results suggest that the drug, chlorcyclizine HCl, potentially could be used to treat the virus in people. Results were published April 8 in Science Translational Medicine.

Contact: Krysten Carrera
NIDDKMedia@mail.nih.gov
301-496-3583
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Public Release: 6-Apr-2015
Proceedings of the National Academy of Sciences
NIH-funded scientists identify receptor for asthma-associated virus
Scientists funded by the National Institute of Allergy and Infectious Diseases have identified a cellular receptor for rhinovirus C, a cold-causing virus that is strongly associated with severe asthma attacks. A variant in the gene for this receptor previously had been linked to asthma in genetic studies, but the potential role of the receptor, called CDHR3, in asthma was unknown. The new findings help clarify the function of CDHR3 and point to a novel target for the development of prevention and treatment strategies against rhinovirus C-induced colds and asthma attacks.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Hillary Hoffman
hillary.hoffman@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 1-Apr-2015
NIBIB at NIH expert can provide comment on current state of robotics in surgery
Johnson & Johnson announced a collaboration with Google on March 26, 2015, to advance surgical robots by integrating medical device technology with robotic systems, imaging and data analytics; National Institute of Biomedical Imaging and Bioengineering at the National Institutes of Health can provide comment on state of the science.

Contact: Margot Kern
nibibpress@mail.nih.gov
301-496-3500
NIH/National Institute of Biomedical Imaging & Bioengineering

Public Release: 1-Apr-2015
New England Journal of Medicine
Experimental Ebola vaccine safe, prompts immune response
An early-stage clinical trial of an experimental Ebola vaccine conducted at the National Institutes of Health and the Walter Reed Army Institute of Research found that the vaccine, called VSV-ZEBOV, was safe and elicited robust antibody responses in all 40 of the healthy adults who received it.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Anne A. Oplinger
aoplinger@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 30-Mar-2015
Advances in Neonatal Care
Promoting maternal interaction improves growth, weight gain in preemies
An intervention to teach mothers of preterm infants how to interact with their babies more effectively results in better weight gain and growth for the infants, according to a study funded in part by the National Institutes of Health.
National Institutes of Health

Contact: Robert Bock
bockr@mail.nih.gov
301-496-5133
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development

Public Release: 26-Mar-2015
Ebola test vaccines appear safe in phase 2 Liberian clinical trial
Two experimental Ebola vaccines appear to be safe based on evaluation in more than 600 people in Liberia who participated in the first stage of the Partnership for Research on Ebola Vaccines in Liberia Phase 2/3 clinical trial, according to interim findings from an independent Data and Safety Monitoring Board review. Based on these findings, the study, which is sponsored by the NIAID, part of the National Institutes of Health, may now advance to Phase 3 testing.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Jennifer Routh
Jennifer.routh@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases

Showing releases 26-50 out of 88.

<< < 1 | 2 | 3 | 4 > >>

     
   

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