[ Back to EurekAlert! ] Public release date: 4-Oct-2010
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Contact: Maggie Francis
maggie.francis@heart.org
214-706-1382
American Heart Association

Guidelines on using artery-closing devices: devices are OK, but more research needed

Re-opening a blocked heart artery isn't the only procedure that concerns doctors when they thread instruments through an opening in a thigh artery and into a heart artery. Closing up the thigh artery is also a concern.

Arteriotomy the process of creating a hole in an "access artery" through which instruments are inserted is the first step in procedures like angiography (to visualize blockage in the heart or neck arteries) or percutaneous coronary intervention (to re-open blocked heart arteries).

A new statement from the American Heart Association addresses the use of arteriotomy closure devices. Arteriotomy closure is typically done manually, but more devices are entering the market to offer potential improvements over manual closure. The statement is published in Circulation: Journal of the American Heart Association.

The statement authors conclude that the devices are reasonable to use and they offer recommendations for their use based on available evidence but their benefits should be weighed against the risk of complications in patients. Patient-specific factors like age, gender, and disease severity should be considered before using an arteriotomy closure device.

The statement also includes recommendations for future trials and end points needed to inform clinical practice.

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Co-authors are: Hani Jneid, M.D.; Colin P. Derdeyn, M.D.; Lloyd W. Klein, M.D.; Glenn N. Levine, M.D.; Robert Lookstein, MD, FAHA; Christopher J. White, M.D.; Yerem Yeghiazarians, M.D.; and Kenneth Rosenfield, M.D. Author disclosures are on the manuscript.

Related statistics:

The American Heart Association/American Stroke Association receives funding mostly from individuals. Foundations and corporations donate as well, and fund specific programs and events. Strict policies are enforced to prevent these relationships from influencing the association's science content. Financial information for the American Heart Association, including a list of contributions from pharmaceutical companies and device manufacturers, is available at www.heart.org/corporatefunding.



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