HONOLULU – New evidence suggests that walking on a treadmill at a comfortable speed and for longer duration is the most effective exercise to improve mobility in people with Parkinson's disease. That's according to the first randomized trial comparing three types of exercise training in Parkinson's disease. The late-breaking research will be presented at the 63rd Annual Meeting of the American Academy of Neurology, April 9, 2011, in Honolulu.
"Difficulty walking is the greatest cause of disability in people with Parkinson's disease," said Lisa M. Shulman, MD, with the University of Maryland School of Medicine in Baltimore and a Fellow of the American Academy of Neurology. "These results have important implications for how we manage Parkinson's disease, since low-intensity exercise can be done by most people with Parkinson's, and our patients frequently ask what type of exercise they should be doing."
In this study, 67 people with Parkinson's disease who had problems with walking were randomly assigned to three types of exercise: high intensity treadmill (greater speed, shorter duration), low intensity treadmill (lower speed, longer duration) or stretching and resistance exercises, which included repetitions of leg presses, extensions and curls.
Participants exercised three times a week for three months and were supervised by exercise physiologists at the Baltimore VA Medical Center. They were tested before and after the training with assessments of distance covered in a six-minute walk, walking speed at 10 meters and 50 feet, general fitness and ratings of their Parkinson's symptoms.
Researchers discovered that low intensity treadmill training resulted in the most consistent improvements in gait and mobility. People who were on the low intensity treadmill training performed better than the two other groups on the distance and speed tests. However, only stretching and resistance training improved the ratings on the Parkinson's disease scale.
"Contrary to evidence suggesting that high intensity exercise is the most effective, our results suggest that a combination of low intensity training and stretching-resistance training may achieve the greatest improvements for people with Parkinson's disease" said Shulman.
The study was supported by The Michael J. Fox Foundation for Parkinson's Research, The National Institute on Aging (NIA) Claude D. Pepper Older Americans Independence Center NIH grant P30-AG02874, VA Rehabilitation Research & Development Maryland Exercise and Robotics Center of Excellence, and the Baltimore VA Medical Center GRECC.
The American Academy of Neurology, an association of more than 22,500 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer's disease, stroke, migraine, multiple sclerosis, brain injury, epilepsy and Parkinson's disease.
For more information about the American Academy of Neurology and its upcoming Annual Meeting, visit http://www.aan.com.
Dr. Shulman will be available for media questions during a press conference at 4:30 p.m. ET/10:30 a.m. HST, on Monday, April 11, 2011, in Room 325B of the Hawaii Convention Center in Honolulu. Please contact Rachel Seroka, email@example.com, to receive conference call information for those reporters covering the press conference off-site.
Dr. Shulman is available for advance interviews as well. Please contact Rachel Seroka, firstname.lastname@example.org, to schedule an advance interview.
To access non-late-breaking abstracts to be presented at the 2011 AAN Annual Meeting, visit http://www.aan.com/go/am11/science. Late-breaking abstracts will not be posted online in advance of the meeting and are embargoed until the date and time of presentation at the AAN Annual Meeting in Honolulu or unless otherwise noted by the Academy's Media and Public Relations Department.
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