Bethesda, MD - This 2014 FASEB Science Research Conference focuses on recent advances in our understanding of the pathogenic mechanisms underlying the cystic renal diseases and the development of therapies to slow down their progression. The polycystic kidney diseases (PKD) are a group of inherited disorders that result not only in cyst development in the kidney, but also produce a range of extra-renal phenotypic manifestations.
All the PKD related disorders, including ADPKD, ARPKD and nephronophthisis, appear to be linked to defects in primary cilia, and as such they are called ciliopathies. PKD research is presently one of the most exciting areas of renal research. Increased understanding of the cellular basis of disease and the complex signaling pathways altered in cystic tissues has led to a flurry of activity to test possible therapeutic agents in animal models and more recently in human trials. Research is presently ongoing from the most basic to phase III trials and so, as the title of the conference suggests, this disorder truly encompasses all areas from molecular mechanism to therapy.
The goals of this meeting are:
- To assemble an interdisciplinary program of 30-40 basic scientists and clinical researchers who are at the forefront of PKD research to provide a comprehensive update on recent advances in PKD
- To provide a format where trainees and junior investigators can present, discuss and learn, with the goal of exciting them about PKD and inspiring them to become the next generation of PKD researchers
- To generate a platform for informed discussion to help resolve unanswered questions about PKD and to promote collaboration
- To promote the development of novel therapies for PKD by juxtaposing basic scientists, clinical investigators, and representatives of the pharmaceutical industry.
FASEB has announced a total of 35 Science Research Conferences (SRC) in 2014. Registration opens January 17, 2014. For more information about an SRC, view preliminary programs, or find a listing of all our 2014 SRCs, please visit http://www.
Since 1982, FASEB SRC has offered a continuing series of inter-disciplinary exchanges that are recognized as a valuable complement to the highly successful society meetings. Divided into small groups, scientists from around the world meet intimately and without distractions to explore new approaches to those research areas undergoing rapid scientific changes.