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PUBLIC RELEASE DATE:
2-Dec-2013

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Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research

Why does cognitive dysfunction appear after subarachnoid hemorrhage?

IMAGE: Fewer synaptosomal-associated protein-25 positive cells were found in the cortex 1 day after subarachnoid hemorrhage.

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Synaptosomal-associated protein-25 is an important factor for synaptic functions and cognition. Prof. Zhong Wang and team from the First Affiliated Hospital of Soochow University, China verified that synaptosomal-associated protein-25 expression in the temporal lobe, hippocampus, and cerebellum significantly lower at days 1 and 3 following subarachnoid hemorrhage using immunohistochemical staining and western blot analysis. Synaptosomal-associated protein-25 expression was significantly lower following subarachnoid hemorrhage, which may be related to cognitive disorders after subarachnoid hemorrhage. These findings were published in the Neural Regeneration Research (Vol. 8, No. 29, 2013).

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Article: " Expression of synaptosomal-associated protein-25 in the rat brain after subarachnoid hemorrhage," by Gang Chen1, Tong Hu1, 2, Qi Li1, Jianke Li1, Yang Jia1, Zhong Wang1 (1 Department of Neurosurgery, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China; 2 Department of Neurosurgery, Yixing People's Hospital, Yixing 214200, Jiangsu Province, China)

Chen G, Hu T, Li Q, Li JK, Jia Y, Wang Z. Expression of synaptosomal-associated protein-25 in the rat brain after subarachnoid hemorrhage. Neural Regen Res. 2013;8(29):2693-2702.

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
http://www.nrronline.org/

Full text: http://www.sjzsyj.org/CN/article/downloadArticleFile.do?attachType=PDF&id=743



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