In the present multicenter study, a positive association was identified between OCD and a sequence variant of a serotonergic receptor gene (A-allele of the 5-HT2A-receptor promoter polymorphism –1438G/A). The association suggests that this genetic phenotype is a risk factor for early onset OCD and may represent either a direct or an indirect influence on development of this disorder. The results also indicate that molecular genetic studies should consider age of onset when investigating disease etiology and risk factors.
Citation source: Molecular Psychiatry 2002 Volume 7, number 10, pages 1054-1057.
For further information on this work, please contact Dr. Susanne Walitza, Department of Child and Adolescent Psychiatry, Julius-Maximilians University, Fuechsleinstrasse 15, Wuerzburg, 97080, Germany. Phone: 49-931-201-7801. Fax: 49-931-201-7804 firstname.lastname@example.org
Molecular Psychiatry is published by the Nature Publishing Group. http://www.nature.com/mp
Editor: Julio Licinio, M.D.; phone: 310-825-7113; FAX: 310-206-6715; e-mail: email@example.com
For a copy of this article, please contact Aimee Midei, editorial assistant, e-mail: firstname.lastname@example.org.
PLEASE CITE MOLECULAR PSYCHIATRY AS THE SOURCE OF THIS MATERIAL.
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.