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PUBLIC RELEASE DATE:
25-Apr-2011

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Contact: Sharon Butler
Sharon_Butler@rush.edu
312-942-7816
Rush University Medical Center

Higher levels of social activity decrease the risk of cognitive decline

If you want to keep your brain healthy, it turns out that visiting friends, attending parties, and even going to church might be just as good for you as crossword puzzles.

According to research conducted at Rush University Medical Center, frequent social activity may help to prevent or delay cognitive decline in old age. The study has just been posted online in the Journal of the International Neuropsychological Society.

The researchers were especially careful in their analysis to try to rule out the possibility that cognitive decline precedes, or causes, social isolation, and not the reverse.

"It's logical to think that when someone's cognitive abilities break down, they are less likely to go out and meet friends, enjoy a camping trip, or participate in community clubs. If memory and thinking capabilities fail, socializing becomes difficult," said lead researcher Bryan James, PhD, postdoctoral fellow in the epidemiology of aging and dementia in the Rush Alzheimer's Disease Center. "But our findings suggest that social inactivity itself leads to cognitive impairments."

The study included 1,138 older adults with a mean age of 80 who are participating in the Rush Memory and Aging Project, an ongoing longitudinal study of common chronic conditions of aging. They each underwent yearly evaluations that included a medical history and neuropsychological tests.

Social activity was measured based on a questionnaire that asked participants whether, and how often, in the previous year they had engaged in activities that involve social interaction--for example, whether they went to restaurants, sporting events or the teletract (off-track betting) or played bingo; went on day trips or overnight trips; did volunteer work; visited relatives or friends; participated in groups such as the Knights of Columbus; or attended religious services.

Cognitive function was assessed using a battery of 19 tests for various types of memory (episodic, semantic and working memory), as well as perceptual speed and visuospatial ability.

At the start of the investigation, all participants were free of any signs of cognitive impairment. Over an average of five years, however, those who were more socially active showed reduced rates of cognitive decline. On average, those who had the highest levels of social activity (the 90th percentile) experienced only one quarter of the rate of cognitive decline experienced by the least socially active individuals. Other variables that might have accounted for the increase in cognitive decline--such as age, physical exercise, and health--were all ruled out in the analysis.

Why social activity plays a role in the development of cognitive problems is not clear. According to James, one possibility is that "social activity challenges older adults to participate in complex interpersonal exchanges, which could promote or main efficient neural networks in a case of 'use it or lose it.'"

Future research is needed to determine whether interventions aimed at increasing late-life social activity can play a part in delaying or preventing cognitive decline, James said.

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Other researchers at Rush involved in the study were Robert Wilson, PhD, Lisa Barnes, PhD, and David Bennett, MD.

Rush is a not-for-profit academic medical center comprising Rush University Medical Center, Rush University, Rush Oak Park Hospital and Rush Health.

Rush is currently constructing a 14-floor, 806,000-square-foot hospital building near the corner of Ashland Avenue and the Eisenhower Expressway. The new hospital, scheduled to open in 2012, is the centerpiece of a $1 billion, ten-year campus redevelopment plan called the Rush Transformation, which also includes completion of a new orthopedics building, a new parking garage and central power plant, renovations of selected existing buildings and demolition of obsolete buildings. In January, Rush opened the new Rush University Cancer Center in completely renovated facilities in its Professional Buildings. The new hospital is designed and built to conserve energy and water, reduce waste and use sustainable building materials. Rush is seeking Leadership in Energy and Environmental Design (LEED) gold certification from the U.S. Green Building Council. It will be the first full-service, "green" hospital in Chicago.

Rush's mission is to provide the best possible care for its patients. Educating tomorrow's health care professional, researching new and more advanced treatment options, transforming its facilities and investing in new technologies--all are undertaken with the drive to improve patient care now, and for the future.



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