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PUBLIC RELEASE DATE:
11-Nov-2013

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Contact: Kat Snodgrass
media@sfn.org
202-962-4090
Society for Neuroscience

Nurture impacts nature: Experiences leave genetic mark on brain, behavior

New studies show life events influence genes important for memory and drug use

SAN DIEGO New human and animal research released today demonstrates how experiences impact genes that influence behavior and health. Today's studies, presented at Neuroscience 2013, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health, provide new insights into how experience might produce long-term brain changes in behaviors like drug addiction and memory formation.

The studies focus on an area of research called epigenetics, in which the environment and experiences can turn genes "on" or "off," while keeping underlying DNA intact. These changes affect normal brain processes, such as development or memory, and abnormal brain processes, such as depression, drug dependence, and other psychiatric disease and can pass down to subsequent generations.

Today's new findings show that:

Other recent findings discussed show that:

"DNA may shape who we are, but we also shape our own DNA," said press conference moderator Schahram Akbarian, of the Icahn School of Medicine at Mount Sinai, an expert in epigenetics. "These findings show how experiences like learning or drug exposure change the way genes are expressed, and could be incredibly important in developing treatments for addiction and for understanding processes like memory."

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This research was supported by national funding agencies such as the National Institutes of Health, as well as private and philanthropic organizations. Find more information on epigenetics at BrainFacts.org.



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