A collaboration of French and Canadian researchers have found that sucking a portion of a spherical globule of cells into a tiny pipette provides information about the adhesion between cells and the elastic properties of the tissue. The method is a novel approach for the study of the structural properties of tissues, and should offer insights into processes such as embryonic development, tissue growth and cancer. A paper describing the research appears online in Physical Review Letters on May 24.
Conventional techniques for measuring the structural properties of tissues typically involved placing a sample between a pair of plates and observing how the tissue responds to compression. The new pipette technique complements the parallel plate method, as well as allowing researchers to obtain a wider range of measurements. In addition, the pipette approach could potentially allow for measurements to be performed on living tissue in its natural environment.
In a Viewpoint article in the current issue of APS Physics (http://physics.
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