Washington, DC (February 20, 2014) — In addition to experiencing negative health effects from their disease, patients with chronic kidney disease (CKD) are also at risk of experiencing hazardous events potentially related to medical treatments they receive. A study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN) finds that low blood sugar and high blood potassium being common complications of their medical care.
Patients with CKD are susceptible to experiencing harm related to the care they receive due to their impaired kidney function and the complexity of the medical treatments they undergo.
Some studies have assessed the harms that CKD patients experience when they're hospitalized, but most of the care they receive is delivered outside of the hospital. Jennifer Ginsberg, Jeffrey Fink, MD (University of Maryland School of Medicine), and their colleagues examined 267 CKD patients enrolled in the ongoing Safe Kidney Care study, which attempts to determine the frequency of complications of medical care pertinent to the outpatient treatment of patients with CKD. The researchers looked for patient-reported adverse safety incidents (class I), which are reported hazardous events or symptoms that study participants attribute to a medication, as well as actionable safety findings (class II), which are hazardous clinical disturbances detected at study evaluations that have the potential to be corrected with treatment or medication modification.
Among the major findings:
"Disease-specific adverse safety event events are strikingly common in CKD and in the setting of medications that can account for such events. It is possible that efforts to prevent these unintended events will reduce the rate of renal function loss and poor outcomes in patients with CKD," said Dr. Fink.
Study co-authors include Min Zhan, PhD, Clarissa Diamantidis, MD, Corinne Woods, RPh, and Jingjing Chen.
Disclosures: The authors reported no financial disclosures.
The article, entitled "Patient-Reported and Actionable Safety Events in CKD," will appear online at http://jasn.asnjournals.org/ on February 20, 2014.
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