image: At 14 days after cerebral ischemia/reperfusion injury, in the HUCB-MSC + electro-acupuncture group, the number of vascular endothelial growth factor-positive cells around the ischemic focus in rats was increased, but the cells were irregular in shape. HUCB-MSCs: human umbilical cord blood-derived mesenchymal stem cells. view more
Credit: <i>Neural Regeneration Research</i>
Mesenchymal stem cell transplantation is a novel means of treating cerebral ischemia/reperfusion, and can promote angiogenesis and neurological functional recovery. Acupuncture at Conception and Governor vessels also has positive effects as a treatment for cerebral ischemia/reperfusion. Therefore, Prof. Haibo Yu and co-workers from Affiliated Shenzhen Traditional Chinese Medicine Hospital, Guangzhou University of Chinese Medicine in China hypothesized that electro-acupuncture at Conception and Governor vessels plus mesenchymal stem cell transplantation may have better therapeutic effects on the promotion of angiogenesis and recovery of neurological function than either treatment alone. In their study reported in the Neural Regeneration Research (Vol. 9, No. 1, 2014), human umbilical cord blood-derived mesenchymal stem cells (HUCB-MSCs) were isolated, cultured and transplanted into the brains of cerebral ischemia/reperfusion rats. Electro-acupuncture was also applied. The researchers found that the combined intervention provided a better outcome than mesenchymal stem cell transplantation alone, demonstrating that electro-acupuncture at Conception and Governor vessels and mesenchymal stem cell transplantation have synergetic effects on promoting neurological function recovery and angiogenesis in rats after cerebral ischemia/reperfusion.
Article: "Electro-acupuncture at Conception and Governor vessels and transplantation of umbilical cord bloodderived mesenchymal stem cells for treating cerebral ischemia/reperfusion injury" by Haibo Yu1, Pengdian Chen1, Zhuoxin Yang2, Wenshu Luo1, Min Pi1, Yonggang Wu1, Ling Wang1 (1 Affiliated Shenzhen Traditional Chinese Medicine Hospital, Guangzhou University of Chinese Medicine, Shenzhen 518033, Guangdong Province, China; 2 Affiliated Shenzhen Maternity & Child Healthcare Hospital, Southern Medical University, Shenzhen 518028, Guangdong Province, China)
Yu HB, Chen PD, Yang ZX, Luo WS, Pi M, Wu YG, Wang L. Electro-acupuncture at Conception and Governor vessels and transplantation of umbilical cord blood-derived mesenchymal stem cells for treating cerebral ischemia/reperfusion injury. Neural Regen Res. 2014;9(1):84-91.
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