[ Back to EurekAlert! ]

PUBLIC RELEASE DATE:
27-Oct-2010

[ | E-mail ] Share Share

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
@ACSpressroom

Cone of poison: The secret behind the cone snail's venom pump

Scientists have discovered the secret of how an amazing sea snail injects its venom after shooting a harpoon-like tooth into its prey -- or some unlucky swimmer -- at jetliner speeds. The creatures, called cone snails, use a highly specialized structure that instantly pumps the paralyzing venom through the tooth and into its target. Their study appears in ACS' monthly Journal of Proteome Research.

Helena Safavi-Hemami, Anthony Purcell and colleagues note that cone snails live mainly in the shallows of the world's tropical oceans. Prized by sea-shell collectors for their beautiful shells, the snails are up to 9 inches long. Their mouths have a blow-gun-like structure that shoots a barbed dart-like "tooth" at about 400 miles per hour. The tooth injects venom into fish, worms, or other prey. The snails occasionally sting swimmers, causing pain and sometimes death. They can reload the shooter with additional harpoons. The venom is produced in the venom duct, a long tube attached to the harpoon on one end and to the venom bulb in the snail's mouth.

The scientists' analysis of proteins in venom bulbs found high concentrations of arginine kinase, a protein that enables squid and scallops to swim away from danger with extreme speed. Its abundance in the bulb suggests that arginine kinase enables the venom bulb to undergo rapid, repeated contractions to quickly force the venom through the venom duct to the harpoon and into the prey, the scientists say. The scientists also identified specialized muscles in the venom bulb that appear to aid in this process.

###

ARTICLE FOR IMMEDIATE RELEASE
"Proteomic interrogation of venom delivery in marine cone snails - Novel insights into the role of the venom bulb"

DOWNLOAD FULL TEXT ARTICLE
http://pubs.acs.org/stoken/presspac/presspac/full/10.1021/pr100431x

CONTACT:
Anthony Wayne Purcell, Ph.D.
Department of Biochemistry and Molecular Biology
University of Melbourne
Victoria, Australia
Phone: (+61 3) 8344 2288
Email: apurcell@unimelb.edu.au



[ Back to EurekAlert! ] [ | E-mail Share Share ]

 


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.