Increased consumption of ground beef or processed meat is positively associated with aggressive prostate cancer, according to a study published Nov. 23 in the online journal PLoS ONE.
The research team, led by John Witte of University of California, San Francisco, also found that the correlation was primarily driven by red meat that was grilled or barbequed, especially when well done.
They suggest that this result, which was determined based on the meat consumption habits of about 1,000 male participants, is due to increased levels of carcinogens in meat prepared these ways. The report furthers previous findings of the correlation between meat consumption and prostate cancer, and may help determine particular compounds that could be targeted for prostate cancer prevention.
Citation: Punnen S, Hardin J, Cheng I, Klein EA, Witte JS (2011) Impact of Meat Consumption, Preparation, and Mutagens on Aggressive Prostate Cancer. PLoS ONE 6(11): e27711. doi:10.1371/journal.pone.0027711
Financial Disclosure: The authors would like to acknowledge support from the NIH grants CA88164 and CA127298. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Competing Interest Statement: The authors have declared that no competing interests exist.
PLEASE LINK TO THE SCIENTIFIC ARTICLE IN ONLINE VERSIONS OF YOUR REPORT (URL goes live after the embargo ends):
Disclaimer: This press release refers to upcoming articles in PLoS ONE. The releases have been provided by the article authors and/or journal staff. Any opinions expressed in these are the personal views of the contributors, and do not necessarily represent the views or policies of PLoS. PLoS expressly disclaims any and all warranties and liability in connection with the information found in the release and article and your use of such information.
About PLoS ONE
PLoS ONE is the first journal of primary research from all areas of science to employ a combination of peer review and post-publication rating and commenting, to maximize the impact of every report it publishes. PLoS ONE is published by the Public Library of Science (PLoS), the open-access publisher whose goal is to make the world's scientific and medical literature a public resource.
All works published in PLoS ONE are Open Access. Everything is immediately available--to read, download, redistribute, include in databases and otherwise use--without cost to anyone, anywhere, subject only to the condition that the original authors and source are properly attributed. For more information about PLoS ONE relevant to journalists, bloggers and press officers, including details of our press release process and our embargo policy, see the EveryONE blog at http://everyone.