Colonoscopy is considered a safe procedure, although complications can occur. The most dreaded of these is iatrogenic perforation. The literature reports perforation rates of 0.03%-0.8% for diagnostic procedures, and a rate of 0.15%-3% for therapeutic procedures. Mechanisms of perforation are the result of either mechanical disruption of the colonic wall (e.g. thermal injury, forced push into a diverticulum, or stretching of the bowel with loops or the slide-by technique) or excessive air insufflation. After perforation, prompt abdominal surgery is usually recommended, particularly in the last few years, following the introduction of laparoscopic approaches in clinical practice. Nevertheless, conservative treatment is a feasible and effective option for patients who are clinically stable and without peritonism or life threatening signs.
A research article published on February 28, 2011 in the World Journal of Gastroenterology addresses this question. The authors reported a case of a 63-year-old male who experienced an iatrogenic sigmoid perforation repaired combining three endoscopic techniques.
The lesion was large and irregular with three discrete perforations, therefore, the authors decided to close it by placing one clip per perforation, and then connecting all the clips with two endoloops. Finally they chose to use a fibrin glue injection to obtain a complete sealing. Four days after the colonoscopy the patient underwent a laparoscopic right hemicolectomy due to evidence of a large polyp of the caecum with high grade dysplasia and focal carcinoma in situ . Inspection of the sigma showed complete repair of the perforation.
This report underlines how a conservative approach, together with a combination of various endoscopic techniques, can resolve complicated perforations without the need for surgical intervention.
Reference: Mocciaro F, Curcio G, Tarantino I, Barresi L, Spada M, Li Petri S, Traina M. Tulip bundle technique and fibrin glue injection: Unusual treatment of colonic perforation. World J Gastroenterol 2011; 17(8): 1088-1090
Correspondence to: Filippo Mocciaro, MD, PhD, Department of Gastroenterology, IsMeTT, Via Tricomi 1, Palermo 90100, Italy. firstname.lastname@example.org
Telephone: +39-91-900347 Fax: +39-91-2192400
About World Journal of Gastroenterology
World Journal of Gastroenterology (WJG), a leading international journal in gastroenterology and hepatology, has established a reputation for publishing first class research on esophageal cancer, gastric cancer, liver cancer, viral hepatitis, colorectal cancer, and H. pylori infection and provides a forum for both clinicians and scientists. WJG has been indexed and abstracted in Current Contents/Clinical Medicine, Science Citation Index Expanded (also known as SciSearch) and Journal Citation Reports/Science Edition, Index Medicus, MEDLINE and PubMed, Chemical Abstracts, EMBASE/Excerpta Medica, Abstracts Journals, Nature Clinical Practice Gastroenterology and Hepatology, CAB Abstracts and Global Health. ISI JCR 2009 IF: 2.092. WJG is a weekly journal published by WJG Press. The publication dates are the 7th, 14th, 21st, and 28th day of every month. WJG is supported by The National Natural Science Foundation of China, No. 30224801 and No. 30424812, and was founded with the name of China National Journal of New Gastroenterology on October 1, 1995, and renamed WJG on January 25, 1998.
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.