[ Back to EurekAlert! ] Public release date: 25-May-2010
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Contact: Lindy Brouwer
European Association of Urology

European Urology: Editorial about REDUCE trial underlines value of dutasteride

Arnhem -- On 8 May an editorial about the Reduction by Dutasteride of Prostate Cancer Events (REDUCE) trial by Fritz H. Schröder and Monique J. Roobol was published in the online version of European Urology, the scientific journal of the European Association of Urology (EAU).

The long-expected final report of the REDUCE trial appeared on April 1, 2010 in the New England Journal of Medicine [1] together with a commentary entitled 'Chemoprevention of prostate cancer' by Dr Patrick Walsh. What were the noteworthy items of the editorial?



  1. Andriole GL, Bostwick DG, Brawley OW, Gomella LG, Marberger M, Montorsi F, Pettaway CA, Tammela TL, Teloken C, Tindall DJ, Somerville MC, Wilson TH, Fowler IL, Rittmaster RS, for the REDUCE Study Group. Effect of Dutasteride on the risk of prostate cancer. N Eng J Med. 2010 April 1 362;13.
  2. Thompson IM, Goodman PJ, Tangen CM, Lucia MS, Miller GJ, Ford GJ, Lieber MM, Cespedes RD, Atkins JN, Lippman SM, Carlin SM, Ryan A, Szczepanek CM, Crowley JJ, Coltman CA Jr. The influence of finasteride on the development of prostate cancer. N Engl J Med. 2003 Jul 17;349(3):215-24.
  3. Gleave M, Qian J, Andreou C, Pommerville P, Chin J, Casey R, Steinhoff G, Fleshner N, Bostwick D, Thomas L, Rittmaster R. The effects of the dual 5alpha-reductase inhibitor dutasteride on localized prostate cancer--results from a 4-month pre-radical prostatectomy study. Prostate. 2006 Nov 1;66(15):1674-85.
  4. Schröder FH, Roobol MJ. The REDUCE Trial. Eur Urol (2010), doi:10.1016/j.eururo.2010.04.031, http://www.europeanurology.com

For more information, please contact Lindy Brouwer, EAU Communication Officer, at l.brouwer@uroweb.org.

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