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PUBLIC RELEASE DATE:
28-Jul-2014

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Contact: Erin Tornatore
erin.tornatore@childrens.harvard.edu
617-919-3110
The JAMA Network Journals
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Electronic screening tool to triage teenagers and risk of substance misuse

Bottom Line: An electronic screening tool that starts with a single question to assess the frequency of substance misuse appears to be an easy way to screen teenagers who visited a physician for routine medical care.

Author: Sharon Levy, M.D., M.P.H., of Boston Children's Hospital, and colleagues.

Background: Substance use can cause illness and death in adolescents. Screening adolescents and intervening if there is substance use can reduce the burden of addiction. The American Academy of Pediatrics and other professional organizations recommend that primary care physicians screen adolescents for substance use.

How the Study Was Conducted: The authors examined use of an electronic screening and assessment tool to triage adolescents into four categories regarding nontobacco substance use: no past-year alcohol or drug use, past-year use with a substance use disorder (SUD), mild or moderate SUD and severe SUD. The tool also can assess tobacco use. The study included 216 adolescent patients (ages 12 to 17 years) from outpatient centers at a pediatric hospital who completed the screening from June 2012 through March 2013. The screening started with a single question that assessed the frequency of past-year use in eight categories of substances, including alcohol, marijuana, cocaine and prescription drugs. Patients who reported use were asked additional questions.

Results: For nontobacco substance use, 123 patients (57.7 percent) reported no past-year use, 49 (23 percent) reported use but didn't meet the criteria for SUD, 22 (10.3 percent) met the criteria for mild or moderate SUD and 19 (8.9 percent) met the criteria for severe SUD. Sensitivity and specificity were 100% and 84% for identifying non-tobacco substance use, 90% and 94% for substance use disorders, 100% and 94% for severe SUD, and 75% and 98% for nicotine dependence. No significant differences were found in sensitivity or specificity between the full tool and the frequency-only questions.

Conclusion: "Our findings suggest that frequency screening questions are also a valid and efficient means of triaging alcohol and drug use into clinically meaningful risk levels in adolescents."

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(JAMA Pediatr. Published online July 28, 2014. doi:10.1001/jamapediatrics.2014.774. Available pre-embargo to the media at http://media.jamanetwork.com.)

Editor's Note: The study was supported by grants from the National Institute on Drug Abuse. Please see article for additional information, including other authors, author contributions and affiliations, etc.

Editorial: Substance Misuse Among Teens, to Screen or Not to Screen In a related editorial, Geetha A. Subramaniam, M.D., D.F.A.P.A., and Nora D. Volkov, M.D., of the National Institute of Drug Abuse, Bethesda, Md., write: "Strategies to disseminate the use of this validated screening tool would need to overcome barriers to perform routine screening in pediatric primary care settings."

"Among these barriers are the lack of knowledge on how to screen for substances of abuse, the lack of training in or familiarity with the management of adolescents with substance use problems, and the burden on pediatric physicians to treat these patients within the time constraints of busy practices. Perhaps an even bigger barrier to widespread adoption is the lack of an evidence base to clinically guide the pediatric physician when substance misuse is uncovered in an adolescent," the authors continue.

"The study by Levy and colleagues represents a major advance, yet only the beginning of a larger, urgently needed evidence-gathering process to inform the utility of screening and the adequate management of substance misuse in adolescents by pediatric primary care physicians," they conclude.

(JAMA Pediatr. Published online July 28, 2014. doi:10.1001/jamapediatrics.2014.958. Available pre-embargo to the media at http://media.jamanetwork.com.)

Editor's Note: Please see article for additional information, including other authors, author contributions and affiliations, etc.

Media Advisory: To contact author Sharon Levy, M.D., M.P.H., call Erin Tornatore at 617-919-3110 or email erin.tornatore@childrens.harvard.edu. To contact editorial author Geetha A. Subramaniam, M.D., D.F.A.P.A., call Sheri Grabus at 301-443-6245 or email media@nida.nih.gov



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