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PUBLIC RELEASE DATE:
2-Jun-2014

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Contact: Chris Melvin
chris.melvin@bbsrc.ac.uk
01-793-414-694
Biotechnology and Biological Sciences Research Council

UK invests in world's most advanced crystallography facility

The UK's structural biology community will have access to the most advanced crystallography technology in the world thanks to a 5.64M investment from UK research funders.

The Biotechnology and Biological Sciences Research Council (BBSRC), the Medical Research Council (MRC) and the Wellcome Trust will contribute the funds towards the European X-ray Free Electron Lasers (XFEL) project, under construction in Hamburg, Germany.

The money will guarantee UK researchers the chance to use serial femtosecond crystallography (SFX) at the European XFEL, a cutting-edge technique to determine the three-dimensional shape of biological molecules at high resolution and incredible speeds.

A hub for scientists who wish to use SFX will also be established at the Diamond Light Source in Oxfordshire to train and prepare UK researchers.

Crystallography is used to determine the 3D structure of the molecular machines of life, and has transformed our understanding of living things. It can be used to develop new pharmaceutical drugs, antibiotics and new sources of chemicals and energy.

From 2017 the European XFEL facilities will represent a new generation of crystallography technology and will allow scientists to work at finer resolutions and faster speeds than ever before.

Colin Miles, Head of Sector in Industrial Biotechnology and Bioenergy at the Biotechnology and Biological Sciences Research Council, said: "The European XFEL will enable cutting-edge crystallography research and it is important for world-leading structural biologists from the UK to have access to these facilities.

"By investing in the European XFEL consortium, BBSRC, MRC and the Wellcome Trust will ensure that scientists based in the UK can use these facilities and stay at the forefront of their field, conducting research that has important potential both economically and socially."

Michael Dunn, Head of Genetics and Molecular Science at the Wellcome Trust said: "The incredible power of the European XFEL will allow researchers to look at the smallest building blocks of life in new detail, from 'filming' biochemical reactions to studying drug targets of the future. Structural biology has been the basis for some of the most exciting developments in biomedical science, and investing in new technology is a vital part of the field's continuing success."

Over five years between 2014 and 2019 the UK funders will contribute 5.64M to the European XFEL project.

2014 is the United Nation's International Year of Crystallography, reflecting its global importance and contribution to human life.

You can find out more about the European XFEL project at: http://www.xfel.eu/

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Contact:

Chris Melvin, BBSRC Media Officer, 01793 414694, chris.melvin@bbsrc.ac.uk

About BBSRC

The Biotechnology and Biological Sciences Research Council (BBSRC) invests in world-class bioscience research and training on behalf of the UK public. Our aim is to further scientific knowledge, to promote economic growth, wealth and job creation and to improve quality of life in the UK and beyond.

Funded by Government, and with an annual budget of around 467M (2012-2013), we support research and training in universities and strategically funded institutes. BBSRC research and the people we fund are helping society to meet major challenges, including food security, green energy and healthier, longer lives. Our investments underpin important UK economic sectors, such as farming, food, industrial biotechnology and pharmaceuticals.

For more information about BBSRC, our science and our impact see: http://www.bbsrc.ac.uk

For more information about BBSRC strategically funded institutes see: http://www.bbsrc.ac.uk/institutes

About MRC

The Medical Research Council has been at the forefront of scientific discovery to improve human health. Founded in 1913 to tackle tuberculosis, the MRC now invests taxpayers' money in some of the best medical research in the world across every area of health. Twenty-nine MRC-funded researchers have won Nobel prizes in a wide range of disciplines, and MRC scientists have been behind such diverse discoveries as vitamins, the structure of DNA and the link between smoking and cancer, as well as achievements such as pioneering the use of randomised controlled trials, the invention of MRI scanning, and the development of a group of antibodies used in the making of some of the most successful drugs ever developed. Today, MRC-funded scientists tackle some of the greatest health problems facing humanity in the 21st century, from the rising tide of chronic diseases associated with ageing to the threats posed by rapidly mutating micro-organisms. http://www.mrc.ac.uk

About the Wellcome Trust

The Wellcome Trust is a global charitable foundation dedicated to achieving extraordinary improvements in human and animal health. It supports the brightest minds in biomedical research and the medical humanities. The Trust's breadth of support includes public engagement, education and the application of research to improve health. It is independent of both political and commercial interests.http://www.wellcome.ac.uk



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