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PUBLIC RELEASE DATE:
29-Jul-2014

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Contact: Michael Burton
michael.burton@heart.org
214-706-1236
American Heart Association
www.twitter.com/HeartNews

Time of arrival at hospital impacts time to treatment and survival of heart attack patients

American Heart Association Rapid Access Journal Report

Going to the hospital for a heart attack during evenings, weekends and holidays increases your risk of dying 13 percent compared with people arriving during workday hours, according to new research in the American Heart Association journal Circulation: Cardiovascular Quality and Outcomes.

Every year, more than 250,000 people experience an ST elevation myocardial infarction (STEMI), the most severe type of heart attack caused by a complete blockage of blood flow to the heart. To prevent death, it's critical to restore blood flow as quickly as possible by surgically opening the blocked vessel or administering intravenous clot-busting medication.

"Slower door-to-balloon times for people who arrived at the hospital during off hours is likely due to staffing. In the middle of the night, the hospital catheterization lab where angioplasty and other artery-opening procedures are performed is closed," said Jorge Saucedo, M.D., lead author of the study and chief of cardiology and co-director of the Cardiovascular Institute at Northshore University Health System in Evanston, Ill. "When a heart attack patient comes to the emergency department at 1 a.m., the emergency staff activate the pagers. Doctors need to drive to the hospital, get things set up in the cath lab, and it takes time."

Researchers compared the care provided and survival for 27,270 STEMI patients who arrived during off hours versus 15,972 STEMI patients who arrived during regular business hours between January 2007 and September 2010 at 447 U.S. hospitals.

Patients who arrived at the emergency room during regular workday hours had an average door-to-balloon time of 56 minutes compared with 72 minutes for patients who arrived during evenings, weekends and holidays. The American Heart Association's guidelines for the treatment of STEMI patients recommends angioplasty in 90 minutes or less.

During angioplasty, a catheter is threaded into the heart with a deflated balloon at the tip. The balloon is then inflated in the artery where blood flow has been reduced or blocked. Door-to-balloon time is the period from the patient's arrival to the hospital until the blockage is opened by angioplasty. Following angioplasty, doctors may also implant a mesh tube called a stent to help keep the artery open.

Researchers also found:

"The fact that treatments were similar in both groups and that only door-to-balloon time lagged slightly is a credit to continually raising awareness and educating providers about the Mission: Lifeline® guidelines," said Saucedo. "Over the past decade, these cardiac emergency protocols carried out by multiple institutions across the country have made a huge impact in saving lives. Yes, there is opportunity for improvement, but this really is a huge success."

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Co-authors are: Tarun W. Dasari1, M.D., M.P.H.; Matthew T. Roe, M.D., M.H.S.; Anita Y. Chen, M.S.; Eric D. Peterson, M.D., M.P.H.; Robert P. Giugliano, M.D., S.M.; and Gregg C. Fonarow, M.D. Author disclosures are on the manuscript.

Mission: Lifeline® was created by the American Heart Association as a response to missed opportunities for prompt, appropriate STEMI treatment. Learn more about STEMI systems of care or about STEMI and cardiac resuscitation systems of care by choosing one of the options below.

Additional Resources:

  • Mission: Lifeline: Improving Cardiac and STEMI and Cardiac Resuscitation
  • Follow AHA/ASA news on Twitter @HeartNews.

    Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association's policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations are available at http://www.heart.org/corporatefunding.



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