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PUBLIC RELEASE DATE:
13-Dec-2011

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Contact: Clare Weaver
press@plos.org
44-122-344-2834
PLOS

Self-epilation is an acceptable alternative to surgery in patients with mild trachomatous trichiasis

Self-epilation is an acceptable alternative to surgery in patients with mild trachomatous trichiasis

Teaching patients with mild trachomatous trichiasis--a leading cause of blindness in low resource countries in which chronic conjunctivitis leads to scarring causing the eyelids to turn inwards and the eye lashes to rub the eye causing pain, corneal damage, and visual impairment--to safely pull out the eyelashes touching their eye (epilation) using clean forceps, is an acceptable alternative to surgery to preserving vision. Furthermore, epilation may have additional advantages as surgical services are likely to remain unacceptable, inaccessible or prohibitively expensive for many people with the condition.

These findings from a large trial involving 1300 people in Ethiopia (the country with the highest rates of trachoma in the world) and published in this week's PLoS Medicine, leave the authors, led by Matthew Burton from the London School of Hygiene and Tropical Medicine, to conclude that although surgery should be performed for trachomatous trichiasis whenever possible, epilation should be considered when surgery is not available or is declined by the patient: in reality, a large majority of the approximately 8 million people who have trachomatous trichiasis are not receiving surgical treatment and given the enormous backlog of untreated cases, surgery is unlikely to be available to very large numbers of people living with trichiasis for at least the medium term.

The authors say "Where surgery is available and patients are willing to accept it, surgery should be performed, as the disease tends to progress, albeit quite slowly. However, we suggest that for individuals with minor trichiasis (who represent about half of all those with trachomatous trichiasis) epilation should be considered where surgery is either not available or declined by the patient."

In another study published in this week's PLoS Medicine, the same authors found that if surgery for trichiasis is performed, using absorbable sutures is as effective as silk sutures but has the added advantage of eliminating the need for patients to return to the clinic (often having to travel great distances) soon after their operation to have their sutures removed. The authors therefore suggest that trachoma control programs should now consider the potential logistical advantages of using absorbable sutures rather than silk sutures during trichiasis surgery despite the lack of any apparent clinical difference between the two suture types.

The authors say: "The logistical advantages of using absorbable sutures should be taken into consideration when considering the choice of suture material."

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Surgery Versus Epilation for the Treatment of Minor Trichiasis in Ethiopia: A Randomised Controlled Noninferiority Trial

Funding: This study was funded by grants from the Band Aid Foundation (via Fight For Sight) and The Wellcome Trust (080741/Z/06/Z). Johnson & Johnson donated all sutures. Tweezerman donated all forceps. Tweezerman made a donation towards the production costs of a trichiasis surgery training DVD. No funding bodies had any role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing Interests: PTK is a member of the Scientific Advisory Boards for Alcon and Bausch & Lomb. All other authors have declared that no competing interests exist.

Citation: Rajak SN, Habtamu E, Weiss HA, Kello AB, Gebre T, et al. (2011) Surgery Versus Epilation for the Treatment of Minor Trichiasis in Ethiopia: A Randomised Controlled Noninferiority Trial. PLoS Med 8(12): e1001136. doi:10.1371/journal.pmed.1001136

Absorbable Versus Silk Sutures for Surgical Treatment of Trachomatous Trichiasis in Ethiopia: A Randomised Controlled Trial

Funding: This study was funded by grants from the Band Aid Foundation (via Fight For Sight) and The Wellcome Trust (080741/Z/06/Z). All the sutures (silk and polyglactin-910) were donated by the manufacturer, Ethicon, Johnson & Johnson. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing Interests: PTK is a member of the Scientific Advisory Boards for Alcon and Bausch & Lomb. All other authors have declared that no competing interests exist.

Citation: Rajak SN, Habtamu E, Weiss HA, Kello AB, Gebre T, et al. (2011) Absorbable Versus Silk Sutures for Surgical Treatment of Trachomatous Trichiasis in Ethiopia: A Randomised Controlled Trial. PLoS Med 8(12): e1001137. doi:10.1371/journal.pmed.1001137

CONTACT FOR BOTH PAPERS:

Matthew Burton
London School of Hygiene and Tropical Medicine
Faculty of Infectious and Tropical Diseases
Keppel Street
London, WC1E 7HT
United Kingdom
44-207-927-2914
Matthew.Burton@lshtm.ac.uk



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