News Release

Algorithm for mapping mild cognitive impairment

Peer-Reviewed Publication

PLOS

Despite intensive use of the term “mild cognitive impairment” (MCI) to describe an intermediate stage of cognitive decline between normal and pathological brain ageing, no formally agreed process of characterizing this condition exists, say Fiona Matthews (MRC Biostatistics Unit, Cambridge, UK) and colleagues.

Current classifications of MCI, they say, define heterogeneous populations with different patterns of etiology, cognitive decline, and clinical outcome. They present a new framework, which includes an online diagnostic algorithm (http://www.cfas.ac.uk/mciprogram/), for mapping the different classifications of MCI (such as “benign senescent forgetfulness” and “amnestic MCI”).

###

Citation: Matthews FE, Stephan BCM, Bond J, McKeith I, Brayne C on behalf of the Medical Research Council Cognitive Function and Ageing Study (2007) Operationalisation of mild cognitive impairment: A graphical approach. PLoS Med 4(0): e304.

PLEASE ADD THE LINK TO THE PUBLISHED ARTICLE IN ONLINE VERSIONS OF YOUR REPORT: http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pmed.0040304

PRESS-ONLY PREVIEW OF THE ARTICLE: http://www.plos.org/press/plme-04-10-matthews.pdf

Related image for press use: http://www.plos.org/press/plme-04-10-matthews.jpg

- Caption: Brain MRI

CONTACT:
FionaMatthews
MRC Biostatistics Unit
Institute of Public Health
Forvie Site
Robinson Way
Cambridge, CB2 2SR
United Kingdom
+44 1223 330391
+44 1223 330388 (fax)
Fiona.Matthews@mrc-bsu.cam.ac.uk

About PLoS Medicine

PLoS Medicine is an open access, freely available international medical journal. It publishes original research that enhances our understanding of human health and disease, together with commentary and analysis of important global health issues. For more information, visit http://www.plosmedicine.org

About the Public Library of Science

The Public Library of Science (PLoS) is a non-profit organization of scientists and physicians committed to making the world's scientific and medical literature a freely available public resource. For more information, visit http://www.plos.org


Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.