Diesel exhaust causes arteries to lose their flexibility. Researchers writing in BioMed Central's open access journal Particle and Fibre Toxicology found that exposure to engine pollution resulted in arterial stiffness in a group of healthy volunteers.
Nicholas Mills from the University of Edinburgh worked with a team of researchers to investigate the cardiovascular damage that can be caused by inhaling diesel smoke. He said, "Acute exposure to diesel exhaust is associated with an immediate and transient increase in arterial stiffness. This may, in part, explain the increased risk for cardiovascular disease associated with air pollution exposure".
The authors invited a group of 12 non-smoking young men to cycle on exercise bikes while breathing air that had either been filtered or been contaminated with smoke from a diesel engine. They found that when the subjects were exposed to the polluted air, the blood vessels in their wrists temporarily lost the ability to expand and contract. According to Mills, this can have serious consequences, "Stiff arteries can result in raised blood pressure and reduced blood flow in the heart. Arterial stiffness plays an important role in hypertension and is an independent predictor of mortality."
There is, however, something that cyclists and pedestrians in smog shrouded cities can do to limit the vascular effects caused by diesel exhaust. In a separate article also published in Particle and Fibre Toxicology, researchers report how wearing a facemask reduces exposure to airborne pollution particles and leads to a reduction blood pressure and improved heart rate control during exercise in a city centre environment. Jeremy Langrish from the University of Edinburgh said, "We tested a range of facemasks that differed widely in their efficiency as particle filters. In general, those masks designed to reduce occupational exposure to dusts in the workplace were more efficient than those marketed to cyclists and pedestrians."
The authors say, "This simple intervention has the potential to protect susceptible individuals and reduce cardiovascular events in cities with high concentrations of ambient air pollution."
Notes to Editors
1. Beneficial Cardiovascular Effects of Reducing Exposure to Particulate Air Pollution with a Simple Facemask
Jeremy P Langrish, Nicholas L Mills, Julian KK Chan, Daan LAC Leseman, Robert J Aitken, Paul HB Fokkens, Flemming R Cassee, Jing Li, Ken Donaldson, David E Newby and Lixin Jiang
Particle and Fibre Toxicology (in press)
During embargo, article available here: http://www.particleandfibretoxicology.com/imedia/6787327402471325_article.pdf?random=656772
Experimental exposure to diesel exhaust increases arterial stiffness in man
Magnus Lundback, Nicholas L Mills, Andrew Lucking, Stefan Barath, Ken Donaldson, David E Newby, Thomas Sandstrom and Anders Blomberg
Particle and Fibre Toxicology
During embargo, article available here: http://www.particleandfibretoxicology.com/imedia/1120170961226081_article.pdf?random=658418
After the embargo, articles available at journal website: http://www.particleandfibretoxicology.com/
Please name the journal in any story you write. If you are writing for the web, please link to the article. All articles are available free of charge, according to BioMed Central's open access policy.
Article citation and URL available on request at firstname.lastname@example.org on the day of publication
2. Particle and Fibre Toxicology is interested in receiving manuscripts which report new scientific data, hypotheses and reviews on the toxicological effects of particles and fibres. The journal functions as a forum for scientific debate and communication between toxicology and disciplines that develop (nano)particles for future applications.
3. BioMed Central (http://www.biomedcentral.com/) is an STM (Science, Technology and Medicine) publisher which has pioneered the open access publishing model. All peer-reviewed research articles published by BioMed Central are made immediately and freely accessible online, and are licensed to allow redistribution and reuse. BioMed Central is part of Springer Science+Business Media, a leading global publisher in the STM sector.
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.