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PUBLIC RELEASE DATE:
20-May-2014

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Contact: Kimberly Brown
brownk@aaps.org
703-248-4772
American Association of Pharmaceutical Scientists

Groundbreaking vaccine research unveiled at AAPS National Biotechnology Conference

Vaccines for tetanus and novel formulation for delivery to be presented; over 200 posters to be offered

SAN DIEGO (May 20, 2014) - Innovative vaccine research will be unveiled at the American Association of Pharmaceutical Scientists' (AAPS) National Biotechnology Conference (NBC). The meeting takes place Monday, May 19- Wednesday, May 21 at the Sheraton San Diego Hotel and Marina.

Designing a Novel Freeze-Stable Tetanus Vaccine

According to the World Health Organization, over half of all vaccines worldwide are destroyed due to freeze-damage. A lot of research is currently being conducted about issues associated with the cold-chain and freeze-damage of vaccines.

Aryo Sorayya, a freshman at Stanford University, and a team of researchers at HTD Biosystems are working to replace the freeze-sensitive, aluminum-based substances currently used in vaccines with freeze-stable, lipid nanoparticles (liposomes). The vaccine has been successfully tested and applied to make freeze-stable Tetanus vaccines, showing promise as a viable alternative to freeze-sensitive vaccines currently on the market.

Intradermal Delivery of High Volume Polymeric Nanoparticle Based Vaccine Formulation Using a Hollow Microneedle System

Human skin is the first line of defense where the body engages microbes in the real world. In an effort to develop more effective vaccines, a formulation has been developed of particles that mimic viruses in size and shape.

A team of researchers from the University of Minnesota have demonstrated the capability of delivering particle based vaccines directly into the skin. The delivery device is equipped with needles much shorter than conventional needles used for intramuscular and subcutaneous injection.

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About AAPS: The American Association of Pharmaceutical Scientists (AAPS) is a professional, scientific organization of approximately 11,000 members employed in academia, industry, government, and other research institutes worldwide. Founded in 1986, AAPS provides a dynamic international forum for the exchange of knowledge among scientists to serve the public and enhance their contributions to health. AAPS offers timely scientific programs, on-going education, information resources, opportunities for networking, and professional development. Visit http://www.aaps.org today. Follow us on Twitter @AAPSComms; official Twitter hashtag for the meeting is #2014NBC.

About the AAPS National Biotechnology Conference: The 2014 AAPS National Biotechnology Conference (NBC) will gather scientists from industry, government, and academia for three days of educational offerings specifically geared toward the biotechnology sector of the pharmaceutical sciences. Visit http://www.aaps.org/nationalbiotech/ for more information.

Editor's Note: Registration is complimentary for members of the media. All abstracts presented are available upon request. To register for the meeting or set up an interview with an expert, please contact Stacey May on-site at (703) 459-7677.



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