Irvine, Calif. - Healthier cafeteria choices, longer and more intense periods of physical activity and robust in-school education programs can lower rates of obesity and other risk factors for type 2 diabetes, according to a national study called HEALTHY.
The findings will be presented Sunday, June 27, at the American Diabetes Association's 70th Scientific Sessions event in Orlando, Fla., and will appear online and in the June 29 issue of The New England Journal of Medicine.
UC Irvine was among eight academic medical centers nationwide chosen to participate in the three-year effort, funded by the National Institute of Diabetes and Digestive & Kidney Diseases, a branch of the National Institutes of Health, and the American Diabetes Association.
"We found that innovative PE programs, healthier food choices in school lunches and snacks, and in-class lessons in healthy lifestyles can benefit those children most at-risk for developing type 2 diabetes and related conditions," says pediatrics professor Dr. Dan M. Cooper, UC Irvine's principal investigator for HEALTHY. "Because we worked with the existing school infrastructure, the lessons learned from this study can be readily applied throughout the nation."
Because type 2 diabetes disproportionately affects minorities and low-income people, the study was conducted in U.S. schools with high enrollments of minority children - 54 percent Latino and 18 percent African American, on average - and kids from low-income families. UCI partnered with middle schools in the Long Beach Unified School District: Bancroft, DeMille, Hoover, Hughes, Marshall and Stephens.
Nationwide, 4,603 students in 42 middle schools were tracked from the beginning of sixth grade through the completion of eighth grade. Half the schools were randomly chosen to implement the study's "intervention" program of longer gym classes, more nutritious food choices, classroom education units and other schoolwide activities encouraging healthy behaviors.
The "comparison" schools got no specific intervention but did receive discretionary funds for food options and physical activities of their own choosing. Parents at all UCI-participant schools were given written feedback on student health screenings and notified if their children were found to be at high risk for diabetes.
At the beginning of the study, many sixth-graders at both intervention and comparison schools were considered in jeopardy. Nearly half were overweight or obese, 16 percent had elevated fasting blood glucose levels, and nearly 7 percent had elevated fasting insulin levels - all risk factors for developing type 2 diabetes.
At the end of the study, researchers found that the then-eighth-grade students in intervention schools who had been overweight or obese in sixth grade had a 21 percent lower rate of obesity than their counterparts in comparison schools. Students at intervention schools also had lower average levels of fasting insulin and smaller average waist circumferences.
Surprisingly, the number of overweight and obese students declined in both intervention and comparison schools. Additionally, the study groups did not differ in mean glucose levels or the percentage of students with elevated fasting glucose in the overweight category.
"We do not completely understand why there were improvements in both the intervention and comparison schools," Cooper says. "We do know, however, that in our schools here in Long Beach, many of the innovative approaches to PE and school food choices that we started in the intervention schools found their way to the comparison schools as well. The teachers and staff in the school system are very concerned about the problem of obesity and are always looking for ways to improve the health of children."
Over the course of the study, intervention schools provided students with low-fat, high-fiber foods and more fruits and vegetables, with an emphasis on water, low-fat milk and drinks with no added sugar. These students also had longer, more intense periods of physical activity - defined as achieving a heart rate of at least 140 beats per minute, with a target of 150 minutes or more of such activity every 10 days. And they were involved in highly interactive, small-group classroom activities and awareness campaigns promoting long-term healthy behaviors.
Other research centers participating in the study were: Baylor College of Medicine in Houston; George Washington University in Washington, D.C.; Oregon Health & Science University in Portland; Temple University in Philadelphia; University of North Carolina at Chapel Hill; University of Pittsburgh Medical Center; and University of Texas Health Science Center at San Antonio. For more information about the study, see www.healthystudy.org.
About Diabetes: Afflicting approximately 24 million Americans, diabetes is the primary cause of kidney failure, limb amputation and adult-onset blindness and is a major contributor to heart disease and stroke. The longer a person has diabetes, the greater the chances of serious damage to the eyes, nerves, heart, kidneys and blood vessels. Type 2 diabetes, which accounts for up to 95 percent of all diabetes cases, becomes more common with age. It's strongly associated with obesity, inactivity, family history, impaired glucose metabolism, and racial or ethnic background. The prevalence of diagnosed diabetes has more than doubled in the last 30 years, due in large part to the upsurge in obesity. For more information, visit www.diabetes.org.
About the National Institute of Diabetes and Digestive & Kidney Diseases: NIDDK conducts and supports basic and clinical research and research training on some of the most common, severe and disabling conditions affecting Americans. Its research interests include diabetes and other endocrine and metabolic diseases; digestive diseases, nutrition and obesity; and kidney, urological and hematologic diseases. For more information, visit www.niddk.nih.gov.
About the University of California, Irvine: Founded in 1965, UCI is a top-ranked university dedicated to research, scholarship and community service. Led by Chancellor Michael Drake since 2005, UCI is among the most dynamic campuses in the University of California system, with nearly 28,000 undergraduate and graduate students, 1,100 faculty and 9,000 staff. Orange County's largest employer, UCI contributes an annual economic impact of $3.9 billion. Its Department of Pediatrics is affiliated with CHOC Children's Hospital in Orange. For more UCI news, visit www.today.uci.edu.
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