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PUBLIC RELEASE DATE:
8-Feb-2012

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Contact: Deborah Robison
drobison@sanfordburnham.org
407-745-2073
Sanford-Burnham Medical Research Institute
@SanfordBurnham

Moffitt, Sanford-Burnham and Florida Hospital create Personalized Medicine Partnership of Florida

TAMPA, Fla. and ORLANDO, Fla. - Moffitt Cancer Center, Sanford-Burnham Medical Research Institute and Florida Hospital have announced they will collaborate on the creation of a Personalized Medicine Partnership of Florida (PMP Florida). The partnership will conduct collaborative research to accelerate discovery and develop new treatments in the areas of cancer and metabolic diseases, including obesity, diabetes and cardiovascular disease.

PMP Florida will revolutionize health care by creating partnerships among Florida-based centers of excellence in medical research and clinical care. Together, the organizations will develop and utilize new molecular and genomic technologies to discover, translate and personalize interventions for preventing and treating debilitating diseases more efficiently to improve health care outcomes while reducing costs.

PMP Florida will leverage Moffitt's Total Cancer Care™ to develop similar research and clinical protocols in other disease areas including metabolic diseases. The partnership will hasten the discovery and development of new treatments by bringing together the complementary strengths of Florida Hospital's large patient population and clinical research expertise; Sanford-Burnham's fundamental research expertise and technology platforms; and Moffitt's biospecimen bank, data warehouse and personalized medicine capabilities.

"As a statewide resource for cancer research and treatment Moffitt seeks to foster relationships such as these to maximize the state's investment in the overall health and well-being of patients," said William S. Dalton, Ph.D., M.D., CEO and center director of Moffitt. "We feel this partnership will enhance Florida's national and international reputation in the discovery, translation, delivery and dissemination of care."

Total Cancer Care is a treatment path that begins by mapping the more than 30,000 genes that make up a tumor to find its own unique genetic fingerprint. Through personalized medicine, Moffitt is working to create individualized therapies that are specific to each patient's type of cancer, and the way each person responds to the disease and treatment therapies. The approach includes medical, nutritional, psychological, social and physical considerations.

Collaborations between research and clinical organizations are increasing as a means to access complementary resources, attract more sizable grant revenues and enhance the translation of laboratory research to clinical application.

"PMP Florida is a multi-institutional model for combining research and clinical care expertise to advance personalized medical care. Sanford-Burnham will deploy our most advanced technologies to discover molecular signatures of disease that can provide insight for determining appropriate therapeutic interventions," said John C. Reed, MD, Ph.D., and CEO, Sanford-Burnham Medical Research Institute. "The technology platforms, collections of patient samples, and medical information sharing create a powerful combination for improving clinical outcomes and reducing health care costs."

Through PMP Florida, researchers at the partnering institutions will access a robust research and clinical care infrastructure. Bio-samples representing a variety of diseases will be derived from Florida Hospital's expansive patient population. Pilot projects will utilize Moffitt's genome mapping, information systems and clinical research protocols developed through Total Cancer Care. The research will be empowered by Sanford-Burnham's scientific expertise in genomics and metabolomics technology platforms.

"PMP Florida is a unique partnership including three organizations with very complementary areas of expertise and experience," said Dr. David Moorhead, senior vice president and chief medical officer at Florida Hospital. "Moffitt has demonstrated world class experience and competency in acquiring, categorizing and storing biologic specimens. Sanford-Burnham Medical Research Institute is renowned for its internationally recognized scientific faculty, multiple sophisticated diagnostic platforms and a commitment to transforming basic science research into clinically available treatments. Florida Hospital is the largest hospital in Florida with broad, innovative and superior clinical expertise. Together, our organizations will have the potential to quickly and successfully advance the scientific development and availability of personalized medicine and to benefit the economic development of our communities."

One of the objectives of the partnership is to attract industry clients, including pharmaceutical and biotech companies, who will want to utilize this unique resource for discovery and development of new advances in health care. This partnership will exemplify how personalized medicine discoveries made in research labs will improve health care in hospitals, clinics and medical offices in Florida and nationally.

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About Moffitt Cancer Center

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Located in Tampa, Moffitt Cancer Center is the only Florida-based National Cancer Institute Comprehensive Cancer Center, a designation that recognizes Moffitt's excellence in research and contributions to clinical trials, prevention and cancer control. Moffitt has 14 affiliates in Florida, one in Georgia, one in Pennsylvania and two in Puerto Rico. Moffitt is also a member of the National Comprehensive Cancer Network, a prestigious alliance of the country's leading cancer centers, and is listed in U.S. News & World Report as one of "America's Best Hospitals" for cancer.

About Sanford-Burnham Medical Research Institute

Sanford-Burnham Medical Research Institute is dedicated to discovering the fundamental molecular causes of disease and devising the innovative therapies of tomorrow. The Institute consistently ranks among the top five organizations worldwide for its scientific impact in the fields of biology and biochemistry (defined by citations per publication) and currently ranks third in the nation in NIH funding among all laboratory-based research institutes. Sanford-Burnham is a highly innovative organization, currently ranking second nationally among all organizations in capital efficiency of generating patents, defined by the number of patents issued per grant dollars awarded, according to government statistics.

Sanford-Burnham utilizes a unique, collaborative approach to medical research and has established major research programs in cancer, neurodegeneration, diabetes, and infectious, inflammatory, and childhood diseases. The Institute is especially known for its world-class capabilities in stem cell research and drug discovery technologies. Sanford-Burnham is a U.S.-based, non-profit public benefit corporation, with operations in San Diego (La Jolla), Santa Barbara, and Orlando (Lake Nona). For more information, please visit our website (http://www.sanfordburnham.org) or blog (http://beaker.sanfordburnham.org). You can also receive updates by following us on Facebook and Twitter.

About Florida Hospital

Opened in 1908, Florida Hospital is a faith-based institution focused on providing whole person care. It is one of the largest not-for-profit hospitals in the country, caring for more than a million patient visits per year - more than any other hospital in the country, according to the American Hospital Association. The more than 2,000-bed system is comprised of eight hospitals, including the Walt Disney Pavilion at Florida Hospital for Children, 30 outpatient facilities and 20 Centra Care locations throughout Central Florida.

Florida Hospital provides a wide range of health services, including many nationally and internationally recognized programs in cardiology, cancer, women's medicine, neurosciences, diabetes, orthopedics, pediatrics and advanced surgical programs. Florida Hospital is a designated statutory teaching hospital and also trains physicians from all around the world on the newest technologies. With advanced research and industry partnerships, Florida Hospital seeks to extend and improve the quality of lives through the translation of fundamental scientific discoveries to the diagnosis and treatment of human disease. For more information, please visit http://www.floridahospital.com.

Follow Florida Hospital on Facebook: http://www.facebook.com/FloridaHospital

Follow Florida Hospital on Twitter: @Florida Hospital

Follow Florida Hospital on YouTube: FLHospital



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